Degradation of hydroxypropylcellulose by Rhizomucor: Effects on release from theophylline-hydroxypropylcellulose tablets

International Journal of Pharmaceutics

Volumn 180, Issue 1, 1999, Pages 105-111

  Alvarez Lorenzo, C ^a   Duro, R ^a   Gomez Amoza J L ^a   Martinez Pacheco R ^a   Souto, C ^a   Concheiro, A ^a  

^a Universidade de Santiago de Compostela   (Spain)

Author keywords

Hydrophilic matrices; Hydroxypropylcellulose; Microbiological contamination of excipients; Rhizomucor; Stability of cellulose ethers

Indexed keywords

HYDROXYPROPYLCELLULOSE; KLUCEL M BC; KLUCEL M BJ; KLUCEL M JD; KLUCEL MF; NISSO H BJ; NISSO H JE; THEOPHYLLINE; UNCLASSIFIED DRUG;

ARTICLE; BIODEGRADATION; DRUG RELEASE; DRUG STABILITY; IN VITRO STUDY; MOISTURE; PARTICLE SIZE; PH; PRIORITY JOURNAL; RHIZOMUCOR; STORAGE;

CELLULOSE; DRUG STABILITY; DRUG STORAGE; HYDROGEN-ION CONCENTRATION; RHIZOMUCOR; TABLETS; THEOPHYLLINE;

EID: 0033034919     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(98)00410-4     Document Type: Article

References (29)

1. Acquier R., Belhani F., Maillols H., Delonca H. Hydroxypropylcellulose et libération des principes actifs. I. Influence de la mase moléculaire du polymère et de sa concentration. STP Pharma Sci. 2:1992;469-474.
2. Arai M., Sakamoto R., Murao S. Enzymatic properties of two Avicelases from Aspergillus aculeatus No. F-50. Agric. Biol. Chem. 51:1987;627-633.
3. Banker G., Peck G., Williams E., Taylor D., Pirakitikulr P. Microbiological considerations of polymer solutions used in aqueous film coating. Drug Dev. Ind. Pharm. 8:1982;41-51.
4. Bardet L., Alain M Caractérisation physicochimique d'un haut polymère d'acide acrylique utilisé en pharmacie. II. Détermination de la masse moléculaire. Trav. Soc. Pharm. Montpellier. 35:1975;263-272.
5. Beveridge E.G. Microbial spoilage and preservation of pharmaceutical products. Hugo W.B., Russell A.D. Pharmaceutical Microbiology. 1992;Blackwell, Oxford.
6. Blair T.C., Buckton G., Bloomfield F. On the mechanism of kill of microbial contaminants during tablet compression. Int. J. Pharm. 72:1991;111-115.
7. British Pharmacopoeia. 1998;Her Majesty's Stationary Office, London.
8. Dahl T.C., Calderwood T., Bormeth A., Trimble K., Piepmeier E. Influence of physico-chemical properties of hydroxypropylmethylcellulose on naproxen release from sustained release matrix tablets. J. Control. Release. 14:1990;1-10.
9. Dawson C., Belloch C., García-López M.D., Uruburu F. Spanish Type Culture Collection. Catalogue of Strains. 3rd ed. 1990;University of Valencia, Valencia.
10. De la Rosa M.C., Medina M.R., Vivar C. Microbiological quality of pharmaceutical raw materials. Pharm. Acta Helv. 70:1995;227-232.
11. Doelker E. Cellulose derivatives. Adv. Polym. Sci. 107:1993;200-265.
12. El-Naghy M.A., El-Katany M.S., Attia A.A. Degradation of cellulosic materials by Sporotrichum thermophile culture filtrate for sugar production. Int. Biodeterioration. 27:1991;75-86.
13. European Pharmacopoeia. 2nd ed. 1995;Maisonneuve, Sainte-Ruffine.
14. Handbook of Pharmaceutical Excipients. 2nd ed. 1994;Americal Pharmaceutical Association-The Pharmaceutical Press, London.
15. Higuchi T. Theoretical analysis of rate of release of solid drugs dispersed in solid matrices. J. Pharm. Sci. 52:1963;1145-1149.
16. 13C n.m.r. studies of the thermal behaviour of aqueous solutions of cellulose ethers. Polymer. 33:1992;4087-4094.
17. Jones B.E., Williamson I.P., Gooday G.W. Sex pheromones in mucor. O′Day D.H., Horgen P.A. Sexual Interactions in Eukaryotic Microbes. 1981;Academic Press, New York.
18. Kasulke U., Philipp B., Polter E. Zur Wechselwirkung zwischen einer Penicillium-Cellulase und wasserlöslichen Cellulosederivaten. Acta Biotechnol. 7:1987;147-155.
19. Larone D.H. Medically Important Fungi (A Guide to Identification). 1995;ASM Press, Washington, DC.
20. 13C-NMR spectral and related studies on the distribution of substituents in o-(2-hydroxypropyl)cellulose. Carbohydr. Res. 106:1982;1-19.
21. Ma Z., Zhang W., Li Z. Study on the characterization of distribution of substituents along the chain of carboxymethylcellulose. Chin. J. Polymer Sci. 7:1989;45-53.
22. Masková H.P., Vasilyeva L.V., Kofronová O., Kunc F. Microflora participating in the decomposition of carboxymethylcellulose continuously added to the soil. Folia Microbiol. 33:1988;482-490.
23. Mitchell K., Ford J.L., Armstrong D.J., Elliott P.N.C., Rostron C., Hogan J.E. The influence of substitution type on the performance of methylcellulose and hydroxypropylmethylcellulose in gels and matrices. Int. J. Pharm. 100:1993;143-154.
24. 13C-N.M.R. spectroscopy of cellulose ethers. Carbohydr. Res. 57:1977;39-49.
25. Shambe T., Ejembi O. Production of amylase and cellulase: degradation of starch and carboxymethylcellulose by extracellular enzymes from four fungal species. Enzyme Microb. Technol. 9:1987;308-312.
26. Singh A., Hayashi K. Microbial cellulases: protein architecture, molecular properties and biosynthesis. Advances in Applied Microbiology. 40:1995;Academic Press, San Diego.
27. United States Pharmacopeia 23-The National Formulary 18. 1995;United States Pharmacopeial Convention, Inc. Rockville.
28. Vázquez M.J., Pérez-Marcos B., Gómez-Amoza J.L., Martínez-Pacheco R., Souto C., Concheiro A. Influence of technological variables on release of drugs from hydrophilic matrices. Drug Dev. Ind. Pharm. 18:1992;1355-1375.
29. Wirick M.G., Waldman M.H. Solution properties of fractionated water-soluble hydroxypropyl cellulose. J. Appl. Polym. Sci. 14:1970;579-597.