Artemisinin and its derivatives are transported by a vacuolar-network of Plasmodium falciparum and their anti-malarial activities are additive with toxic sphingolipid analogues that block the network

Molecular and Biochemical Parasitology

Volumn 101, Issue 1-2, 1999, Pages 71-79

  Akompong, Thomas ^a   Vanwye, Jeffrey ^a   Ghori, Nafisa ^a   Haldar, Kasturi ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Antimalarial; Artemisinin; Drug transport; Malaria; Plasmodium falciparum

Indexed keywords

ANTIMALARIAL AGENT; ARTEMISIN DERIVATIVE; ARTEMISININ; DIHYDROARTEMISININ; MEMBRANE PROTEIN; SPHINGOLIPID;

ANTIMALARIAL ACTIVITY; ARTICLE; DRUG TRANSPORT; ELECTRON MICROSCOPY; ERYTHROCYTE; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; NONHUMAN; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL;

ANIMALS; ANTIMALARIALS; ARTEMISININS; BIOLOGICAL TRANSPORT; CHLOROQUINE; DRUG RESISTANCE; DRUG SYNERGISM; ERYTHROCYTES; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; HUMANS; MALARIA, FALCIPARUM; MEMBRANE PROTEINS; MICROSCOPY, ELECTRON; PLASMODIUM FALCIPARUM; PROTOZOAN PROTEINS; SESQUITERPENES; SPHINGOLIPIDS; VACUOLES;

PLASMODIUM FALCIPARUM;

EID: 0033035811     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-6851(99)00056-0     Document Type: Article

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