Cell specific cytotoxicity and structure-activity relationship of lipophilic 1-B-D-arabinofuranosylcytosine (ara-C) derivatives

Nucleosides and Nucleotides

Volumn 18, Issue 4-5, 1999, Pages 877-878

  Peters, G J ^a   Voorn, D A ^b,c   Kuiper, C M ^b,c   Van Der Wilt, C L ^b,c   Noordhuis, P ^b,c   Smid, K ^b,c   Myhren, F ^b,c   Sandvold, M ^b,c   Hendriks, H R ^b,c  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^b STATOIL   (Norway)

^c EORTC NDDO   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CYTARABINE DERIVATIVE; DEOXYCYTIDINE KINASE; GEMCITABINE;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; CHEMICAL BOND; CONFERENCE PAPER; DRUG CYTOTOXICITY; DRUG PENETRATION; DRUG RETENTION; DRUG STRUCTURE; ENZYME ACTIVITY; ESTERIFICATION; LEUKEMIA CELL LINE; NONHUMAN; OVARY CANCER; RAT; STRUCTURE ACTIVITY RELATION;

ANIMALIA; ARA;

EID: 0033031382     PISSN: 07328311     EISSN: None     Source Type: Journal    
DOI: 10.1080/15257779908041589     Document Type: Conference Paper

References (4)

1. Peters GJ, Jansen G. Resistance to antimetabolites. In: Principles Antineoplastic Drug Development and Pharmacology (Schilsky RL et al) Marcel Dekker, 1996, 543-585.
2. Bergman AM, Pinedo HM, Jongsma APM, Brouwer M, Ruiz van Haperen VWT, Veerman G, Leyva A, Peters GJ. Biochem. Pharmacol. 1998, in press
3. Ruiz van Haperen VWT, Veerman G, Van Moorsel CJA, Peters GJ. Adv. Exp. Med. Biol. 1998, 431, 637-640.
4. Ruiz van Haperen VWT, Veerman G, Eriksson S, Boven E, Stegmann APA, Hermsen M, Vermorken JB, Pinedo HM, Peters GJ. Cancer Res.1994, 54; 4138-4143.