Toxic effects, pharmacokinetics and clearance of saxitoxin, a component of paralytic shellfish poison (PSP), in cats

Toxicon

Volumn 37, Issue 3, 1999, Pages 447-464

  Andrinolo, Darío ^a   Michea, Luis F ^b   Lagos, Néstor ^a  

^a UNIVERSITY OF CHILE   (Chile)

^b UNIVERSIDAD DE LOS ANDES   (Chile)

Author keywords

[No Author keywords available]

Indexed keywords

DOBUTAMINE; SAXITOXIN;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE; CAT; CONTROLLED STUDY; DOSE RESPONSE; DRUG CLEARANCE; ELECTROCARDIOGRAM; HEART ARREST; HEMODYNAMICS; INTOXICATION; NONHUMAN; PRIORITY JOURNAL; SHELLFISH;

ANESTHESIA; ANIMALS; BLOOD PRESSURE; BLOOD-BRAIN BARRIER; CATS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOBUTAMINE; DRUG INTERACTIONS; ELECTROCARDIOGRAPHY; FLUORESCENCE; INJECTIONS, INTRAVENOUS; INULIN; MALE; MARINE TOXINS; SAXITOXIN; SENSITIVITY AND SPECIFICITY; SHELLFISH; TISSUE DISTRIBUTION;

EID: 0033034468     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0041-0101(98)00173-1     Document Type: Article

References (43)

1. Anderson, D.M. 1994. Red Tides. Scientific American, August, 52-58.
2. Benzer T.I., Raftery M.A. Partial characterization of a Tetrodotoxin-binding component from nerve membrane. Proc. Natl. Acad. Sci. U.S.A. 69:1972;3634-3637.
3. Borinson H.L., Culp W.J., Gonsalves S.F., McCartry L.E. Respiratory and circulatory effects of saxitoxin in the cerebrospinal fluid. Br. J. Pharmacol. 61:1977;679-686.
4. Borinson H.L., Culp W.J., Gonsalves S.F., McCarthy L.E. Central respiratory and circulatory depression caused by intravascular saxitoxin. Br. J. Pharmacol. 68:1980;301-309.
5. Catterall W.A., Morrow C.S., Hartshorne R.P. Neurotoxin binding to receptor sites associated with voltage-sensitive sodium channels in intact, lysed, and detergent-solubilized brain membranes. J. Biol. Chem. 254:1979;11379-11387.
6. Chang F.T., Benton B.J., Lenz R.A., Benedict R., Capacio B.R. Central and peripheral cardiorespiratory effects of saxitoxin (STX) in urethane-anaesthetized guinea-pigs. Toxicon. 31:1992;645-647.
7. Dobi S., Horvath A., Prinz G., Varnai F. Imported food poisoning caused by fish toxins (ciguatoxin). Orv. Retil. (Hungary). 131:1990;2201-2203.
8. Falconer I.R. Potential impact on human health of toxic cyanobacteria. Phycologia. 36:1996;6-11.
9. 3H -tetraethylammonium bromide in dogs and cats Am. J. Vet. Res. 46:1985;482-485.
10. Gambertoglio J.G., Amend W.J.C., Benet L.Z. Pharmacokinetics and bioavailability of prednisolone in healthy volunteers: A review. J. Pharmacokinet. Biopharm. 8:1980;1-5.
11. Gessner B.D., Bell P., Doucette G.J., Moczydlowski E., Poli M.A., Dolah F.V., Hall S. Hypertension and identification of toxin in human urine and serum following a cluster of mussel-associated paralytic shellfish poisoning outbreaks. Toxicon. 35:1997;711-722.
12. Guo X., Uehara A., Ravindran A., Bryant S.H., Hall S., Moczydlowski E. Kinetic basis for insensitivity to tetrodotoxin and saxitoxin in sodium channels of canine heart and denervated rat skeletal muscle. Biochemistry. 26:1987;7546-7556.
13. Hall, S., Strichartz, G., Moczydlowski, E., Ravindran, A., Reichardt, P.B. 1990. The saxitoxins; sources, chemistry, and pharmacology. In: Hall, A., Strichartz, G. (Eds.). Marine Toxins: Origin, Structure and Molecular Pharmacology, American Chemical Society Symposium, series 418, pp. 29-65. American Chemical Society, Washington, DC.
14. Hallegraeff G.M. A review of harmful algal blooms and their apparent global increase. Phycologia. 32:1993;79-99.
15. Henderson R., Ritchie J.M., Strichartz G.R. The Binding of labelled saxitoxin to the sodium channel in nerve membranes. J. Physiol. 235:1973;783-804.
16. 3H -Saxitoxinol metabolism and elimination in the rat Toxicon. 31:1993;905-908.
17. Hokama Y., Asahina A.Y., Hong T.W., Katsura K., Shang E., Miyahara J.T., Sweeney J.C., Stone R. Causative toxin(s) in the death of two Atlantic dolphins. J. Clin. Lab. Anal. 4:1990;474-478.
18. Iwasaki H. Growth physiology of red-tide microorganisms. Microbiol. Sci. 1:1984;48-52.
19. Jaggard P.J., Evans M.H. Administration of tetrodotoxin and saxitoxin into the lateral cerebral ventricle of the rabbit. Neuropharmacology. 14:1975;345-349.
20. Kao C.Y., Suzuki C.Y., Kleinahus T., Siegman M.J. Vasomotor and respiratory depressant actions of tetrodotoxin and saxitoxin. Arch. Int. Pharmacodyn. 165:1967;438-450.
21. Lagos, N., Compagnon, D., Seguel, M., Oshima, Y., 1996. Paralytic shellfish toxin composition: A quantitative analysis in chilean mussels and dinoflagellate. In: Yasumoto, T., Oshima, Y., Fukuyo Y. (Eds.), Harmfull and Toxic Algal Blooms, pp. 121-124. Intergovernmental Oceanographic Commission of UNESCO, Paris.
22. Lagos, N., Liberona, J.L., Andrinolo, D., Zagatto, P.A., Moraes, S.R., Azevedo, M.F.Q.S., 1997. First evidence of paralytic shellfish toxins in the freshwater cyanobacterium Cylindrospermopsis raciborskii isolated from Brasil. Abstracts, VIII International Conference on Harmfull Algae, VIGO, June 1997, pp. 115.
23. Long R.R., Sargent J.C., Hammer K. Paralytic shellfish poisoning: A case report and serial electrophysiologic observations. Neurology. 40:1990;1310-1311.
24. MMWR (United States), 1991. Paralytic shellfish poisoning-Massachusetts and Alaska, 1990, 40, 157-161.
25. Morris P.D., Campbell D.S., Taylor T.J. Clinical and epidemiological features of neurotoxic shellfish poisoning in North Carolina. Am. J. Public Health. 81:1991;471-474.
26. Moczydlowski, E., Uehara, A., Hall, S., 1986. Blocking pharmacology of batrachotoxin-activated Na-channels from rat skeletal muscle. In: Miller, C. (Ed.), Ion Channel Reconstitution, pp. 75-114. Plenum Press, New York.
27. Nagasawa J., Spiegelstein M.Y., Kao C.Y. Cardiovascular actions of Saxitoxin. The Journal of Pharmacology and Experimental Therapeutics. 178:1971;103-109.
28. Om A., Hess M.L. Inotropic therapy of the failing myocardium. Clin. Cardiol. 16:1993;5-14.
29. Onodera, H., Satake, M., Oshima, Y., Yasumoto, T., Carmichael, W.W., 1997. Detection of PSP toxins and six new saxitoxin analog in the freshwater filamentous cyanobacterium Lyngbya wollei. Abstracts, VIII International Conference on Harmfull Algae, VIGO, June 1997, p. 153.
30. Oshima Y. Post column derivatization liquid chromatographic method for paralytic shellfish toxins. Journal of AOAC International. 78:1995;528-532.
31. Oshima, Y., 1995b. Chemical and enzxymatic transformation of paralytic shellfish toxins in marine organisms. In: Lassus, P., Arzul, G., Erard-Le Denn, E., Gentien, P., Marcaillou-Le Baut, C. (Eds.), Harmful Marine Algal Blooms, pp. 475-480. Lavoisier Publishine, Intercept Ltd. Paris.
32. Schantz E.J., Ghazarossian V.E., Schones H.K., Strong F.M. The structure of Saxitoxin. Journal of the American Chemical Society. 97:1975;1238-1239.
33. Shimizu Y. Microalgal metabolites. Chem. Rev. 93:1993;1685-1698.
34. Shimizu Y., Yoshioka M. Transformation of paralytic shellfish toxins as demonstrated in scallop homogenates. Science. 212:1981;547-549.
35. Shimizu Y., Hsu Ch., Genenah A. Structure of Saxitoxin in solutions and stereochemistry of dihydrosaxitoxins. J. Am. Chem. Soc. 103:1981;605-609.
36. Sivonen K. Cyanobacterial toxins and toxin production. Phycologia. 36:1996;12-24.
37. Stafford R.G., Hines H.B. Methods for identification of saxitoxin in rat urine. Journal of Chromatography B. 657:1994;119-124.
38. Stafford R.G., Hines B.H. Urinary elimination of Saxitoxin after intravenous injection. Toxicon. 33:1995;1501-1510.
39. Strichartz G. Structural determinants of the affinity of saxitoxin sodium channel. J. Gen. Physiol. 84:1984;281-305.
40. Sullivan J.J., Iwaoka W.T., Liston J. Enzymatic transformation of PSP toxins in the littleneck clam (Protothaca staminea). Biochem. Biophys. Res. Commun. 114:1983;465-472.
41. Van Zwieten P.A. Receptor-mediated inotropic drugs. Eur. Heart J. 9(Suppl. H):1988;85-90.
42. Yasumoto T., Murata M. Marine toxins. Chem. Rev. 93:1993;1897-1909.
43. Yasumoto T., Fukui M., Sasaki K., Sugiyama K. Determination of marine toxins in foods. Journal of AOAC International. 78:1995;574-582.