From a static to a dynamic concept of risk: The circadian epidemiology of cardiovascular events

Chronobiology International

Volumn 16, Issue 1, 1999, Pages 33-49

  Portaluppi, Francesco ^a   Manfredini, Roberto ^a   Fersini, Carmelo ^a  

^a UNIVERSITY OF FERRARA   (Italy)

Author keywords

Arrhythmia; Blood pressure; Circadian Rhythm; Hemorrhage; Myocardial infarction; Myocardial ischemia; Risk factors Stroke; Sudden cardiac death; Thrombosis; Time factors

Indexed keywords

CARDIOVASCULAR DISEASE; CHRONOBIOLOGY; CIRCADIAN RHYTHM; DISEASE PREDISPOSITION; HEART INFARCTION; HEART MUSCLE ISCHEMIA; HUMAN; HUMAN TISSUE; PATHOPHYSIOLOGY; PERIODICITY; PROGNOSIS; RISK ASSESSMENT; SHORT SURVEY; SUDDEN DEATH; TREATMENT OUTCOME;

EID: 0033033076     PISSN: 07420528     EISSN: None     Source Type: Journal    
DOI: 10.3109/07420529908998710     Document Type: Short Survey

References (160)

1. Alboni P, degli Uberti E, Codeca L, et al. 1982. Circadian variations of sinus rate in subjects with sinus node dysfunction. Chronobiologia. 9:173-183.
2. Ameriso SF, Mohler JG, Suarez M, et al. 1994. Morning reduction of cerebral vasomotor reactivity. Neurology. 44:1907-1909.
3. Andreotti F, Davies GJ, Hackett DR, et al. 1988. Major circadian fluctuations in fibrinolytic factors and possible relevance to time of onset of myocardial infarction, sudden cardiac death and stroke. Am J Cardiol. 62:635-637.
4. Andreotti F, Kluft C. 1991. Circadian variation of fibrinolytic activity in blood. Chronobiol Int. 8:336-351.
5. Andrews TC, Fenton T, Toyosaki N, et al. 1993. Subsets of ambulatory myocardial ischemia based on heart rate activity. Circadian distribution and response to anti-ischemic medication. The Angina and Silent Ischemia Study Group (ASIS). Circulation. 88:92-100.
6. Angleton P, Chandler WL, Schmer G. 1989. Diurnal variation of tissue-type plasminogen activator and its rapid inhibitor (PAI-1). Circulation. 79:101-106.
7. Araki H, Koiwaya Y, Nakagaki O, et al. 1983. Diurnal distribution of ST-segment elevation and related arrhythmias in patients with variant angina: a study by ambulatory ECG monitoring. Circulation. 67:995-1000.
8. Arboix A, Marti-Vilalta JL. 1990. Acute stroke and circadian rhythm [letter]. Stroke. 21: 826.
9. Argentino C, Toni D, Rasura M, et al. 1990. Circadian variation in the frequency of ischemic stroke. Stroke. 21:387-389.
10. Arntz HR, Willich SN, Oeff M, et al. 1993. Circadian variation of sudden cardiac death reflects age-related variability in ventricular fibrillation. Circulation. 88:2284-2289.
11. Aronow WS, Ahn C. 1993. Circadian variation of primary cardiac arrest or sudden cardiac death in patients aged 62 to 100 years (mean 82). Am J Cardiol. 71:1455-1456.
12. Aschoff J, Wever R. 1976. Human circadian rhythms: a multioscillatory system. Fed Proc. 35:2326-2332.
13. Ashkar E. 1979. Twenty-four-hour pattern of circulation by radiotelemetry in the unrestrained dog. Am J Physiol. 236:R231-R236.
14. Aslanian NL. 1990. Chronobiological aspects of ischemic heart disease. Prog Clin Biol Res. 341B:583-592.
15. Athanassiadis D, Draper GJ, Honour AJ, et al. 1969. Variability of automatic blood pressure measurements over 24 hour periods. Clin Sci. 36:147-156.
16. Barash D, Silverman RA, Gennis P, et al. 1989. Circadian variation in the frequency of myocardial infarction and death associated with acute pulmonary edema. J Emerg Med. 7:119-121.
17. Behar S, Halabi M, Reicher-Reiss H, et al. 1993. Circadian variation and possible external triggers of onset of myocardial infarction. SPRINT Study Group. Am J Med. 94:395-400.
18. Behar S, Reicher-Reiss H, Goldbourt U, et al. 1991. Circadian variation in pain onset in unstable angina pectoris. Am J Cardiol. 67:91-93.
19. Benhorin J, Banai S, Moriel M, et al. 1993. Circadian variations in ischemic threshold and their relation to the occurrence of ischemic episodes. Circulation. 87:808-814.
20. Brezinski DA, Tofler GH, Muller JE, et al. 1988. Morning increase in platelet aggregability. Association with assumption of the upright posture. Circulation. 78:35-40.
21. Bridges AB, McLaren M, Scott NA, et al. 1993. Circadian variation of tissue plasminogen activator and its inhibitor, von Willebrand factor antigen, and prostacyclin stimulating factor in men with ischaemic heart disease. Br Heart J. 69:121-124.
22. Bridges AB, Scott NA, McNeill GP, et al. 1992. Circadian variation of white blood cell aggregation and free radical indices in men with ischaemic heart disease. Eur Heart J. 13:1632-1636.
23. Broadhurst P, Brigden G, Dasgupta P, et al. 1990. Ambulatory intra-arterial blood pressure in normal subjects. Am Heart J. 120:160-166.
24. Christ JE, Hoff HE. 1975. An analysis of the circadian rhythmicity of atrial and ventricular rates in complete heart block. J Electrocardiol. 8:69-72.
25. Clair WK, Wilkinson WE, McCarthy EA, et al. 1993. Spontaneous occurrence of symptomatic paroxysmal atrial fibrillation and paroxysmal supraventricular tachycardia in untreated patients. Circulation. 87:1114-1122.
26. Coccagna G, Mantovani M, Brignani F, et al. 1971. Laboratory note. Arterial pressure changes during spontaneous sleep in man. Electroencephalogr Clin Neurophysiol. 31:277-281.
27. Cohen MC, Rohtla KM, Lavery CE, et al. 1997. Meta-analysis of the morning excess of acute myocardial infarction and sudden cardiac death. Am J Cardiol. 79:1512-1516.
28. Conchonnet P, Decousus H, Perpoint B. 1990. Morning hypercoagulability in man. Annu Rev Chronopharmacol. 7:165-168.
29. Cugini P, Di Palma L, Battisti P, et al. 1990. Ultradian, circadian and infradian periodicity of some cardiovascular emergencies. Am J Cardiol. 66:240-243.
30. Czeisler CA, Weitzman ED, Moore-Ede MC, et al. 1980. Human sleep: its duration and organization depend on its circadian phase. Science. 210:1264-1267.
31. Czeisler CA, Zimmerman JC, Ronda JM, et al. 1980. Timing of REM sleep is coupled to the circadian rhythm of body temperature in man. Sleep. 2:329-346.
32. Dabrowska B, Feltynowski T, Wocial B, et al. 1990. Effect of removal of phaeochromocytoma on diurnal variability of blood pressure, heart rhythm and excretion of catecholamines. J Hum Hypertens. 4:397-399.
33. Deedwania PC. 1996. Hemodynamic changes as triggers of cardiovascular events. Cardiol Clin. 14:229-238.
34. Degaute JP, Van Cauter E, van de Borne P, et al. 1994. Twenty-four-hour blood pressure and heart rate profiles in humans. A twin study. Hypertension. 23:244-253.
35. Degaute JP, van de Borne P, Linkowski P, et al. 1991. Quantitative analysis of the 24-hour blood pressure and heart rate patterns in young men. Hypertension. 18:199-210.
36. de Leonardis V, De Scalzi M, Vergassola R, et al. 1987. Circadian variations of heart rate and premature beats in healthy subjects and in patients with previous myocardial infarction. Chronobiol Int. 4:283-289.
37. Ehrly AM, Jung G. 1973. Circadian rhythm of human blood viscosity. Biorheology. 10: 577-583.
38. Elliott WJ. 1998. Circadian variation in the timing of stroke onset: a meta-analysis. Stroke. 29:992-996.
39. Fahn S. 1981. Fluctuations of disability in Parkinson's disease: pathophysiological aspects. In: Marsden CD, Fahn S, eds. Movement disorders. London: Buttersworth Scientific, pp. 123-145.
40. Fallo F, Fanelli G, Cipolla A, et al. 1994. 24-Hour blood pressure profile in Addison's disease. Am J Hypertens. 7:1105-1109.
41. Fearnley GR, Balmforth G, Fearnley E. 1957. Evidence of a diurnal fibrinolytic rhythm with a simple method of measuring natural fibrinolysis. Clin Sci. 16:645-650.
42. Fersini C, Manfredini R, Manfredini F, et al. 1987. Chronobiologic aspects of recurrent transient ischemic attack. Prog Clin Biol Res. 227B:167-171.
43. Floras JS, Jones JV, Johnston JA, et al. 1978. Arousal and the circadian rhythm of blood pressure. Clin Sci Mol Med. 4(suppl 1):S395-S397.
44. Fox K, Mulcahy D, Keegan J, et al. 1989. Circadian patterns of myocardial ischemia. Am Heart J. 118:1084-1087.
45. Fujita M, Araie E, Yamanishi K, et al. 1993. Circadian variation in the success rate of intracoronary thrombolysis for acute myocardial infarction. Am J Cardiol. 71: 1369-1371.
46. Fujita M, Franklin D. 1987. Diurnal changes in coronary blood flow in conscious dogs. Circulation. 76:488-491.
47. Gallerani M, Manfredini R, Graziani R, et al. 1994. Sudden death in diabetic subjects: evidence for a peculiar circadian variation in occurrence. Panminerva Med. 36: 134-137.
48. Gallerani M, Manfredini R, Ricci L, et al. 1993a. Chronobiological aspects of acute cerebrovascular diseases. Acta Neurol Scand. 87:482-487.
49. Gallerani M, Manfredini R, Ricci L, et al. 1993b. Circadian variation in the onset of acute myocardial infarction: lack of an effect due to age and sex. J Int Med Res. 21:158-160.
50. Gallerani M, Manfredini R, Ricci L, et al. 1993c. Sudden death may show a circadian time of risk depending on its anatomo-clinical causes and age. Jpn Heart J. 34: 729-739.
51. Gallerani M, Trappella G, Manfredini R, et al. 1994. Acute intracerebral haemorrhage: circadian and circannual patterns of onset. Acta Neurol Scand. 89:280-286.
52. Gillis AM, Peters RW, Mitchell LB, et al. 1992. Effects of left ventricular dysfunction on the circadian variation of ventricular premature complexes in healed myocardial infarction. Am J Cardiol. 69:1009-1014.
53. Gilpin EA, Hjalmarson A, Ross J. 1990. Subgroups of patients with atypical circadian patterns of symptom onset in acute myocardial infarction. Am J Cardiol. 66:7G-11G.
54. Globus MY, Ginsberg MD, Harik SI, et al. 1987. Role of dopamine in ischemic striatal injury: metabolic evidence. Neurology. 37:1712-1719.
55. Goldberg RJ, Brady P, Muller JE, et al. 1990. Time of onset of symptoms of acute myocardial infarction. Am J Cardiol. 66:140-144.
56. Gordon RD, Wolfe LK, Island DP, et al. 1966. A diurnal rhythm in plasma renin activity in man. J Clin Invest. 45:1587-1592.
57. Gould BA, Raftery EB. 1991. Twenty-four-hour blood pressure control: an intraarterial review. Chronobiol Int. 8:495-505.
58. Grimaudo V, Hauert J, Bachmann F, et al. 1988. Diurnal variation of the fibrinolytic system. Thromb Haemost. 59:495-499.
59. Hansen O, Johansson BW, Gullberg B. 1992. Circadian distribution of onset of acute myocardial infarction in subgroups from analysis of 10,791 patients treated in a single center. Am J Cardiol. 69:1003-1008.
60. Hansen O, Johansson BW, Gullberg B. 1993. The clinical outcome of acute myocardial infarction is related to the circadian rhythm of myocardial infarction onset. Angiology. 44:509-516.
61. Haus E, Cusulos M, Sackett-Lundeen L, et al. 1990. Circadian variations in blood coagulation parameters, alpha-antitrypsin antigen and platelet aggregation and retention in clinically healthy subjects. Chronobiol Int. 7:203-216.
62. Hausmann D, Lichtlen PR, Nikutta P, et al. 1991. Circadian variation of myocardial ischemia in patients with stable coronary artery disease. Chronobiol Int. 8:385-398.
63. Hjalmarson A, Gilpin EA, Nicod P, et al. 1989. Differing circadian patterns of symptom onset in subgroups of patients with acute myocardial infarction. Circulation. 80: 267-275.
64. Hossmann V. 1971. Circadian changes of blood pressure and stroke. In: Zulch KJ, ed. Cerebral circulation and stroke. Berlin: Springer Verlag, pp. 203-208.
65. Huber K, Rose D, Resch I, et al. 1989. Circadian fluctuations of plasma levels of tissue plasminogen activator antigen and plasminogen activator inhibitor activity. Fibrinolysis. 3:41-43.
66. Imai Y, Abe K, Miura Y, et al. 1988. Hypertensive episodes and circadian fluctuations of blood pressure in patients with phaeochromocytoma: studies by long-term blood pressure monitoring based on a volume-oscillometric method. J Hypertens. 6:9-15.
67. Imai Y, Abe K, Sasaki S, et al. 1989. Exogenous glucocorticoid eliminates or reverses circadian blood pressure variations. J Hypertens. 7:113-120.
68. Imai Y, Abe K, Sasaki S, et al. 1988. Altered circadian blood pressure rhythm in patients with Cushing's syndrome. Hypertension. 12:11-19.
69. Imai Y, Abe K, Sasaki S, et al. 1992. Circadian blood pressure variation in patients with renovascular hypertension or primary aldosteronism. Clin Exp Hypertens [A]. 14: 1141-1167.
70. Irwin JM, McCarthy EA, Wilkinson WE, et al. 1988. Circadian occurrence of symptomatic paroxysmal supraventricular tachycardia in untreated patients. Circulation. 77: 298-300.
71. Isshiki T, Akatsuka N, Tsuneyoshi H, et al. 1986. Periodic fluctuation of blood pressure in a case of norepinephrine secreting extra-adrenal pheochromocytoma. Jpn Heart J. 27:437-442.
72. Jafri SM, Van Rollins M, Ozawa T, et al. 1992. Circadian variation in platelet function in healthy volunteers. Am J Cardiol. 69:951-954.
73. Johansson BB, Norrving B, Widner H, et al. 1990. Stroke incidence: circadian and circaseptan (about weekly) variations in onset. Prog Clin Biol Res. 341A:427-436.
74. Jovicic A, Mandic S. 1991.Circadian variations of platelet aggregability and fibrinolytic activity in healthy subjects. Thromb Res. 62:65-74.
75. King MJ, Zir LM, Kaltman AJ, et al. 1973. Variant angina associated with angiographically demonstrated coronary artery spasm and REM sleep. Am J Med Sci. 265: 419-422.
76. Kirby DA, Verrier RL. 1989. Differential effects of sleep stage on coronary hemodynamic function during stenosis. Physiol Behav. 45:1017-1020.
77. Kleiman NS, Schechtman KB, Young PM, et al. 1990. Lack of diurnal variation in the onset of non-Q wave infarction. Circulation. 81:548-555.
78. Kluft C, Jie AF, Rijken DC, et al. 1988. Daytime fluctuations in blood of tissue-type plasminogen activator (t-PA) and its fast-acting inhibitor (PAI-1). Thromb Haemost. 59:329-332.
79. Knutsson A. 1989. Shift work and coronary heart disease. Scand J Soc Med Suppl. 44: 1-36.
80. Kobrin I, Oigman W, Kumar A, et al. 1984. Diurnal variation of blood pressure in elderly patients with essential hypertension. J Am Geriatr Soc. 32:896-899.
81. Kohara K, Nishida W, Maguchi M, et al. 1995. Autonomic nervous function in non-dipper essential hypertensive subjects. Evaluation by power spectral analysis of heart rate variability. Hypertension. 26:808-814.
82. Kubota K, Sakurai T, Tamura J, et al. 1987. Is the circadian change in hematocrit and blood viscosity a factor triggering cerebral and myocardial infarction? [letter]. Stroke. 18:812-813.
83. Kupari M, Koskinen P, Leinonen H. 1990. Double-peaking circadian variation in the occurrence of sustained supraventricular tachyarrhythmias. Am Heart J. 120:1364-1369.
84. Kuwajima I, Mitani K, Miyao M, et al. 1995. Cardiac implications of the morning surge in blood pressure in elderly hypertensive patients: relation to arising time. Am J Hypertens. 1995;8:29-33.
85. Kuwajima I, Suzuki Y, Shimosawa T, et al. 1992. Diminished nocturnal decline in blood pressure in elderly hypertensive patients with left ventricular hypertrophy. Am Heart J. 123:1307-1311.
86. Labrecque G, Soulban G. 1991. Biological rhythms in the physiology and pharmacology of blood coagulation. Chronobiol Int. 8:361-372.
87. Lampert R, Rosenfeld L, Batsford W, et al. 1994. Circadian variation of sustained ventricular tachycardia in patients with coronary artery disease and implantable cardioverter-defibrillators. Circulation. 90:241-247.
88. Lanza GA, Cortellessa MC, Rebuzzi AG, et al. 1990. Reproducibility in circadian rhythm of ventricular premature complexes. Am J Cardiol. 66:1099-1106.
89. Lemmer B, Portaluppi F. 1997. Chronopharmacology of cardiovascular diseases. In: Redfern PH, Lemmer B, eds. Physiology and pharmacology of biological rhythms. Vol. 125. Heidelberg: Springer-Verlag, pp. 251-297.
90. Levine RL, Pepe PE, Fromm RE, et al. 1992. Prospective evidence of a circadian rhythm for out-of-hospital cardiac arrests. JAMA. 267:2935-2937.
91. Littler WA. 1979. Sleep and blood pressure: further observations. Am Heart J. 97:35-37.
92. Lucente M, Rebuzzi AG, Lanza GA, et al. 1988. Circadian variation of ventricular tachycardia in acute myocardial infarction. Am J Cardiol. 62:670-674.
93. Lugaresi E, Coccagna G, Mantovani M, et al. 1972. Some periodic phenomena arising during drowsiness and sleep in man. Electroencephalogr Clin Neurophysiol. 32: 701-705.
94. Mancia G, Ferrari A, Gregorini L, et al. 1983. Blood pressure and heart rate variabilities in normotensive and hypertensive human beings. Circ Res. 53:96-104.
95. Manfredini R, Gallerani M, Portaluppi F, et al. 1995. Circadian variation in the occurrence: of paroxysmal supraventricular tachycardia in clinically healthy subjects. Chronobiol Int. 12:55-61.
96. Marier JR, Price TR, Clark GL, et al. 1989. Morning increase in onset of ischemic stroke. Stroke. 20:473-476.
97. Marsh EE, Biller J, Adams HP, et al. 1990. Circadian variation in onset of acute ischemic stroke. Arch Neurol. 47:1178-1180.
98. Marshall J. 1977. Diurnal variation in occurrence of strokes. Stroke. 8:230-231.
99. Masuda T, Ogawa H, Miyao Y, et al. 1994. Circadian variation in fibrinolytic activity in patients with variant angina. Br Heart J. 71:156-161.
100. Millar-Craig MW, Bishop CN, Raftery EB. 1978. Circadian variation of blood-pressure. Lancet. 1:795-797.
101. Mulcahy D, Keegan J, Cunningham D, et al. 1988. Circadian variation of total ischaemic burden and its alteration with anti-anginal agents. Lancet. 2:755-759.
102. Muller JE, Ludmer PL, Willich SN, et al. 1987. Circadian variation in the frequency of sudden cardiac death. Circulation. 75:131-138.
103. Muller JE, Stone PH, Turi ZG, et al. 1985. Circadian variation in the frequency of onset of acute myocardial infarction. N Engl J Med. 313:1315-1322.
104. Musumeci V, Rosa S, Caruso A, et al. 1986. Abnormal diurnal changes in in-vivo platelet activation in patients with atherosclerotic diseases. Atherosclerosis. 60:231-236.
105. Nademanee K, Intarachot V, Josephson MA, et al. 1987. Circadian variation in occurrence of transient overt and silent myocardial ischemia in chronic stable angina and comparison with Prinzmetal angina in men. Am J Cardiol. 60:494-498.
106. Nowlin JB, Troyer WG, Collins WS. 1965. The association of nocturnal angina pectoris with dreaming. Ann Intern Med. 63:1040-1046.
107. O'Brien E, Sheridan J, O'Malley K. 1998. Dippers and nondippers. Lancet. 2:397.
108. Ogawa H, Yasue H, Oshima S, et al. 1989. Circadian variation of plasma fibrinopeptide A level in patients with variant angina. Circulation. 80:1617-1626.
109. Oishi S, Sasaki M, Ohno M, et al. 1988. Periodic fluctuation of blood pressure and its management in a patient with pheochromocytoma. Case report and review of the literature. Jpn Heart J. 29:389-399.
110. Palatini P, Penzo M, Racioppa A, et al. 1992. Clinical relevance of nighttime blood pressure and of daytime blood pressure variability. Arch Intern Med. 152:1855-1860.
111. Panza JA, Epstein SE, Quyyumi AA. 1991. Circadian variation in vascular tone and its relation to alpha-sympathetic vasoconstrictor activity. N Engl J Med. 325:986-990.
112. Pasqualetti P, Natali G, Casale R, et al. 1990. Epidemiological chronorisk of stroke. Acta Neurol Scand. 81:71-74.
113. Pell S, D'Alonzo CA. 1963. Acute myocardial infarction in a large industrial population: report of a 6-year study of 1,356 cases. JAMA. 185:831-838.
114. Peters RW, Muller JE, Goldstein S, et al. 1989. Propranolol and the morning increase in the frequency of sudden cardiac death (BHAT Study). Am J Cardiol. 63:1518-1520.
115. Petralito A, Mangiafico RA, Gibiino S, et al. 1982. Daily modifications of plasma fibrinogen, platelets aggregation, Howell's time, PTT, TT, and antithrombin II in normal subjects and in patients with vascular disease. Chronobiologia. 9:195-201.
116. Portaluppi F, Cortelli P, Avoni P, et al. 1994. Diurnal blood pressure variation and hormonal correlates in fatal familial insomnia. Hypertension. 23:569-576.
117. Quyyumi AA, Mockus L, Wright C, et al. 1985. Morphology of ambulatory ST segment changes in patients with varying severity of coronary artery disease. Investigation of the frequency of nocturnal ischaemia and coronary spasm. Br Heart J. 53: 186-193.
118. Quyyumi AA, Panza JA, Diodati JG, et al. 1992. Circadian variation in ischemic threshold. A mechanism underlying the circadian variation in ischemic events. Circulation 86:22-28.
119. Raeder EA. 1990. Circadian fluctuations in ventricular response to atrial fibrillation. Am J Cardiol. 66:1013-1016.
120. Raeder EA, Hohnloser SH, Graboys TB, et al. 1988. Spontaneous variability and circadian distribution of ectopic activity in patients with malignant ventricular arrhythmia. J Am Coll Cardiol. 12:656-661.
121. Rebuzzi AG. Lanza GA, Lucente M, et al. 1990. Circadian rhythm of ischemic episodes in patients with and without previous myocardial infarction. Prog Clin Biol Res. 341A:419-422.
122. Refinetti R, Menaker M. 1992. The circadian rhythm of body temperature. Physiol Behav. 51:613-637.
123. Ricci S, Celani MG, Vitali R, et al. 1992. Diurnal and seasonal variations in the occurrence of stroke: a community-based study. Neuroepidemiology. 11:59-64.
124. Rizzoni D, Muiesan ML, Montani G, et al. 1992. Relationship between initial cardiovascular structural changes and daytime and nighttime blood pressure monitoring. Am J Hypertens. 5:180-186.
125. Rocco MB. 1990. Timing and triggers of transient myocardial ischemia. Am J Cardiol. 66:18G-21G.
126. Rocco MB, Barry J, Campbell S, et al. 1987. Circadian variation of transient myocardial ischemia in patients with coronary artery disease. Circulation. 75:395-400.
127. Rocco MB, Nabel EG, Selwyn AP. 1987. Circadian rhythms and coronary artery disease. Am J Cardiol. 59:13C-17C.
128. Rostagno C, Taddei T, Paladini B, et al. 1993. The onset of symptomatic atrial fibrillation and paroxysmal supraventricular tachycardia is characterized by different circadian rhythms. Am J Cardiol. 71:453-455.
129. Sakata K, Hoshino T, Yoshida H, et al. 1992. Circadian fluctuations of tissue plasmino-gen activator antigen and plasminogen activator inhibitor-1 antigens in vasospastic angina. Am Heart J. 124:854-860.
130. Shimada K, Kawamoto A, Matsubayashi K, et al. 1990. Silent cerebrovascular disease in the elderly. Correlation with ambulatory pressure. Hypertension. 16:692-699.
131. Shimada K, Kawamoto A, Matsubayashi K, et al. 1992. Diurnal blood pressure variations and silent cerebrovascular damage in elderly patients with hypertension. J Hypertens. 10:875-878.
132. Siegel D, Black DM, Seeley DG, et al. 1992. Circadian variation in ventricular arrhythmias in hypertensive men. Am J Cardiol. 69:344-347.
133. Sloan MA, Price TR, Foulkes MA, et al. 1992. Circadian rhythmicity of stroke onset. Intracerebral and subarachnoid hemorrhage. Stroke. 23:1420-1426.
134. Somers VK, Dyken ME, Mark AL, et al. 1993. Sympathetic-nerve activity during sleep in normal subjects. N Engl J Med. 328:303-307.
135. Statius van Eps RG, van den Meiracker AH, Boomsma F, et al. 1994. Diurnal variation of blood pressure in patients with catecholamine-producing tumors. Am J Hypertens 7:492-497.
136. Struck LK, Rodnitzky RL. 1989. Periodicity of ischemic stroke. Stroke. 20:1590.
137. Suzuki Y, Kuwajima I, Mitani K, et al. 1993. The relation of morning rise in blood pressure to pressure response to exercise and mental stress. Jpn J Geriatr. 30:841-848.
138. Thompson DR, Blandford RL, Sutton TW, et al. 1985. Time of onset of chest pain in acute myocardial infarction. Int J Cardiol. 7:139-148.
139. Tofler GH, Brezinski D, Schafer AI, et al. 1987. Concurrent morning increase in platelet aggregability and the risk of myocardial infarction and sudden cardiac death. N Engl J Med. 316:1514-1518.
140. Toni D, Argentino C, Gentile M, et al. 1991. Circadian variation in the onset of acute cerebral ischemia: ethiopathogenetic correlates in 80 patients given angiography. Chronobiol Int. 8:321-326.
141. Touitou Y, Touitou C, Bogdan A, et al. 1986. Differences between young and elderly subjects in seasonal and circadian variations of total plasma proteins and blood volume as reflected by hemoglobin, hematocrit, and erythrocyte counts. Clin Chem. 32:801-804.
142. Tsementzis SA, Gill JS, Hitchcock ER, et al. 1985. Diurnal variation of and activity during the onset of stroke. Neurosurgery. 17:901-904.
143. Turton MB, Deegan T. 1974. Circadian variations of plasma catecholamine, cortisol and immunoreactive insulin concentrations in supine subjects. Clin Chim Acta. 55:389-397.
144. Twidale N, Taylor S, Heddle WF, et al. 1989. Morning increase in the time of onset of sustained ventricular tachycardia. Am J Cardiol. 64:1204-1206.
145. Valkama JO, Huikuri HV, Linnaluoto MK, et al. 1992. Circadian variation of ventricular tachycardia in patients with coronary arterial disease. Int J Cardiol. 34:173-178.
146. van de Borne P, Gelin M, Van de Stadt J, et al. 1993. Circadian rhythms of blood pressure after liver transplantation. Hypertension. 21:398-405.
147. Vaziri ND, Kennedy SC, Kennedy D, et al. 1992. Coagulation, fibrinolytic, and inhibitory proteins in acute myocardial infarction and angina pectoris. Am J Med. 93:651-657.
148. Veglio F, Pinna G, Melchio R, et al. 1993. Twenty-four-hour power spectral analysis by maximum entropy method of blood pressure in primary hyperaldosteronism. Blood Press. 2:189-196.
149. Verdecchia P, Porcellati C, Schillaci G, et al. 1994. Ambulatory blood pressure. An independent predictor of prognosis in essential hypertension. Hypertension. 24: 793-801.
150. Verdecchia P, Schillaci G, Gatteschi C, et al. 1993. Blunted nocturnal fall in blood pressure in hypertensive women with future cardiovascular morbid events. Circulation. 88:986-992.
151. Verdecchia P, Schillaci G, Guerrieri M, et al. 1990. Circadian blood pressure changes and left ventricular hypertrophy in essential hypertension. Circulation. 81:528-536.
152. Wannamethee G, Perry IJ, Shaper AG. 1994. Haematocrit, hypertension and risk of stroke. J Intern Med. 235:163-168.
153. Waters DD, Miller DD, Bouchard A, et al. 1984. Circadian variation in variant angina. Am J Cardiol. 54:61-64.
154. Weitzman ED, Fukushima D, Nogeire C, et al. 1971. Twenty-four hour pattern of the episodic secretion of cortisol in normal subjects. J Clin Endocrinol Metab. 33: 14-22.
155. White WB, Malchoff C. 1992. Diurnal blood pressure variability in mineralocorticoid excess syndrome. Am J Hypertens. 5:414-418.
156. Willich SN, Levy D, Rocco MB, et al. 1987. Circadian variation in the incidence of sudden cardiac death in the Framingham Heart Study population. Am J Cardiol. 60:801-806.
157. Willich SN, Linderer T, Wegscheider K, et al. 1989. Increased morning incidence of myocardial infarction in the ISAM Study: absence with prior beta-adrenergic blockade. ISAM Study Group. Circulation. 80:853-858.
158. Willich SN, Sintonen SP, Bathia SS. 1988. Morning increase in platelet aggregability in patients with coronary artery disease [abstract]. J Am Coll Cardiol. 11:204.
159. Winther K, Hillegass W, Tofler GH, et al. 1992. Effects on platelet aggregation and fibrinolytic activity during upright posture and exercise in healthy men. Am J Cardiol. 70:1051-1055.
160. Yasue H, Omote S, Takizawa A, et al. 1979. Circadian variation of exercise capacity in patients with Prinzmetal's variant angina: role of exercise-induced coronary arterial spasm. Circulation. 59:938-948.