메뉴 건너뛰기




Volumn 19, Issue 1, 1999, Pages 45-56

Carnosine: An endogenous neuroprotector in the ischemic brain

Author keywords

Antioxidants; Brain; Carnosine; Carnosine related compounds; Ischemia; Reactive oxygen species

Indexed keywords

CARNOSINE; LACTIC ACID; REACTIVE OXYGEN METABOLITE;

EID: 0033035212     PISSN: 02724340     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1006960407008     Document Type: Article
Times cited : (50)

References (47)
  • 1
    • 0027279474 scopus 로고
    • Longitudinal change in proton magnetic resonance spectroscopy in cerebral infarction
    • Abe, H., and Kashiwaba, T. (1993). Longitudinal change in proton magnetic resonance spectroscopy in cerebral infarction. Stroke 24:1316-1321.
    • (1993) Stroke , vol.24 , pp. 1316-1321
    • Abe, H.1    Kashiwaba, T.2
  • 2
    • 0024788706 scopus 로고
    • Carnosine, homocarnosine and serine: Could they act as antioxidants in vivo?
    • Aruoma, O. I., Laughton, M. J., and Halliwell, B. (1989). Carnosine, homocarnosine and serine: Could they act as antioxidants in vivo? Biochem. J. 264:863-869.
    • (1989) Biochem. J. , vol.264 , pp. 863-869
    • Aruoma, O.I.1    Laughton, M.J.2    Halliwell, B.3
  • 3
    • 0025175995 scopus 로고
    • Biochemical aspects of free radicals
    • Basaga, H. S. (1990). Biochemical aspects of free radicals. Biochem.Cell Biol. 68:989-998.
    • (1990) Biochem.Cell Biol. , vol.68 , pp. 989-998
    • Basaga, H.S.1
  • 4
    • 0025370413 scopus 로고
    • Cellular localization of carnosine-like and anserine-like immunoreactivity in rodent and avian central nervous system
    • Biffo, S., Grillo, M., and Margolis, F. L. (1990). Cellular localization of carnosine-like and anserine-like immunoreactivity in rodent and avian central nervous system. Neuroscience 35:637-651.
    • (1990) Neuroscience , vol.35 , pp. 637-651
    • Biffo, S.1    Grillo, M.2    Margolis, F.L.3
  • 5
    • 0027293651 scopus 로고
    • Does carnosine possess direct antioxidant activity?
    • Boldyrev, A. A. (1993). Does carnosine possess direct antioxidant activity? Int. J. Biochem. 25:1101-1107.
    • (1993) Int. J. Biochem. , vol.25 , pp. 1101-1107
    • Boldyrev, A.A.1
  • 6
    • 0012334939 scopus 로고
    • Paradoxes of oxidative metabolism of the brain
    • Boldyrev, A. A. (1995). Paradoxes of oxidative metabolism of the brain. Biochemistry (Moscow) 60:1173-1177.
    • (1995) Biochemistry (Moscow) , vol.60 , pp. 1173-1177
    • Boldyrev, A.A.1
  • 7
    • 0025081749 scopus 로고
    • The histidine-containing dipeptides, carnosine and anserine: Distribution, properties and biological significance
    • Weber, J. (ed.), Pergamon Press, London
    • Boldyrev, A. A., and Severin, S. E. (1990). The histidine-containing dipeptides, carnosine and anserine: Distribution, properties and biological significance. In Weber, J. (ed.), Advances in Enzymes Regulation, Pergamon Press, London, Vol. 30, pp. 175-194.
    • (1990) Advances in Enzymes Regulation , vol.30 , pp. 175-194
    • Boldyrev, A.A.1    Severin, S.E.2
  • 8
    • 0023776655 scopus 로고
    • Antioxidative properties of histidine-containing dipeptides from skeletal muscles of vertebrates
    • Boldyrev, A. A., Dupin, A. M., Pindel, E. V., and Severin, S. E. (1988). Antioxidative properties of histidine-containing dipeptides from skeletal muscles of vertebrates. Comp. Biochem. Physiol. 89B:245-250.
    • (1988) Comp. Biochem. Physiol. , vol.89 B , pp. 245-250
    • Boldyrev, A.A.1    Dupin, A.M.2    Pindel, E.V.3    Severin, S.E.4
  • 9
  • 10
    • 0028875264 scopus 로고
    • Effects of carnosine and related compounds on generation of free oxygen species: A comparative study
    • Boldyrev, A. A., Abe, H., Stvolinsky, S. L., and Tyulina, O. V. (1995). Effects of carnosine and related compounds on generation of free oxygen species: A comparative study. Comp. Biochem. Physiol. 112B:481-485.
    • (1995) Comp. Biochem. Physiol. , vol.112 B , pp. 481-485
    • Boldyrev, A.A.1    Abe, H.2    Stvolinsky, S.L.3    Tyulina, O.V.4
  • 12
    • 0030892429 scopus 로고    scopus 로고
    • Biochemical and physiological evidence that carnosine is an endogenous neuroprotector against free radicals
    • Boldyrev, A. A., Stvolinsky, S. L., Tyulina, O. V., Koshelev, V. B., Hori, N., and Carpenter, D. O. (1997). Biochemical and physiological evidence that carnosine is an endogenous neuroprotector against free radicals. Cell. Mol. Neurobiol. 17:259-271.
    • (1997) Cell. Mol. Neurobiol. , vol.17 , pp. 259-271
    • Boldyrev, A.A.1    Stvolinsky, S.L.2    Tyulina, O.V.3    Koshelev, V.B.4    Hori, N.5    Carpenter, D.O.6
  • 13
    • 0023154254 scopus 로고
    • MR-imaging and spectroscopy in clinical and experimental cerebral ischemia
    • Brant-Zawadski, M., Weintein, P., Bartkowski, K., and Moseley, M. (1987). MR-imaging and spectroscopy in clinical and experimental cerebral ischemia. Am. J. Roentgenol. 148:579-588.
    • (1987) Am. J. Roentgenol. , vol.148 , pp. 579-588
    • Brant-Zawadski, M.1    Weintein, P.2    Bartkowski, K.3    Moseley, M.4
  • 14
    • 0010471495 scopus 로고
    • Cellular defences against damage from reactive oxygen species
    • Byung, P. Y. (1994). Cellular defences against damage from reactive oxygen species. Physiol. Rev. 74:139-162.
    • (1994) Physiol. Rev. , vol.74 , pp. 139-162
    • Byung, P.Y.1
  • 15
    • 0028185906 scopus 로고
    • Endogenous skeletal muscle antioxidants
    • Chan, K. N., and Decker, E. A. (1994). Endogenous skeletal muscle antioxidants. Crit. Rev. Food Sci. Nutr. 34:403-426.
    • (1994) Crit. Rev. Food Sci. Nutr. , vol.34 , pp. 403-426
    • Chan, K.N.1    Decker, E.A.2
  • 17
    • 0014785883 scopus 로고
    • Carnosine and related substances in animal tissues
    • Crush, K. M. (1970). Carnosine and related substances in animal tissues. Comp. Biochem. Physiol. 34:3-10.
    • (1970) Comp. Biochem. Physiol. , vol.34 , pp. 3-10
    • Crush, K.M.1
  • 18
    • 0026629644 scopus 로고
    • Applications of magnetic resonance spectroscopy to the investigation of neuropsychiatrie disorders
    • Dager, S. R., and Steen, R. G. (1992). Applications of magnetic resonance spectroscopy to the investigation of neuropsychiatrie disorders. Neuropsychopharmacology 6:249-266.
    • (1992) Neuropsychopharmacology , vol.6 , pp. 249-266
    • Dager, S.R.1    Steen, R.G.2
  • 19
    • 0025967251 scopus 로고
    • Antioxidant nutrients and disease prevention overview
    • Diplock, A. T. (1991). Antioxidant nutrients and disease prevention overview. Am. J. Clin. Nutr. 53 (Suppl):189S-193S.
    • (1991) Am. J. Clin. Nutr. , vol.53 , Issue.SUPPL.
    • Diplock, A.T.1
  • 22
    • 0026922585 scopus 로고
    • Characterization of chloramine complexes of carnosine with hypochlorite anions
    • Formaziuk, V. E., Gorshkova, N. Yu., Boldyrev, A. A., and Sergienko, V. I. (1992). Characterization of chloramine complexes of carnosine with hypochlorite anions. Biochemistry (Moscow) 57:1324-1329.
    • (1992) Biochemistry (Moscow) , vol.57 , pp. 1324-1329
    • Formaziuk, V.E.1    Yu, G.N.2    Boldyrev, A.A.3    Sergienko, V.I.4
  • 23
    • 0020427486 scopus 로고
    • Biology of disease: Free radicals and tissue injury
    • Freeman, B. A., and Crapo, J. D. (1982). Biology of disease: Free radicals and tissue injury. Lab. Invest. 47:412-426.
    • (1982) Lab. Invest. , vol.47 , pp. 412-426
    • Freeman, B.A.1    Crapo, J.D.2
  • 24
    • 0028522661 scopus 로고
    • Correlation between cerebral blood flow and neuronal activity in the groups of animals with different susceptibility to the emotional stress predictor of hardness of brain ischemia
    • in Russian
    • Gannushkina, I. V., Antelava, A. L., and Baranchikova, M. V. (1994). Correlation between cerebral blood flow and neuronal activity in the groups of animals with different susceptibility to the emotional stress predictor of hardness of brain ischemia. Bull. Exp. Biol. Med. (Moscow) 118(N10):360-363 (in Russian).
    • (1994) Bull. Exp. Biol. Med. (Moscow) , vol.118 , Issue.N10 , pp. 360-363
    • Gannushkina, I.V.1    Antelava, A.L.2    Baranchikova, M.V.3
  • 27
    • 0028643643 scopus 로고
    • Hydroxyl radicals, ions, oxidative stress and neurodegeneration
    • Gutteridge, J. M. C. (1994). Hydroxyl radicals, ions, oxidative stress and neurodegeneration. Ann. N.Y. Acad. Sci. 738:201-213.
    • (1994) Ann. N.Y. Acad. Sci. , vol.738 , pp. 201-213
    • Gutteridge, J.M.C.1
  • 28
    • 0016745250 scopus 로고
    • An improved method for the preparation of synaptosomal fraction in high purity
    • Hajos, F. (1975). An improved method for the preparation of synaptosomal fraction in high purity. Brain Res. 93:185-189.
    • (1975) Brain Res. , vol.93 , pp. 185-189
    • Hajos, F.1
  • 29
  • 30
    • 0026636441 scopus 로고
    • Free radicals, antioxidants, and human disease: Where are we now?
    • Halliwell, B., and Gutteridge, J. M. C., and Cross, C. E. (1992). Free radicals, antioxidants, and human disease: Where are we now? J. Lab. Clin. Med. 119:598-620.
    • (1992) J. Lab. Clin. Med. , vol.119 , pp. 598-620
    • Halliwell, B.1    Gutteridge, J.M.C.2    Cross, C.E.3
  • 31
    • 0027465616 scopus 로고
    • Application of magnetic resonance spectroscopy and diffusion-weighted imaging to the study of brain biochemistry and pathology
    • Kauppinen, R. A., Williams, S. R., Busza, A. L., and van Bruggen, N. (1993). Application of magnetic resonance spectroscopy and diffusion-weighted imaging to the study of brain biochemistry and pathology. Trends Neurosci. 16:88-95.
    • (1993) Trends Neurosci. , vol.16 , pp. 88-95
    • Kauppinen, R.A.1    Williams, S.R.2    Busza, A.L.3    Van Bruggen, N.4
  • 32
    • 0026667919 scopus 로고
    • Polymorphonuclear leukocytes and monocytes/macrophages in the pathogenesis of cerebral ischemia and stroke
    • Kochanek, P. M., and Hallenbeck, J. M. (1992). Polymorphonuclear leukocytes and monocytes/macrophages in the pathogenesis of cerebral ischemia and stroke. Stroke 23:1367-1379.
    • (1992) Stroke , vol.23 , pp. 1367-1379
    • Kochanek, P.M.1    Hallenbeck, J.M.2
  • 33
    • 0344158770 scopus 로고
    • Antioxidant activity of carnosine, homocarnosine and anserine present in muscles and brain
    • Kohen, R., Yamamoto, J., Cundy, K. C., and Ames, B. (1988). Antioxidant activity of carnosine, homocarnosine and anserine present in muscles and brain. Proc. Natl. Acad. Sci. USA 85:3174-3179.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 3174-3179
    • Kohen, R.1    Yamamoto, J.2    Cundy, K.C.3    Ames, B.4
  • 35
    • 0033035317 scopus 로고    scopus 로고
    • Oxidative resistance of Na/K ATPase from brain and kidney
    • Kurella, E. G., Tyulina, O. V., and Boldyrev, A. A. (1999). Oxidative resistance of Na/K ATPase from brain and kidney. Cell. Mol. Neurobiol. 19:133-140.
    • (1999) Cell. Mol. Neurobiol. , vol.19 , pp. 133-140
    • Kurella, E.G.1    Tyulina, O.V.2    Boldyrev, A.A.3
  • 36
    • 0013970039 scopus 로고
    • Effects of ischemia and other procedures on the brain and retina of the gerbil (Meriones unguiculatus)
    • Levine, S., and Payan, H. (1966). Effects of ischemia and other procedures on the brain and retina of the gerbil (Meriones unguiculatus). Exp. Neurol. 16:255-262.
    • (1966) Exp. Neurol. , vol.16 , pp. 255-262
    • Levine, S.1    Payan, H.2
  • 37
    • 0016212865 scopus 로고
    • Carnosine in the primary olfactory bulb
    • Margolis, F. L. (1974). Carnosine in the primary olfactory bulb. Science 184:909-911.
    • (1974) Science , vol.184 , pp. 909-911
    • Margolis, F.L.1
  • 38
    • 0017368168 scopus 로고
    • Experimental cerebral infarction effects of pentobarbital in mongolian gerbils
    • McGraw, C. P. (1977). Experimental cerebral infarction effects of pentobarbital in mongolian gerbils. Arch. Neurol. 34:334-336.
    • (1977) Arch. Neurol. , vol.34 , pp. 334-336
    • McGraw, C.P.1
  • 39
    • 0028144566 scopus 로고
    • Diffusion-weighted magnetic resonance imaging of acute focal cerebral ischemia: Comparison of signal intensity with changes in brain water and Na/K-ATPase activity
    • Mintorovitch, J., Yang, G. Y., Shimizu, H., Kucharczyk, J., Chan, P. H., and Weinstein, P. R. (1994). Diffusion-weighted magnetic resonance imaging of acute focal cerebral ischemia: Comparison of signal intensity with changes in brain water and Na/K-ATPase activity. J. Cerebr. Blood Flow Metab. 14:332-336.
    • (1994) J. Cerebr. Blood Flow Metab. , vol.14 , pp. 332-336
    • Mintorovitch, J.1    Yang, G.Y.2    Shimizu, H.3    Kucharczyk, J.4    Chan, P.H.5    Weinstein, P.R.6
  • 40
  • 41
    • 0027252145 scopus 로고
    • Mechanisms of drug actions against neuronal damage caused by ischemia - An overview
    • Peruche, B., and Krieglstein, J. (1993). Mechanisms of drug actions against neuronal damage caused by ischemia - An overview. Prog. Neuro-Psychopharmacol. Biol. Psychiatry 17:21-70.
    • (1993) Prog. Neuro-Psychopharmacol. Biol. Psychiatry , vol.17 , pp. 21-70
    • Peruche, B.1    Krieglstein, J.2
  • 42
    • 0018347695 scopus 로고
    • A new model of bilateral hemispheric ischemia in the unanesthetized rat
    • Pulsinelly, W. A., and Brierley, F. B. (1979). A new model of bilateral hemispheric ischemia in the unanesthetized rat. Stroke 10:267-272.
    • (1979) Stroke , vol.10 , pp. 267-272
    • Pulsinelly, W.A.1    Brierley, F.B.2
  • 43
    • 0024270562 scopus 로고
    • The role of short-term hypobaric hypoxia in prevention of disorders of the cerebral circulation in rats during acoustic stress
    • Ryasina, T. V., Koshelev, V. B., Krushinsky, A. L., Lozhnikova, S. M., and Lyudkovskaya, I. G. (1988). The role of short-term hypobaric hypoxia in prevention of disorders of the cerebral circulation in rats during acoustic stress. Brain Res. 471:153-156.
    • (1988) Brain Res. , vol.471 , pp. 153-156
    • Ryasina, T.V.1    Koshelev, V.B.2    Krushinsky, A.L.3    Lozhnikova, S.M.4    Lyudkovskaya, I.G.5
  • 44
    • 0024153902 scopus 로고
    • Acidosis and ischemic brain damage
    • Siesjo, B. K. (1988). Acidosis and ischemic brain damage. Neurochem. Pathol. 9:31-88.
    • (1988) Neurochem. Pathol. , vol.9 , pp. 31-88
    • Siesjo, B.K.1
  • 45
    • 0029958751 scopus 로고    scopus 로고
    • Immunomodulating effects of carnosine in in vivo and in vitro experiments
    • in Russian
    • Stvolinsky, S. L., Sousa, S., Pontesh, E., Sergienko, V., and Boldyrev, A. A. (1996). Immunomodulating effects of carnosine in in vivo and in vitro experiments. Membr. Cell. Biol. 10:323-330 (in Russian).
    • (1996) Membr. Cell. Biol. , vol.10 , pp. 323-330
    • Stvolinsky, S.L.1    Sousa, S.2    Pontesh, E.3    Sergienko, V.4    Boldyrev, A.A.5
  • 46
    • 0026094240 scopus 로고
    • The antioxidant properties of a novel zinc-carnosine chelate compound, N-(3-aminopropionyl)-L-histidinatozic
    • Yoshikawa, T., Naito, Y., Tanigawa, T., Yoneta, T., and Condo, M. (1991). The antioxidant properties of a novel zinc-carnosine chelate compound, N-(3-aminopropionyl)-L-histidinatozic. Biochim. Biophys. Acta 1115:15-22.
    • (1991) Biochim. Biophys. Acta , vol.1115 , pp. 15-22
    • Yoshikawa, T.1    Naito, Y.2    Tanigawa, T.3    Yoneta, T.4    Condo, M.5
  • 47
    • 0028088304 scopus 로고
    • Prolonged production of hydroxyl radical in rat hippocampus after brain ischemia-reperfusion is decreased by 21-aminosteroids
    • Zhang, J., and Piantodosi, C. A. (1994). Prolonged production of hydroxyl radical in rat hippocampus after brain ischemia-reperfusion is decreased by 21-aminosteroids. Neurosci. Lett. 177:127-130.
    • (1994) Neurosci. Lett. , vol.177 , pp. 127-130
    • Zhang, J.1    Piantodosi, C.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.