Activation of the endothelin receptor inhibits the G protein-coupled inwardly rectifying potassium channel by a phospholipase A2-mediated mechanism

Journal of Neurochemistry

Volumn 72, Issue 4, 1999, Pages 1409-1416

  Rogalski, Sherri L ^a   Cyr, Curt ^a,b   Chavkin, Charles ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b Maine Medical Center Research Institute   (United States)

Author keywords

Arachidonic acid; Channel modulation; G protein coupled inwardly rectifying potassium channel (GIRK); Opioid receptors; Protein kinase C; Receptor cross talk

Indexed keywords

ARACHIDONIC ACID; ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; GENISTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN; ICOSANOID; MU OPIATE RECEPTOR; PHOSPHOLIPASE A2; PHOSPHOLIPASE A2 INHIBITOR; POTASSIUM CHANNEL; POTASSIUM ION; STAUROSPORINE;

ANIMAL CELL; ARTICLE; CHELATION; CONTROLLED STUDY; ENZYME ACTIVATION; NONHUMAN; NUCLEOTIDE SEQUENCE; OOCYTE; POTASSIUM CURRENT; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; VOLTAGE CLAMP; XENOPUS LAEVIS;

ANALGESICS, OPIOID; ANIMALS; ANIONS; ARACHIDONIC ACID; CALCIUM; CHELATING AGENTS; EGTAZIC ACID; ENDOTHELIN-1; ENKEPHALIN, ALA(2)-MEPHE(4)-GLY(5)-; ENKEPHALINS; ENZYME INHIBITORS; FEMALE; G PROTEIN-COUPLED INWARDLY-RECTIFYING POTASSIUM CHANNELS; GENE EXPRESSION; GTP-BINDING PROTEINS; ION CHANNEL GATING; OOCYTES; PHOSPHOLIPASES A; PHOSPHOPROTEIN PHOSPHATASE; POTASSIUM CHANNELS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; PROTEIN KINASE C; RATS; RECEPTOR CROSS-TALK; RECEPTORS, ENDOTHELIN; RECEPTORS, MUSCARINIC; RECEPTORS, OPIOID, MU; STAUROSPORINE; XENOPUS LAEVIS;

ANIMALIA; XENOPUS LAEVIS;

EID: 0033037908     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1999.721409.x     Document Type: Article

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