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Volumn 18, Issue 1, 1999, Pages 16-25

Computer aided predicting the biological activity spectra and experimental testing of new thiazole derivatives

Author keywords

Antioxidants; Benzothiazoles; Biological activity spectra prediction; Computer system pass; Local anaestetics; NSAID; Structure activity relationships; Thiazoles

Indexed keywords

ANTIOXIDANTS; BIOACTIVITY; COMPUTER AIDED ANALYSIS; INDIUM COMPOUNDS;

EID: 0033032569     PISSN: 09318771     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-3838(199901)18:1<16::AID-QSAR16>3.0.CO;2-O     Document Type: Article
Times cited : (21)

References (41)
  • 3
    • 0345372860 scopus 로고
    • Synthesis of new local anaesthetics II
    • Bhargava, P.N. and Singh, P.R., Synthesis of new local anaesthetics II. J. Indian Chem. Soc. 37, 241-243 (1960).
    • (1960) J. Indian Chem. Soc. , vol.37 , pp. 241-243
    • Bhargava, P.N.1    Singh, P.R.2
  • 5
    • 0242469348 scopus 로고
    • Synthesis of new local anaesthetics III
    • Bhargava, P.N. and Jose, K.A., Synthesis of new local anaesthetics III. J. Indian Chem. Soc. 37, 314-316 (1960).
    • (1960) J. Indian Chem. Soc. , vol.37 , pp. 314-316
    • Bhargava, P.N.1    Jose, K.A.2
  • 6
    • 0014752307 scopus 로고
    • Synthesis of some local anaesthetics
    • Srivastava, P.N. and Srivastava, P.K., Synthesis of some local anaesthetics. J. Med. Chem. 13, 304-305 (1970).
    • (1970) J. Med. Chem. , vol.13 , pp. 304-305
    • Srivastava, P.N.1    Srivastava, P.K.2
  • 7
    • 33947435279 scopus 로고
    • The reaction of ketones with halogens and thiourea
    • King, L.C. and Dodson, P.M., The reaction of ketones with Halogens and Thiourea. J. Amer. Chem. Soc. 67, 2242-2243 (1945).
    • (1945) J. Amer. Chem. Soc. , vol.67 , pp. 2242-2243
    • King, L.C.1    Dodson, P.M.2
  • 8
    • 1842440351 scopus 로고
    • The reaction of acetophenone with thiourea and oxidizing agents
    • King, L.C. and Dodson, P.M., The reaction of acetophenone with Thiourea and Oxidizing agents. J.Amer. Chem. Soc. 68, 871 (1945).
    • (1945) J.Amer. Chem. Soc. , vol.68 , pp. 871
    • King, L.C.1    Dodson, P.M.2
  • 9
    • 0026442636 scopus 로고
    • Synthesis of 2-(aminoacetylamino)thiazole derivatives and comparison of their local anaesthetic activity by method of action potential
    • Geronikaki, A. and Theophilidis, G., Synthesis of 2-(aminoacetylamino)thiazole derivatives and comparison of their local anaesthetic activity by method of action potential. Eur. J. Med. Chem. 27, 709-716 (1992).
    • (1992) Eur. J. Med. Chem. , vol.27 , pp. 709-716
    • Geronikaki, A.1    Theophilidis, G.2
  • 10
    • 0017373271 scopus 로고
    • Synthesis and potential local anaesthetic activity of some 2-substituted benzothiazoles
    • Srivastava, P.K., Sharma, R.D., Upadhyaya, J.S., Synthesis and potential local anaesthetic activity of some 2-substituted benzothiazoles. Indian J. Pharmacy. 39, 56-58 (1977).
    • (1977) Indian J. Pharmacy , vol.39 , pp. 56-58
    • Srivastava, P.K.1    Sharma, R.D.2    Upadhyaya, J.S.3
  • 11
    • 0017591501 scopus 로고
    • Search for new local anaesthetic agents. III Synthesis of 2-alkyl-arylamino-acetylamino-4-phenylthiazoles
    • Srivastava, P.K., Sharma, R.D., Rai, S.K., Search for new local anaesthetic agents. III Synthesis of 2-alkyl-arylamino-acetylamino-4-phenylthiazoles. Acta Chim. 94, 229-232 (1977).
    • (1977) Acta Chim. , vol.94 , pp. 229-232
    • Srivastava, P.K.1    Sharma, R.D.2    Rai, S.K.3
  • 12
    • 0344248253 scopus 로고
    • Synthesis and potential local anaesthetic activity of some derivatives of substituted 2-aminobenzothiazoles III
    • Srivastava, P.K., Rai, S.K., Yadav, G.C., Synthesis and potential local anaesthetic activity of some derivatives of substituted 2-aminobenzothiazoles III. Curr. Sci. 48, 711 (1979).
    • (1979) Curr. Sci. , vol.48 , pp. 711
    • Srivastava, P.K.1    Rai, S.K.2    Yadav, G.C.3
  • 13
    • 0022976902 scopus 로고
    • Local anaesthetics IV. Synthesis and activity of 2-(N-substituted or N,N-disubstituted aminoacetamido)-4 or 4,5-substituted thiazoles
    • Lakhan, R. and Rai, B.J., Local anaesthetics IV. Synthesis and activity of 2-(N-substituted or N,N-disubstituted aminoacetamido)-4 or 4,5-substituted thiazoles. Il Farmaco. 41, 788-783 (1986).
    • (1986) Il Farmaco. , vol.41 , pp. 788-1783
    • Lakhan, R.1    Rai, B.J.2
  • 14
    • 0025132156 scopus 로고
    • Synthesis and local anaesthetic activity of alkyl aminoacyl derivatives of 3-amino-1,2-benzoisothiazoles
    • Vicini, P., Amoretti, L., Chiavarini, M., Impicciatore, M., Synthesis and local anaesthetic activity of alkyl aminoacyl derivatives of 3-amino-1,2-benzoisothiazoles. Il Farmaco. 45, 933-944 (1990).
    • (1990) Il Farmaco. , vol.45 , pp. 933-944
    • Vicini, P.1    Amoretti, L.2    Chiavarini, M.3    Impicciatore, M.4
  • 15
    • 0020973794 scopus 로고
    • 4,5-Bis (4-methoxyphenyl)-2-arylthio-azole mit antiphlogischer wirkung
    • Klose, N., Niedbolla, K., Schwartz, K., Bottcher, I., 4,5-Bis (4-methoxyphenyl)-2-arylthio-azole mit antiphlogischer wirkung. Arch. Pharm. 316, 941-951 (1983).
    • (1983) Arch. Pharm. , vol.316 , pp. 941-951
    • Klose, N.1    Niedbolla, K.2    Schwartz, K.3    Bottcher, I.4
  • 16
    • 0020612202 scopus 로고
    • 1-(4-Substituted-thiazol-2-yl) hydantoins as antiinflammatory and CNS-active agents
    • Satsangi, R.K., Zaidi, S.M., Misra, V.S., 1-(4-Substituted-thiazol-2-yl) hydantoins as antiinflammatory and CNS-active agents. Pharmazie. 38, 341-342 (1983).
    • (1983) Pharmazie , vol.38 , pp. 341-342
    • Satsangi, R.K.1    Zaidi, S.M.2    Misra, V.S.3
  • 18
    • 85192685304 scopus 로고
    • Sc.D. in Pharmacology Thesis (Rus). Staraya Kupavna (Moscow Region): Natl. Res. Center for Biologically Active Compounds, 348 pp.
    • Poroikov, V.V., Computer aided prediction in new drug research and development. Sc.D. in Pharmacology Thesis (Rus). Staraya Kupavna (Moscow Region): Natl. Res. Center for Biologically Active Compounds, 348 pp.(1995) .
    • (1995) Computer Aided Prediction in New Drug Research and Development
    • Poroikov, V.V.1
  • 19
    • 0002344033 scopus 로고
    • Computer-aided prediction of biological activity spectra of chemical substances on the basis of their structural formulae: Computerized system PASS
    • Filimonov, D.A., Poroikov, V.V., Karaicheva, E.I. et. al., Computer-aided prediction of biological activity spectra of chemical substances on the basis of their structural formulae: computerized system PASS. Experimental and Clinical Pharmacology (Rus). 58, 56-62 (1995).
    • (1995) Experimental and Clinical Pharmacology (Rus) , vol.58 , pp. 56-62
    • Filimonov, D.A.1    Poroikov, V.V.2    Karaicheva, E.I.3
  • 20
    • 0002690227 scopus 로고    scopus 로고
    • PASS: Computerized prediction of biological activity spectra for chemical substances
    • BIOS Scientific Publishers, Oxford
    • Filimonov, D.A. and Poroikov, V.V., PASS: Computerized prediction of biological activity spectra for chemical substances. In: Bioactive Compound Design: Possibilities for Industrial Use, BIOS Scientific Publishers, Oxford, 47-56 (1996).
    • (1996) Bioactive Compound Design: Possibilities for Industrial Use , pp. 47-56
    • Filimonov, D.A.1    Poroikov, V.V.2
  • 21
    • 0003556116 scopus 로고
    • Comparison of the results of prediction of the spectra of biological activity of chemical compounds by experts and the PASS system
    • Allerton Press, Inc.
    • Poroikov, V.V, Filimonov, D.A., Boudunova, A.P., Comparison of the results of prediction of the spectra of biological activity of chemical compounds by experts and the PASS system. Automatic Documentation and Mathematical Linguistics. Allerton Press, Inc. 27, 40-43 (1993).
    • (1993) Automatic Documentation and Mathematical Linguistics , vol.27 , pp. 40-43
    • Poroikov, V.V.1    Filimonov, D.A.2    Boudunova, A.P.3
  • 22
    • 85192672389 scopus 로고    scopus 로고
    • Russian computer program to cut screening costs?
    • Charlish, P., Russian computer program to cut screening costs? Pharma Rrojects Magazine. 1, No 11, 2-3 (1996).
    • (1996) Pharma Rrojects Magazine , vol.1 , Issue.11 , pp. 2-3
    • Charlish, P.1
  • 23
    • 85192671807 scopus 로고    scopus 로고
    • Computer assisted prediction of biological activity spectra: Estimating the effectivity of use in high throughput screening
    • Maastricht (The Netherlands). P-3.05
    • Poroikov, V.V, Filimonov, D.A., Boudouna, A.P., Computer assisted prediction of biological activity spectra: estimating the effectivity of use in high throughput screening. In: Abstr.: XIV International Symposium on Medicinal Chemistry, Maastricht (The Netherlands). P-3.05 (1996).
    • (1996) Abstr.: XIV International Symposium on Medicinal Chemistry
    • Poroikov, V.V.1    Filimonov, D.A.2    Boudouna, A.P.3
  • 28
    • 0019494733 scopus 로고
    • Synthesis of aminoalkyl-substituted imidazo[1,2]- and imidazo[1,5]-benzodiazepines
    • Gall, M. and Kamdaw, B.V., Synthesis of aminoalkyl-substituted imidazo[1,2]- and imidazo[1,5]-benzodiazepines. J. Org. Chem. 46, 1575. (1981).
    • (1981) J. Org. Chem. , vol.46 , pp. 1575
    • Gall, M.1    Kamdaw, B.V.2
  • 29
    • 0024661020 scopus 로고
    • Synthesis of some thiazole derivatives with prospective local anaesthetic activity
    • Geronikaki, A., Sotiropoulou, E., Kourounakis, P., Synthesis of some thiazole derivatives with prospective local anaesthetic activity. Pharmazie. 44, 349 (1989).
    • (1989) Pharmazie , vol.44 , pp. 349
    • Geronikaki, A.1    Sotiropoulou, E.2    Kourounakis, P.3
  • 30
    • 0026606287 scopus 로고
    • Synthesis and mass spectra of some thiazole aminoketones with prospective local anaesthetic activity
    • Geronikaki, A., Sotiropoulou, E., Kourounakis, P.N., Synthesis and mass spectra of some thiazole aminoketones with prospective local anaesthetic activity. Pharmazie. 47, 298-300 (1992).
    • (1992) Pharmazie , vol.47 , pp. 298-300
    • Geronikaki, A.1    Sotiropoulou, E.2    Kourounakis, P.N.3
  • 31
    • 0029003558 scopus 로고
    • Synthesis and antiinflammatory activity of some new thiazole derivatives
    • Mgonzo, R., Geronikaki, A., Kourounakis, P., Synthesis and antiinflammatory activity of some new thiazole derivatives. Pharmazie. 50, 505-506 (1995).
    • (1995) Pharmazie , vol.50 , pp. 505-506
    • Mgonzo, R.1    Geronikaki, A.2    Kourounakis, P.3
  • 33
    • 0025569541 scopus 로고
    • Synthesis and studies of some thiazole Schiff bases
    • Geronikaki, A., Synthesis and studies of some thiazole Schiff bases. Farmatsija. 40, 17-22 (1990).
    • (1990) Farmatsija , vol.40 , pp. 17-22
    • Geronikaki, A.1
  • 35
    • 0030451835 scopus 로고    scopus 로고
    • In vitro studies of some 2,4-disubstituted thiazolyl-aminoketones with antiinfiammatory activity. Correlation with lipophilicity and structural characteristics
    • II
    • Geronikaki, A. and Hadjipavlou-Litina, D., In vitro studies of some 2,4-disubstituted thiazolyl-aminoketones with antiinfiammatory activity. Correlation with lipophilicity and structural characteristics. Arz. Forsh./Drug Res. 46 (II), 1134-1137 (1996).
    • (1996) Arz. Forsh./Drug Res. , vol.46 , pp. 1134-1137
    • Geronikaki, A.1    Hadjipavlou-Litina, D.2
  • 36
    • 0345317191 scopus 로고    scopus 로고
    • Synthesis of new thiazole derivatives and comparative study of their local anaesthetic activity using the evoked action potential in the sciatic nerve
    • Mgonzo, R., Geronikaki, A., Theophilidis, G., Synthesis of new thiazole derivatives and comparative study of their local anaesthetic activity using the evoked action potential in the sciatic nerve. Res. Commun. in Pharmacol. and Toxicol. 1 Nos. 2 & 3, 137-148 (1996).
    • (1996) Res. Commun. in Pharmacol. and Toxicol. , vol.1 , Issue.2-3 , pp. 137-148
    • Mgonzo, R.1    Geronikaki, A.2    Theophilidis, G.3
  • 37
    • 0027744226 scopus 로고
    • Lipophilicity and biological studies of some 2-(aminoacetylamino)thiazole derivatives with antiinflammatory activity
    • Geronikaki, A. and Hadjipavlou-Litina, D., Lipophilicity and biological studies of some 2-(aminoacetylamino)thiazole derivatives with antiinflammatory activity. Pharmazie. 48, 948-949 (1993).
    • (1993) Pharmazie , vol.48 , pp. 948-949
    • Geronikaki, A.1    Hadjipavlou-Litina, D.2
  • 39
    • 0030811753 scopus 로고    scopus 로고
    • Effect of 2,4-disubstituted thiazol-5-yl aminoketones on carrageenin induced inflammation. Biological evaluation and a structure-activity approach
    • Hadjipavlou-Litina, D.J. and Geronikaki, A.A., Effect of 2,4-disubstituted thiazol-5-yl aminoketones on carrageenin induced inflammation. Biological evaluation and a structure-activity approach. Res. Commun.in Molecular Pathol and Pharmacol. 96, 307-318 (1997).
    • (1997) Res. Commun.in Molecular Pathol and Pharmacol. , vol.96 , pp. 307-318
    • Hadjipavlou-Litina, D.J.1    Geronikaki, A.A.2


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