메뉴 건너뛰기




Volumn 115, Issue 3, 1999, Pages 526-533

Alzheimer's β-amyloid peptides can activate the early components of complement classical pathway in a C1q-independent manner

Author keywords

amyloid peptide; C1q; Complement; Contact system

Indexed keywords

AMYLOID BETA PROTEIN; BLOOD CLOTTING FACTOR 12; COMPLEMENT COMPONENT C1; COMPLEMENT COMPONENT C1Q; COMPLEMENT COMPONENT C4;

EID: 0033041151     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.1999.00835.x     Document Type: Article
Times cited : (35)

References (42)
  • 1
    • 0028123071 scopus 로고
    • Alzheimer's disease: A central role of amyloid
    • Selkoe DJ. Alzheimer's disease: a central role of amyloid. J Neuropathol Exp Neurol 1994; 53:438-47.
    • (1994) J Neuropathol Exp Neurol , vol.53 , pp. 438-447
    • Selkoe, D.J.1
  • 2
    • 0030250615 scopus 로고    scopus 로고
    • β-Amyloid converts an acute phase injury response to chronic injury response
    • Cotman CW, Tenner AJ, Cummings BJ. β-Amyloid converts an acute phase injury response to chronic injury response. Neurobiol Aging 1996; 17:723-31.
    • (1996) Neurobiol Aging , vol.17 , pp. 723-731
    • Cotman, C.W.1    Tenner, A.J.2    Cummings, B.J.3
  • 3
    • 0027104778 scopus 로고
    • Full complement activation fails in diffuse plaques of Alzheimer's disease cerebellum
    • Lue LF, Rogers J. Full complement activation fails in diffuse plaques of Alzheimer's disease cerebellum. Dementia 1992; 3:308-13.
    • (1992) Dementia , vol.3 , pp. 308-313
    • Lue, L.F.1    Rogers, J.2
  • 4
    • 0030250826 scopus 로고    scopus 로고
    • Inflammatory mechanisms in neurodegeneration and Alzheimer's disease: The role of the complement system
    • Pasinetti GM. Inflammatory mechanisms in neurodegeneration and Alzheimer's disease: the role of the complement system. Neurobiol Aging 1996; 17:707-16.
    • (1996) Neurobiol Aging , vol.17 , pp. 707-716
    • Pasinetti, G.M.1
  • 5
    • 0028217539 scopus 로고
    • Ultrastructural localization of complement membrane attack complex (MAC)-like immunoreactivity in brains of patients with Alzheimer's disease
    • Itagaki S, Akiyama H, Saito H et al. Ultrastructural localization of complement membrane attack complex (MAC)-like immunoreactivity in brains of patients with Alzheimer's disease. Brain Res 1994; 645:78-84.
    • (1994) Brain Res , vol.645 , pp. 78-84
    • Itagaki, S.1    Akiyama, H.2    Saito, H.3
  • 6
    • 0029655992 scopus 로고    scopus 로고
    • Early complement components in Alzheimer's disease brain
    • Veerhuis R, Janssen J, Hack CE et al. Early complement components in Alzheimer's disease brain. Acta Neuropathol 1996; 91:53-60.
    • (1996) Acta Neuropathol , vol.91 , pp. 53-60
    • Veerhuis, R.1    Janssen, J.2    Hack, C.E.3
  • 7
    • 0028169558 scopus 로고
    • Decreased levels of Clq in cerebrospinal fluid of living Alzheimer's patients correlate with disease state
    • Smith MD, Cribbs DH, Tenner AJ et al. Decreased levels of Clq in cerebrospinal fluid of living Alzheimer's patients correlate with disease state. Neurobiol Aging 1994; 15:609-14.
    • (1994) Neurobiol Aging , vol.15 , pp. 609-614
    • Smith, M.D.1    Cribbs, D.H.2    Tenner, A.J.3
  • 8
    • 0026447529 scopus 로고
    • Complement activation by β-amyloid in Alzheimer's disease
    • Rogers J, Cooper NR, Webster S et al. Complement activation by β-amyloid in Alzheimer's disease. Proc Natl Acad Sci USA 1992; 89:10016-20.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 10016-10020
    • Rogers, J.1    Cooper, N.R.2    Webster, S.3
  • 9
    • 0028178458 scopus 로고
    • β-Amyloid activates complement by binding to a specific region of the collagen-like domain of the Clq A chain
    • Jiang H, Burdick D, Glabe CG et al. β-Amyloid activates complement by binding to a specific region of the collagen-like domain of the Clq A chain. J Immunol 1994; 152:5050-9.
    • (1994) J Immunol , vol.152 , pp. 5050-5059
    • Jiang, H.1    Burdick, D.2    Glabe, C.G.3
  • 10
    • 0031031747 scopus 로고    scopus 로고
    • Aspartate residue 7 in amyloid β-protein is critical for classical complement pathway activation: Implication for Alzheimer's disease pathogenesis
    • Velazquez P, Cribbs DH, Poulos TL et al. Aspartate residue 7 in amyloid β-protein is critical for classical complement pathway activation: implication for Alzheimer's disease pathogenesis. Nature Med 1997; 3:77-79.
    • (1997) Nature Med , vol.3 , pp. 77-79
    • Velazquez, P.1    Cribbs, D.H.2    Poulos, T.L.3
  • 11
    • 0030918418 scopus 로고    scopus 로고
    • Aggregation state-dependent activation of the classical complement pathway by the amyloid-β peptide
    • Webster S, Bradt B, Rogers J et al. Aggregation state-dependent activation of the classical complement pathway by the amyloid-β peptide. J Neurochem 1997; 69:388-98.
    • (1997) J Neurochem , vol.69 , pp. 388-398
    • Webster, S.1    Bradt, B.2    Rogers, J.3
  • 12
    • 0027966134 scopus 로고
    • Complement Clq does not bind monomeric β-Amyloid
    • Snyder SW, Wang GT, Barret L et al. Complement Clq does not bind monomeric β-Amyloid. Exp Neurol 1994; 128:136-42.
    • (1994) Exp Neurol , vol.128 , pp. 136-142
    • Snyder, S.W.1    Wang, G.T.2    Barret, L.3
  • 13
    • 0030250758 scopus 로고    scopus 로고
    • Neuroglial-mediated immunoinflammatory response in Alzheimer's disease: Complement activation and therapeutic approaches
    • Chen S, Frederickson RCA, Brunden KR. Neuroglial-mediated immunoinflammatory response in Alzheimer's disease: complement activation and therapeutic approaches. Neurobiol Aging 1996; 17:781-7.
    • (1996) Neurobiol Aging , vol.17 , pp. 781-787
    • Chen, S.1    Frederickson, R.C.A.2    Brunden, K.R.3
  • 14
    • 0030885721 scopus 로고    scopus 로고
    • The intrinsic coagulation/kinin-forming cascade: Assembly in plasma and cell surfaces in inflammation
    • Kaplan AP, Joseph K, Shibayama Y et al. The intrinsic coagulation/kinin-forming cascade: assembly in plasma and cell surfaces in inflammation. Adv Immunol 1997; 66:225-73.
    • (1997) Adv Immunol , vol.66 , pp. 225-273
    • Kaplan, A.P.1    Joseph, K.2    Shibayama, Y.3
  • 15
    • 0014055995 scopus 로고
    • The conversion of C'ls to C'l esterase by plasmin and trypsin
    • Ratnoff OD, Naff GB. The conversion of C'ls to C'l esterase by plasmin and trypsin. J Exp Med 1967; 125:337-58.
    • (1967) J Exp Med , vol.125 , pp. 337-358
    • Ratnoff, O.D.1    Naff, G.B.2
  • 16
    • 0028657575 scopus 로고
    • Activation of complement and kinin systems after thrombolytic therapy in patients with acute myocardial infarction. A comparison between streptokinase and recombinant tissue-type plasminogen activator
    • Agostoni A, Gardinali M, Frangi D et al. Activation of complement and kinin systems after thrombolytic therapy in patients with acute myocardial infarction. A comparison between streptokinase and recombinant tissue-type plasminogen activator. Circulation 1994; 90:2666-70.
    • (1994) Circulation , vol.90 , pp. 2666-2670
    • Agostoni, A.1    Gardinali, M.2    Frangi, D.3
  • 17
    • 0028169154 scopus 로고
    • Hageman factor and its binding sites are present in senile plaques of Alzheimer disease
    • Yasuhara O, Walker DG, McGeer PL. Hageman factor and its binding sites are present in senile plaques of Alzheimer disease. Brain Res 1994; 654:234-40.
    • (1994) Brain Res , vol.654 , pp. 234-240
    • Yasuhara, O.1    Walker, D.G.2    McGeer, P.L.3
  • 18
    • 0032450703 scopus 로고    scopus 로고
    • Activation of the contact system in cerebro-spinal fluid of patients with Alzheimer's disease
    • Bergamaschini L, Parnetti L, Pareyson D et al. Activation of the contact system in cerebro-spinal fluid of patients with Alzheimer's disease. Alzh Dis Assoc Dis 1998; 12:102-8.
    • (1998) Alzh Dis Assoc Dis , vol.12 , pp. 102-108
    • Bergamaschini, L.1    Parnetti, L.2    Pareyson, D.3
  • 19
    • 0028928084 scopus 로고
    • In vitro stimulation of tissue-type plasminogen activator by Alzheimer amyloid β-peptide analogues
    • Kingston IB, Castro MJM, Anderson S. In vitro stimulation of tissue-type plasminogen activator by Alzheimer amyloid β-peptide analogues. Nature Med 1995; 1:138-42.
    • (1995) Nature Med , vol.1 , pp. 138-142
    • Kingston, I.B.1    Castro, M.J.M.2    Anderson, S.3
  • 20
    • 0023134627 scopus 로고
    • Immunoblotting studies of coagulation Factor XII, plasma prekallikrein and high molecular weight kininogen
    • Lammle B, Berrettini M, Griffin JH. Immunoblotting studies of coagulation Factor XII, plasma prekallikrein and high molecular weight kininogen. Sem Throm Hemost 1987; 13:106-14.
    • (1987) Sem Throm Hemost , vol.13 , pp. 106-114
    • Lammle, B.1    Berrettini, M.2    Griffin, J.H.3
  • 21
    • 0022543615 scopus 로고
    • Detection of in vivo cleavage of high molecular weight kininogen in human plasma by immunoblotting with monoclonal antibodies
    • Berrettini M, Lammle B, White T et al. Detection of in vivo cleavage of high molecular weight kininogen in human plasma by immunoblotting with monoclonal antibodies. Blood 1986; 68:455-62.
    • (1986) Blood , vol.68 , pp. 455-462
    • Berrettini, M.1    Lammle, B.2    White, T.3
  • 22
    • 0019750662 scopus 로고
    • Inactivation of trypsin-like enzymes with peptides of arginine chlorometyl ketone
    • Kettner C, Shaw E. Inactivation of trypsin-like enzymes with peptides of arginine chlorometyl ketone. Methods Enzymol 1981; 80:826-42.
    • (1981) Methods Enzymol , vol.80 , pp. 826-842
    • Kettner, C.1    Shaw, E.2
  • 23
    • 0020472522 scopus 로고
    • Kinetics of the activation of plasminogen by human tissue plasminogen activator
    • Hoylaerts M, Rijken DC, Lijnen HR et al. Kinetics of the activation of plasminogen by human tissue plasminogen activator. J Biol Chem 1982; 257:2912-9.
    • (1982) J Biol Chem , vol.257 , pp. 2912-2919
    • Hoylaerts, M.1    Rijken, D.C.2    Lijnen, H.R.3
  • 24
    • 0022476922 scopus 로고
    • Kinetics of interaction of Cl inhibitor with Cls
    • Lennick M, Brew SA, Ingham KC. Kinetics of interaction of Cl inhibitor with Cls. Biochemestry 1986; 25:3890-8.
    • (1986) Biochemestry , vol.25 , pp. 3890-3898
    • Lennick, M.1    Brew, S.A.2    Ingham, K.C.3
  • 25
    • 0020529790 scopus 로고
    • Mechanism of activation of the classical pathway of complement by Hageman factor fragment
    • Ghebrehiwet B, Randazzo BP, Dunn JT et al. Mechanism of activation of the classical pathway of complement by Hageman factor fragment. J Clin Invest 1983; 71:1450-6.
    • (1983) J Clin Invest , vol.71 , pp. 1450-1456
    • Ghebrehiwet, B.1    Randazzo, B.P.2    Dunn, J.T.3
  • 26
    • 0019471542 scopus 로고
    • Activation of the classical pathway of complement by Hageman factor fragment
    • Ghebreiwet B, Silverberg M, Kaplan AP. Activation of the classical pathway of complement by Hageman factor fragment. J Exp Med 1981; 153:665-76.
    • (1981) J Exp Med , vol.153 , pp. 665-676
    • Ghebreiwet, B.1    Silverberg, M.2    Kaplan, A.P.3
  • 27
    • 0029671451 scopus 로고    scopus 로고
    • Water-soluble Aβ (N-40, N-42) oligomers in normal and Alzheimer disease brains
    • Kuo Y-M, Emmerling ME, Vigo-Pelfrey C et al. Water-soluble Aβ (N-40, N-42) oligomers in normal and Alzheimer disease brains. J Biol Chem 1996; 271:4077-81.
    • (1996) J Biol Chem , vol.271 , pp. 4077-4081
    • Kuo, Y.-M.1    Emmerling, M.E.2    Vigo-Pelfrey, C.3
  • 28
    • 0028168336 scopus 로고
    • Amyloid-β aggregation: Selective inhibition of aggregation in mixtures of amyloid with different chain lengths
    • Snyder SW, Ladror US, Wade WS et al. Amyloid-β aggregation: selective inhibition of aggregation in mixtures of amyloid with different chain lengths. Biophys J 1994; 67:1216-28.
    • (1994) Biophys J , vol.67 , pp. 1216-1228
    • Snyder, S.W.1    Ladror, U.S.2    Wade, W.S.3
  • 29
    • 0026595567 scopus 로고
    • Assembly-and aggregation properties of synthetic Alzheimer's A4/β amyloid peptide analogs
    • Burdick D, Soreghan B, Kwon M et al. Assembly-and aggregation properties of synthetic Alzheimer's A4/β amyloid peptide analogs. J Biol Chem 1992; 267:546-54.
    • (1992) J Biol Chem , vol.267 , pp. 546-554
    • Burdick, D.1    Soreghan, B.2    Kwon, M.3
  • 30
    • 0028135459 scopus 로고
    • Enhanced aggregation and β structure of amyloid β-peptide after coincubation with Clq
    • Webster S, O'Barr S, Rogers J. Enhanced aggregation and β structure of amyloid β-peptide after coincubation with Clq. J Neurosci Res 1994; 39:448-56.
    • (1994) J Neurosci Res , vol.39 , pp. 448-456
    • Webster, S.1    O'Barr, S.2    Rogers, J.3
  • 31
    • 0026523080 scopus 로고
    • Microglia isolated from rat brain secrete a urokinase-type plasminogen activator
    • Nakajima K, Tsuzaki N, Takemoto N et al. Microglia isolated from rat brain secrete a urokinase-type plasminogen activator. Brain Res 1992; 577:285-92.
    • (1992) Brain Res , vol.577 , pp. 285-292
    • Nakajima, K.1    Tsuzaki, N.2    Takemoto, N.3
  • 32
    • 0026703642 scopus 로고
    • Production and secretion of plasminogen in cultured rat brain microglia
    • Nakajima K, Tsuzaki N, Shimojo M et al. Production and secretion of plasminogen in cultured rat brain microglia. FEBS Letters 1992; 308:179-82.
    • (1992) FEBS Letters , vol.308 , pp. 179-182
    • Nakajima, K.1    Tsuzaki, N.2    Shimojo, M.3
  • 33
    • 0028360524 scopus 로고
    • Expression and cellular localization of messenger RNA for plasminogen activator inhibitor type I in human astrocytomas in vivo
    • Yamamoto M, Sawaya R, Mohanam S et al. Expression and cellular localization of messenger RNA for plasminogen activator inhibitor type I in human astrocytomas in vivo. Cancer Res 1994; 54:3329-32.
    • (1994) Cancer Res , vol.54 , pp. 3329-3332
    • Yamamoto, M.1    Sawaya, R.2    Mohanam, S.3
  • 34
    • 0028918713 scopus 로고
    • Complement Cl-inhibitor is produced by brain and is cleaved in Alzheimer's disease
    • Walker DG, Yasuhara O, Patston PA et al. Complement Cl-inhibitor is produced by brain and is cleaved in Alzheimer's disease. Brain Res 1995; 675:75-82.
    • (1995) Brain Res , vol.675 , pp. 75-82
    • Walker, D.G.1    Yasuhara, O.2    Patston, P.A.3
  • 35
    • 0013577969 scopus 로고
    • Action of polyionic substances on the complement system
    • Sim B, ed. Dordrecht: Kluwer Academic Publishers
    • von Zabern I. Action of polyionic substances on the complement system. In: Sim B, ed. Activators and inhibitor's of complement. Dordrecht: Kluwer Academic Publishers, 1983:149-65.
    • (1983) Activators and Inhibitor's of Complement , pp. 149-165
    • Von Zabern, I.1
  • 36
    • 0018969588 scopus 로고
    • A newly described control mechanism of complement activation in patients with mixed cryoglobulinemia
    • Haydey RP, Patarroyo de Royas M, Gigli I. A newly described control mechanism of complement activation in patients with mixed cryoglobulinemia. J Invest Dermatol 1980; 74:328-32.
    • (1980) J Invest Dermatol , vol.74 , pp. 328-332
    • Haydey, R.P.1    Patarroyo de Royas, M.2    Gigli, I.3
  • 37
    • 0014466084 scopus 로고
    • The inhibition of plasmin, plasma kallikrein, plasma permeability factor, and the Clr subcomponent of the first component of complement by serum Cl esterase inhibitor
    • Ratnoff OD, Pensky J, Ogston D et al. The inhibition of plasmin, plasma kallikrein, plasma permeability factor, and the Clr subcomponent of the first component of complement by serum Cl esterase inhibitor. J Exp Med 1969;129:315-71.
    • (1969) J Exp Med , vol.129 , pp. 315-371
    • Ratnoff, O.D.1    Pensky, J.2    Ogston, D.3
  • 38
    • 0021241859 scopus 로고
    • Inactivation of Factor XII active fragment in normal plasma. Predominant role of Cl-inhibitor
    • de Agostini A, Lijnen HR, Pixley RA et al. Inactivation of Factor XII active fragment in normal plasma. Predominant role of Cl-inhibitor. J Clin Invest 1984; 73:1542-9.
    • (1984) J Clin Invest , vol.73 , pp. 1542-1549
    • De Agostini, A.1    Lijnen, H.R.2    Pixley, R.A.3
  • 39
    • 0018196283 scopus 로고
    • Modulation of the antigenicity of Cls and Clr by Cl inactivator
    • Ziccardi RJ, Cooper NR. Modulation of the antigenicity of Cls and Clr by Cl inactivator. J Immunol 1978; 121:2148-52.
    • (1978) J Immunol , vol.121 , pp. 2148-2152
    • Ziccardi, R.J.1    Cooper, N.R.2
  • 40
    • 0031691401 scopus 로고    scopus 로고
    • Complement Cl-inhibitor expression in Alzheimer's disease
    • Veerhuis R, Ianssen I, Hoozemans JJM et al. Complement Cl-inhibitor expression in Alzheimer's disease. Acta Neuropathol 1998; 96:287-96.
    • (1998) Acta Neuropathol , vol.96 , pp. 287-296
    • Veerhuis, R.1    Ianssen, I.2    Hoozemans, J.J.M.3
  • 41
    • 9444245809 scopus 로고    scopus 로고
    • Morphology and toxicity of Aβ-(1-42) dimer derived from neuritic and vascular amyloid deposits of Alzheimer's disease
    • Roher AE, Chaney MO, Kuo Y-M et al. Morphology and toxicity of Aβ-(1-42) dimer derived from neuritic and vascular amyloid deposits of Alzheimer's disease. J Biol Chem 1996; 271:20631-5.
    • (1996) J Biol Chem , vol.271 , pp. 20631-20635
    • Roher, A.E.1    Chaney, M.O.2    Kuo, Y.-M.3
  • 42
    • 0029670094 scopus 로고    scopus 로고
    • β-Amyloid-mediated vasoactivity and vascular endothelial damage
    • Thomas T, Thomas G, McLendon C. β-Amyloid-mediated vasoactivity and vascular endothelial damage. Nature 1996; 380: 168-71.
    • (1996) Nature , vol.380 , pp. 168-171
    • Thomas, T.1    Thomas, G.2    McLendon, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.