Abnormal expression of the cystic fibrosis transmembrane regulator in chronic sinusitis in cystic fibrosis and non-cystic fibrosis patients

Annals of Otology, Rhinology and Laryngology

Volumn 108, Issue 6, 1999, Pages 576-581

  Coltrera, Marc D ^a   Goodpaster, Tracy A ^a   Mathison, Susan M ^a   Gown, Allen M ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Cystic fibrosis; Cystic fibrosis transmembrane regulator; Immunocytochemistry; Sinusitis

Indexed keywords

MONOCLONAL ANTIBODY; TOSYLARGININE METHYL ESTER; TRANSMEMBRANE CONDUCTANCE REGULATOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL MEMBRANE; CHRONIC SINUSITIS; CONTROLLED STUDY; CYSTIC FIBROSIS; CYTOPLASM; GENE MUTATION; IMMUNOCYTOCHEMISTRY; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL;

EID: 0033040777     PISSN: 00034894     EISSN: None     Source Type: Journal    
DOI: 10.1177/000348949910800609     Document Type: Article

References (36)

1. Aitken ML, Fiel SB. Cystic fibrosis. Dis Mon 1993;39: 1-52.
2. Riordan JR, Rommens JM, Kerem B, et al. Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA. Science 1989;245:1066-73.
3. Kerem B, Rommens JM, Buchanan JA, et al. Identification of the cystic fibrosis gene: genetic analysis. Science 1989; 245:1073-80.
4. Rommens JM, Iannuzzi MC, Kerem B, et al. Identification of the cystic fibrosis gene: chromosome walking and jumping. Science 1989;245:1059-65.
5. Crawford I, Maloney PC, Zeitlin PL, et al. Immunocytochemical localization of the cystic fibrosis gene product CFTR. Proc Natl Acad Sci U S A 1991;88:9262-6.
6. Denning GM, Ostedgaard LS, Cheng SH, Smith AE, Welsh MJ. Localization of cystic fibrosis transmembrane conductance regulator in chloride secretory epithelia. J Clin Invest 1992;89:339-49.
7. Engelhardt JF, Yankaskas JR, Ernst SA, et al. Submucosal glands are the predominant site of CFTR expression in the human bronchus. Nat Genet 1992;2:240-8.
8. Puchelle E, Gaillard D, Ploton D, et al. Differential localization of the cystic fibrosis transmembrane conductance regulator in normal and cystic fibrosis airway epithelium. Am J Respir Cell Mol Biol 1992;7:485-91.
9. Cheng SH, Gregory RJ, Marshall J, et al. Defective intracellular transport and processing of CFTR is the molecular basis of most cystic fibrosis. Cell 1990;63:827-34.
10. Gown AM, Vogel AM. Monoclonal antibodies to intermediate filament proteins of human cells: unique and crossreacting antibodies. J Cell Biol 1982;95:414-24.
11. Sarkadi B, Bauzon D, Huckle WR, et al. Biochemical characterization of the cystic fibrosis transmembrane conductance regulator in normal and cystic fibrosis epithelial cells. J Biol Chem 1992;267:2087-95.
12. Tran-Paterson R, Davin D, Krauss RD, Rado TA, Miller DM. Expression and regulation of the cystic fibrosis gene during rat liver regeneration. Am J Physiol 1992;263:C55-C60.
13. Schoumacher RA, Ram J, Iannuzzi MC, et al. A cystic fibrosis pancreatic adenocarcinoma cell line. Proc Natl Acad Sci U S A 1990;87:4012-6.
14. Coltrera MD, Wang J, Porter PL, Gown AM. Expression of platelet-derived growth factor B-chain and the platelet-derived growth factor receptor beta subunit in human breast tissue and breast carcinoma. Cancer Res 1995;55:2703-8.
15. Marino CR, Matovcik LM, Gorelick FS, Cohn JA. Localization of the cystic fibrosis transmembrane conductance regulator in pancreas. J Clin Invest 1991;88:712-6.
16. Walker J, Watson J, Holmes C, Edelman A, Banting G. Production and characterisation of monoclonal and polyclonal antibodies to different regions of the cystic fibrosis transmembrane conductance regulator (CFTR): detection of immunologically related proteins. J Cell Sci 1995;108:2433-44.
17. Brezillon S, Dupuit F, Hinnrasky J, et al. Decreased expression of the CFTR protein in remodeled human nasal epithelium from non-cystic fibrosis patients. Lab Invest 1995;72:191-200.
18. Cohn JA, Melhus O, Page LJ, Dittrich KL, Vigna SR. CFTR: development of high-affinity antibodies and localization in sweat gland. Biochem Biophys Res Commun 1991;181: 36-43.
19. Kartner N, Augustinas O, Jensen TJ, Naismith AL, Riordan JR. Mislocalization of delta F508 CFTR in cystic fibrosis sweat gland. Nat Genet 1992;1:321-7.
20. Ramsey B, Richardson MA. Impact of sinusitis in cystic fibrosis. J Allergy Clin Immunol 1992;90:547-52.
21. Nishioka GJ, Cook PR. Paranasal sinus disease in patients with cystic fibrosis. Otolaryngol Clin North Am 1996;29: 193-205.
22. Batsakis JG, El-Naggar AK. Cystic fibrosis and the sinonasal tract. Ann Otol Rhinol Laryngol 1996;105:329-30.
23. Quinton PM. Abnormalities in electrolyte secretion in cystic fibrosis sweat glands due to decreased anion permeability. In: Quinton PM, Martinez RJ, Hopfer U, eds. Fluid and electrolyte abnormalities in exocrine glands in cystic fibrosis. San Francisco, Calif: San Francisco Press, 1982:53-76.
24. Smit LS, Strong TV, Wilkinson DJ, et al. Missense mutation (G480C) in the CFTR gene associated with protein mislocalization but normal chloride channel activity. Hum Mol Genet 1995;4:269-73.
25. Salva PS, Doyle NA, Graham L, Eigen H, Doerschuk CM. TNF-alpha, IL-8, soluble ICAM-1, and neutrophils in sputum of cystic fibrosis patients. Pediatr Pulmonol 1996;21:11-9.
26. Davidsson A, Danielsen A, Viale G, et al. Positive identification in situ of mRNA expression of IL-6, and IL-12, and the chemotactic cytokine RANTES in patients with chronic sinusitis and polypoid disease. Clinical relevance and relation to allergy. Acta Otolaryngol (Stockh) 1996;116:604-10.
27. Pfeffer KD, Huecksteadt TP, Hoidal JR. Expression and regulation of tumor necrosis factor in macrophages from cystic fibrosis patients. Am J Respir Cell Mol Biol 1993;9:511-9.
28. Takeuchi K, Yuta A, Sakakura Y. Interleukin-8 gene expression in chronic sinusitis. Am J Otolaryngol 1995;16:98-102.
29. Hamilos DL, Leung DY, Wood R, et al. Eosinophil infiltration in nonallergic chronic hyperplastic sinusitis with nasal polyposis (CHS/NP) is associated with endothelial VCAM-1 upregulation and expression of TNF-alpha. Am J Respir Cell Mol Biol 1996;15:443-50.
30. Lund VJ, Henderson B, Song Y. Involvement of cytokines and vascular adhesion receptors in the pathology of fronto-ethmoidal mucocoeles. Acta Otolaryngol (Stockh) 1993;113:540-6.
31. Richman E-J. Cytokine soup: making sense of inflammation in cystic fibrosis. Pediatr Pulmonol 1996;21:3-5.
32. Besancon F, Przewlocki G, Baró I, Hongre AS, Escande D, Edelman A. Interferon-gamma downregulates CFTR gene expression in epithelial cells. Am J Physiol 1994;267:C1398-C1404.
33. Zund G, Madara JL, Dzus AL, Awtrey CS, Colgan SP. Interleukin-4 and interleukin-13 differentially regulate epithelial chloride secretion. J Biol Chem 1996;271:7460-4.
34. Dupuit F, Kalin N, Brézillon S, Hinnrasky J, Tummler B, Puchelle E. CFTR and differentiation markers expression in non-CF and delta F 508 homozygous CF nasal epithelium. J Clin Invest 1995;96:1601-11.
35. Barasch J, Kiss B, Prince A, Saiman L, Gruenert D, Al-Awqati Q. Defective acidification of intracellular organelles in cystic fibrosis. Nature 1991;352:70-3.
36. Jacquot J, Puchelle E, Hinnrasky J, et al. Localization of the cystic fibrosis transmembrane conductance regulator in airway secretory glands. Eur Respir J 1993;6:169-76.