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Volumn 380, Issue 6, 1999, Pages 679-687

Localization of rat cathepsin K in osteoclasts and resorption pits: Inhibition of bone resorption and cathepsin K-activity by peptidyl vinyl sulfones

Author keywords

Bone resorption; Cathepsin K; Inhibition; Osteoclast; Vinyl sulfone

Indexed keywords

CATHEPSIN K; HYDROLASE INHIBITOR; SULFONE DERIVATIVE;

EID: 0033030776     PISSN: 14316730     EISSN: None     Source Type: Journal    
DOI: 10.1515/BC.1999.084     Document Type: Article
Times cited : (121)

References (45)
  • 2
    • 0019948262 scopus 로고
    • L-trans-Epoxysuccinyl-leucylamido(4-guanidino)butane (E-64) and its analogues as inhibitors of cysteine proteinases including cathepsins B, H and L
    • Barrett, A.J., Kembhavi, A.A., Brown, M.A., Kirschke, H., Knight, C.G., Tamai, M., and Hanada, K. (1982). L-trans-Epoxysuccinyl-leucylamido(4-guanidino)butane (E-64) and its analogues as inhibitors of cysteine proteinases including cathepsins B, H and L. Biochem. J. 201, 189-198.
    • (1982) Biochem. J. , vol.201 , pp. 189-198
    • Barrett, A.J.1    Kembhavi, A.A.2    Brown, M.A.3    Kirschke, H.4    Knight, C.G.5    Tamai, M.6    Hanada, K.7
  • 4
    • 0029996205 scopus 로고    scopus 로고
    • High level expression and crystallization of recombinant human cathepsin S
    • Brömme, D., and McGrath, M.E. (1996). High level expression and crystallization of recombinant human cathepsin S. Protein Sciences 5, 787-791.
    • (1996) Protein Sciences , vol.5 , pp. 787-791
    • Brömme, D.1    McGrath, M.E.2
  • 5
    • 0029310512 scopus 로고
    • Human cathepsin O2, a novel cysteine protease highly expressed in osteoclastomas and ovary. Molecular cloning, sequencing and tissue distribution
    • Brömme, D., and Okamoto, K. (1995). Human cathepsin O2, a novel cysteine protease highly expressed in osteoclastomas and ovary. Molecular cloning, sequencing and tissue distribution. Biol. Chem. Hoppe-Seyler 376, 379-384.
    • (1995) Biol. Chem. Hoppe-Seyler , vol.376 , pp. 379-384
    • Brömme, D.1    Okamoto, K.2
  • 6
    • 0030026637 scopus 로고    scopus 로고
    • Human cathepsin O2, a matrix protein-degrading cysteine protease expressed in osteoclasts. Functional expression of human cathepsin O2 in Spodoptera frugiperda and characterization of the enzyme
    • Brömme, D., Okamoto, K., Wang, B.B., and Biroc, S. (1996). Human cathepsin O2, a matrix protein-degrading cysteine protease expressed in osteoclasts. Functional expression of human cathepsin O2 in Spodoptera frugiperda and characterization of the enzyme. J. Biol. Chem. 271, 2126-2132.
    • (1996) J. Biol. Chem. , vol.271 , pp. 2126-2132
    • Brömme, D.1    Okamoto, K.2    Wang, B.B.3    Biroc, S.4
  • 7
    • 0015984017 scopus 로고
    • Cathepsin B1. A lysosomal enzyme that degrades native collagen
    • Burleigh, M.C., Barrett, A.J., and Lazarus, G.S. (1974). Cathepsin B1. A lysosomal enzyme that degrades native collagen. Biochem. J. 137, 387-398.
    • (1974) Biochem. J. , vol.137 , pp. 387-398
    • Burleigh, M.C.1    Barrett, A.J.2    Lazarus, G.S.3
  • 9
    • 0023607260 scopus 로고
    • The effects of inhibitors of cysteine-proteinases and collagenase on the resorptive activity of isolated osteoclasts
    • Delaisse, J.M., Boyde, A., Maconnachie, E., Ali, N.N., Sear, C.H., Eeckhout, Y., Vaes, G., and Jones, S.J. (1987). The effects of inhibitors of cysteine-proteinases and collagenase on the resorptive activity of isolated osteoclasts. Bone 8, 305-313.
    • (1987) Bone , vol.8 , pp. 305-313
    • Delaisse, J.M.1    Boyde, A.2    Maconnachie, E.3    Ali, N.N.4    Sear, C.H.5    Eeckhout, Y.6    Vaes, G.7    Jones, S.J.8
  • 10
    • 0019156408 scopus 로고
    • Inhibition of bone resorption in culture by inhibitors of thiol proteinases
    • Delaisse, J.M., Eeckhout, Y., and Vaes, G. (1980). Inhibition of bone resorption in culture by inhibitors of thiol proteinases. Biochem. J. 15, 365-368.
    • (1980) Biochem. J. , vol.15 , pp. 365-368
    • Delaisse, J.M.1    Eeckhout, Y.2    Vaes, G.3
  • 11
    • 0025772668 scopus 로고
    • Collagenolytic cysteine proteinases of bone resorption. Cathepsin B, (pro) cathepsin L and a cathepsin L-like 70 kDa proteinase
    • Delaisse, J.M., Ledent, P., and Vaes, G. (1991). Collagenolytic cysteine proteinases of bone resorption. Cathepsin B, (pro) cathepsin L and a cathepsin L-like 70 kDa proteinase. Biochem. J. 279, 167-174.
    • (1991) Biochem. J. , vol.279 , pp. 167-174
    • Delaisse, J.M.1    Ledent, P.2    Vaes, G.3
  • 12
    • 0023424630 scopus 로고
    • Biological activity of chicken calcitonin: Effects on neonatal rat and embryonic chick osteoclasts
    • 1987
    • Dempster, D.W., Murrills, R.J., Horbert, W.R., and Arnett, T.R. (1987). Biological activity of chicken calcitonin: effects on neonatal rat and embryonic chick osteoclasts. (1987). J. Bone Miner. Res. 2, 443-448.
    • (1987) J. Bone Miner. Res. , vol.2 , pp. 443-448
    • Dempster, D.W.1    Murrills, R.J.2    Horbert, W.R.3    Arnett, T.R.4
  • 13
    • 0018567644 scopus 로고
    • A fluorescent assay of proteinases in cultured mammalian cells
    • Dolbeare, F., and Vanderlaan, M. (1979). A fluorescent assay of proteinases in cultured mammalian cells. J. Histochem. Cytochem. 27, 1493-1495.
    • (1979) J. Histochem. Cytochem. , vol.27 , pp. 1493-1495
    • Dolbeare, F.1    Vanderlaan, M.2
  • 14
    • 15844422855 scopus 로고    scopus 로고
    • Cathepsin K, but not cathepsins B, L, or S, is abundantly expressed in human osteoclasts
    • Drake, F.H., Dodds, R.A., James, I.E., Connor, J.R., Debouck, C., Richardson, S. et al. (1996). Cathepsin K, but not cathepsins B, L, or S, is abundantly expressed in human osteoclasts. J. Biol. Chem. 271, 12511-12516.
    • (1996) J. Biol. Chem. , vol.271 , pp. 12511-12516
    • Drake, F.H.1    Dodds, R.A.2    James, I.E.3    Connor, J.R.4    Debouck, C.5    Richardson, S.6
  • 15
    • 0017597522 scopus 로고
    • The action of cathepsin B and collagenolytic cathepsin in the degradation of collagen
    • Etherington, D.J., and Evans, P.J. (1977). The action of cathepsin B and collagenolytic cathepsin in the degradation of collagen. Acta. Biol. Med. Ger. 36, 1555-1563.
    • (1977) Acta. Biol. Med. Ger. , vol.36 , pp. 1555-1563
    • Etherington, D.J.1    Evans, P.J.2
  • 16
    • 0031989102 scopus 로고    scopus 로고
    • Letterto the Editor: Is cathepsin K truly involved in bone resorption?
    • Everts, V. (1998). Letterto the Editor: Is cathepsin K truly involved in bone resorption? J. Bone Miner. Res. 13, 321.
    • (1998) J. Bone Miner. Res. , vol.13 , pp. 321
    • Everts, V.1
  • 17
    • 0023752014 scopus 로고
    • Effects of proteinase inhibitors leupeptin and E-64 on osteoclastic bone resorption
    • Everts, V., Beertsen, W., and Schroder, R. (1988). Effects of proteinase inhibitors leupeptin and E-64 on osteoclastic bone resorption. Calcif. Tissue Int. 43, 172-178.
    • (1988) Calcif. Tissue Int. , vol.43 , pp. 172-178
    • Everts, V.1    Beertsen, W.2    Schroder, R.3
  • 19
    • 0030463939 scopus 로고    scopus 로고
    • Cathepsin K: Isolation and characterization of the murine cDNA and genomic sequence, the homologue of the human pycnodysostosis gene
    • Gelb, B.D., Moissoglu, K., Zhang, J., Martignetti, J.A., Brömme, D., and Desnick, R.J. (1996a). Cathepsin K: Isolation and characterization of the murine cDNA and genomic sequence, the homologue of the human pycnodysostosis gene. Biochem. Mol. Med. 59, 200-206.
    • (1996) Biochem. Mol. Med. , vol.59 , pp. 200-206
    • Gelb, B.D.1    Moissoglu, K.2    Zhang, J.3    Martignetti, J.A.4    Brömme, D.5    Desnick, R.J.6
  • 20
    • 0029809357 scopus 로고    scopus 로고
    • Pycnodysostosis, a lysosomal disease caused by cathepsin K deficiency
    • Gelb, B.D., Shi, G.P., Chapman, H.A., and Desnick, R.J. (1996b). Pycnodysostosis, a lysosomal disease caused by cathepsin K deficiency. Science 273, 1236-1238.
    • (1996) Science , vol.273 , pp. 1236-1238
    • Gelb, B.D.1    Shi, G.P.2    Chapman, H.A.3    Desnick, R.J.4
  • 22
    • 0028831635 scopus 로고
    • Molecular cloning of human cDNA for cathepsin K: Novel cysteine proteinase predominantly expressed in bone
    • Inaoka, T., Bilbe, G., Ishibashi, O., Tezuka, K.I., Kumegawa, M., and Kokubo, T. (1995). Molecular cloning of human cDNA for cathepsin K: Novel cysteine proteinase predominantly expressed in bone. Biochem. Biophys. Res. Commun. 206, 89-96.
    • (1995) Biochem. Biophys. Res. Commun. , vol.206 , pp. 89-96
    • Inaoka, T.1    Bilbe, G.2    Ishibashi, O.3    Tezuka, K.I.4    Kumegawa, M.5    Kokubo, T.6
  • 25
    • 0032080113 scopus 로고    scopus 로고
    • Human cathepsin K cleaves native type I and II collagens at the N-terminal end of the triple helix
    • Kafienah, W., Brömme, D., Buttle, D.J., Croucher, L.J., and Hollander, A.P. (1998). Human cathepsin K cleaves native type I and II collagens at the N-terminal end of the triple helix. Biochem. J. 331, 727-732.
    • (1998) Biochem. J. , vol.331 , pp. 727-732
    • Kafienah, W.1    Brömme, D.2    Buttle, D.J.3    Croucher, L.J.4    Hollander, A.P.5
  • 27
    • 0020080258 scopus 로고
    • Action of rat liver cathepsin L on collagen and other substrates
    • Kirschke, H., Kembhavi, A.A., Bohley, R., and Barrett, A.J. (1982). Action of rat liver cathepsin L on collagen and other substrates. Biochem. J. 201, 367-372.
    • (1982) Biochem. J. , vol.201 , pp. 367-372
    • Kirschke, H.1    Kembhavi, A.A.2    Bohley, R.3    Barrett, A.J.4
  • 28
    • 0345465541 scopus 로고
    • Bone tumors
    • E. Rubenstein and D.D. Federman, eds. (New York: Scientific American, Inc.)
    • Krane, S.M., and Simon, L. (1994). Bone tumors. In: Scientific American Medicine, E. Rubenstein and D.D. Federman, eds. (New York: Scientific American, Inc.), pp. 1-26.
    • (1994) Scientific American Medicine , pp. 1-26
    • Krane, S.M.1    Simon, L.2
  • 29
    • 0003990925 scopus 로고
    • Cambridge, U.K.: Elsevier Biosoft
    • Leatherbarrow, R. J. (1987). Enzfitter. (Cambridge, U.K.: Elsevier Biosoft).
    • (1987) Enzfitter
    • Leatherbarrow, R.J.1
  • 31
    • 0031081303 scopus 로고    scopus 로고
    • Localization of cathepsin K in human osteoclasts by in situ hybridization and immunohistochemistry
    • Littlewood-Evans, A., Kokubo, T., Ishibashi, O., Inaoka, T., Wlodarski, B., Gallagher, J.A., and Bilbe, G. (1997). Localization of cathepsin K in human osteoclasts by in situ hybridization and immunohistochemistry. Bone 20, 81-86.
    • (1997) Bone , vol.20 , pp. 81-86
    • Littlewood-Evans, A.1    Kokubo, T.2    Ishibashi, O.3    Inaoka, T.4    Wlodarski, B.5    Gallagher, J.A.6    Bilbe, G.7
  • 33
    • 0030949702 scopus 로고    scopus 로고
    • Effects of an inhibitor of cathepsin L on bone resorption in thyroparathy-roidectomized and ovariectomized rats
    • Millest, A.J., Breen, S.A., Loveday, B.E., Clarkson, RN., Simpson, C.A., Waterton, J.C., and Johnstone, D. (1997). Effects of an inhibitor of cathepsin L on bone resorption in thyroparathy-roidectomized and ovariectomized rats. Bone 5, 465-471.
    • (1997) Bone , vol.5 , pp. 465-471
    • Millest, A.J.1    Breen, S.A.2    Loveday, B.E.3    Clarkson, R.N.4    Simpson, C.A.5    Waterton, J.C.6    Johnstone, D.7
  • 34
    • 0031127998 scopus 로고    scopus 로고
    • Immunocytochemical study of cathepsin L and rat salivary cystatin-3 in rat osteoclasts treated with E-64 in vivo
    • Moroi, R., and Yamaza, T.N.T., Nishimura, Y., Terada, Y., Abe, K., Himeno, M., Tanaka, T. (1997). Immunocytochemical study of cathepsin L and rat salivary cystatin-3 in rat osteoclasts treated with E-64 in vivo. Arch. Oral. Biol. 42, 305-315.
    • (1997) Arch. Oral. Biol. , vol.42 , pp. 305-315
    • Moroi, R.1    Yamaza, T.N.T.2    Nishimura, Y.3    Terada, Y.4    Abe, K.5    Himeno, M.6    Tanaka, T.7
  • 35
    • 0029099619 scopus 로고
    • Vinyl sulfones as mechanism-based cysteine protease inhibitors
    • Palmer, J.T., Rasnick, D., Klaus, J.L., and Brömme, D. (1995). Vinyl sulfones as mechanism-based cysteine protease inhibitors. J. Med. Chem. 38, 3193-3196.
    • (1995) J. Med. Chem. , vol.38 , pp. 3193-3196
    • Palmer, J.T.1    Rasnick, D.2    Klaus, J.L.3    Brömme, D.4
  • 38
    • 0027340176 scopus 로고
    • Cysteine-proteinases localization in osteoclasts: An immunocytochemical study
    • Sasaki, T., and Ueno-Matsuda, E. (1993). Cysteine-proteinases localization in osteoclasts: An immunocytochemical study. Cell Tissue Res. 271, 177-179.
    • (1993) Cell Tissue Res. , vol.271 , pp. 177-179
    • Sasaki, T.1    Ueno-Matsuda, E.2
  • 39
    • 0028835637 scopus 로고
    • Molecular cloning of human cathepsin O, a novel endoproteinase and homologue of rabbit OC2
    • Shi, G.P., Chapman, H.A., Bhairi, S.M., DeLeeuw, C., Reddy, V.Y., and Weiss, S.J. (1995). Molecular cloning of human cathepsin O, a novel endoproteinase and homologue of rabbit OC2. FEBS Lett. 357, 129-134.
    • (1995) FEBS Lett. , vol.357 , pp. 129-134
    • Shi, G.P.1    Chapman, H.A.2    Bhairi, S.M.3    DeLeeuw, C.4    Reddy, V.Y.5    Weiss, S.J.6
  • 42
    • 0023510163 scopus 로고
    • Localization of cathepsin B activity in fibroblasts and chondrocytes by continuous monitoring of the formation of a final fluorescent reaction product using 5-nitrosalicylaldehyde
    • 1987
    • van Noorden, C.J.F., Vogels, I.M., Everts, V., and Beertsen, W. (1987). Localization of cathepsin B activity in fibroblasts and chondrocytes by continuous monitoring of the formation of a final fluorescent reaction product using 5-nitrosalicylaldehyde. (1987). Histochem. J. 19, 483-487.
    • (1987) Histochem. J. , vol.19 , pp. 483-487
    • Van Noorden, C.J.F.1    Vogels, I.M.2    Everts, V.3    Beertsen, W.4
  • 43
    • 0026201987 scopus 로고
    • Molecular recognition and targeting of lysosomal proteins
    • von Figura, K. (1991). Molecular recognition and targeting of lysosomal proteins. Curr. Opin. Cell. Biol. 3, 642-646.
    • (1991) Curr. Opin. Cell. Biol. , vol.3 , pp. 642-646
    • Von Figura, K.1
  • 44
    • 0029175644 scopus 로고
    • Protein sorting signals: Simple peptides with complex functions
    • 1995
    • von Heijne, G. (1995). Protein sorting signals: simple peptides with complex functions. (1995). EXS 73, 67-76.
    • (1995) EXS , vol.73 , pp. 67-76
    • Von Heijne, G.1
  • 45
    • 0030869303 scopus 로고    scopus 로고
    • Peptide aldehyde inhibitorl 11 s of cathepsin K inhibit bone resorption both in vitro and in vivo
    • Votta, B.J., Levy, M.A., Badger, A., Bradbeer, J., Dodds, R.A., James, I.E. et al. (1997). Peptide aldehyde inhibitorl 11 s of cathepsin K inhibit bone resorption both in vitro and in vivo. J. Bone Mineral Res. 12, 1396-1406.
    • (1997) J. Bone Mineral Res. , vol.12 , pp. 1396-1406
    • Votta, B.J.1    Levy, M.A.2    Badger, A.3    Bradbeer, J.4    Dodds, R.A.5    James, I.E.6


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