Tissue inhibitors of metalloproteinases: Role in liver fibrosis and alcoholic liver disease

Alcoholism: Clinical and Experimental Research

Volumn 23, Issue 5, 1999, Pages 940-943

  Arthur, Michael J P ^a,b   Iredale, John P ^a   Mann, Derek A ^a  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^b SOUTHAMPTON GENERAL HOSPITAL   (United Kingdom)

Author keywords

Cirrhosis; Collagenase; Matrix Degradation; Matrix Metalloproteinase

Indexed keywords

COLLAGEN TYPE 1; COLLAGEN TYPE 3; COLLAGENASE; MATRIX METALLOPROTEINASE; MATRIX PROTEIN; TISSUE INHIBITOR OF METALLOPROTEINASE;

ALCOHOL LIVER DISEASE; CONFERENCE PAPER; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; LIVER FIBROSIS; PRIORITY JOURNAL; STELLATE CELL;

ANIMALIA;

EID: 0033033426     PISSN: 01456008     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1530-0277.1999.tb04208.x     Document Type: Conference Paper

References (28)

1. Murphy G, Cawston TE, Reynolds JJ (1981) An inhibitor of collagenase from human amniotic fluid. Biochem J 195:167-170.
2. Stetler-Stevenson WG, Krutzsch HC, Liotta LA (1989) Tissue inhibitor of metalloproteinase (TIMP-2). J Biol Chem 264:17374-17378.
3. Pavloff N, Staskus PW, Kishnani NS, Hawkes SP (1992) A new nibitor of metalloproteinases from Chicken-ChIMP-3 - A 3rd member of the TIMP family. J Biol Chem 267:17321-17326.
4. Leco KJ, Apte SS, Taniguchi GT, et al (1997) Murine tissue inhibitor of metalloproteinases-4 (TIMP-4): cDNA isolation and expression in adult mouse tissues. FEBS Lett 401:213-217.
5. Docherty AJP, Lyons A, Smith BJ, et al (1985) Sequence of human tissue inhibitor of metalloproteinases and its identity to erythroidpotentiating activity. Nature 318:66-69.
6. Bodden MK, Harber GJ, Birkedalhansen B, et al (1994) Functional domains of human TIMP-1 (tissue inhibitor of metalloproteinases). J Biol Chem 269:18943-18952.
7. Edwards DR, Rocheleau H, Sharma RR, et al (1992) Involvement of AP1 and PEA3 binding sites in the regulation of murine tissue inhibitor of metalloproteinases-1 (TIMP-1) transcription. Biochim Biophys Acta 1171:41-55.
8. Bugno M, Graeve L, Gatsios P, et al (1995) Identification of the interleukin-6/oncostatin M response element in the rat tissue inhibitor of metalloproteinases-1 (TIMP-1) promoter. Nucleic Acid Res 23:5041-5047.
9. Goldberg GI, Manner BL, Grant GA, Eisen AZ, Wilhelm S, He C (1989) Human 72-kilodalton type IV collagenase forms a complex with a tissue inhibitor of metalloproteases designated TIMP-2. Proc Natl Acad Sci USA 86:8207-8211.
10. Howard EW, Banda MJ (1991) Binding of tissue inhibitor of metalloproteinases 2 to two distinct sites on human 72-kDa gelatinase. J Biol Chem 266:17972-17977.
11. Fridman R, Fuerst TR, Bird RE, et al (1992) Domain structure of human 72-kDa gelatinase type-IV collagenase characterization of proteolytic activity and identification of the tissue inhibitor of metalloproteinase-2 (TIMP-2) binding regions. J Biol Chem 267:15398-15405.
12. Ward RV, Atkinson SJ, Slocombe PM, Docherty AJP, Reynolds JJ, Murphy G (1991) Tissue inhibitor of metalloproteinases-2 inhibits the activation of 72 kDa progelatinase by fibroblast membranes. Biochim Biophys Acta 1079:242-246.
13. Howard EW, Bullen EC, Banda MJ (1991) Regulation of the autoactivation of human 72-kDa progelatinase by tissue inhibitor of metalloproteinases-2*. J Biol Chem 266:13064-13069.
14. Strongin AY, Collier I, Bannikov G, Marmer BL, Grant GA, Goldberg GI (1995) Mechanism of cell surface activation of 72-kDa type IV collagenase - Isolation of the activated form of the membrane metalloprotease. J Biol Chem 270:5331-5338.
15. Leco KJ, Khokha R, Pavloff N, Hawkes SP, Edwards DR (1994) Tissue inhibitor of metalloproteinases-3 (Timp-3) is an extracellular matrix-associated protein with a distinctive pattern of expression in mouse cells and tissues. J Biol Chem 269:9352-9360.
16. Apte SS, Mattei MG, Olsen BR (1994) Cloning of the cDNA encoding human tissue inhibitor of metalloproteinases-3 (Timp-3) and mapping of the Timp3 gene to chromosome 22. Genomics 19:86-90.
17. Iredale JP, Benyon RC, Arthur MJP, et al (1996) Tissue inhibitor of metalloproteinase-1 messenger RNA expression is enhanced relative to interstitial collagenase messenger RNA in experimental liver injury and fibrosis. Hepatology 24:176-184.
18. Iredale JP, Murphy G, Hembry RM, Friedman SL, Arthur MJP (1992) Human hepatic lipocytes synthesize tissue inhibitor of metalloproteinases-1 (TIMP-1): Implications for regulation of matrix degradation in liver. J Clin Invest 90:282-287.
19. Benyon RC, Iredale JP, Goddard S, Winwood PJ, Arthur MJP (1996) Expression of tissue inhibitor of metalloproteinases-1 and -2 in increased in fibrotic human liver. Gastroenterology 110:821-831.
20. Iredale JP, Goddard S, Murphy G, Benyon RC, Arthur MJP (1995) Tissue inhibitor of metalloproteinase-1 and interstitial collagenase expression in autoimmune chronic active hepatitis and activated human hepatic lipocytes. Clin Sci 89:75-81.
21. Iredale JP, Benyon RC, Pickering J, et al (1998) Mechanisms of spontaneous resolution of rat liver fibrosis: Hepatic stellate cell apoptosis and reduced hepatic expression of metalloproteinase inhibitors. J Clin Invest 102:538-549.
22. Bahr MJ, Fowler AV, Arthur MJP, Mann DA (1997) Cell type-specific regulation of the tissue inhibitor of metalloproteinases (TIMP)-1 gene promoter in hepatic stellate cells. J Hepatol 26(Suppl. 1):66.
23. Logan SK, Garabedian MJ, Campbell CE, Werb Z (1996) Synergjstic transcriptional activation of the tissue inhibitor of metalloproteinases-1 promoter via functional interaction of ap-1 and ets-1 transcription factors. J Biol Chem 271:774-782.
24. Roeb E, Rosejohn S, Erren A, et al (1995) Tissue inhibitor of metalloproteinases-2 (TIMP-2) in rat liver cells is increased by lipopolysaccharide and prostaglandin E(2). FEBS Lett 357:33-36.
25. Roeb E, Graeve L, Hoffmann R, Decker K, Edwards DR, Heinrich PC (1993) Regulation of tissue inhibitor of metalloproteinases-1 gene expression by cytokines and dexamethasone in rat hepatocyte primary cultures. Hepatology 18:1437-1442.
26. Roeb E, Graeve L, Mullberg J, Matern S, Rosejohn S (1994) TIMP-1 protein expression is stimulated by IL-1 beta and IL-6 in primary rat hepatocytes. FEBS Lett 349:45-49.
27. Herbst H, Wege T, Milani S, et al (1997) Tissue inhibitor of metalloproteinase-1 and -2 RNA expression in rat and human liver fibrosis. Am J Pathol 150:1647-1659.
28. Li JJ, Rosman AS, Leo MA, Nagai Y, Lieber CS (1994) Tissue inhibitor of metalloproteinase is increased in the serum of precirrhotic and cirrhotic alcoholic patients and can serve as a marker of fibrosis. Hepatology 19:1418-1423.