The role of lymphocytes, granulocytes, mast cells and their related cytokines in lesional skin of linear IgA bullous dermatosis

British Journal of Dermatology

Volumn 140, Issue 6, 1999, Pages 1072-1078

  Caproni, M ^a   Rolfo, S ^a   Bernacchi, E ^a   Bianchi, B ^a   Brazzini, B ^a   Fabbri, P ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

Author keywords

IgA deposits; Linear IgA bullous dermatosis; Mast cells; Neutrophils; Proinflammatory cytokines; T lymphocytes

Indexed keywords

CD30 ANTIGEN; CD4 ANTIGEN; CYTOKINE; EOSINOPHIL CATIONIC PROTEIN; GAMMA INTERFERON; HLA DR ANTIGEN; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 8; LEUKOCYTE ANTIGEN; MYELOPEROXIDASE; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; ARTICLE; BULLOUS SKIN DISEASE; CELL INFILTRATION; CHILD; CLINICAL ARTICLE; FEMALE; GRANULOCYTE; HUMAN; IMMUNOGLOBULIN DEPOSITION; IMMUNOHISTOCHEMISTRY; IMMUNOPHENOTYPING; INFANT; LYMPHOCYTE; MALE; MAST CELL; PATHOGENESIS; PRIORITY JOURNAL;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANTIGENS, CD30; CD4-POSITIVE T-LYMPHOCYTES; CHILD; CHILD, PRESCHOOL; CYTOKINES; EOSINOPHILS; FEMALE; GRANULOCYTES; HLA-DR ANTIGENS; HUMANS; IMMUNOGLOBULIN A; IMMUNOHISTOCHEMISTRY; IMMUNOPHENOTYPING; INFANT; INTERFERON TYPE II; INTERLEUKINS; LEUKOCYTES; MALE; MAST CELLS; MIDDLE AGED; NEUTROPHILS; SKIN; SKIN DISEASES, VESICULOBULLOUS; T-LYMPHOCYTES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0033031037     PISSN: 00070963     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2133.1999.02904.x     Document Type: Article

References (30)

1. 1 Chorzelski TP, Jablonska S. Beutner EH et al. Linear IgA bullous dermatosis. In: Immunopathology of the Skin (Beutner E, Chorzelski T, Bean S, eds). New York: John Wiley & Sons, 1979.
2. 2 Wojnarowska F, Bhogal BS, Black MM. Chronic bullous disease of childhood and linear IgA disease of adults are IgA 1 mediated diseases. Br J Dermatol 1994; 131: 201-4.
3. 3 Wojnarowska F, Allen J, Kirtschig G. Chronic bullous disease of childhood, childhood cicatricial pemphigoid and linear IgA disease of adults, a comparative study demonstrating clinical and immunological overlap. J Am Acad Dermatol 1988; 19: 792-805.
4. 4 Wojnarowska F, Allen J, Collier P. Linear IgA disease: a heterogeneous disease. Dermatology 1994; 189 (Suppl.): 52-6.
5. 5 Blenkinsopp WK, Fry L, Haffenden GP, Leonard JN. Histology of linear IgA disease, dermatitis herpetiformis, and bullous pemphigoid. Am J Dermatol 1983; 5: 547-54.
6. 6 Zone JJ, Taylor TB, Kadunce DP, Meyer LJ. Identification of the cutaneous basement membrane zone antigen and isolation of antibody in linear immunoglobulin A bullous dermatosis. J Clin Invest 1990; 85: 812-20.
7. 7 Haftek M, Zone JJ, Taylor TB et al. Immunogold localization of the 97-kD antigen of linear IgA bullous dermatosis (LABD) detected with patients' sera. J Invest Dermatol 1994; 103: 656-9.
8. 8 Ishiko A, Shimizu H, Masunaga T et al. 97-kDa linear IgA bullous dermatosis (LAD) antigen localizes to the lamina lucida of the epidermal basement membrane. J Invest Dermatol 1996; 106; 739-43.
9. 9 Wojnarowska F, Whitehead P, Leigh IM et al. Identification of the target antigen in chronic bullous disease of childhood and linear IgA disease of adults. Br J Dermatol 1991; 124: 157-62.
10. 10 Dmochowski M, Hashimoto T, Bhogal BS et al. Immunoblotting studies of linear IgA disease. J Dermatol Sci 1993; 6: 194-200.
11. 11 Ghohestani RF, Nicolas JF, Kanitakis J, Claudy A. Linear IgA bullous dermatosis with IgA antibodies exclusively directed against the 180 or 230kDa epidermal antigens. J Invest Dermatol 1997; 108: 854-8.
12. 12 Zone JJ, Taylor TB, Meyer LJ, Peterson MJ. The 97 kDa linear bullous disease antigen is identical to a portion of the extracellular domain of the 180 kDa bullous pemphigoid antigen, BPAg2. J Invest Dermatol 1998; 110: 207-10.
13. 13 Dabrowski J, Chorzelski TP, Jablonska S et al. The ultrastructural localization of IgA deposits in chronic bullous disease of childhood (CBDC). J Invest Dermatol 1979; 71: 291-5.
14. 14 Bhogal B, Wojnarowska F, Marsden RA et al. Linear IgA bullous dermatosis of adults and children: an immunoelectron microscopic study. Br J Dermatol 1987; 117: 289-96.
15. 15 Prost C, De Leca AC, Combemale P et al. Diagnosis of adult linear IgA dermatosis by immunoelectronmicroscopy in 16 patients with linear IgA deposits. J Invest Dermatol 1989; 93: 39-45.
16. 16 Garioch JJ, Baker BS, Leonard JN, Fry L. T lymphocytes in lesional skin of patients with dermatitis herpetiformis. Br J Dermatol 1994; 131: 822-6.
17. 17 Kaneko F, Minagawa T, Takiguchi Y et al. Role of cell-mediated immune reaction in blister formation of bullous pemphigoid. Dermatology 1992; 184: 34-9.
18. 18 Caproni M, Feliciani C, Fuligni A et al. Th2-like cytokines in dermatitis herpetiformis. Br J Dermatol 1998; 138: 242-7.
19. 19 Smith C, Davis T, Anderson D et al. A receptor for tumor necrosis factor defines an unusual family of cellular and viral proteins. Science 1990; 248: 1019-23.
20. 20 Del Prete G, De Carli M, Almerigogna F et al. Preferential expression of CD30 by human CD4+ T cells producing Th2-type cytokines. FASEB J 1995; 9: 81-6.
21. 21 Akahoshi Y, Kanda G, Anan S, Yoshida H. Dermo-epidermal blister formation by linear IgA dermatosis sera in normal human skin in organ culture. J Dermatol 1987; 14: 352-4.
22. 22 Jordon RE, Kawana S, Fritz KA. Immunopathologic mechanisms in pemphigus and bullous pemphigoid. J Invest Dermatol 1985; 85: 72-8s.
23. 23 Reitamo S, Reunala T, Konttinen YT et al. Inflammatory cells, IgA, C3, fibrin and fibronectin in skin lesions in dermatitis herpetiformis. Br J Dermatol 1981; 105: 167-77.
24. 24 Niwa Y, Sakane T, Shingu M et al. Neutrophil-generated active oxygens in linear IgA bullous dermatosis. Arch Dermatol 1985; 121: 73-8.
25. 25 Mosmann RT, Sad S. The expanding universe of T-cell subsets: Th-1, Th-2 and more. Immunol Today 1996; 17: 138-46.
26. 26 Smith TJ, Weis JH. Mucosal T-cell and mast cells share common adhesion receptors. Immunol Today 1996; 17: 60-3.
27. 27 Möller A, Lippert U, Lessmann D et al. Human mast cells produce IL-8. J Immunol 1993; 6: 3261-6.
28. 28 Erger RA, Casale TB. Interleukin-8 is a potent mediator of eosinophil chemotaxis through endothelium and epithelium. Am J Physiol 1995; 268: L117-22.
29. 29 Caproni M, Palleschi GM, Falcos D et al. Serum eosinophil cationic protein (ECP) in bullous pemphigoid. Int J Dermatol 1995; 34: 177-80.
30. 30 Hendrix JD, Mangum KL, Zone JJ, Gammon WR. Cutaneous IgA deposits in bullous diseases function as ligands to mediate adherence of activated neutrophils. J Invest Dermatol 1990; 94: 667-72.