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Volumn 13, Issue 3, 1999, Pages 369-375

Identification of a novel molecular partner of the E2A gene in childhood leukemia

Author keywords

E2A; Fusion genes; Pre B ALL

Indexed keywords

COMPLEMENTARY DNA;

EID: 0033045755     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2401338     Document Type: Article
Times cited : (32)

References (40)
  • 1
    • 0027195095 scopus 로고
    • Current status of cytogenetic research in childhood acute lymphoblastic leukemia
    • Raimondi SC. Current status of cytogenetic research in childhood acute lymphoblastic leukemia. Blood 1993; 81: 2237-2251.
    • (1993) Blood , vol.81 , pp. 2237-2251
    • Raimondi, S.C.1
  • 2
    • 0030056354 scopus 로고    scopus 로고
    • Chromosomal translocations involving the E2A gene in acute lymphoblastic leukemia: Clinical features and molecular pathogenesis
    • Hunger SP. Chromosomal translocations involving the E2A gene in acute lymphoblastic leukemia: clinical features and molecular pathogenesis. Blood 1996; 87: 1211-1224.
    • (1996) Blood , vol.87 , pp. 1211-1224
    • Hunger, S.P.1
  • 4
    • 0025064238 scopus 로고
    • Chromosomal translocation t(1;19) results in synthesis of a homeobox fusion mRNA that codes for a potential chimeric transcription factor
    • Nourse J, Mellentin JD, Galili N, Wilkinson J, Stanbridge E, Smith SD, Cleary ML. Chromosomal translocation t(1;19) results in synthesis of a homeobox fusion mRNA that codes for a potential chimeric transcription factor. Cell 1990; 60: 535-545.
    • (1990) Cell , vol.60 , pp. 535-545
    • Nourse, J.1    Mellentin, J.D.2    Galili, N.3    Wilkinson, J.4    Stanbridge, E.5    Smith, S.D.6    Cleary, M.L.7
  • 5
    • 0025137176 scopus 로고
    • A new homeobox gene contributes the DNA binding domain of the t(1;19) translocation protein in pre-B ALL
    • Kamps MP, Murre C, Sun X-H, Baltimore DA. A new homeobox gene contributes the DNA binding domain of the t(1;19) translocation protein in pre-B ALL. Cell 1990; 60: 547-555.
    • (1990) Cell , vol.60 , pp. 547-555
    • Kamps, M.P.1    Murre, C.2    Sun, X.-H.3    Baltimore, D.A.4
  • 7
    • 0026761786 scopus 로고
    • Hlf, a novel hepatic bZIP protein, shows altered DNA-binding properties following fusion to E2A in t(17;19) acute lymphoblastic leukemia
    • Hunger SP, Ohyashiki K, Toyama K, Cleary ML. Hlf, a novel hepatic bZIP protein, shows altered DNA-binding properties following fusion to E2A in t(17;19) acute lymphoblastic leukemia. Genes Dev 1992; 6: 1608-1620.
    • (1992) Genes Dev , vol.6 , pp. 1608-1620
    • Hunger, S.P.1    Ohyashiki, K.2    Toyama, K.3    Cleary, M.L.4
  • 9
    • 0026069091 scopus 로고
    • The t(1;19)(q23;p13) results in consistent fusion of E2A and PBX1 coding sequences in acute lymphoblastic leukemias
    • Hunger SP, Galili N, Carrol AJ, Crist WJ, Link MP, Cleary ML. The t(1;19)(q23;p13) results in consistent fusion of E2A and PBX1 coding sequences in acute lymphoblastic leukemias. Blood 1991; 77: 687-693.
    • (1991) Blood , vol.77 , pp. 687-693
    • Hunger, S.P.1    Galili, N.2    Carrol, A.J.3    Crist, W.J.4    Link, M.P.5    Cleary, M.L.6
  • 11
    • 0027486912 scopus 로고
    • New E2A/PBX1 fusion transcript in a patient with t(1;19)(q23;p13) acute lymphoblastic leukemia
    • Numata S-I, Kato K, Horibe K. New E2A/PBX1 fusion transcript in a patient with t(1;19)(q23;p13) acute lymphoblastic leukemia. Leukemia 1993; 7: 1441-1444.
    • (1993) Leukemia , vol.7 , pp. 1441-1444
    • Numata, S.-I.1    Kato, K.2    Horibe, K.3
  • 12
    • 0025185904 scopus 로고
    • Molecular analysis of the t(1;19)(q23;p13) breakpoint cluster region in pre-B cell acute lymphoblastic leukemias
    • Mellentin JD, Nourse J, Hunger SP, Smith SD, Cleary ML. Molecular analysis of the t(1;19)(q23;p13) breakpoint cluster region in pre-B cell acute lymphoblastic leukemias. Genes Chromos Cancer 1990; 2: 239-247.
    • (1990) Genes Chromos Cancer , vol.2 , pp. 239-247
    • Mellentin, J.D.1    Nourse, J.2    Hunger, S.P.3    Smith, S.D.4    Cleary, M.L.5
  • 13
    • 0028206833 scopus 로고
    • Two types of genomic rearrangements create alternative E2A-HLF fusion proteins in t(17;19)-ALL
    • Hunger SP, Devarai PE, Foroni L, Sacker-Walker LM, Cleary ML. Two types of genomic rearrangements create alternative E2A-HLF fusion proteins in t(17;19)-ALL. Blood 1994; 83: 2970-2977.
    • (1994) Blood , vol.83 , pp. 2970-2977
    • Hunger, S.P.1    Devarai, P.E.2    Foroni, L.3    Sacker-Walker, L.M.4    Cleary, M.L.5
  • 14
    • 0031029142 scopus 로고    scopus 로고
    • Cell transformation mediated by homodimeric E2A-HLF transcription factors
    • Inukai T, Inaba T, Yoshihara T, Look AT. Cell transformation mediated by homodimeric E2A-HLF transcription factors. Mol Cell Biol 1997; 17: 1417-1424.
    • (1997) Mol Cell Biol , vol.17 , pp. 1417-1424
    • Inukai, T.1    Inaba, T.2    Yoshihara, T.3    Look, A.T.4
  • 15
    • 0028144968 scopus 로고
    • DNA-binding and transcriptional regulatory properties of hepatic leukemia factor (HLF) and the t(17;19) acute lymphoblastic leukemia chimera E2A-HLF
    • Hunger SP, Brown R, Cleary ML. DNA-binding and transcriptional regulatory properties of hepatic leukemia factor (HLF) and the t(17;19) acute lymphoblastic leukemia chimera E2A-HLF. Mol Cell Biol 1994; 14: 5986-5996.
    • (1994) Mol Cell Biol , vol.14 , pp. 5986-5996
    • Hunger, S.P.1    Brown, R.2    Cleary, M.L.3
  • 16
    • 0026033596 scopus 로고
    • The human t(1;19) translocation in pre-B ALL produces multiple nuclear E2A-Pbx1 fusion proteins with differing transforming potentials
    • Kamps MP, Look AT, Baltimore D. The human t(1;19) translocation in pre-B ALL produces multiple nuclear E2A-Pbx1 fusion proteins with differing transforming potentials. Genes Dev 1991; 5: 358-368.
    • (1991) Genes Dev , vol.5 , pp. 358-368
    • Kamps, M.P.1    Look, A.T.2    Baltimore, D.3
  • 17
    • 0031018906 scopus 로고    scopus 로고
    • E2a-Pbx1 induces aberrant expression of tissue specific developmentally regulated genes when expressed in NIH3T3 fibroblasts
    • Fu X, Kamps MP. E2a-Pbx1 induces aberrant expression of tissue specific developmentally regulated genes when expressed in NIH3T3 fibroblasts. Mol Cell Biol 1997; 17: 1503-1512.
    • (1997) Mol Cell Biol , vol.17 , pp. 1503-1512
    • Fu, X.1    Kamps, M.P.2
  • 18
    • 0030991337 scopus 로고    scopus 로고
    • The highest affinity DNA element bound by Pbx complexes in t(1;19) leukemic cells fails to mediate cooperative DNA-binding or cooperative transactivation by E2a-Pbx1 and class I Hox proteins - Evidence for selective targeting of E2a-Pbx1 to a subset of Pbx-recognition elements
    • Knoepfler PS, Kamps MP. The highest affinity DNA element bound by Pbx complexes in t(1;19) leukemic cells fails to mediate cooperative DNA-binding or cooperative transactivation by E2a-Pbx1 and class I Hox proteins - evidence for selective targeting of E2a-Pbx1 to a subset of Pbx-recognition elements. Oncogene 1997; 14: 2521-2531.
    • (1997) Oncogene , vol.14 , pp. 2521-2531
    • Knoepfler, P.S.1    Kamps, M.P.2
  • 20
    • 0032529704 scopus 로고    scopus 로고
    • The chimeric E2A-HLF transcription factor abrogates p53-induced apoptosis in myeloid leukemia cells
    • Altura RA, Inukai T, Ashmun RA, Zambetti CP, Roussel MF, Look AT. The chimeric E2A-HLF transcription factor abrogates p53-induced apoptosis in myeloid leukemia cells. Blood 1998; 92: 1397-1405.
    • (1998) Blood , vol.92 , pp. 1397-1405
    • Altura, R.A.1    Inukai, T.2    Ashmun, R.A.3    Zambetti, C.P.4    Roussel, M.F.5    Look, A.T.6
  • 21
    • 0032581498 scopus 로고    scopus 로고
    • The gene encoding the granulocyte colony-stimulating factor receptor is a target for deregulation in pre-B ALL by the t(1;19)-specific oncoprotein E2a-Pbx1
    • De Lau WB, Hurenkamp J, Berendes P, Touw IP, Clevers HC, van Dijk MA. The gene encoding the granulocyte colony-stimulating factor receptor is a target for deregulation in pre-B ALL by the t(1;19)-specific oncoprotein E2A-Pbx1. Oncogene 1998; 17: 503-510.
    • (1998) Oncogene , vol.17 , pp. 503-510
    • De Lau, W.B.1    Hurenkamp, J.2    Berendes, P.3    Touw, I.P.4    Clevers, H.C.5    Van Dijk, M.A.6
  • 23
    • 0029093617 scopus 로고
    • B cell differentiation: Role of E2A and Pax5/BSAP transcription factors
    • Baker SJ, Reddy EP. B cell differentiation: role of E2A and Pax5/BSAP transcription factors. Oncogene 1995; 11: 413-426.
    • (1995) Oncogene , vol.11 , pp. 413-426
    • Baker, S.J.1    Reddy, E.P.2
  • 24
    • 0030879868 scopus 로고    scopus 로고
    • Regulation of the expression of cyclin dependent kinase inhibitor p21 by E2A and id proteins
    • Prabhu S, Ignatova A, Park ST, Sun XH. Regulation of the expression of cyclin dependent kinase inhibitor p21 by E2A and Id proteins. Mol Cell Biol 1997; 17: 5888-5896.
    • (1997) Mol Cell Biol , vol.17 , pp. 5888-5896
    • Prabhu, S.1    Ignatova, A.2    Park, S.T.3    Sun, X.H.4
  • 26
    • 0028148938 scopus 로고
    • The helix-loop-helix gene E2A is required for B cell formation
    • Zhuang Y, Soriano P, Weintraub H. The helix-loop-helix gene E2A is required for B cell formation. Cell 1994; 79: 875-884.
    • (1994) Cell , vol.79 , pp. 875-884
    • Zhuang, Y.1    Soriano, P.2    Weintraub, H.3
  • 27
    • 0029058035 scopus 로고
    • B-cell-specific DNA binding by an E47 homodimer
    • Shen C-P, Kadesch T. B-cell-specific DNA binding by an E47 homodimer. Mol Cell Biol 1995; 15: 4518-4524.
    • (1995) Mol Cell Biol , vol.15 , pp. 4518-4524
    • Shen, C.-P.1    Kadesch, T.2
  • 28
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-cloroform extraction
    • Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-cloroform extraction. Anal Biochem 1987; 162: 156-160.
    • (1987) Anal Biochem , vol.162 , pp. 156-160
    • Chomczynski, P.1    Sacchi, N.2
  • 30
    • 85038183297 scopus 로고    scopus 로고
    • www-bio.llnl.gov/bbrp/genome.
  • 31
    • 0028267931 scopus 로고
    • Molecular variants of the 1;19 chromosomal translocation in pediatric acute lymphoblastic leukemia (ALL)
    • Privitera E, Luciano A, Ronchetti D, Aricò M, Santostasi T, Basso G, Biondi A. Molecular variants of the 1;19 chromosomal translocation in pediatric acute lymphoblastic leukemia (ALL). Leukemia 1994; 8: 554-559.
    • (1994) Leukemia , vol.8 , pp. 554-559
    • Privitera, E.1    Luciano, A.2    Ronchetti, D.3    Aricò, M.4    Santostasi, T.5    Basso, G.6    Biondi, A.7
  • 35
    • 0032053822 scopus 로고    scopus 로고
    • Linkage of familial Wilms' tumor predisposition to chromosome 19 and two-locus model for the etiology of familial tumors
    • McDonald JM, Douglass EC, Fisher R, Geiser CF, Krill CE, Strong LC, Virshup D, Huff V. Linkage of familial Wilms' tumor predisposition to chromosome 19 and two-locus model for the etiology of familial tumors. Cancer Res 1998; 58: 1387-1390.
    • (1998) Cancer Res , vol.58 , pp. 1387-1390
    • McDonald, J.M.1    Douglass, E.C.2    Fisher, R.3    Geiser, C.F.4    Krill, C.E.5    Strong, L.C.6    Virshup, D.7    Huff, V.8
  • 38
    • 0027204066 scopus 로고
    • The E2A gene product contains two separable and functionally distinct transcription activation domains
    • Aronheim A, Shiran R, Rosen A, Walker MD. The E2A gene product contains two separable and functionally distinct transcription activation domains. Proc Natl Acad Sci USA 1993; 90: 8063-8067.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 8063-8067
    • Aronheim, A.1    Shiran, R.2    Rosen, A.3    Walker, M.D.4
  • 39
    • 0028089760 scopus 로고
    • Transformation properties of the E2a-Pbx1 chimeric oncoprotein: Fusion with E2a is essential, but the Pbx1 homeodomain is dispensable
    • Monika K, LeBrun DP, Dedera DA, Brown R, Cleary ML. Transformation properties of the E2a-Pbx1 chimeric oncoprotein: fusion with E2a is essential, but the Pbx1 homeodomain is dispensable. Mol Cell Biol 1994; 14: 8304-8310.
    • (1994) Mol Cell Biol , vol.14 , pp. 8304-8310
    • Monika, K.1    LeBrun, D.P.2    Dedera, D.A.3    Brown, R.4    Cleary, M.L.5
  • 40
    • 0031656237 scopus 로고    scopus 로고
    • The AD1 and AD2 transactivation domains of E2A are essential for the antiapoptotic activity of the chimeric oncoprotein E2A-HLF
    • Inukai T, Inaba T, Ikushima S, Look AT. The AD1 and AD2 transactivation domains of E2A are essential for the antiapoptotic activity of the chimeric oncoprotein E2A-HLF. Mol Cell Biol 1998; 18: 6035-6043.
    • (1998) Mol Cell Biol , vol.18 , pp. 6035-6043
    • Inukai, T.1    Inaba, T.2    Ikushima, S.3    Look, A.T.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.