Factors influencing the population pharmacokinetic parameters of phenytoin in adult epileptic patients in South Africa

Therapeutic Drug Monitoring

Volumn 21, Issue 1, 1999, Pages 57-62

  Valodia, Praneet ^a   Seymour, Michael A ^b   Miller, Raymond ^e   McFadyen, Margaret L ^c   Folb, Peter I ^d  

^a UNIVERSITY OF THE WESTERN CAPE   (South Africa)

^b Warner Lambert Pty Ltd   (South Africa)

^c UNIVERSITY OF KWAZULU NATAL   (South Africa)

^d UNIVERSITY OF CAPE TOWN   (South Africa)

^e CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

Patient factors; Phenytoin; Population pharmacokinetic parameters

Indexed keywords

PHENYTOIN;

ADOLESCENT; ADULT; AGE; AGED; ARTICLE; BODY WEIGHT; DRUG BLOOD LEVEL; DRUG ELIMINATION; DRUG METABOLISM; EPILEPSY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; METABOLIC RATE; MICHAELIS CONSTANT; PRIORITY JOURNAL; RACE DIFFERENCE; SMOKING; STEADY STATE;

ADOLESCENT; ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; ALCOHOL DRINKING; AMINO ACID SEQUENCE; ANTICONVULSANTS; BASE SEQUENCE; BODY WEIGHT; EPILEPSY; FEMALE; HUMANS; MALE; MIDDLE AGED; MODELS, STATISTICAL; MOLECULAR SEQUENCE DATA; PHENYTOIN; PROSPECTIVE STUDIES; SEQUENCE ALIGNMENT; SEX FACTORS; SMOKING; SOUTH AFRICA;

EID: 0033031150     PISSN: 01634356     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007691-199902000-00009     Document Type: Article

References (21)

1. Rambeck B, Boenigk HE, Dunlop A, et al. Predicting phenytoin dose: A revised nomogram. Ther Drug Monit 1979;1:325-33.
2. Grasela TH, Sheiner LB, Rambeck B, et al. Steady-state pharmacokinetics of phenytoin from routinely collected patient data. Clin Pharmacokinet 1983;8:355-64.
3. Chan E, Ti TY, Lee HS. Population pharmacokinetics of phenytoin in Singapore Chinese. Eur J Clin Pharmacol 1990;39:177-81.
4. Sheiner LB, Beal SL. Some suggestions for measuring predictive performance. J Pharm Biopharm 1981;94:503-12.
5. Barot MH, Grant RHE, Maheendran KK, et al. Individual variation in daily dosage requirements for phenytoin sodium in patients with epilepsy. Br J Clin Pharmacol 1978;6:267-71.
6. Winter ME, Tozer TN. Phenytoin. In: Evans WE, Schentag JJ, Jusko WJ, eds. Applied pharmacokinetics. Principles of therapeutic drug monitoring. Spokane, WA: Applied Therapeutics, 1987: 493-539.
7. Miller R, Rheeders M, Klein C, et al. Population pharmacokinetics of phenytoin in South African black patients. S Afr Med J 1987; 72:188-90.
8. Sheiner LB, Beal SL. Bayesian individualization of pharmacokinetics: Simple implementation and comparison with non-Bayesian methods. J Pharm Sci 1982;7112:1344-8.
9. Vozeh S, Miur KT, Sheiner LB, et al. Predicting individual phenytoin dosage. J Pharmacokinet Biopharm 1981;92:131-46.
10. Beal SL, Sheiner LB, Boeckmann AJ. NONMEM users guide. San Francisco, CA: NONMEM Project Group, University of California, 1988.
11. Sheiner LB, Beal SL. Evaluation of methods for estimating population pharmacokinetic parameters. I. Michaelis-Menten model: Routine clinical pharmacokinetic data. J Pharmacokinet Biopharm 1980;86:553-71.
12. Yukawa E, Higuchi S, Aoyama T. Population pharmacokinetics of phenytoin from routine clinical data in Japan: An update. Chem Pharm Bull 1990;387:1973-6.
13. Ludden TM, Allen JP, Schneider LW, et al. Rate of phenytoin accumulation in man: A simulation study. J Pharm Biopharm 1978;65:399-415.
14. Ludden TM. Nonlinear pharmacokinetics. Clinical implications. Clin Pharmacokinet 1991;206:429-16.
15. Sheiner LB, Rosenberg B, Marathe VV. Estimation of population characteristics of pharmacokinetic parameters from routine clinical data. J Pharmacokinet Biopharm 1977;55:445-79.
16. Fattinger K, Vozeh S, Ha HR, et al. Population pharmacokinetics of quinidine. Br J Clin Pharmac 1991;31:279-86.
17. Wood AJJ, Zhou HH. Ethnic differences in drug disposition and responsiveness. Clin Pharmacokinet 1991;205:350-73.
18. Kalow W. Ethnic differences in drug metabolism. Clin Pharmacokinet 1982;7:373-400.
19. Bauer LA, Blouin RA. Age and phenytoin kinetics in adult epileptics. Clin Pharmacol Ther 1982;313:301-4.
20. Vozeh S, Katz G, Steiner V, et al. Population pharmacokinetic parameters in patients treated with oral mexiletine. Eur J Clin Pharmacol 1982;23:445-51.
21. Burton ME, Vasko MR, Brater DC. Comparison of drug dosing methods. Clin Pharmacokinet 1985;10:1-37.