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Volumn 90, Issue 1, 1999, Pages 93-100

Wide spectrum of antitumor activity of a neutralizing monoclonal antibody to human vascular endothelial growth factor

Author keywords

Antitumor activity; Monoclonal antibody; Nude mice; VEGF; Xenograft

Indexed keywords

MONOCLONAL ANTIBODY; NEUTRALIZING ANTIBODY; VASCULOTROPIN; VASCULOTROPIN RECEPTOR;

EID: 0033043733     PISSN: 09105050     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1349-7006.1999.tb00671.x     Document Type: Article
Times cited : (63)

References (36)
  • 1
    • 0021978223 scopus 로고
    • Tumor angiogenesis
    • Folkman, J. Tumor angiogenesis. Adv. Cancer Res., 43, 175-203 (1985).
    • (1985) Adv. Cancer Res. , vol.43 , pp. 175-203
    • Folkman, J.1
  • 2
    • 0025141337 scopus 로고
    • What is the evidence that tumors are angiogenesis dependent?
    • Folkman, J. What is the evidence that tumors are angiogenesis dependent? J. Natl. Cancer Inst., 82, 4-6 (1990).
    • (1990) J. Natl. Cancer Inst. , vol.82 , pp. 4-6
    • Folkman, J.1
  • 3
    • 0023157363 scopus 로고
    • Angiogenic factors
    • Folkman, J. and Klagsbrun, M. Angiogenic factors. Science, 235, 442-447 (1987).
    • (1987) Science , vol.235 , pp. 442-447
    • Folkman, J.1    Klagsbrun, M.2
  • 5
    • 0026639806 scopus 로고
    • Angiogenesis
    • Folkman, J. and Shing, Y. Angiogenesis. J. Biol. Chem., 267, 10931-10934 (1992).
    • (1992) J. Biol. Chem. , vol.267 , pp. 10931-10934
    • Folkman, J.1    Shing, Y.2
  • 6
    • 0024818355 scopus 로고
    • Vascular endothelial growth factor is a secreted angiogenic mitogen
    • Leung, D. W., Cachianes, G., Kuang, W.-J., Goeddel, D. V. and Ferrara, N. Vascular endothelial growth factor is a secreted angiogenic mitogen. Science, 246, 1306-1309 (1989).
    • (1989) Science , vol.246 , pp. 1306-1309
    • Leung, D.W.1    Cachianes, G.2    Kuang, W.-J.3    Goeddel, D.V.4    Ferrara, N.5
  • 7
    • 0021111648 scopus 로고
    • Xumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid
    • Senger, D. R., Galli, S. J., Dvorak, A. M. Perruzzi, C. A., Harvey, V. S. and Dvorak, H. F. xumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid. Science, 219, 983-985 (1983).
    • (1983) Science , vol.219 , pp. 983-985
    • Senger, D.R.1    Galli, S.J.2    Dvorak, A.M.3    Perruzzi, C.A.4    Harvey, V.S.5    Dvorak, H.F.6
  • 8
    • 0024816246 scopus 로고
    • Isolation and characterization of a newly identified endothelial cell mitogen produced by AtT-20 cells
    • Plöuet, J., Schilling, J. and Gospodarowicz, D. Isolation and characterization of a newly identified endothelial cell mitogen produced by AtT-20 cells. EMBO J., 8, 3801-3806 (1989).
    • (1989) EMBO J. , vol.8 , pp. 3801-3806
    • Plöuet, J.1    Schilling, J.2    Gospodarowicz, D.3
  • 9
    • 0026446102 scopus 로고
    • Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo
    • Plate, K. H., Breier, G., Weich, H. A. and Risau, W. Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo. Nature, 359, 845-848 (1992).
    • (1992) Nature , vol.359 , pp. 845-848
    • Plate, K.H.1    Breier, G.2    Weich, H.A.3    Risau, W.4
  • 10
    • 0029914374 scopus 로고    scopus 로고
    • Concentration of vascular endothelial growth factor in the serum and tumor tissue of brain tumor patient
    • Takano, S., Yoshii, Y., Kondo, S., Suzuki, H., Maruno, T., Shirai, S. and Nose, T. Concentration of vascular endothelial growth factor in the serum and tumor tissue of brain tumor patient. Cancer Res., 56, 2185-2190 (1996).
    • (1996) Cancer Res. , vol.56 , pp. 2185-2190
    • Takano, S.1    Yoshii, Y.2    Kondo, S.3    Suzuki, H.4    Maruno, T.5    Shirai, S.6    Nose, T.7
  • 11
    • 0028906219 scopus 로고
    • Vascular endothelial growth factor expression and angiogenesis in non-small cell lung carcinomas
    • Mattern, J., Koomagi, R. and Volm, M. Vascular endothelial growth factor expression and angiogenesis in non-small cell lung carcinomas. Int. J. Oncol., 6, 1059-1062 (1995).
    • (1995) Int. J. Oncol. , vol.6 , pp. 1059-1062
    • Mattern, J.1    Koomagi, R.2    Volm, M.3
  • 12
    • 0029143990 scopus 로고
    • Tumor angiogenesis in breast cancer: Its importance as a prognostic indicator and the association with vascular endothelial growth factor expression
    • Toi, M., Inada, K., Suzuki, H. and Tominaga, T. Tumor angiogenesis in breast cancer: its importance as a prognostic indicator and the association with vascular endothelial growth factor expression. Breast Cancer Res. Treat., 36, 193-204 (1995).
    • (1995) Breast Cancer Res. Treat. , vol.36 , pp. 193-204
    • Toi, M.1    Inada, K.2    Suzuki, H.3    Tominaga, T.4
  • 13
    • 84970070220 scopus 로고
    • Expression of vascular endothelial growth factor and its receptor, KDR, correlates with vascularity, metastasis, and proliferation of human colon cancer
    • Takahashi, Y., Kitadai, Y., Bucana, C. D., Cleary, K. R. and Ellis, L. M. Expression of vascular endothelial growth factor and its receptor, KDR, correlates with vascularity, metastasis, and proliferation of human colon cancer. Cancer Res., 55, 3964-3968 (1995).
    • (1995) Cancer Res. , vol.55 , pp. 3964-3968
    • Takahashi, Y.1    Kitadai, Y.2    Bucana, C.D.3    Cleary, K.R.4    Ellis, L.M.5
  • 14
    • 0027933191 scopus 로고
    • Markedly increased amounts of messenger rnas for vascular endothelial growth factor and placenta growth factor in renal cell carcinoma associated with angiogenesis
    • Takahashi, A., Sasaki, H., Kim, S. J., Tobisu, K., Kakizoe, T., Tsukamoto, T., Kumamoto, Y., Sugimura, T. and Terada, M. Markedly increased amounts of messenger RNAs for vascular endothelial growth factor and placenta growth factor in renal cell carcinoma associated with angiogenesis. Cancer Res., 54, 4233-4237 (1994).
    • (1994) Cancer Res. , vol.54 , pp. 4233-4237
    • Takahashi, A.1    Sasaki, H.2    Kim, S.J.3    Tobisu, K.4    Kakizoe, T.5    Tsukamoto, T.6    Kumamoto, Y.7    Sugimura, T.8    Terada, M.9
  • 15
    • 0029155712 scopus 로고
    • Vascular permeability factor (vascular endothelial growth factor) expression and angiogenesis in cervical neoplasia
    • Guidi, A. J., Abu-Jawdeh, G., Berse, B., Jakeman, R. W., Tognazzi, K., Dvorak, H. F. and Brown, L. F. Vascular permeability factor (vascular endothelial growth factor) expression and angiogenesis in cervical neoplasia. J. Natl. Cancer Inst., 87, 1237-1245 (1995).
    • (1995) J. Natl. Cancer Inst. , vol.87 , pp. 1237-1245
    • Guidi, A.J.1    Abu-Jawdeh, G.2    Berse, B.3    Jakeman, R.W.4    Tognazzi, K.5    Dvorak, H.F.6    Brown, L.F.7
  • 18
    • 0027272655 scopus 로고
    • Significance of vascular endothelial growth factor/vascular permeability factor for solid tumor growth, and its inhibition by the antibody
    • Kondo, S., Asano, M. and Suzuki, H. Significance of vascular endothelial growth factor/vascular permeability factor for solid tumor growth, and its inhibition by the antibody. Biochem. Biophys. Res. Commun., 194, 1234-1241 (1993).
    • (1993) Biochem. Biophys. Res. Commun. , vol.194 , pp. 1234-1241
    • Kondo, S.1    Asano, M.2    Suzuki, H.3
  • 19
    • 0028295661 scopus 로고
    • Vascular endothelial growth factor/vascular permeability factor is detectable in the sera of tumor-bearing mice and cancer patients
    • Kondo, S., Asano, M., Matsuo, K., Ohmori, I. and Suzuki, H. Vascular endothelial growth factor/vascular permeability factor is detectable in the sera of tumor-bearing mice and cancer patients. Biochim. Biophys. Acta. 1221, 211-214 (1994).
    • (1994) Biochim. Biophys. Acta. , vol.1221 , pp. 211-214
    • Kondo, S.1    Asano, M.2    Matsuo, K.3    Ohmori, I.4    Suzuki, H.5
  • 24
    • 0031805836 scopus 로고    scopus 로고
    • An anti-human VEGF monoclonal antibody, MV833, that exhibits potent anti-tumor activity in vivo
    • Asano, M., Yukita, A., Matsumoto, H., Hanatani, M. and Suzuki, H. An anti-human VEGF monoclonal antibody, MV833, that exhibits potent anti-tumor activity in vivo. Hybridoma, 17, 185-190 (1998).
    • (1998) Hybridoma , vol.17 , pp. 185-190
    • Asano, M.1    Yukita, A.2    Matsumoto, H.3    Hanatani, M.4    Suzuki, H.5
  • 26
    • 0027197245 scopus 로고
    • Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo
    • Kim, K. J., Li, B., Winer, J., Armanini, M., Gillett, N., Phillips, H. S. and Ferrara, N. Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo. Nature, 362, 841-844 (1993).
    • (1993) Nature , vol.362 , pp. 841-844
    • Kim, K.J.1    Li, B.2    Winer, J.3    Armanini, M.4    Gillett, N.5    Phillips, H.S.6    Ferrara, N.7
  • 27
    • 0026572345 scopus 로고
    • The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor
    • de Vries, C., Escobedo, J. A., Ueno, H., Houck, K., Ferrara, N. and Williams, L. T. The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor. Science, 255, 989-991 (1992).
    • (1992) Science , vol.255 , pp. 989-991
    • De Vries, C.1    Escobedo, J.A.2    Ueno, H.3    Houck, K.4    Ferrara, N.5    Williams, L.T.6
  • 29
    • 0027997863 scopus 로고
    • Different signal transduction properties of KDR and Flt1, two receptors for vascular endothelial growth factor
    • Waltenherger, J., Claesson-Welsh, L., Siegbahn, A., Shibuya, M. and Heldin, C.-H. Different signal transduction properties of KDR and Flt1, two receptors for vascular endothelial growth factor. J. Biol. Chem., 269, 26988-26995 (1994).
    • (1994) J. Biol. Chem. , vol.269 , pp. 26988-26995
    • Waltenherger, J.1    Claesson-Welsh, L.2    Siegbahn, A.3    Shibuya, M.4    Heldin, C.-H.5
  • 30
    • 0027326476 scopus 로고
    • Human melanoma cells but not normal melanocytes express vascular endothelial growth factor receptor
    • Gitay-Goren, H., Halaban, R. and Neufeld, G. Human melanoma cells but not normal melanocytes express vascular endothelial growth factor receptor. Biochem. Biophys. Res. Commun., 190, 702-709 (1993).
    • (1993) Biochem. Biophys. Res. Commun. , vol.190 , pp. 702-709
    • Gitay-Goren, H.1    Halaban, R.2    Neufeld, G.3
  • 31
    • 0028880305 scopus 로고
    • Expression of the vascular endothelial growth factor (VEGF) receptor gene, KDR, in hematopoietic cells and inhibitory effect of VEGF on apoptotic cell death caused by ionizing radiation
    • Katoh, O., Tauchi, H., Kawaishi, K., Kimura, A. and Satow, Y. Expression of the vascular endothelial growth factor (VEGF) receptor gene, KDR, in hematopoietic cells and inhibitory effect of VEGF on apoptotic cell death caused by ionizing radiation. Cancer Res., 55, 5687-5692 (1995).
    • (1995) Cancer Res. , vol.55 , pp. 5687-5692
    • Katoh, O.1    Tauchi, H.2    Kawaishi, K.3    Kimura, A.4    Satow, Y.5
  • 32
    • 0032549799 scopus 로고    scopus 로고
    • Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor
    • Soker, S., Takashima, S., Miao, H. Q., Neufeld, G. and Klagsbrun, M. Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor. Cell, 92, 735-745 (1998).
    • (1998) Cell , vol.92 , pp. 735-745
    • Soker, S.1    Takashima, S.2    Miao, H.Q.3    Neufeld, G.4    Klagsbrun, M.5
  • 33
    • 0028935608 scopus 로고
    • Regulation of vascular endothelial growth factor of human colon cancer tumorigenesis in a mouse model of experimental metastasis
    • Warren, R. S., Yuan, H., Matil, M. R., Gillett, N. A. and Ferrara, N. Regulation of vascular endothelial growth factor of human colon cancer tumorigenesis in a mouse model of experimental metastasis. J. Clin. Invest., 95, 1789-1797 (1995).
    • (1995) J. Clin. Invest. , vol.95 , pp. 1789-1797
    • Warren, R.S.1    Yuan, H.2    Matil, M.R.3    Gillett, N.A.4    Ferrara, N.5
  • 34
    • 0030059075 scopus 로고    scopus 로고
    • Vascular endothelial growth factor promotes tumor dissemination by a mechanism distinct from its effect on primary tumor growth
    • Melnyk, O., Shuman, M. A. and Kim, K. J. Vascular endothelial growth factor promotes tumor dissemination by a mechanism distinct from its effect on primary tumor growth. Cancer Res., 56, 921-924 (1996).
    • (1996) Cancer Res. , vol.56 , pp. 921-924
    • Melnyk, O.1    Shuman, M.A.2    Kim, K.J.3
  • 35
    • 0028174337 scopus 로고
    • Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant
    • Millauer, B., Shawver, L. K., Plate, K. H., Risau, W. and Ullrich, A. Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant. Nature, 367, 576-579 (1994).
    • (1994) Nature , vol.367 , pp. 576-579
    • Millauer, B.1    Shawver, L.K.2    Plate, K.H.3    Risau, W.4    Ullrich, A.5
  • 36


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