Retroviral gene transfer into human hematopoietic cells: An in vitro kinetic study

Haematologica

Volumn 84, Issue 6, 1999, Pages 483-488

  Briones, Javier ^a,b   Puig, Teresa ^b   Limón, Ana ^b   Pétriz, Jordi ^b   García, Joan ^b   Barquinero, Jordi ^b  

^a HOSPITAL DE LA SANTA CREU I SANT PAU   (Spain)

^b Institut de Recerca Oncologica   (Spain)

Author keywords

Gene transfer; Hematopoietic cells; Retroviral vectors

Indexed keywords

CD34 ANTIGEN; FLT3 LIGAND; GREEN FLUORESCENT PROTEIN; INTERLEUKIN 3; INTERLEUKIN 6; STEM CELL FACTOR;

ANTIGEN EXPRESSION; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CLONING VECTOR; CONTROLLED STUDY; GENE TRANSFER; HEMATOPOIETIC CELL; HUMAN; HUMAN CELL; LEUKAPHERESIS; RETROVIRUS; UMBILICAL CORD BLOOD;

ANTIGENS, CD34; CELLS, CULTURED; GENE TRANSFER TECHNIQUES; GENES, VIRAL; GENETIC VECTORS; GREEN FLUORESCENT PROTEINS; HEMATOPOIETIC STEM CELLS; HUMANS; LUMINESCENT PROTEINS; RETROVIRIDAE; TIME FACTORS; TRANSDUCTION, GENETIC;

EID: 0033038835     PISSN: 03906078     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Brenner MK, Heslop HE, Rill D, et al. Transfer of marker genes into hematopoietic progenitor cells. Cytokines Mol Ther 1996; 2:193-200.
2. + cells for six hours without growth factors or on autologous stroma does not improve marking efficiency assessed in vivo. Blood 1997; 89:4040-6.
3. Mavilio F, Ferrari G, Rossini S, et al. Peripheral blood lymphocytes as target cells of retroviral vector-mediated gene transfer. Blood 1994; 83:1988-97.
4. Phillips K, Gentry T, McCowage G, Gilboa E, Smith C. Cell-surface markers for assessing gene transfer into human hematopoietic cells. Nature Med 1996; 2: 1154-6.
5. Conneally E, Bardy P, Eaves CJ, et al. Rapid and efficient selection of human hematopoietic cells expressing murine heat-stable antigen as an indicator of retroviral-mediated gene transfer. Blood 1996; 87:456-64.
6. Eipers PG, Krauss JC, Palsson BO, Emerson SG, Todd RF III, Clarke MF. Retroviral-mediated gene transfer in human bone marrow cells grown in continuous perfusion culture vessels. Blood 1996; 86:3754-62.
7. Pawliuk R, Kay R, Lansdorp PM, Humphries RK. Selection of retrovirally transduced hematopoietic cells using CD24 as a marker of gene transfer. Blood 1994; 84:2868-77.
8. Chalfie M, Tu Y, Euskirchen G, Ward WW, Prasher DC. Green fluorescent protein as a marker for gene expression. Science 1994; 263:802-5.
9. Persons DA, Allay JA, Allay ER, et al. Retroviral-mediated transfer of the green fluorescent protein gene into murine hematopoietic cells facilitates scoring and selection of transduced progenitors in vitro and identification of genetically modified cells in vivo. Blood 1997; 90:1777-86.
10. Bierhuizen MFA, Westerman Y, Visser TP, Dimjati W, Wognum AW, Wagemaker G. Enhanced green fluorescent protein as selectable marker of retroviral-mediated gene transfer in immature hematopoietic bone marrow cells. Blood 1997; 90:3304-15.
11. Limon A, Briones J, Puig T, et al. High-titer retroviral vectors containing enhanced green fluorescent protein (EGFP) for efficient expression in hematopoietic cells. Blood 1997; 90:3316-21.
12. +++ human umbilical cord blood hematopoietic progenitors with high proliferative and replating potential. Blood 1993; 81:41-8.
13. + cells expanded in vitro. Exp Hematol 1994; 22:1171-8.
14. Bienzle D, Abrams-Ogg ACG, Kruth SA, et al. Gene transfer into hematopoietic stem cells: Long-term maintenance of in vitro activated progenitors without marrow ablation. Proc Natl Acad Sci USA 1994; 91: 350-4.
15. von Kalle C, Kiem HP, Goehle S, et al. Increased gene transfer into human hematopoietic progenitor cells by extended in vitro exposure to a pseudotyped retroviral vector. Blood 1994; 84:2890-7.
16. Cancelas JA, Querol S, Canals C, et al. CD34+ cell positive selection from mobilized peripheral blood by an indirect immunomagnetic method: effect of the type of mobilization and assessment of tumor depletion ability. J Hematother 1995; 4:531-8.
17. Rao SS, Peters SO, Crittenden RB, Stewart FM, Ramshaw HS, Quesenberry PJ. Stem cell transplantation in the normal nonmyeloablated host: relationship between cell dose, schedule, and engraftment. Exp Hematol 1997; 25:114-21.
18. Kittler ELW, Peters SO, Crittenden RB, et al. Cytokine-facilitated transduction leads to low level engraftment in nonablated hosts. Blood 1997; 90:865-72.
19. Peters SO, Kittler ELW, Ramshaw HS, Quesenberry PJ. Ex vivo expansion of murine marrow cells with interleukin-3 (IL-3), IL-6, IL-11 and stem cell factor leads to impaired engraftment in irradiated hosts. Blood 1996; 87:30-7.
20. Williams DA, Lemischka IR, Nathan DG, Mulligan RC. Introduction of new genetic material into pluripotent haematopoietic stem cells of the mouse. Nature 1984: 310:476-80.
21. van Beusechem VW, Valerio D. Gene transfer into hematopoietic stem cells of nonhuman primates. Hum Gene Ther 1996; 7:1649-68.
22. Serrano F, Varas F, Bernad A, Bueren JA. Accelerated and long-term hematopoietic engraftment in mice transplanted with ex vivo expanded bone marrow. Bone Marrow Transplant 1994; 14:855-62.
23. Varas F, Bernad A, Almendral JM, Bueren JA. Relevance of myeloablative conditioning in the engraftment of limiting numbers of normal and genetically marked lympho-hematopoietic stem cells. Bone Marrow Transplant 1994; 18:981-9.
24. Haylock DN, To LB, Dowse TL, Juttner CA, Simmons PJ. Ex vivo expansion and maturation of peripheral blood CD34+ cells into the myeloid lineage. Blood 1992; 80:1405-12.
25. Traycoff CM, Orazi A, Ladd AC, Rice S, McMahel J, Srour EF. Proliferation-induced decline of primitive hematopoietic progenitor cell activity is coupled with an increase in apoptosis of ex vivo expanded CD34+ cells. Exp Hematol 1998; 26:53-62.
26. Douer D, Ramezani L, Mohrbacher AF, et al. The influence of patient-related factors on ex vivo retroviral-mediated gene transfer into mobilized peripheral blood myeloid progenitors. Hum Gene Ther 1998; 9:1061-8.
27. Dunbar CE, Cottler-Fox M, O'Shaughnessy JA, et al. Retrovirally marked CD34-enriched peripheral blood and bone marrow cells contribute to long-term engraftment after autologous transplantation. Blood 1993; 85:3048-57.
28. Bregni M, Di Nicola M, Siena S, et al. Mobilized peripheral blood CD34+ cells express more amphotropic retrovirus receptor than bone marrow CD34+ cells. Haematologica 1998; 83:204-8.
29. Lansdorp PM, Dragowska W, Mayani H. Ontogeny-related changes in proliferative potential of human hematopoietic cells. J Exp Med 1993; 178:787-91.
30. Al-Lebban ZS, Henry JM, Jones JB, Eglitis MA, Anderson WF, Lothrop CD Jr. Increased efficiency of gene transfer with retroviral vectors in neonatal hematopoietic progenitor cells. Exp Hematol 1990; 18:180-4.
31. Levy JP, Muldoon RR, Zolotukhin S, Link Jr CJ. Retroviral transfer and expression of a humanized, red-shifted green fluorescent protein gene into human tumor cells. Nat Biotechnol 1996; 14:610-4.
32. Cheng L, Du C, Lavau C, et al. Sustained gene expression in retrovirally transduced, engrafting human hematopoietic stem cells and their lympho-myeloid progeny. Blood 1998; 92:83-92.
33. Corrias MV, Scuderi F, Pasino M, et al. Growth factors increase retroviral transduction but decrease clonogenic potential of umbilical cord blood CD34+ cells. Haematologica 1998; 83:580-6.