Urokinase-type plasminogen activator and plasminogen activator inhibitor antigen in tissue extracts of paranasal sinus mucous membranes affected by chronic sinusitis and antrochoanal polyps

European Archives of Oto-Rhino-Laryngology

Volumn 256, Issue 5, 1999, Pages 237-241

  Sunagawa, M ^a   Kinjoh, K ^a   Nakamura, M ^a   Kosugi, T ^a  

^a UNIVERSITY OF THE RYUKYUS SCHOOL OF MEDICINE   (Japan)

Author keywords

Chronic sinusitis; Fibrinolytic enzymes; Plasminogen activator inhibitor 1; Sinus mucosa; Urokinase type plasminogen activator

Indexed keywords

ANTIGEN; BUFFER; PLASMIN; PLASMINOGEN ACTIVATOR INHIBITOR 1; TISSUE EXTRACT; UROKINASE;

ARTICLE; CHRONIC SINUSITIS; CLINICAL ARTICLE; EXTRACTION; HUMAN; HUMAN TISSUE; NOSE MUCOSA; NOSE POLYP; PARANASAL SINUS; PH; PRIORITY JOURNAL;

EID: 0033034119     PISSN: 09374477     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004050050149     Document Type: Article

References (18)

1. Bajpai A, Baker JB (1985) Cryptic urokinase binding sites on human foreskin fibroblasts. Biochem Biophys Res Commun 133:475-482
2. Danø K, Andreasen PA, Grøndahl-Hansen J, Kristensen P, Nielsen LS, Skriver L (1985) Plasminogen activators, tissue degradation and cancer. Adv Cancer Res 44:139-266
3. Kosugi T, Morimitsu T, Matsuo O, Mihara H (1979) A protease-antiprotease system in antrochoanal polyp. 1. Evidence for the existence of proactivator. Arch Otorhinolaryngol 225:97-102
4. Kosugi T, Kinjo K, Takagi I, Sueno K, Noda Y, Mihara H (1984) The role of fibrinolytic enzymes in inflammation and paranasal mucous membrane. Rhinology 22:119-123
5. 2-macroglobulin receptor mediated cellular uptake of pro-urokinase. J Biol Chem 268:21862-21867
6. Loskutoff DJ, Edington TS (1977) Synthesis of a fibrinolytic activator and inhibitor by endothelial cells. Proc Natl Acad Sci USA 74:3903-3907
7. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ (1951) Protein measurement with the Folin phenol reagent. J Biol Chem 193:265-275
8. Pappot H, Gårdsvoll H, Rømer J, Pedersen AN, Grøndahl-Hansen J, Pyke C, Brünner N (1995) Plasminogen activator inhibitor type 1 in cancer: Therapeutic and prognostic implications. Biol Chem Hoppe-Seyler 376:259-267
9. Plow EF, Freaney DE, Plescia J, Miles LA (1986) The plasminogen system and cell surfaces: Evidence for plasminogen and urokinase receptors on the same cell type. J Cell Biol 103:2411-2420
10. Saksela O, Rifkin DB (1988) Cell-associated plasminogen activator: Regulation and physiological function. Annu Rev Cell Biol 4:93-126
11. Sasaki Y, Okamoto S, Ohwada K, Nishibata T (1959) Some observations on a remarkable fibrinolytic activity in the extract of nasal tissue and related tissue. Keio J Med 8:235-246
12. Strickland DK, Kounnas MZ, Williams SE, Argraves WS (1994) LDL receptor-related protein (LRP): A multiligand receptor. Fibrinolysis 8:204-215
13. Sunagawa M, Huang G-W, Nakamura M, Kosugi T (1997) The concentration of u-PA and PAI-1 antigen in tissue extracts of nasopharyngeal carcinoma. Eur Arch Otorhinolaryngol 354:277-280
14. Van Mourik JA, Lawrence DA, Loskutoff DJ (1984) Purification of an inhibitor of plasminogen activator (antiactivator) synthesized by endothelial cells. J Biol Chem 259:14914-14921
15. Vassalli JD, Baccino D, Belin D (1985) A cellular binding site for the Mr 55,000 form of the human plasminogen activator, urokinase. J Cell Biol 100:86-92
16. Vassalli JD, Sappino AP, Belin D (1991) The plasminogen activator/plasmin system. J Clin Invest 88:1067-1072
17. Yamashiro Y, Nakamura M, Huang G-W, Kosugi T (1992) Presence of urokinase type plasminogen activator (u-PA) in tissue extracts of antrochoanal polyp. Laryngoscope 102:1049-1052
18. Yamashiro Y, Nakamura M, Huang G-W, Kosugi T (1993) Fibrin binding, fibrinolytic and fibrinogenolytic activity of plasminogen activator derived from the paranasal mucous membrane of humans. Laryngoscope 103:197-202