Microinjection of mitochondria into zygotes creates a model for studying the inheritance of mitochondrial DNA during preimplantation development

Fertility and Sterility

Volumn 71, Issue 5, 1999, Pages 912-918

  Rinaudo, Paolo ^a   Niven Fairchild, Tracy ^a   Buradagunta, Syam ^a   Massobrio, Marco ^a   Revelli, Alberto ^a   Keefe, David L ^b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WOMEN AND INFANTS HOSPITAL   (United States)

Author keywords

Embryo development; MELAS; Microinjection; Mitochondria; mtDNA; Preimplantation

Indexed keywords

MITOCHONDRIAL DNA;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DNA DETERMINATION; EMBRYO; EMBRYO DEVELOPMENT; FEMALE; GENE MUTATION; HUMAN; HUMAN CELL; INHERITANCE; MICROINJECTION; MITOCHONDRION; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PREIMPLANTATION EMBRYO; PRIORITY JOURNAL; ZYGOTE;

ANIMALS; DNA PRIMERS; DNA, MITOCHONDRIAL; EMBRYONIC DEVELOPMENT; FEMALE; MICE; MICE, INBRED STRAINS; MICROINJECTIONS; MUTATION; POLYMERASE CHAIN REACTION; PREGNANCY; ZYGOTE;

EID: 0033040727     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0015-0282(99)00089-8     Document Type: Article

References (25)

1. Kao S., Chao H.T., Wei J.H. Mitochondrial deoxyribonucleic acid 4977-bb selection is associated with diminished fertility and motility of human sperm. Biol Reprod. 52:1995;729-736.
2. Keefe D.L., Niven-Fairchild T., Powell S., Buradagunta S. Mitochondrial deoxyribonucleic acid deletions in oocytes and reproductive aging in women. Fertil Steril. 64:1995;577-583.
3. Laipis P.J., Van de Walle M.J., Hauswirth W. Unequal partitioning of bovine mitochondrial genotypes among siblings. Proc Natl Acad Sci USA. 85:1988;8107-8111.
4. Sutovsky P., Navara C.S., Schatten G. Fate of the sperm mitochondria, and the incorporation, conversion, and disassembly of the sperm tail structures during bovine fertilization. Biol Reprod. 55:1996;1195-1205.
5. Piko L., Matsumoto L. Number of mitochondria and some properties of mitochondrial DNA in the mouse egg. Dev Biol. 49:1976;1-10.
6. Gyllensten U., Wharton D., Josefsson A., Wilson A.C. Paternal inheritance of mitochondrial DNA in mice. Nature. 352:1991;255-257.
7. Bibb M.J., Van Etten R.A., Wright C.T., Walberg M.W., Clayton D.A. Sequence and gene organization of mouse mitochondrial DNA. Cell. 26:1981;167-180.
8. Larsson N.G., Clayton D.A. Molecular genetic aspects of human mitochondrial disorders. Annu Rev Genet. 29:1995;151-178.
9. Yoneda M., Chomyn A., Martinuzzi A., Hurko O., Attardi G. Marked replicative advantage of human mtDNA carrying a point mutation that causes the MELAS encephalomyopathy. Proc Natl Acad Sci USA. 89:1992;11164-11168.
10. Isaya G., Fenton W.A., Hendrick J.P., Furtak K., Kalousek F., Rosenberg L.E. Mitochondrial impact and processing of mutant human oznithine transcarbamylase processors in cultured cells. Mol Cell Biol. 8:1988;5150-5158.
11. Hunter M.J., Commerford S.L. Pressure homogenization of mammalian tissue. Biochim Biophys Acta. 47:1961;580-586.
12. Moraes C.T., Ricci E., Bonilla E., DiMauro S., Schon E.A. The mitochondrial tRNA (Leu(UUR)) mutation in mitochondrial encephalomyopathy, lactic acidosis, and stroke-like syndrome (MELAS) genetic, biochemical, and morphological correlation in skeletal muscle . Am J Hum Genet. 50:1992;934-949.
13. Mehlmann L.M., Kline D. Regulation of intracellular calcium in the mouse egg calcium release in response to sperm or inositol triphosphate is enhanced after meiotic maturation . Biol Reprod. 51:1994;1088-1098.
14. Cooperstein S.J., Lazarow A. A microspectrophotometric method for the determination of cytochrome C oxidase. J Biol Chem. 86:1950;129-139.
15. Harman D. The biologic clock the mitochondria? J Am Geriatr Soc. 1972;145-147.
16. Corbisier P., Remacle J. Involvement of mitochondria in cell degeneration. J Cell Biol. 51:1988;173-182.
17. Hayashi J.H., Yonekawa H., Gotoh O., Watanabe J., Tagashira Y. Strictly maternal inheritance of rat mitochondrial DNA. Biochem Biophys Res Commun. 83:1978;1032-1038.
18. Giles R.E., Blanc H., Cann H.M., Wallace D.C. Maternal inheritance of human mitochondrial DNA. Proc Natl Acad Sci USA. 77:1980;6715-6719.
19. Kaneda H., Hayashi J.H., Takahama S., Taya S., Fisher Lindhal K., Yonekawa H. Elimination of paternal mitochondria in intraspecific crosses during early mouse embryogenesis. Proc Natl Acad Sci USA. 92:1994;4542-4546.
20. Kondo R., Satta Y., Matsuura E.T., Ishiwa H., Takahata N., Chigusa S.L. Incomplete maternal transmission of mitochondrial DNA in Drosophila. Genetics. 126:1990;657-663.
21. Zouros E., Oberhauser Ball A., Saavedra C., Freeman K.R. An unusual type of mitochondrial DNA inheritance in the blue mussel Mytilus. Proc Natl Acad Sci USA. 91:1994;7463-7467.
22. DeFrancesco L., Attardi G., Croce C.M. Uniparental propagation of mitochondrial DNA in mouse-human cell hybrids. Proc Natl Acad Sci USA. 77:1980;4079-4083.
23. King M.P., Attardi G. Injection of mitochondrial DNA into human cells leads to a rapid replacement of the endogenous mitochondrial DNA. Cell. 52:1988;811-819.
24. Ebert K.M., Alcivar A., Liem H., Goggins R., Hecht N.B. Mouse zygotes injected with mitochondria develop normally but the exogenous mitochondria are not detectable in the progeny. Mol Reprod Dev. 1:1989;156-163.
25. Cascio S.M., Wassarman P.M. Program of early development in the mammal synthesis of mitochondrial proteins during oogenesis and early embryogenesis in the mouse . Dev Biol. 83:1981;166-172.