Clinicopathologic features and genetic alterations in endometrioid carcinoma of the uterus with villoglandular differentiation

American Journal of Clinical Pathology

Volumn 111, Issue 3, 1999, Pages 336-342

  Esteller, Manel ^a,c   Garcia, Angel ^a   Martinez Palones, Josep M ^a   Xercavins, Jordi ^a   Reventes, Jaume ^a,b  

^a HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

^b HOSPITAL MATERNO INFANTIL VALL D HEBRON   (Spain)

^c JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

c erbB2 neu; CYP1A1; Endometrial carcinoma; Genetic alterations; Inherited susceptibility; K ras; Methylenetetrahydrofolate reductase; MTHFR; p53; Villoglandular carcinoma

Indexed keywords

ARTICLE; CANCER STAGING; CLINICAL FEATURE; ENDOMETRIUM CARCINOMA; FEMALE; GENETIC LINKAGE; GENOTYPE; HUMAN; HUMAN TISSUE; ONCOGENE K RAS; ONSET AGE; PRIORITY JOURNAL; PROGNOSIS; RECEPTOR DENSITY;

EID: 0033041183     PISSN: 00029173     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajcp/111.3.336     Document Type: Article

References (32)

1. Parker SI, Tong T, Bolden S, et al. Cancer statistics, 1996. CA Cancer J Clin. 1996;46:27.
2. Parazzini F, La Vecchia C, Bocciolone L, et al. The epidemiology of endometrial cancer. Gynecol Oncol. 1991;41:1-16.
3. Gurpide E. Endometrial cancer: biochemical and clinical correlates. J Natl Cancer Inst. 1991;20:405-416.
4. Kurman RJ, Zaino RJ, Norris HJ. Endometrial carcinoma. In: Kurman RJ, ed. Blaustein's Pathology of the Female Genital Tract. New York, NY: Springer-Verlag; 1994:439-486.
5. Park RC, Grigsby PW, Muss HB, et al. Corpus: epithelial tumors. In: Hoskins WJ, Perez CA, Toung RC, eds. Principles and Practice of Gynecologic Oncology. Philadelphia, Pa: Lippincott; 1992:663-693.
6. Hendrickson M, Ross J, Eifel P, et al. Uterine papillary serous carcinoma: a highly malignant form of endometrial carcinoma. Am J Surg Pathol. 1982;6:93-108.
7. Carcangiu ML, Chambers JT. Uterine papillary serous carcinoma: a study of 108 cases with emphasis on the prognostic significance of associated endometrioid carcinoma, absence of invasion, and concomitant ovarian carcinoma. Gynecol Oncol. 1992;47:298-305.
8. Goff BA, Kato D, Schmidt RA, et al. Uterine papillary serous carcinoma: patterns of metastatic spread. Gynecol Oncol. 1994;54:264-268.
9. Cher JL, Trost DC, Wilkinson EJ. Endometrial papillary adenocarcinomas: two clinicopathological types. Int J Gynecol Pathol. 1985;4:279-288.
10. O'Hanlan KA, Levine PA, Harbatkin D, et al. Virulence of papillary endometrial carcinoma. Gynecol Oncol. 1990;37:112-119.
11. Symonds DA. Prognostic value of pathologic features and DNA analysis in endometrial carcinoma. Gynecol Oncol. 1990;39:272-276.
12. Ambros RA, Ballouk F, Malfetano JH, et al. Significance of papillary (villoglandular) differentiation in endometrioid carcinoma of the uterus. Am J Surg Pathol. 1994;18:569-575.
13. Berchuck A, Boyd J. Molecular basis of endometrial cancer. Cancer. 1995;76:2034-2040.
14. Boyd J. Molecular biology in the clinicopathologic assessment of endometrial carcinoma subtypes. Gynecol Oncol. 1996;61:163-165.
15. Esteller M, Garcia A, Martinez-Palones JM, et al. Detection of c-erbB2/neu and fibroblast growth factor-3/INT-2 but not epidermal growth factor receptor gene amplification by differential polymerase chain reaction. Cancer. 1995;75:2139-2146.
16. Wright DK, Manos MM. Sample preparation from paraffin-embedded tissues. In: Innis MA, Gelfand DH, Sninsky JJ, et al, eds. PCR Protocols: A Guide to Methods and Applications. New York, NY: Harcourt Brace Jovanovich; 1990:153-166.
17. Esteller M, Garcia A, Martinez-Palones JM, et al. Detection of clonality and genetic alterations in endometrial pipelle biopsy and its surgical specimen counterpart. Lab Invest. 1997;76:109-116.
18. Jiang W, Kahn SM, Guillem JG, et al. Rapid detection of ras oncogenes in human tumors: applications to colon, esophageal and gastric cancer. Oncogene. 1989;4:923-928.
19. Frye RA, Benz CC, Liu E. Detection of amplified oncogenes by differential polymerase chain reaction. Oncogene. 1989;4:1153-1157.
20. Lazar V, Hazard F, Bertin F, et al. Simple sequence repeat polymorphism within the p53 gene. Oncogene. 1993;8:1703-1705.
21. Esteller M, Garcia A, Martinez-Palones JM, et al. Susceptibility to endometrial cancer: influence of allelism at p53, glutathione S-transferase (GSTM1 and GSTT1) and cytochrome P-450 loci. Br J Cancer. 1997;75:1385-1388.
22. De la Calle-Martin O, Fabregat V, Romero M, et al. AccII polymorphism of the p53 gene. Nucleic Acids Res. 1990;18:463.
23. Hayashi S, Watanabe J, Nakachi K, et al. Genetic linkage of lung cancer-associated MspI polymorphisms with amino acid replacement in the heme binding region of the human cytochrome P4501A1 gene. J Biochem. 1991;110:407-411.
24. Cascorbi I, Brockmoller J, Roots I. A C4887A polymorphism in exon 7 of human CYP1A1: population frequency, mutation linkages, and impact on lung cancer susceptibility. Cancer Res. 1996;56:4965-4969.
25. Chen J, Giovanucci E, Kelsey K, et al. A methylenetetrahydrofolate reductase polymorphism and the risk of colorectal cancer. Cancer Res. 1996;56:4862-4864.
26. Shields PG, Bowman ED, Harrington AM, et al. Polycyclic aromatic hydrocarbon-DNA adducts in human lung and cancer susceptibility genes. Cancer Res. 1993;53:3486-3492.
27. Mikuta JJ. FIGO staging of endometrial cancer: 1988. Cancer. 1993;71:1460-1463.
28. Rose PG. Endometrial carcinoma. N Engl J Med. 1996;335:640-649.
29. Christopherson WM, Connelly PJ, Alberhasky RC. Carcinoma of the endometrium, V: an analysis of prognosticators in patients with favorable subtypes and stage I disease. Cancer. 1983;51:1705-1709.
30. Prat J, Oliva E, Lerma E, et al. Uterine papillary serous adenocarcinoma: a 10-case study of p53 and c-erbB-2 expression and DNA content. Cancer. 1994;74:1778-1783.
31. Esteller M, Garcia A, Martinez-Palones JM, et al. The clinicopathological significance of K-ras point mutation and gene amplification in endometrial cancer. Eur J Cancer. 1997;33:1572-1577.
32. Mizuuchi H, Nasrim S, Kudo R, et al. Clinical implications of K-ras mutations in malignant epithelial tumors of the endometrium. Cancer Res. 1992;52:2777-2781.