The influence of highly active antiretroviral therapy on AIDS- associated Kaposi's sarcoma

British Journal of Dermatology

Volumn 140, Issue 5, 1999, Pages 875-881

  Dupin, Nicolas ^a,b,d   Rubin De Cervens, V ^a   Gorin, I ^a   Calvez, V ^b   Pessis, E ^a   Grandadam, M ^b   Rabian, C ^c   Viard, J P ^c   Huraux, J M ^b   Escande, J P ^a  

^a Institut Cochin   (France)

^b PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^c HÔPITAL NECKER ENFANTS MALADES   (France)

^d INSTITUTE OF CANCER RESEARCH   (United Kingdom)

Author keywords

AIDS associated Kaposi's sarcoma; CD4 count; Combination antiretroviral therapy

Indexed keywords

ALPHA INTERFERON; ANTIRETROVIRUS AGENT; BLEOMYCIN; CHORIONIC GONADOTROPIN BETA SUBUNIT; DAUNORUBICIN; DOXORUBICIN; INDINAVIR; LAMIVUDINE; ROQUINIMEX; STAVUDINE; VINCRISTINE; VIRUS RNA; ZIDOVUDINE;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ADULT; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; COMBINATION CHEMOTHERAPY; HELPER CELL; HUMAN; HUMAN HERPESVIRUS 8; HUMAN IMMUNODEFICIENCY VIRUS 1; IMMUNOTHERAPY; KAPOSI SARCOMA; LUNG SARCOMA; LYMPHOCYTE COUNT; PRIORITY JOURNAL; VIREMIA;

ACQUIRED IMMUNODEFICIENCY SYNDROME; ADULT; CD4 LYMPHOCYTE COUNT; DRUG THERAPY, COMBINATION; HERPESVIRUS 8, HUMAN; HIV PROTEASE INHIBITORS; HIV-1; HUMANS; LUNG NEOPLASMS; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; RNA, VIRAL; SARCOMA, KAPOSI; SKIN NEOPLASMS; STATISTICS, NONPARAMETRIC; SURVIVAL RATE; TREATMENT OUTCOME; VIREMIA;

EID: 0033040041     PISSN: 00070963     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2133.1999.02818.x     Document Type: Article

References (14)

1. Hammer SM, Squires KE, Hughes MD et al. A controlled trial of two nucleoside analogues plus indinavir in persons with human immunodeliciency virus infection and CD4 cell counts of 200 per cubic millimeter or less. N Engl J Med 1997; 337: 725-33.
2. Gulick RM, Mellors JW, Havlir D et al. Treatment with indinavir. zidovudine, and lamivudine in adults with human immunodeficiency virus Infection and prior antiretroviral therapy. N Engl J Med 1997; 337: 734-9.
3. Chang Y, Cesarman E, Pessin MS et al. Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma. Science 1994; 266: 1865-9.
4. Dupin N, Grandadam M, Calvez V et al. Herpesvirus-like DNA sequences in patients with Mediterranean Kaposi's sarcoma. Lancet 1995; 345: 761-2.
5. Lebbé C, de Crémoux P, Ryhojad M, Costa da Cunha C, Morel P, Calvo F. Kaposi's sarcoma and new herpesvirus. Lancet 1995; 345: 1180.
6. Whithby D, Howard MR, Tenant-Flowers M et al. Detection of Kaposi sarcoma associated herpesvirus in peripheral blood of HIV-infected individuals and progression to Kaposi's sarcoma. Lancet 1995; 346: 799-802.
7. Moore PS, Kingsley LA, Holmberg SD et al. Kaposi's sarcoma-associated herpesvirus infection prior to onset of Kaposi's sarcoma. AIDS 1996; 10: 175-80.
8. Lebbe C. Agbalika F, De Crémoux P et al. Detection of human herpesvirus 8 and human T-cell lymphotropic virus type 1 sequences in Kaposi sarcoma. Arch Dermatol 1997; 133: 25-30.
9. Krown SE, Metrocka C, Wernz JC. Kaposi's sarcoma in the acquired immune deficiency syndrome: a proposal for uniform evaluation, response and staying criteria. J Clin Oncol 1989; 7: 1201-7.
10. Dupin N, Franck N, Calvez V et al. Lack of evidence of human herpesvirus 8 DNA sequences in HIV-negative patients with various lymphoproliferalive disorders of the skin. Br J Dermatol 1997; 136: 827-30.
11. Naidich DP, Tarras M, Garay SM et al. Kaposi's sarcoma: CT-radiographic correlation. Chest 1989; 96: 723-8.
12. Lebbé C, Blum L, Pellet C et al. Clinical and biological impact of antiretroviral therapy with protease inhibitors on HIV-related Kaposi's sarcoma. AIDS 1998; 12: F45-9.
13. Lock MJ, Griffiths PD, Emery VC. Development of a quantitative competitive polymerase chain reaction for human herpesvirus 8. J Virol Methods 1997; 64: 19-26.
14. Grandadam M, Dupin N, Galvez V et al. Exacerbations of clinical symptoms in human immunodeficiency virus type-I infected patients with multicentric Castleman's disease are associated with a high increase in Kaposi's sarcoma herpesvirus DNA load in peripheral blood mononuclear cells. J Infect Dis 1997; 175: 1198-201.