Pharmacokinetics of the antihyperglycemic agent metformin in cats

American Journal of Veterinary Research

Volumn 60, Issue 6, 1999, Pages 738-742

  Michels, Gina M ^a   Boudinot, E Douglas ^a   Ferguson, Duncan C ^a   Hoenig, Margarethe ^a  

^a UNIVERSITY OF GEORGIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

METFORMIN;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CAT; COMPARTMENT MODEL; COMPUTER SIMULATION; CONTROLLED STUDY; DIABETES MELLITUS; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG STRUCTURE; DRUG URINE LEVEL; FEMALE; INTRAVENOUS DRUG ADMINISTRATION; NONHUMAN; ORAL DRUG ADMINISTRATION;

ANIMALIA; FELIS CATUS;

EID: 0033032623     PISSN: 00029645     EISSN: None     Source Type: Journal    
DOI: 10.2460/ajvr.1999.60.06.738     Document Type: Article

References (14)

1. Dunn CJ, Peters DH. Metformin: a review of its pharmacological properties and therapeutic use in non-insulin-dependent diabetes mellitus. Drugs 1995;49:721-749.
2. Caille G, Lacasse Y, Raymond M. Bioavailability of metformin in tablet form using a new high pressure liquid chromatography assay method. Biopharm Drug Dispos 1993;14:257-263.
3. Pentikäinen PJ, Neuvonen PJ, Penttilä A. Pharmacokinetics of metformin after intravenous and oral administration to man. Eur J Clin Pharmacol 1979;16:195-202.
4. Sirtori CR, Franceschini MS, Galli-Kienle M, et al. Disposition of metformin (N,N-dimethylbiguanide) in man. Clin Pharmacol Ther 1978;24:683-693.
5. Assan R, Heuclin CH, Ganeval D, et al. Metformin-induced lactic acidosis in the presence of acute renal failure. Diabetologica 1977; 13:211-217.
6. Vesterqvist O, Nabbie F, Swanson B. Determination of metformin in plasma by high-performance liquid chromatography after ultrafiltration. J Chromatogr 1998;716:299-304
7. Boxenbaum HG, Riegelman S, Eelashoff RM. Statistical estimates in pharmacokinetics. J Pharamcokinet Biopharm 1974;6:123-148.
8. Gibaldi M, Perrier D. Multicompartmental models. In: Pharmacokinetics. 2nd ed. New York: Marcel Dekker Ine, 1982; 44-144.
9. Metzler M, Elfring G, McEwen A. A package of computer programs for pharmacokinetic modeling. Biometrics 1974;130:562-563.
10. Lam FC, Hung CT, Perrier DG. Estimation of variance for harmonic mean half-lives. J Pharm Sci 1985;74:229-231.
11. Rocci ML, Jusko WJ. LAGRAN program for area and moments in pharmacokinetic analysis. Comput Prog Biomed 1983;16: 203-216.
12. Chew DJ, de Morais HS. Parenteral fluid therapy. In: Sherding RG, ed. The cat: diseases and clinical management. 2nd ed. New York: Churchill Livingstone Inc, 1994;39-89.
13. Tucker GT, Casey C, Phillips PJ, et al. Metformin kinetics in healthy subjects and in patients with diabetes mellitus. Br J Clin Pharmacol 1981;12:235-246.
14. Finco DR, Tabaru H, Brown SA, et al. Endogenous creatinine clearance measurement of glomerular filtration rate in dogs. Am J Vet Res 1993;54:1575-1578.