Virilizing ovarian dermoid cyst with peripheral steroid cells: A case study with immunohistochemical study of steroidogenesis

International Journal of Gynecological Pathology

Volumn 18, Issue 2, 1999, Pages 174-177

  Boman, Françoise ^a,b   Vantyghem, Marie Christine ^a   Querleu, Denis ^a,b   Sasano, Hironobu ^c  

^a LILLE UNIVERSITY HOSPITAL   (France)

^b UNIV LILLE   (France)

^c TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Dermoid cyst; Hilus cells; Immunohistochemistry; Leydig cells; Lutein cells; Steroid cells; Steroidogenesis

Indexed keywords

ADULT; ARTICLE; FEMALE; HUMAN; HUMAN TISSUE; OVARY CYST; OVARY TUMOR; PRIORITY JOURNAL; STEROIDOGENESIS; TERATOMA; TUMOR CLASSIFICATION; VIRILIZATION;

EID: 0033031527     PISSN: 02771691     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004347-199904000-00013     Document Type: Article

References (20)

1. Rutgers JL, Scully RE. Functioning ovarian tumors with peripheral steroid cell proliferation: a report of twenty-four cases. Int J Gynecol Pathol 1986;5:319-37.
2. Takayama K, Fukaya T, Sasano H, et al. Immunohistochemical study of steroidogenesis and cell proliferation in polycystic ovarian syndrome. Hum Reprod 1996;11:1387-92.
3. Hughesdon PE. Thecal and allied reactions in epithelial ovarian tumors. J Obstet Gynaecol Br Commonw 1958;55:702-9.
4. Case records of the Massachusetts General Hospital. N Engl J Med 1970;282:675-81.
5. Dikman SH, Toker C. Strumal carcinoid of the ovary with masculinization. Cancer 1971;27:925-30.
6. Bulwa FM, Lewis MG. Ovarian teratoma containing arrhenoblastic tissue. J Obstet Gynaecol Br Commonw 1971;78:759-61.
7. Cooke CW, McEvoy D, Wallach EE. Polycystic ovarian syndrome with unilateral cystic teratoma. Obstet Gynecol 1972;39:789-94.
8. Aiman J, Nalick RH, Jacobs A. et al. The origin of androgen and estrogen in a virilized postmenopausal woman with bilateral benign cystic teratomas. Obstet Gynecol 1977;49:695-704.
9. Ishikura H, Sasano H. Histopathologic and immunohistochemical study of steroidogenic cells in the stroma of ovarian tumors. Int J Gynecol Pathol 1998;17:261-5.
10. Robboy SJ, Scully RE. Strumal carcinoid of the ovary: an analysis of 50 cases of a distinctive tumor composed of thyroid tissue and carcinoid. Cancer 1980;46:2019-34.
11. Konishi I, Fujii S, Ishikawa Y, Suzuki A, Okamura H, Mori T. Ovarian fibroma with Leydig cell hyperplasia of the adjacent stroma: a light and electron microscopic study. Int J Gynecol Pathol 1986;5:170-8.
12. Carpen O, Simberg N, Sasano H, Saksela E. Virilizing ovarian leiomyoma: androgen production by lining stromal cells. Acta Obstet Gynecol Scand 1996;75:72-6.
13. Erickson GF. The ovarian connection. In: Adashi EY, Rock JA, Rosenwaks Z, eds. Reproductive Endocrinology, Surgery, and Technology. Philadelphia: Lippincott, 1996:1142-60.
14. Matias-Guiu X, Prat J. Ovarian tumors with functioning stroma: an immunohistochemical study of 100 cases with human chorionic gonadotropin monoclonal and polyclonal antibodies. Cancer 1990; 65:2001-5.
15. Goudas VT, Wasty F, Pardanani B, Ying YK. Testosterone-producing solitary ovarian cyst with luteinized stromal-cell hyperplasia. Obstet Gynecol 1996;87:870-2.
16. Rajaniemi H, Kauppila A, Ronnberg L, Selander K, Pystynen P. LH(hCG) receptor in benign and malignant tumors of human ovary. Acta Obstet Gynecol Scand Suppl 1981;101:83-6.
17. Teerds KJ, Dorrington JH. Immunolocalization of transforming growth factor alpha and luteinizing hormone receptor in healthy and atretic follicles of the adult rat ovary. Biol Reprod 1995;52: 500-8.
18. Morohashi KI, Omura T. Ad4BP/SF-1, a transcription factor essential for the transcription of steroidogenic cytochrome P450 genes and for the establishment of the reproductive function. FASEB J 1996;10:1569-77.
19. Kobayashi T, Nakamura M, Kajiura-Kobayashi H, Young G, Nagahama Y. Immunolocalization of steroidogenic enzymes (P450scc, p450c17, p450arom, and 3beta-HSD) in immature and mature testes of rainbow trout. Cell Tissue Res 1998;292:573-7.
20. Sasano H. Localization of steroidogenic enzymes in adrenal cortex and its disorders. Endocr J 1994;41:471-82.