X-ray microanalysis of melanin granules of retinal pigment epithelium and choroid in hereditary copper deficient mice (macular mice)

Experimental Eye Research

Volumn 68, Issue 1, 1999, Pages 59-66

  Mishima, Kazuaki ^a   Amemiya, Tsugio ^a   Takano, Kunio ^b  

^a NAGASAKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b NAGASAKI UNIVERSITY   (Japan)

Author keywords

Choroid; Copper deficiency; Freeze embedding method; Macular mouse; Melanin granules; Menkes' disease; Retinal pigment epithelium; X ray microanalysis

Indexed keywords

MELANIN;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHOROID; COPPER DEFICIENCY; HEMIZYGOSITY; MENKES SYNDROME; MOUSE; NONHUMAN; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN DETERMINATION; QUANTITATIVE ASSAY; X RAY MICROANALYSIS;

EID: 0033044824     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1006/exer.1998.0592     Document Type: Article

References (25)

1. Aguilar, M. J., Chadwick, D. L., Okuyama, K. and Kamoshita, S. (1966). Kinkey hair disease: I. Clinical and pathological features. J. Neuropathol. Exp. Neural. 25, 507-22.
2. Barr, F. E. (1983). Melanin: The organizing molecule. Med. Hypothesis 11, 1-140.
3. Bray, P. F. (1965). Sex-linked neurodegenerative disease associated with monilethrix. Pediatrics 36, 417-20.
4. Dake, Y. (1992). Electron histochemical examination of cytochrome oxidase in the retinal photoreceptor cell of copper deficient rats. Acta Histochem. Cytochem. 25, 371-8.
5. Danks, D. M., Stevens, B. J., Campbell, P. E., Gillespie, J. M., Walker-Smith, J., Blomfield, J. and Turner, B. (1972). Menkes' kinkey hair syndrome. Lancet i, 1100-3.
6. Dryja, T. P., O'Neil-Dryja, M. and Albert, D.M. (1979). Elemental analysis of melanins from hair, iris, choroid and retinal pigment epithelium. Invest. Ophthalmol Vis. Sci. 18, 231-5.
7. Heydorn, K., Damsgaard, E., Horn, N., Mikkelsen, M., Tygstrup, I., Vestermark, S. and Weber, J. (1975). Extra-hepatic storage of copper. A male foetus suspected of Menkes' disease. Hum. Genet, 29, 171-5.
8. Kodama, H. (1993). Recent development in menkes disease. J. Inher. Metab. Dis. 16, 791-9.
9. Mann, J. R., Camakaris, J., Danks, D. M. and Walliczek, E. G. (1979). Copper metabolism in mottled mouse mutants. Copper therapy of brindled (Mobr) mice. Biochem. J. 180, 605-12.
10. Martuza, R. L., Philippe, I., Fitzpatrick, T. B., Zwaan, J., Seki, Y. and Lederman, J. (1985). Melanin macroglobules as a cellular marker of neurofibromatosis: A quantitative study. Invest. Dermatol. 85, 347-50.
11. Meguro, Y., Kodama, H., Abe, T., Kobayashi, S., Kodama, Y. and Nishimura, M. (1991). Changes of copper level and cytochrome c oxidase activity in the macular mice with age. Brain Dev. 13, 184-6.
12. Menkes, J. H., Alter, M., Steigleder, G. K., Weakley, D. R. and Sung, J. H. (1962). A sex-linked recessive disorder with retardation of growth, peculiar hair, and focal cerebral and cerebellar degeneration. Pediatrics 29, 764-79.
13. Mishima, K., Dake, Y., Amemiya, T. and Nishimura, M. (1996). Electron microscopic study of retinas of macular mice. Graefe's Arch. Clin. Exp. Ophthalmol. 234, S 101-5.
14. Nagara, H., Yajima, K. and Suzuki, K. (1981). The effect of copper supplementation on the brindled mouse. A clinico-pathological study. J. Neuropathol. Exp. Neurol. 40, 428-46.
15. Nishimura, M. (1989). Animal model for trace metal element deficient disease (particularly, mouse models for Menkes' syndrome) (in Japanese). Med. Immunol. 17, 725-33.
16. Okuda, K., Nasu, K. and Fujisaki, K. (1970). Electron microscopic observations on degenerating photoreceptor synapses of C3H (rodless) mice (in Japanese). Folia Ophthalmol Jpn. 21, 475-82.
17. Panessa, B. J. and Zadunaisky, J. A. (1981). Pigments granules: A calcium reservoir in the vertebrate eye. Exp. Eye Res. 32, 593-604.
18. Samuelson, D. A., Armstrong, D. and Jolly, R. (1990). X-ray microprobe analysis of the retina and RPE in sheep with ovine ceroid lipofuscinosis. Neurobiol. Aging 11, 663-7.
19. Samuelson, D. A., Smith, P., Ulshafer, R. J., Hendricks, D. G., Whitely, R. D., Hendricks, H. and Leone, N. C. (1993). X-ray microanalysis of ocular melanin in pigs maintained on normal and low zinc diets. Exp. Eye Res. 56, 63-70.
20. Takano, K., Mishima, K. and Amemiya, T. (1994). X-ray microanalysis in melanin granules on the retinal pigment epithelium and choroid. Jpn J. Clin. Electron Microsc. (Abstracts) 27 (Supple), 170-1. (In Japanese).
21. Tanaka, K., Kobayashi, K., Fujita, Y., Fukuhara, C., Onosaka, S. and Min, K. (1990). Effects of chelators on copper theory of macular mouse, a model animal of Menkes' kinkey disease. Res. Commun. Chem. Pathol. Pharmacol. 266, 217-27.
22. Tsurui, S. and Sugie, H. (1990). A pathophysiological study of macular mutant mouse as a model of human Menkes' kinkey hair disease. I. Copper contents and copper dependent enzyme activities in various organs (in Japanese). No to Hattatsu 22, 560-5.
23. Ulshafer, R. J., Allen, C. B., and Rubin, M. L. (1990). Distributions of elements in the human retinal pigment epithelium. Arch Ophthalmol. 108, 113-17.
24. Weiss, L. W. and Zelickson, A. S. (1977). Giant melanosomes in multiple lentigines syndrome. Arch. Dermatol. 113, 491-4.
25. Yamano, T., Shimada, M., Onaga, A., Kawasaki, H., Iwane, S., Ono, K. and Nishimura, M. (1988). Electron microscopic study on brain of macular mutant mouse after copper therapy. Acta Neuropathol. 76, 574-80.