Hypothermia prevents biphasic glutamate release and corresponding neuronal degeneration after transient spinal cord ischemia in the rat

Cellular and Molecular Neurobiology

Volumn 19, Issue 2, 1999, Pages 199-208

  Ishikawa, Toshizo ^a   Marsala, Martin ^b  

^a YAMAGUCHI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b University of California   (United States)

Author keywords

Histology; Spinal cord injury; Spinal glutamate release

Indexed keywords

ASPARTIC ACID; DIZOCILPINE; EXCITATORY AMINO ACID; GLUTAMIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

ANIMAL EXPERIMENT; ARGYROPHILIA; ARTICLE; CEREBROSPINAL FLUID ANALYSIS; DATA ANALYSIS; HYPOTHERMIA; MALE; NERVE CELL DEGENERATION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; REPERFUSION; SPINAL CORD ISCHEMIA; STATISTICAL ANALYSIS;

ANIMALIA; LAMIINAE;

EID: 0033043143     PISSN: 02724340     EISSN: None     Source Type: Journal    
DOI: 10.1023/a:1006973026514     Document Type: Article

References (25)

1. Busto, R., Dietrich, W. D., Globus, M. Y., and Ginsberg, M. D. (1989). Postischemic moderate hypothermia inhibits CA1 hippocampal ischemic neuronal injury. Neurosci. Lett. 101:299-304.
2. Choi, D. W., Koh, J. Y., and Peters, S. (1988). Pharmacology of glutamate neurotoxicity in cortical cell culture: Attenuation by NMDA antagonists. J. Neurosci. 8:185-196.
3. Dietrich, W. D., Lin, B., Globus, M. Y., Green, E. J., Ginsberg, E. J., Ginsberg, M. D., and Busto, R. (1995). Effect of delayed MK-801 (Dizocilpine) treatment with or without immediate postischemic hypothermia on chronic neuronal survival after global forebrain ischemia in rats. J. Cereb. Blood Flow Metab. 15:960-968.
4. Ginsberg, M. D., Sternau, L. L., Globus, M. Y., Dietrich, W. D., and Busto, R. (1992). Therapeutic modulation of brain temperature: Relevance to ischemic brain injury. Cerebrovasc. Brain Metab. Rev. 4:189-225.
5. Hao, J. X., Xu, X. J., Aldskogius, H., Seiger, A., and Wiesenfeld-Hallin, Z. (1991). The excitatory amino acid receptor antagonist MK-801 prevents the hypersensitivity induced by spinal cord ischemia in the rat. Exp. Neurol. 113:182-191.
6. Ikunomidou, C., Mosinger, J. L., and Olney, J. W. (1989). Hypothermia enhances protective effect of MK-801 against hypoxic/ischemic brain damage in infant rats. Brain Res. 487:184-187.
7. Kil, H. Y., Zhang, J., and Piantadosi, C. A. (1996). Brain temperature alters hydroxyl radical production during cerebral ischemia/reperfusion in rats. J. Cereb. Blood Flow Metab. 16:100-106.
8. Kramer, R. S., Sanders, A. P., Lesage, A. M., Woodhall, B., and Sealy, W. C. (1968). The effect of profound hypothermia on preservation of cerebral ATP content during circulatory arrest. J. Thorac. Cardiovasc. Surg. 56:699-709.
9. Madden, K. P., Clark, W. M., Kochhar, A., and Zivin, J. A. (1992). Efficacy of LY233053, a competitive glutamate antagonist, in experimental central nervous system ischemia. J. Neurosurg 76:106-110.
10. Marsala, J., Sulla, I., Santa, M., Marsala, M., Mechirova, E., and Jalc, P. (1989). Early neurohistopathological changes of canine lumbosacral spinal cord segments in ischemia-reperfusion-induced paraplegia. Neurosci. Lett. 106:83-88.
11. Marsala, M., Sorkin, L. S., and Yaksh, T. L. (1994). Transient spinal ischemia in rat: Characterization of spinal cord blood flow, extracellular amino acid release, and concurrent histopathological damage. J. Cereb. Blood Flow Metab. 14:604-614.
12. Marsala, M., Melmberg, A., and Yaksh, T. L. (1995). The spinal loop dialysis catheter: Characterization of use in the unanesthetized rat. J. Neurosci. Methods 62:43-53.
13. Marsala, M., Taira, Y., Galik, J., and Yaksh, T. L. (1996). Transient spinal ischemia evokes a biphasic excitatory amino acid and taurine release: A potential role in the development of ischemia induced paraplegia. Soc. Neurosci. Abstr. 22:761.12.
14. Nag, S., and Riopelle, R. J. (1990). Spinal neuronal pathology associated with continuous intrathecal infusion of N-methyl-D-aspartate in the rat. Acta Neuropathol. 81:7-13.
15. Nakashima, K., and Todd, M. M. (1996). Effect of hypothermia on the rate of excitatory amino acid release after ischemic depolarization. Stroke 27:913-918.
16. 3H]MK-801, after intrathecal injection in mice. Pharmacol. Biochem. Behav. 44:9-15.
17. Randall, R. D., and Thayer, S. A. (1992). Glutamate-induced calcium transient triggers delayed calcium overload and neurotoxicity in rat hippocampal neurons. J. Neurosci. 12:1882-1895.
18. Rokkas, C. K., Cronin, C. S., Nitta, T., Helfrich, L. R., Jr., Lobner, D. C., Choi, D. W., and Kouchoukos, N. T. (1995). Profound systemic hypothermia inhibits the release of neurotransmitter amino acids in spinal cord ischemia. J. Thorac. Cardiovasc. Surg. 110:27-35.
19. Rothman, S. M., and Olney, J. W. (1986). Glutamate and the pathophysiology of hypoxic-ischemic brain damage. Ann. Neurol. 19:105-111.
20. Saganova, K., and Marsala, M. (1994). Intrathecal administration of dizocilpine maleate (MK-801) attenuates ischemic damage in the rabbit spinal cord. Exp. Neurol. 130:337-343.
21. Siesjö, B. K., and Bengtsson, F. (1989). Calcium fluxes, calcium antagonists, and calcium-related pathology in brain ischemia, hypoglycemia, and spreading depression: A unifying hypothesis. J. Cereb. Blood Flow Metab. 9:127-140.
22. Simpson, J. I., Eide, T. R., Schiff, G. A., Clagnaz, J. F., Hossain, I., Tverskoy, A., and Koski, G. (1994). Intrathecal magnesium sulfate protects the spinal cord from ischemic injury during thoracic aortic cross-clamping. Anesthesiology 81:1496-1499.
23. Svensson, L. G., Crawford, E. S., Hess, K. R., Coselli, J. S., and Safi, H. J. (1993). Experience with 1509 patients undergoing thoracoabdominal aortic operations. J. Vasc. Surg. 17:357-370.
24. Yaksh, T. L., and Rudy, T. A. (1976). Chronic catheterization of the spinal subarachnoid space. Physiol. Behav. 17:1031-1036.
25. Yum, S. W., and Faden, A. I. (1990). Comparison of the neuroprotective effects of the N-methyl-D-aspartate antagonist MK-801 and the opiate-receptor antagonist nalmefene in experimental spinal cord ischemia. Arch. Neurol. 47:277-281.