Design of immuno-enzymosomes with maximum enzyme targeting capability: Effect of the enzyme density on the enzyme targeting capability and cell binding properties

Biochimica et Biophysica Acta - Biomembranes

Volumn 1419, Issue 2, 1999, Pages 272-282

  Fonseca, M J ^a   Haisma, H J ^b   Klaassen, S ^a   Vingerhoeds, M H ^a   Storm, G ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

^b VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

ADEPT; Antibody directed enzyme prodrug therapy; Cell binding; Enzyme targeting; Liposome

Indexed keywords

ANTINEOPLASTIC AGENT; BETA GLUCURONIDASE; ENZYME; IMMUNOLIPOSOME; LIPOSOME; PRODRUG;

ANTIBODY DIRECTED ENZYME PRODRUG THERAPY; ARTICLE; CANCER CELL; CELL ADHESION; CONTROLLED STUDY; DRUG TARGETING; ENZYME ACTIVITY; ENZYME PURIFICATION; FEMALE; HUMAN; HUMAN CELL; OVARY CANCER; PRIORITY JOURNAL;

ANTIBODIES, MONOCLONAL; ANTIBODIES, NEOPLASM; ANTINEOPLASTIC AGENTS; CELL ADHESION; DRUG CARRIERS; DRUG DESIGN; ENZYMES; GLUCURONIDASE; IMMUNOGLOBULIN FAB FRAGMENTS; LIPOSOMES; MEMBRANE GLYCOPROTEINS; TUMOR CELLS, CULTURED;

EID: 0033042189     PISSN: 00052736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0005-2736(99)00073-5     Document Type: Article

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