Characterisation of a chloramphenicol acetyltransferase determinant found in the chromosome of Pseudomonas aeruginosa

FEMS Microbiology Letters

Volumn 175, Issue 1, 1999, Pages 27-35

  White, Peter A ^a   Stokes, H W ^a   Bunny, Kim L ^a,c   Hall, Ruth M ^b  

^a MACQUARIE UNIVERSITY   (Australia)

^b CSIRO   (Australia)

^c UNIVERSITY OF UTAH   (United States)

Author keywords

Acetyltransferase; catB7; Chloramphenicol resistance; Pseudomonas aeruginosa

Indexed keywords

CHLORAMPHENICOL ACETYLTRANSFERASE;

ANTIBIOTIC RESISTANCE; ARTICLE; CHROMOSOME MAP; GENETIC ANALYSIS; MOLECULAR CLONING; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PRIORITY JOURNAL; PROTEIN EXPRESSION; PSEUDOMONAS AERUGINOSA;

AMINO ACID SEQUENCE; ANTI-BACTERIAL AGENTS; BASE SEQUENCE; CHLORAMPHENICOL; CHLORAMPHENICOL O-ACETYLTRANSFERASE; CHLORAMPHENICOL RESISTANCE; CHROMOSOMES, BACTERIAL; GENES, BACTERIAL; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA; OPEN READING FRAMES; PSEUDOMONAS; PSEUDOMONAS AERUGINOSA; SEQUENCE ANALYSIS, DNA;

ESCHERICHIA COLI; FELIS CATUS; PSEUDOMONAS; PSEUDOMONAS AERUGINOSA;

EID: 0033031699     PISSN: 03781097     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1097(99)00171-8     Document Type: Article

References (31)

1. Bannam, T.L. and Rood, J.I. (1991) Relationship between the Clostridium perfringens catQ gene product and chloramphenicol acetyltransferases from other bacteria. Antimicrob. Agents Chemother. 35, 471-476.
2. Huggins, A.S., Bannam T.L. and Rood, J.I. (1992) Comparative sequence analysis of the catB gene from Clostridium butyricum. Antimicrob. Agents Chemother. 36, 2548-2551.
3. Parent, R. and Roy, P.H. (1992) The chloramphenicol acetyltransferase gene of Tn2424: a new breed of cat. J. Bacteriol. 174, 2891-2897.
4. Tennigkeit, J. and Matzura, H. (1991) Nucleotide sequence analysis of a chloramphenicol-resistance determinant from Agrobacterium tumefaciens and identification of its gene product. Gene 98, 113-116.
5. Bunny, K.L., Hall, R.M. and Stokes, H.W. (1995) New mobile gene cassettes containing an aminoglycoside resistance gene, aacA7, and a chloramphenicol resistance gene, catB3, in an integron in pBWH301. Antimicrob. Agents Chemother. 39, 686-693.
6. Hall, R.M., Brookes, D.E. and Stokes, H.W. (1991) Site-specific insertion of genes into integrons: role of the 59-base element and determination of the recombination cross-over point. Mol. Microbiol. 5, 1941-1959.
7. Recchia, G.D. and Hall, R.M. (1995) Gene cassettes: a new class of mobile element. Microbiology 141, 3015-3027.
8. Stokes, H.W. and Hall, R.M. (1989) A novel family of potentially mobile DNA elements encoding site-specific gene-integration functions: integrons. Mol. Microbiol. 3, 1669-1683.
9. Hall, R.M. and Collis, C.M. (1995) Mobile gene cassettes and integrons: capture and spread of genes by site-specific recombination. Mol. Microbiol. 15, 593-600.
10. Haas, D. and Holloway, B.W. (1976) R factor variants with enhanced sex factor activity in Pseudomonas aeruginosa. Mol. Gen. Genet. 144, 243-251.
11. Davison, A.D. and Veal, D.A. (1993) Storage of a mixed microbial consortium capable of growth on biphenyl. Lett. Appl. Microbiol. 17, 101-103.
12. Hanahan, D. (1983) Studies on transformation of Escherichia coli with plasmids. J. Mol. Biol. 166, 570-580.
13. Alton, N.B. and Vapnek, D. (1979) Nucleotide sequence of the chloramphenicol resistance transposon Tn9. Nature 282, 864-869.
14. Gillings, M. and Fahy, P. (1993) Genetic diversity of Pseudomonas solanacearum biovars 2 and N2 assessed using restriction endonuclease analysis of total genomic DNA. Plant Pathol. 42, 744-753.
15. Hruby, D.E. and Wilson, E.M. (1992) Use of fluorescent chloramphenicol derivative as a substrate for chloramphenicol acetyltransferase assays. Methods Enzymol. 216, 369-376.
16. Young, S.L., Barbera, L., Kaynard, A.H., Haugland, R.P., Kang, H.C., Brinkley, M. and Melner, M.H. (1991) A non-radioactive assay for transfected chloramphenicol acetyltransferase activity using fluorescent substrates. Anal. Biochem. 197, 401-407.
17. Kleanthous, C. and Shaw, W. V. (1984) Analysis of the mechanism of chloramphenicol acetyltransferase by steady-state kinetics. Biochem. J. 223, 211-220.
18. Lineweaver, H. and Burk, D. (1934) The determination of enzyme dissociation constants. J. Am. Chem. Soc. 56, 658-666.
19. Lerner, C.G. and Inouye, M. (1990) Low copy number plasmids for regulated low-level expression of cloned genes in Escherichia coli with blue/white insert screening capability. Nucleic Acids Res. 18, 4631.
20. Sun, L., Sreedharan, S., Plummer, K. and Fisher, L.M. (1996) NorA plasmid resistance to fluoroquinolones: Role of copy number and NorA frame shift mutations. Antimicrob. Agents Chemother. 40, 1665-1669.
21. Chang, A.C.Y. and Cohen, S.N. (1978) Construction and characterization of amplifiable multicopy DNA cloning vehicles derived from P15A cryptic miniplasmid. J. Bacteriol. 134, 1141-1156.
22. Wick, M.J., Frank, D.W., Storey, D.G. and Iglewski, B.H. (1990) Identification of regB, a gene required for optimal exotoxin A yields in Pseudomonas aeruginosa. Mol. Microbiol. 4, 489-497.
23. Shaw, W.V. (1983) Chloramphenicol acetyltransferase: enzymology and molecular biology. Crit. Rev. Biochem. 14, 1-46.
24. Zaidenzaig, Y., Fitton, J.E., Packman L.E. and Shaw, W.V. (1979) Characterization and comparison of chloramphenicol acetyltransferase variants. Eur. J. Biochem. 100, 609-618.
25. Murray, I.A. and Shaw, W.V. (1997) O-acetylation for chloramphenicol and other natural products. Antimicrob. Agents Chemother. 41, 1-6.
26. Allignet, J. and El Solh, N. (1995) Diversity among the Grampositive acetyltransferases inactivating streptogramin A and structurally related compounds and characterization of a new staphylococcal determinant, vatB. Antimicrob. Agents Chemother. 39, 2027-2036.
27. Rende-Fournier, R., Leclercq, R., Galimand, M., Duval, J. and Courvalin, P. (1993) Identification of the satA gene encoding a streptogramin A acetyltransferase in Enterococcus faecium BM4145. Antimicrob. Agents Chemother. 37, 2119-2125.
28. Allignet, J., Loncle, V., Simenel, C., Delepierre, M. and El Solh, N. (1993) Sequence of a staphylococcal gene, vat, encoding an acetyltransferase inactivating the A-type compounds of virginiamycin-like antibiotics. Gene 130, 91-98.
29. Monod, M., Mohan, S. and Dubnau, D. (1987) Cloning and analysis of ermG, a new macrolide-lincosamide-streptogramin B resistance element from Bacillus sphaericus. J. Bacteriol. 169, 340-350.
30. Vuorio, R., Hirvas, L. and Vaara, M. (1991) The Ssc protein of enteric bacteria has significant homology to the acyltransferase Lpxa of lipid A biosynthesis, and to three acetyltransferases. FEBS Lett. 292, 90-94.
31. Recchia, G.D. and Hall, R.M. (1997) Origins of gene cassettes found in integrons. Trends Microbiol. 5, 389-394.