A genetically modified recombinant tumor necrosis factor-α conjugated to the distal terminals of liposomal surface grafted polyethyleneglycol chains

International Journal of Pharmaceutics

Volumn 184, Issue 1, 1999, Pages 45-51

  Savva, Michalakis ^a   Duda, Ernò ^b   Huang, Leaf ^a  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

Author keywords

Cytotoxicity; Liposome; Polyethyleneglycol; TNF

Indexed keywords

CARBOXYL GROUP; CHOLESTEROL; INDIUM 111; IODINE 125; LIPOSOME; MACROGOL; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLETHANOLAMINE; RECOMBINANT TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL STRAIN L 929; CONTROLLED STUDY; CYTOTOXICITY; DRUG BLOOD LEVEL; DRUG CONJUGATION; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG HALF LIFE; FEMALE; GENETICS; INTRAVENOUS DRUG ADMINISTRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; RETICULOENDOTHELIAL SYSTEM;

ANIMALS; CHOLESTEROL; FEMALE; LIPOSOMES; MICE; MICE, INBRED C3H; PHARMACEUTIC AIDS; PHOSPHATIDYLCHOLINES; PHOSPHATIDYLETHANOLAMINES; POLYETHYLENE GLYCOLS; RECOMBINANT PROTEINS; TISSUE DISTRIBUTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0033032889     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(99)00092-7     Document Type: Article

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