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Volumn 9, Issue 1, 1999, Pages 81-88

Establishing links between developmental signaling pathways and cell-cycle regulation in Drosophila

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL TISSUE; CELL CYCLE; CELL DIVISION; CELL FATE; DEVELOPMENT; DEVELOPMENTAL GENETICS; DROSOPHILA; EMBRYO; MORPHOGENESIS; NONHUMAN; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION;

EID: 0033039013     PISSN: 0959437X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-437X(99)80012-4     Document Type: Article
Times cited : (14)

References (64)
  • 1
    • 0029837986 scopus 로고    scopus 로고
    • Developmental control of cell cycle regulators: A fly's perspective
    • Edgar BA, Lehner CF Developmental control of cell cycle regulators: a fly's perspective. Science. 274:1996;1646-1652.
    • (1996) Science , vol.274 , pp. 1646-1652
    • Edgar, B.A.1    Lehner, C.F.2
  • 3
    • 0030951678 scopus 로고    scopus 로고
    • Cell cycle regulators in Drosophila: Downstream and part of developmental decisions
    • Lehner CF, Lane ME Cell cycle regulators in Drosophila: downstream and part of developmental decisions. J Cell Sci. 110:1997;523-528.
    • (1997) J Cell Sci , vol.110 , pp. 523-528
    • Lehner, C.F.1    Lane, M.E.2
  • 4
    • 0030692745 scopus 로고    scopus 로고
    • Controlling cell proliferation in differentiating tissues: Genetic analysis of negative regulators of G1→S-phase progression
    • Zavitz KH, Zipursky SL Controlling cell proliferation in differentiating tissues: genetic analysis of negative regulators of G1→S-phase progression. Curr Opin Cell Biol. 9:1997;773-781.
    • (1997) Curr Opin Cell Biol , vol.9 , pp. 773-781
    • Zavitz, K.H.1    Zipursky, S.L.2
  • 5
    • 0031047711 scopus 로고    scopus 로고
    • Stopping and starting the meiotic cell cycle
    • Page AW, Orr-Weaver TL Stopping and starting the meiotic cell cycle. Curr Opin Genet Dev. 7:1997;23-31.
    • (1997) Curr Opin Genet Dev , vol.7 , pp. 23-31
    • Page, A.W.1    Orr-Weaver, T.L.2
  • 6
    • 0030892233 scopus 로고    scopus 로고
    • Connecting cell behavior to patterning: Lessons from the cell cycle
    • Follette PJ, O'Farrell PH Connecting cell behavior to patterning: lessons from the cell cycle. Cell. 88:1997;309-314.
    • (1997) Cell , vol.88 , pp. 309-314
    • Follette, P.J.1    O'Farrell, P.H.2
  • 7
    • 0024464666 scopus 로고
    • Mitotic domains reveal early commitment of cells in Drosophila embryos
    • Foe VE Mitotic domains reveal early commitment of cells in Drosophila embryos. Development. 107:1989;1-22.
    • (1989) Development , vol.107 , pp. 1-22
    • Foe, V.E.1
  • 8
    • 0030747044 scopus 로고    scopus 로고
    • Drosophila mitotic domain boundaries as cell fate boundaries
    • A photoactivatable transcription factor is used to induce lacZ gene expression in single cells prior to gastrulation of Drosophila embryos. The location of the activated cell and its daughters was then determined in late-stage embryos. The data support the conclusion that the borders between groups of cells which divide synchronously in the early embryo (mitotic domains) represent cell-fate boundaries.
    • Cambridge SB, Davis RL, Minden JS Drosophila mitotic domain boundaries as cell fate boundaries. Science. 277:1997;825-828. A photoactivatable transcription factor is used to induce lacZ gene expression in single cells prior to gastrulation of Drosophila embryos. The location of the activated cell and its daughters was then determined in late-stage embryos. The data support the conclusion that the borders between groups of cells which divide synchronously in the early embryo (mitotic domains) represent cell-fate boundaries.
    • (1997) Science , vol.277 , pp. 825-828
    • Cambridge, S.B.1    Davis, R.L.2    Minden, J.S.3
  • 9
    • 0028109854 scopus 로고
    • Transcriptional regulation of string (cdc25): A link between developmental programming and the cell cycle
    • Edgar BA, Lehman DA, O'Farrell PH Transcriptional regulation of string (cdc25): a link between developmental programming and the cell cycle. Development. 120:1994;3131-3143.
    • (1994) Development , vol.120 , pp. 3131-3143
    • Edgar, B.A.1    Lehman, D.A.2    O'Farrell, P.H.3
  • 10
    • 0031193397 scopus 로고    scopus 로고
    • S-phase function of Drosophila cyclin A and its downregulation in G1 phase
    • Sprenger F, Yakubovich N, O'Farrell PH S-phase function of Drosophila cyclin A and its downregulation in G1 phase. Curr Biol. 7:1997;488-499.
    • (1997) Curr Biol , vol.7 , pp. 488-499
    • Sprenger, F.1    Yakubovich, N.2    O'Farrell, P.H.3
  • 11
    • 0029013865 scopus 로고
    • Distinct modes of cyclin E/cdc2c kinase regulation and S-phase control in mitotic and endoreduplication cycles of Drosophila embryogenesis
    • Sauer K, Knoblich JA, Richardson H, Lehner CF Distinct modes of cyclin E/cdc2c kinase regulation and S-phase control in mitotic and endoreduplication cycles of Drosophila embryogenesis. Genes Dev. 9:1995;1327-1339.
    • (1995) Genes Dev , vol.9 , pp. 1327-1339
    • Sauer, K.1    Knoblich, J.A.2    Richardson, H.3    Lehner, C.F.4
  • 12
    • 0028358931 scopus 로고
    • Cyclin E controls S phase progression and its down-regulation during Drosophila embryogenesis is required for the arrest of cell proliferation
    • Knoblich JA, Sauer K, Jones L, Richardson H, Saint R, Lehner CF Cyclin E controls S phase progression and its down-regulation during Drosophila embryogenesis is required for the arrest of cell proliferation. Cell. 77:1994;107-120.
    • (1994) Cell , vol.77 , pp. 107-120
    • Knoblich, J.A.1    Sauer, K.2    Jones, L.3    Richardson, H.4    Saint, R.5    Lehner, C.F.6
  • 13
    • 0009677457 scopus 로고    scopus 로고
    • Chromosome association of minichromosome maintenance proteins in Drosophila endoreplication cycles
    • In situ antibody staining is used to characterize the association of dMCM2 with salivary gland polytene chromosomes before and after overexpression of cyclin E. Together with data from [14], the authors suggest that one way cyclin E/cdk2 might stimulate S phase is to promote association of MCM proteins with DNA (e.g. as part of a pre-replicative complex assembly at origins of DNA replication.)
    • Su TT, O'Farrell PH Chromosome association of minichromosome maintenance proteins in Drosophila endoreplication cycles. J Cell Biol. 140:1998;451-460. In situ antibody staining is used to characterize the association of dMCM2 with salivary gland polytene chromosomes before and after overexpression of cyclin E. Together with data from [14], the authors suggest that one way cyclin E/cdk2 might stimulate S phase is to promote association of MCM proteins with DNA (e.g. as part of a pre-replicative complex assembly at origins of DNA replication.).
    • (1998) J Cell Biol , vol.140 , pp. 451-460
    • Su, T.T.1    O'Farrell, P.H.2
  • 14
    • 0003143219 scopus 로고    scopus 로고
    • Chromosome association of minichromosome maintenance proteins in Drosophila mitotic cycles
    • Su TT, O'Farrell PH Chromosome association of minichromosome maintenance proteins in Drosophila mitotic cycles. J Cell Biol. 139:1997;13-21.
    • (1997) J Cell Biol , vol.139 , pp. 13-21
    • Su, T.T.1    O'Farrell, P.H.2
  • 15
    • 0029802648 scopus 로고    scopus 로고
    • The Drosophila endocycle is controlled by Cyclin E and lacks a checkpoint ensuring S-phase completion
    • Lilly MA, Spradling AC The Drosophila endocycle is controlled by Cyclin E and lacks a checkpoint ensuring S-phase completion. Genes Dev. 10:1996;2514-2526.
    • (1996) Genes Dev , vol.10 , pp. 2514-2526
    • Lilly, M.A.1    Spradling, A.C.2
  • 16
    • 0030796226 scopus 로고    scopus 로고
    • Mutations in Drosophila DP and E2F distinguish G1-S progression from an associated transcriptional program
    • Royzman I, Whittaker AJ, Orr-Weaver TL Mutations in Drosophila DP and E2F distinguish G1-S progression from an associated transcriptional program. Genes Dev. 11:1997;1999-2011.
    • (1997) Genes Dev , vol.11 , pp. 1999-2011
    • Royzman, I.1    Whittaker, A.J.2    Orr-Weaver, T.L.3
  • 17
    • 0031972699 scopus 로고    scopus 로고
    • Mutations of the Drosophila dDP, dE2F, and cyclin E genes reveal distinct roles for the E2F-DP transcription factor and cyclin E during the G1-S transition
    • Differences in the pattern of BrdU incorporation after genetic reduction of dE2F/dDP function or cyclin E function are characterized in embryonic endocycles. The data suggest that cyclin E provides a molecular threshold for triggering S phase in an 'all or none' fashion.
    • Duronio RJ, Bonnette PC, O'Farrell PH Mutations of the Drosophila dDP, dE2F, and cyclin E genes reveal distinct roles for the E2F-DP transcription factor and cyclin E during the G1-S transition. Mol Cell Biol. 18:1998;141-151. Differences in the pattern of BrdU incorporation after genetic reduction of dE2F/dDP function or cyclin E function are characterized in embryonic endocycles. The data suggest that cyclin E provides a molecular threshold for triggering S phase in an 'all or none' fashion.
    • (1998) Mol Cell Biol , vol.18 , pp. 141-151
    • Duronio, R.J.1    Bonnette, P.C.2    O'Farrell, P.H.3
  • 18
    • 0032510035 scopus 로고    scopus 로고
    • Continuous Cyclin E expression inhibits progression through endoreduplication cycles in Drosophila
    • •] demonstrates that overexpression of cyclin E in endoreduplicating tissue inhibits DNA synthesis. This suggests that downregulation of cyclin E/cdk2 kinase is required to re-establish replication competence in an endocycle. As cyclin E is also required for S phase, a cycle of activation and deactivation of cyclin E/cdk2 forms the basis of the endocycle (see also [15] and [40]).
    • •] demonstrates that overexpression of cyclin E in endoreduplicating tissue inhibits DNA synthesis. This suggests that downregulation of cyclin E/cdk2 kinase is required to re-establish replication competence in an endocycle. As cyclin E is also required for S phase, a cycle of activation and deactivation of cyclin E/cdk2 forms the basis of the endocycle (see also [15] and [40]).
    • (1998) Curr Biol , vol.8 , pp. 239-242
    • Weiss, A.1    Herzig, A.2    Jacobs, H.3    Lehner, C.F.4
  • 21
    • 0030904445 scopus 로고    scopus 로고
    • A role for Cdk2 kinase in negatively regulating DNA replication during S phase of the cell cycle
    • Hua XH, Yan H, Newport J A role for Cdk2 kinase in negatively regulating DNA replication during S phase of the cell cycle. J Cell Biol. 137:1997;183-192.
    • (1997) J Cell Biol , vol.137 , pp. 183-192
    • Hua, X.H.1    Yan, H.2    Newport, J.3
  • 23
    • 0031106334 scopus 로고    scopus 로고
    • Limb morphogenesis: Connections between patterning and growth
    • Serrano N, O'Farrell PH Limb morphogenesis: connections between patterning and growth. Curr Biol. 7:1997;186-195.
    • (1997) Curr Biol , vol.7 , pp. 186-195
    • Serrano, N.1    O'Farrell, P.H.2
  • 24
    • 0032054994 scopus 로고    scopus 로고
    • Uncoupling growth from the cell cycle
    • Johnston LA Uncoupling growth from the cell cycle. Bioessays. 20:1998;283-286.
    • (1998) Bioessays , vol.20 , pp. 283-286
    • Johnston, L.A.1
  • 25
    • 0029747143 scopus 로고    scopus 로고
    • Ectopic E2F expression induces S phase and apoptosis in Drosophila imaginal discs
    • Asano M, Nevins JR, Wharton RP Ectopic E2F expression induces S phase and apoptosis in Drosophila imaginal discs. Genes Dev. 10:1996;1422-1432.
    • (1996) Genes Dev , vol.10 , pp. 1422-1432
    • Asano, M.1    Nevins, J.R.2    Wharton, R.P.3
  • 26
    • 0029954340 scopus 로고    scopus 로고
    • Ectopic expression of dE2F and dDP induces cell proliferation and death in the Drosophila eye
    • Du W, Xie JE, Dyson N Ectopic expression of dE2F and dDP induces cell proliferation and death in the Drosophila eye. EMBO J. 15:1996;3684-3692.
    • (1996) EMBO J , vol.15 , pp. 3684-3692
    • Du, W.1    Xie, J.E.2    Dyson, N.3
  • 27
    • 0028844991 scopus 로고
    • Ectopic cyclin E expression induces premature entry into S phase and disrupts pattern formation in the Drosophila eye imaginal disc
    • Richardson H, O'Keefe LV, Marty T, Saint R Ectopic cyclin E expression induces premature entry into S phase and disrupts pattern formation in the Drosophila eye imaginal disc. Development. 121:1995;3371-3379.
    • (1995) Development , vol.121 , pp. 3371-3379
    • Richardson, H.1    O'Keefe, L.V.2    Marty, T.3    Saint, R.4
  • 28
    • 0032568795 scopus 로고    scopus 로고
    • Coordination of growth and cell division in the Drosophila wing
    • An in-depth study of the role several key cell-cycle regulators play during wing imaginal growth. FACS analysis of isolated cells from dissociated imaginal tissue was used to examine cell-cycle phasing after overexpression of string, cyclin E, dE2F, or RBF. Clonal analysis was used to measure the contribution of these molecules to growth rates and cell division after their removal or overexpression. The principal conclusion is that changing the rate of cell division by manipulating these cell-cycle regulators does not affect rates of cell growth. Thus, growth is controlled independently of progress through the cell cycle. See also [31].
    • Neufeld TP, de la Cruz AF, Johnston LA, Edgar BA Coordination of growth and cell division in the Drosophila wing. Cell. 93:1998;1183-1193. An in-depth study of the role several key cell-cycle regulators play during wing imaginal growth. FACS analysis of isolated cells from dissociated imaginal tissue was used to examine cell-cycle phasing after overexpression of string, cyclin E, dE2F, or RBF. Clonal analysis was used to measure the contribution of these molecules to growth rates and cell division after their removal or overexpression. The principal conclusion is that changing the rate of cell division by manipulating these cell-cycle regulators does not affect rates of cell growth. Thus, growth is controlled independently of progress through the cell cycle. See also [31].
    • (1998) Cell , vol.93 , pp. 1183-1193
    • Neufeld, T.P.1    De La Cruz, A.F.2    Johnston, L.A.3    Edgar, B.A.4
  • 29
    • 0030003157 scopus 로고    scopus 로고
    • Requirements for dE2F function in proliferating cells and in post-mitotic differentiating cells
    • Brook A, Xie JE, Du W, Dyson N Requirements for dE2F function in proliferating cells and in post-mitotic differentiating cells. EMBO J. 15:1996;3676-3683.
    • (1996) EMBO J , vol.15 , pp. 3676-3683
    • Brook, A.1    Xie, J.E.2    Du, W.3    Dyson, N.4
  • 30
    • 0031950435 scopus 로고    scopus 로고
    • Analysis of a Drosophila cyclin E hypomorphic mutation suggests a novel role for cyclin E in cell proliferation control during eye imaginal disc development
    • Secombe J, Pispa J, Saint R, Richardson H Analysis of a Drosophila cyclin E hypomorphic mutation suggests a novel role for cyclin E in cell proliferation control during eye imaginal disc development. Genetics. 149:1998;1867-1882.
    • (1998) Genetics , vol.149 , pp. 1867-1882
    • Secombe, J.1    Pispa, J.2    Saint, R.3    Richardson, H.4
  • 31
    • 0030807904 scopus 로고    scopus 로고
    • Cell cycle progression, growth and patterning in imaginal discs despite inhibition of cell division after inactivation of Drosophila Cdc2 kinase
    • Weigmann K, Cohen SM, Lehner CF Cell cycle progression, growth and patterning in imaginal discs despite inhibition of cell division after inactivation of Drosophila Cdc2 kinase. Development. 124:1997;3555-3563.
    • (1997) Development , vol.124 , pp. 3555-3563
    • Weigmann, K.1    Cohen, S.M.2    Lehner, C.F.3
  • 32
    • 0032146274 scopus 로고    scopus 로고
    • The regulation of E2F by pRB-family proteins
    • Dyson N The regulation of E2F by pRB-family proteins. Genes Dev. 12:1998;2245-2262.
    • (1998) Genes Dev , vol.12 , pp. 2245-2262
    • Dyson, N.1
  • 33
    • 0030995824 scopus 로고    scopus 로고
    • Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F
    • Leone G, DeGregori J, Sears R, Jakoi L, Nevins JR Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F. Nature. 387:1997;422-426.
    • (1997) Nature , vol.387 , pp. 422-426
    • Leone, G.1    Degregori, J.2    Sears, R.3    Jakoi, L.4    Nevins, J.R.5
  • 35
    • 0031964429 scopus 로고    scopus 로고
    • Ectopic expression of activated Ras1 induces hyperplastic growth and increased cell death in Drosophila imaginal tissues
    • Karim FD, Rubin GM Ectopic expression of activated Ras1 induces hyperplastic growth and increased cell death in Drosophila imaginal tissues. Development. 125:1998;1-9.
    • (1998) Development , vol.125 , pp. 1-9
    • Karim, F.D.1    Rubin, G.M.2
  • 36
    • 0031860687 scopus 로고    scopus 로고
    • Environmental control of the cell cycle in Drosophila: Nutrition activates mitotic and endoreplicative cells by distinct mechanisms
    • Amino acids present in larval food are required to activate cell-cycle progression. This is not simply to satisfy a requirement for protein synthesis in individual cells but it somehow triggers a mitogenic signal throughout the animal. In the absence of such a signal, quiescent CNS neuroblasts are incapable of entering the cell cycle after overexpression of dE2F/dDP or cyclin E, whereas endoreduplicating cells are capable. This difference is caused in part by the neuroblast's requirement for a secreted growth factor found only in the larval fat body.
    • Britton JS, Edgar BA Environmental control of the cell cycle in Drosophila: nutrition activates mitotic and endoreplicative cells by distinct mechanisms. Development. 125:1998;2149-2158. Amino acids present in larval food are required to activate cell-cycle progression. This is not simply to satisfy a requirement for protein synthesis in individual cells but it somehow triggers a mitogenic signal throughout the animal. In the absence of such a signal, quiescent CNS neuroblasts are incapable of entering the cell cycle after overexpression of dE2F/dDP or cyclin E, whereas endoreduplicating cells are capable. This difference is caused in part by the neuroblast's requirement for a secreted growth factor found only in the larval fat body.
    • (1998) Development , vol.125 , pp. 2149-2158
    • Britton, J.S.1    Edgar, B.A.2
  • 37
    • 0027304169 scopus 로고
    • The Drosophila anachronism locus: A glycoprotein secreted by glia inhibits neuroblast proliferation
    • Ebens AJ, Garren H, Cheyette BN, Zipursky SL The Drosophila anachronism locus: a glycoprotein secreted by glia inhibits neuroblast proliferation. Cell. 74:1993;15-27.
    • (1993) Cell , vol.74 , pp. 15-27
    • Ebens, A.J.1    Garren, H.2    Cheyette, B.N.3    Zipursky, S.L.4
  • 38
    • 0028913038 scopus 로고
    • Control of proliferation activation in quiescent neuroblasts of the Drosophila central nervous system
    • Datta S Control of proliferation activation in quiescent neuroblasts of the Drosophila central nervous system. Development. 121:1995;1173-1182.
    • (1995) Development , vol.121 , pp. 1173-1182
    • Datta, S.1
  • 39
    • 0032445961 scopus 로고    scopus 로고
    • Expression of cyclin E or DP/E2F rescues the G1 arrest of trol mutant neuroblasts in the Drosophila larval central nervous system
    • 1-S cell cycle machinery.
    • 1-S cell cycle machinery.
    • (1998) Mech Dev , vol.79 , pp. 121-130
    • Caldwell, M.C.1    Datta, S.2
  • 40
    • 0028980858 scopus 로고
    • Developmental control of the G1 to S transition in Drosophila: Cyclin E is a limiting downstream target of E2F
    • Duronio RJ, O'Farrell PH Developmental control of the G1 to S transition in Drosophila: cyclin E is a limiting downstream target of E2F. Genes Dev. 9:1995;1456-1468.
    • (1995) Genes Dev , vol.9 , pp. 1456-1468
    • Duronio, R.J.1    O'Farrell, P.H.2
  • 41
    • 0003252542 scopus 로고
    • Development of the insect Malpighian tubule
    • T. Fleming. London: Chapman and Hall
    • Skaer H Development of the insect Malpighian tubule. Fleming T Epithelia in Development. 1992;191-218 Chapman and Hall, London.
    • (1992) Epithelia in Development , pp. 191-218
    • Skaer, H.1
  • 42
    • 0001409730 scopus 로고
    • Cell division in Malpighian tubule development in D. melanogaster is regulated by a single tip cell
    • Skaer H Cell division in Malpighian tubule development in D. melanogaster is regulated by a single tip cell. Nature. 342:1989;566-569.
    • (1989) Nature , vol.342 , pp. 566-569
    • Skaer, H.1
  • 43
    • 0028053438 scopus 로고
    • Sequential fates in a single cell are established by the neurogenic cascade in the Malpighian tubules of Drosophila
    • Hoch M, Broadie K, Jackle H, Skaer H Sequential fates in a single cell are established by the neurogenic cascade in the Malpighian tubules of Drosophila. Development. 120:1994;3439-3450.
    • (1994) Development , vol.120 , pp. 3439-3450
    • Hoch, M.1    Broadie, K.2    Jackle, H.3    Skaer, H.4
  • 44
    • 0027819163 scopus 로고
    • The Drosophila EGF receptor homologue (DER) is required for Malpighian tubule development
    • Baumann P, Skaer H The Drosophila EGF receptor homologue (DER) is required for Malpighian tubule development. Development. (Suppl):1993;65-75.
    • (1993) Development , Issue.SUPPL. , pp. 65-75
    • Baumann, P.1    Skaer, H.2
  • 45
    • 0032525978 scopus 로고    scopus 로고
    • Seven-up, the Drosophila homolog of the COUP-TF orphan receptors, controls cell proliferation in the insect kidney
    • This study describes a direct molecular connection between a signaling pathway and a cell-cycle regulator. Overexpression and mutations are used to assess the contribution of components of the EGF receptor pathway to cell proliferation in Drosophila Malpighian tubules. The Seven-up transcription factor is expressed in response to EGF signaling. Seven-up may then directly activate string transcription and drive the cell cycle.
    • Kerber B, Fellert S, Hoch M Seven-up, the Drosophila homolog of the COUP-TF orphan receptors, controls cell proliferation in the insect kidney. Genes Dev. 12:1998;1781-1786. This study describes a direct molecular connection between a signaling pathway and a cell-cycle regulator. Overexpression and mutations are used to assess the contribution of components of the EGF receptor pathway to cell proliferation in Drosophila Malpighian tubules. The Seven-up transcription factor is expressed in response to EGF signaling. Seven-up may then directly activate string transcription and drive the cell cycle.
    • (1998) Genes Dev , vol.12 , pp. 1781-1786
    • Kerber, B.1    Fellert, S.2    Hoch, M.3
  • 46
    • 0026440061 scopus 로고
    • The wingless product is required for cell proliferation in the Malpighian tubule anlage of Drosophila melanogaster
    • Skaer H, Martinez-Arias A The wingless product is required for cell proliferation in the Malpighian tubule anlage of Drosophila melanogaster. Development. 116:1992;745-754.
    • (1992) Development , vol.116 , pp. 745-754
    • Skaer, H.1    Martinez-Arias, A.2
  • 47
    • 0023408608 scopus 로고
    • Changing spatial patterns of DNA replication in the developing wing of Drosophila
    • Schubiger M, Palka J Changing spatial patterns of DNA replication in the developing wing of Drosophila. Dev Biol. 123:1987;145-153.
    • (1987) Dev Biol , vol.123 , pp. 145-153
    • Schubiger, M.1    Palka, J.2
  • 48
    • 0021995389 scopus 로고
    • A zone of non-proliferating cells at a lineage restriction boundary in Drosophila
    • O'Brochta DA, Bryant PJ A zone of non-proliferating cells at a lineage restriction boundary in Drosophila. Nature. 313:1985;138-141.
    • (1985) Nature , vol.313 , pp. 138-141
    • O'Brochta, D.A.1    Bryant, P.J.2
  • 49
    • 0032474776 scopus 로고    scopus 로고
    • Wingless and Notch regulate cell-cycle arrest in the developing Drosophila wing
    • ••], the results provide one of the few examples where a molecular pathway from developmental signaling molecule to cell-cycle regulator can be described.
    • ••], the results provide one of the few examples where a molecular pathway from developmental signaling molecule to cell-cycle regulator can be described.
    • (1998) Nature , vol.394 , pp. 82-84
    • Johnston, L.A.1    Edgar, B.A.2
  • 51
    • 0028802458 scopus 로고
    • Cell fate specification by even-skipped expression in the Drosophila nervous system is coupled to cell cycle progression
    • Weigmann K, Lehner CF Cell fate specification by even-skipped expression in the Drosophila nervous system is coupled to cell cycle progression. Development. 121:1995;3713-3721.
    • (1995) Development , vol.121 , pp. 3713-3721
    • Weigmann, K.1    Lehner, C.F.2
  • 52
    • 0028784018 scopus 로고
    • The role of the cell cycle and cytokinesis in regulating neuroblast sublineage gene expression in the Drosophila CNS
    • Cui X, Doe CQ The role of the cell cycle and cytokinesis in regulating neuroblast sublineage gene expression in the Drosophila CNS. Development. 121:1995;3233-3243.
    • (1995) Development , vol.121 , pp. 3233-3243
    • Cui, X.1    Doe, C.Q.2
  • 53
    • 0028178124 scopus 로고
    • Developmental control of a G1-S transcriptional program in Drosophila
    • Duronio RJ, O'Farrell PH Developmental control of a G1-S transcriptional program in Drosophila. Development. 120:1994;1503-1515.
    • (1994) Development , vol.120 , pp. 1503-1515
    • Duronio, R.J.1    O'Farrell, P.H.2
  • 54
    • 0031439866 scopus 로고    scopus 로고
    • The tao of stem cells in the germline
    • Lin H The tao of stem cells in the germline. Annu Rev Genet. 31:1997;455-491.
    • (1997) Annu Rev Genet , vol.31 , pp. 455-491
    • Lin, H.1
  • 55
    • 0032563165 scopus 로고    scopus 로고
    • Decapentaplegic is essential for the maintenance and division of germline stem cells in the Drosophila ovary
    • This study provides evidence that Dpp signaling directly maintains stem cell divisions and identity in the Drosophila female germline. This is a seminal observation in that the precise genetic mechanisms controlling stem cell proliferation are largely unknown.
    • Xie T, Spradling AC Decapentaplegic is essential for the maintenance and division of germline stem cells in the Drosophila ovary. Cell. 94:1998;251-260. This study provides evidence that Dpp signaling directly maintains stem cell divisions and identity in the Drosophila female germline. This is a seminal observation in that the precise genetic mechanisms controlling stem cell proliferation are largely unknown.
    • (1998) Cell , vol.94 , pp. 251-260
    • Xie, T.1    Spradling, A.C.2
  • 56
    • 0028247039 scopus 로고
    • Cell cycle progression in the developing Drosophila eye: Roughex encodes a novel protein required for the establishment of G1
    • Thomas BJ, Gunning DA, Cho J, Zipursky L Cell cycle progression in the developing Drosophila eye: roughex encodes a novel protein required for the establishment of G1. Cell. 77:1994;1003-1014.
    • (1994) Cell , vol.77 , pp. 1003-1014
    • Thomas, B.J.1    Gunning, D.A.2    Cho, J.3    Zipursky, L.4
  • 58
    • 0031040449 scopus 로고    scopus 로고
    • Induction of Drosophila eye development by decapentaplegic
    • Pignoni F, Zipursky SL Induction of Drosophila eye development by decapentaplegic. Development. 124:1997;271-278.
    • (1997) Development , vol.124 , pp. 271-278
    • Pignoni, F.1    Zipursky, S.L.2
  • 59
    • 0031047533 scopus 로고    scopus 로고
    • Role of decapentaplegic in initiation and progression of the morphogenetic furrow in the developing Drosophila retina
    • Chanut F, Heberlein U Role of decapentaplegic in initiation and progression of the morphogenetic furrow in the developing Drosophila retina. Development. 124:1997;559-567.
    • (1997) Development , vol.124 , pp. 559-567
    • Chanut, F.1    Heberlein, U.2
  • 60
    • 0031022423 scopus 로고    scopus 로고
    • Regulation of cell cycle synchronization by decapentaplegic during Drosophila eye development
    • Penton A, Selleck SB, Hoffmann FM Regulation of cell cycle synchronization by decapentaplegic during Drosophila eye development. Science. 275:1997;203-206.
    • (1997) Science , vol.275 , pp. 203-206
    • Penton, A.1    Selleck, S.B.2    Hoffmann, F.M.3
  • 61
    • 0032430726 scopus 로고    scopus 로고
    • Decapentaplegic is required for arrest in G1 phase during Drosophila eye development
    • 1 phase of the cell cycle during patterned differentiation in eye imaginal discs. This is in contrast to Dpp's more established role in stimulating growth and proliferation of wing imaginal cells.
    • 1 phase of the cell cycle during patterned differentiation in eye imaginal discs. This is in contrast to Dpp's more established role in stimulating growth and proliferation of wing imaginal cells.
    • (1998) Development , vol.125 , pp. 5069-5078
    • Horsfield, J.1    Penton, A.2    Secombe, J.3    Hoffman, F.M.4    Richardson, H.5
  • 62
    • 0030473888 scopus 로고    scopus 로고
    • A cyclin-dependent kinase inhibitor, Dacapo, is necessary for timely exit from the cell cycle during Drosophila embryogenesis
    • de Nooij JC, Letendre MA, Hariharan IK A cyclin-dependent kinase inhibitor, Dacapo, is necessary for timely exit from the cell cycle during Drosophila embryogenesis. Cell. 87:1996;1237-1247.
    • (1996) Cell , vol.87 , pp. 1237-1247
    • De Nooij, J.C.1    Letendre, M.A.2    Hariharan, I.K.3
  • 63
    • 0030468329 scopus 로고    scopus 로고
    • Dacapo, a cyclin-dependent kinase inhibitor, stops cell proliferation during Drosophila development
    • Lane ME, Sauer K, Wallace K, Jan YN, Lehner CF, Vaessin H Dacapo, a cyclin-dependent kinase inhibitor, stops cell proliferation during Drosophila development. Cell. 87:1996;1225-1235.
    • (1996) Cell , vol.87 , pp. 1225-1235
    • Lane, M.E.1    Sauer, K.2    Wallace, K.3    Jan, Y.N.4    Lehner, C.F.5    Vaessin, H.6
  • 64
    • 0031723067 scopus 로고    scopus 로고
    • A Drosophila RNA helicase gene, pitchoune, is required for cell growth and proliferation and is a potential target of d-Myc
    • Zaffran S, Chartier A, Gallant P, Astier M, Arquier N, Doherty D, Gratecos D, Semeriva M A Drosophila RNA helicase gene, pitchoune, is required for cell growth and proliferation and is a potential target of d-Myc. Development. 125:1998;3571-3584.
    • (1998) Development , vol.125 , pp. 3571-3584
    • Zaffran, S.1    Chartier, A.2    Gallant, P.3    Astier, M.4    Arquier, N.5    Doherty, D.6    Gratecos, D.7    Semeriva, M.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.