Structural parameters involved in the permeation of propranolol HCl by iontophoresis and enhancers

Journal of Controlled Release

Volumn 58, Issue 2, 1999, Pages 163-175

  Chesnoy, Sophie ^a   Durand, Dominique ^b   Doucet, Jean ^b   Couarraze, Guy ^a  

^a UNIV PARIS SUD   (France)

^b UNIVERSITÉ PARIS SACLAY   (France)

Author keywords

DSC; Enhancers; Infrared spectroscopy; Iontophoresis; X ray diffraction

Indexed keywords

CETRIMIDE; DODECYL SULFATE SODIUM; PENETRATION ENHANCING AGENT; PROPRANOLOL;

ARTICLE; DIFFERENTIAL SCANNING CALORIMETRY; DIFFUSION; DRUG TRANSPORT; FEMALE; HUMAN; HUMAN TISSUE; INFRARED SPECTROSCOPY; IONTOPHORESIS; PRIORITY JOURNAL; SKIN PERMEABILITY; STRATUM CORNEUM; X RAY DIFFRACTION;

ADRENERGIC BETA-ANTAGONISTS; ADULT; CALORIMETRY, DIFFERENTIAL SCANNING; EXCIPIENTS; FEMALE; HUMANS; IONTOPHORESIS; PROPRANOLOL; SKIN ABSORPTION; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; X-RAY DIFFRACTION;

EID: 0033032658     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(98)00155-2     Document Type: Article

References (17)

1. Lashmar U.T., Manger J. Investigation into the potential for iontophoresis facilitated transdermal delivery of acyclovir. Int. J. Pharm. 111:1994;73-82.
2. Wang Y., Allen L.C.V., Li L.C., Tu Y.-H. Iontophoresis of hydrocortisone across hairless mouse skin: investigation of skin alteration. J. Pharm. Sci. 82:1993;1140-1144.
3. Kalia Y.N., Guy R.H. The electrical characteristics of human skin in vivo. Pharm. Res. 12:1995;1605-1613.
4. Thysman S., Van Neste D., Préat V. Noninvasive investigation of human skin after in vivo iontophoresis. Skin Pharmacol. 8:1995;229-236.
5. Jadoul A., Doucet J., Durand D., Préat V. Modifications induced on stratum corneum after in vitro iontophoresis: ATR-FTIR and X-ray scattering studies. J. Control. Release. 42:1996;165-173.
6. Chesnoy S., Doucet J., Durand D., Couarraze G. Effect of iontophoresis in combination with ionic enhancers on the lipid structure of the stratum corneum: an X-ray diffraction study. Pharm. Res. 13:1996;1581-1584.
7. Bouwstra J.A., Gooris G.S., Van der Spek J.A., Bras W. Structural investigations of human stratum corneum by small-angle X-ray scattering. J. Invest. Dermatol. 97:1991;1005-1012.
8. G. Porod, Small-angle X-ray Scattering, Glatter and Kratky, London, 1982.
9. Harrison J.E., Groundwater P.W., Brain K.R., Hadgraft J. Azone induced fluidity in human stratum corneum. A Fourier transform infrared spectroscopy investigation using the perdeuterated analogue. J. Control. Release. 41:1996;283-290.
10. Bouwstra J.A., Gooris G.S., Salomons-de Vries M.A., Van der Spek J.A., Bras W. Structure of human stratum corneum as a function of temperature and hydration: a wide-angle X-ray diffraction study. Int. J. Pharm. 84:1992;205-216.
11. Golden G.M., Guzek D.B., Harris R.R., McKie J.E., Potts R.O. Lipid thermotropic transitions in human stratum corneum. J. Invest. Dermatol. 86:1986;255-259.
12. Barry B.W. Mode of action of penetration enhancers in human skin. J. Control. Release. 6:1987;85-97.
13. Cornwell P.A., Barry B.W., Bouwstra J.A., Gooris G. Modes of action of terpene penetration enhancers in human skin; differential scanning calorimetry, small-angle X-ray diffraction and enhancer uptake studies. Int. J. Pharm. 127:1996;9-26.
14. Nolan L.M.A., Corish J. Electrical properties of human stratum corneum and transdermal drug transport. J. Chem. Soc. Faraday Trans. 89:1993;2839-2845.
15. Kalia Y.N., Guy R.H. Interaction between penetration enhancers and iontophoresis: effect on human skin impedance in vivo. J. Control. Release. 44:1997;33-42.
16. Pikal M.J. Transport mechanisms in iontophoresis. I. A theoretical model for the effect of electroosmotic flow on flux enhancement in transdermal iontophoresis. Pharm. Res. 7:1990;118-126.
17. Gay C.L., Guy R.H., Golden G.M., Mak V.H.W., Francoeur M.L. Characterization of low-temperature (i.e. <65°C) lipid transitions in human stratum corneum. J. Invest. Dermatol. 86:1986;255-259.