Development of low cost peptide-based anti-hepatitis C virus screening and confirmatory assays: Comparison with commercially available tests

Journal of Medical Virology

Volumn 58, Issue 3, 1999, Pages 221-226

  Palacios, Alejandro ^a   Taylor, Lizeth ^a   Haue, Lizbeth ^a   Luftig, Ronald B ^b   Visoná, Kirsten A ^a,c  

^a Louisiana Stt Univ Intl Ctr M   (Costa Rica)

^b Lion's Eye Research Laboratories   (United States)

^c Jet Box Miami   (United States)

Author keywords

Anti HCV; Blood donors; Screening confirmation; Synthetic peptides

Indexed keywords

SYNTHETIC PEPTIDE; VIRUS ANTIBODY;

ANTIBODY DETECTION; ARTICLE; BLOOD DONOR; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST; DIAGNOSTIC VALUE; ELECTROIMMUNOASSAY; HEPATITIS C; HEPATITIS C VIRUS; HUMAN; INFECTION RISK; MAJOR CLINICAL STUDY; NONHUMAN; SCREENING TEST; VIRUS DETECTION;

AMINO ACID SEQUENCE; BLOOD DONORS; COSTS AND COST ANALYSIS; DEVELOPING COUNTRIES; HEPACIVIRUS; HEPATITIS C; HEPATITIS C ANTIBODIES; HUMANS; MASS SCREENING; MOLECULAR SEQUENCE DATA; OLIGOPEPTIDES; REAGENT KITS, DIAGNOSTIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, VIRAL; SENSITIVITY AND SPECIFICITY;

EID: 0033039256     PISSN: 01466615     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9071(199907)58:3<221::AID-JMV6>3.0.CO;2-S     Document Type: Article

References (34)

1. Aach RD, Stevens CE, Hollinger FB, Mosley JW, Peterson DA, Taylor PE, Johnson RG, Barbosa LH, Nemo GJ. 1991. Hepatitis C virus infection in post-transfusion hepatitis. N Engl J Med 325:1325-1329.
2. Allain JP, Rankin A, Kuhns MC, McNamara A. 1992. Clinical importance of HCV confirmatory testing in blood donors. Lancet 339: 1171-1172.
3. Alter HJ. 1994. Transmission patterns in hepatitis C virus infection. In: Nishioka K, Suzuki H, Mishiro S, Oda T, editors. Viral hepatitis and liver disease. New York: Springer-Verlag, p 445-449.
4. Alter HJ, Seeff LB. 1993. Transfusion-associated hepatitis. In: Zuckerman THC, editor. Viral hepatitis. Scientific basis and clinical management. New York: Churchill Livingstone. p 467-500.
5. Alter HJ, Purcell RM, Shih JW, Melpolder JC, Houghton M, Choo Q-L, Kuo G. 1989. Detection of antibody to hepatitis C virus in prospectively followed transfusion recipients with acute and chronic non-A, non-B hepatitis. N Engl J Med 321;1494-1500.
6. Attia MAM, Abdel-Rahman NZ, Goudsmit J, Boom R, Khaled HM, Mansour MT, de WoIf F, Alam El-Din HM, Sol CJA. 1996. Diverse patterns of recognition of hepatitis C virus core and nonstructural antigens by antibodies present in Egyptian cancer patients and blood donors. J Clin Microbiol 34:2665-2669
7. Barrera JM, Bruguera M, González M, Gálvez A, Castillo R, Rodés J. 1996. Eficacia de la exclusion de donantes anti-VHC positive por ELISA 2 en la preventión de la hepatitis postransfusional. Gastroenterol Hepatol 19:240-242.
8. Bresters D, Zaauer HL, Cuypers HTM, et al. 1993. Recombinant immunoblot assay reaction patterns and hepatitis C virus RNA in blood donors and non-A, non-B hepatitis patients. Transfusion 33: 634-638.
9. Brown G, Powell L, Morris A, Rassam S, Sherlock S, McIntyre N, Zuckerman AJ, Dusheiko GM. 1992. Improved diagnosis of chronic hepatitis C virus infection by detection of antibody to multiple epitopes: confirmation by antibody to synthetic oligopeptides. J Med Virol 38:167-171.
10. Cerino A, Bissolati M, Cividini A, Nicosia A, Esumi M, Hayashi N, Mizuno K, Slobbe R, Oudshoorn P, Silini E, Asti M, Mondelli MU. 1997. Antibody response to the hepatitis C virus E2 protein: relationship to viremia and prevalence in anti-HCV seronegative subjects. J Med Virol 51:1-5.
11. Chaudhary RK, Jacobsen H. 1994. Performance of third-generation confirmatory tests for detection of antibody to hepatitis C virus. J Clin Microbiol 32:2606-2608.
12. Claeys H, Volckerts A, Mertens W, Liang Z, Fiten P, Opdenakker G. 1995. Localization and reactivity of an immunodominant domain in the NS3 region of hepatitis C virus. J Med Virol 45:273-281.
13. Davidson F, Prescott LE, Yap PL, Simmonds P. 1996. Relevance of RIBA-3 supplementary test to HCV PCR positivity and genotypes for HCV confirmation of blood donors. J Med Virol 49:132-136.
14. Dhillon AP, Dusheiko GM. 1995. Pathology of hepatitis C virus infection. Histopathology 26:297-309.
15. Dow BC, Buchanan I, Munro H, Follett EAC, Davidson F, Prescott LE, Yap PL, Simmonds P. 1996. Relevance of RIBA-3 supplementary test to HCV PCR positivity and genotypes for HCV confirmation of blood donors. J Med Virol 49:132-136.
16. Dussaix E, Charnaux N, Laurent-Puig P, Chopineau S, Laurian Y, Buffet C. 1994. Analysis of sera indeterminate by Ortho-HCV RIBA-2 by using three confirmatory assays for anti-hepatitis C virus antibody. J Clin Microbiol 32:2071-2075.
17. Esteban JI. 1995. Diagnostic tests in HCV infection. HCV infection: epidemiology, diagnosis, and treatment. Suppl. monograph. Dallas: Medical Communications Resources, Inc. chap 2.
18. García Z, Taylor L, Ruano A, Pavón L, Ayerdis E, Luftig RB, Visoná KA. 1996. Evaluation of a pooling method for routine anti-HCV screening of blood donors to lower the cost burden on blood banks in countries under development. J Med Virol 49:218-222.
19. Garson J, Tuke P, Makris M, Briggs M, Machin S, Preston F, Tedder R. 1990. Demonstration of viremia patterns in haemophiliacs treated with hepatitis C-virus contaminated factor VIII concentrates. Lancet 336:1022-1025.
20. Ishida Ch, Matsumoto K, Fukada K, Matsushita K, Shiraki H, Maeda Y. 1993. Detection of antibodies to hepatitis C virus (HCV) structural proteins in anti-HCV-positive sera by an enzyme-linked immunosorbent assay using synthetic peptides as antigens. J Clin Microbiol 31:936-940.
21. Katayama T, Mazda T, Kikuchi S, Harada S, Matsuura Y, Chiba J, Ohba H, Saito I, Miyamura T. 1992. Improved serodiagnosis of non-A, non-B hepatitis by an assay detecting antibody to hepatitis C virus core antigen. Hepatology 5:431-435.
22. Khudyakov YE, Khudyakova NS, Jue DL, Lambert SB, Fang S, Fields HA. 1995. Linear B-cell epitopes of the NS3-NS4-NS5 proteins of the hepatitis C virus as modeled with synthetic peptides. Virology 206:666-672.
23. Kleinman S, Alter H, Busch M, Holland P, Tegtmeier G, Nelles M, Lee S, Page E, Wilber J, Palito A. 1992. Increased detection of hepatitis C virus (HCV)-infected blood donors by a multiple antigen HCV enzyme immunoassay. Transfusion (Philadelphia) 32:806-813.
24. Kotwal GJ, Baroudy BM, Kuramoto IK, Mcdonald FF, Schiff GM, Holland PV, Zeldis JB. 1992. Detection of acute hepatitis C virus infection by ELISA using a synthetic peptide comprising a structural epitope. Proc Natl Acad Sci USA 89:4486-4489.
25. Kuo G, Choo QL, Alter HJ, Gitnik GL, Redeker AG, Purcell RH, Miyamura T, Dienstag JL, Alter MJ, Stevens CE, Tegtmeier GE, Bonino F, Colombo M, Lee W-S, Kuo C, Berger K, Shuster JR, Overby LR, Bradley DW, Houghton M. 1989. An assay for circulating antibodies to a major etiologic virus of human non-A, non-B hepatitis. Science 244:362-364.
26. Lee DS, Lesniewski RR, Sung YC, et al. 1996. Significance of anti-E2 in the diagnosis of HCV infection in patients on maintenance hemodialysis: anti-E2 is frequently detected among anti-HCV antibody-negative patients. J Am Soc Nephrol 7:2409-2413.
27. Lok A, Gunaratnam NT. 1997. NIH diagnosis of hepatitis C conference, Bethesda, MD. March 24-26. p 1-5.
28. Marin MG, Bresciani S, Puoti M, Rodella A, Gussago A, Ravaggi A, Pizzocolo G, Albertini A, Cariani E. 1994. Clinical significance of serum hepatitis C virus (HCV) RNA as marker of HCV infection. J Clin Microbiol 32:3008-3012.
29. National Institutes of Health (NIH). 1997. NIH consensus statement. Management of hepatitis C, Bethesda, MD, March 24-26. vol 15. p 1-41.
30. Okamoto HT, Machida A, Munekata E, Akahane Y, Sugai Y, Mashiko K, Mitsui T, Tanaka T, Miyakawa Y, Mayumi M. 1992. Antibodies against synthetic oligopeptides deduced from the putative core gene for the diagnosis of hepatitis C virus infection. Hepatology 15:180-186.
31. Pan American Health Organization (PAHO), 1997. Situation of the blood banks in the region of the Americas, 1994-1995. PAHO Epidemiol Bull 18:11-12.
32. Sällberg M, Rudén U, Wahren B, Magnius LO. 1992. Immunodominant regions within the hepatitis C virus core and putative matrix proteins. J Clin Microbiol 30:1989-1994.
33. Tibbs CJ, Palmer SJ, Coker R, Clark SK, Parsons GM, Hojvat S, Peterson D, Banatvala JE. 1991. Prevalence of hepatitis C in tropical communities: the importance of confirmatory assays. J Med Virol 34:143-147.
34. Vernelen K, Clayes H, Verhaert A, Volckaerets A, Vemylen C. 1994. Significance of NS3 and NS5 antigens in screening for HCV anti-bodies. Lancet 343:853.