Atorvastatin, an HMG-CoA reductase inhibitor and effective lipid-regulating agent. Part II: Synthesis of side-chain-labeled [14C]atorvastatin

Journal of Labelled Compounds and Radiopharmaceuticals

Volumn 42, Issue 2, 1999, Pages 129-133

  Lee, Helen T ^a   Woo, Peter W K ^a  

^a PFIZER INC   (United States)

Author keywords

14C side chain labeled atorvastatin; Atherosclerosis; HMG CoA reductase inhibitor; Hypocholesterolemia agent; Lipitor

Indexed keywords

CHAINS; CHLORINE COMPOUNDS; CONDENSATION; KETONES; SODIUM COMPOUNDS;

14C SIDE-CHAIN LABELED ATORVASTATIN; ATHEROSCLEROSE; ATORVASTATIN; HMG-COA REDUCTASE INHIBITOR; HYPOCHOLESTEROLEMIUM AGENT; LIPID REGULATING AGENTS; LIPITOR®; SIDE-CHAINS; SYNTHESISED; TEN STEPS;

ESTERS;

ACETIC ACID; ALDEHYDE; ATORVASTATIN; CALCIUM SALT; CARBON 14; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; KETOL; LACTONE; TERT BUTYL LITHIOACETATE; UNCLASSIFIED DRUG;

ARTICLE; CRYSTALLIZATION; DIASTEREOISOMER; DRUG SYNTHESIS; ESTERIFICATION; ISOTOPE LABELING;

EID: 0033031406     PISSN: 03624803     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-1344(199902)42:2<129::AID-JLCR174>3.0.CO;2-O     Document Type: Article

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