Adding clonidine to lidocaine for intravenous regional anesthesia prevents tourniquet pain

Anesthesia and Analgesia

Volumn 88, Issue 6, 1999, Pages 1327-1330

  Gentili, Marc ^a   Bernard, Jean Marc ^b   Bonnet, Francis ^c  

^a Clinique Saint Vincent   (France)

^b Polyclinique Jean Villar ^*  (France)

^c HÔPITAL TENON   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; CLONIDINE; LIDOCAINE; LOCAL ANESTHETIC AGENT;

ADULT; AGED; ARTICLE; CARPAL TUNNEL SYNDROME; CLINICAL ARTICLE; CLINICAL TRIAL; COMPRESSION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFECT; HAND SURGERY; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; LOCAL ANESTHESIA; PAIN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; REGIONAL ANESTHESIA; TREATMENT OUTCOME;

EID: 0033030284     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000539-199906000-00024     Document Type: Article

References (13)

1. Hutchinson DT, McClinton MA. Upper extremity tourniquet tolerance. J Hand Surg Am 1993;18:206-10.
2. De Jong RH, Cullen SC. Theoretical aspects of bizarre pain phenomena during low spinal anesthesia. Anesthesiology 1963; 24:628-35.
3. Crews JC, Hilgenhurst G, Leavitt B, et al. Tourniquet pain: the response to the maintenance of tourniquet inflation on the upper extremity in volunteers. Reg Anesth 1991;16:314-7.
4. Picard PR, Tramer MR, McQuay HJ, Moore RA. Analgesic efficacy of peripheral opioids (all except intra-articular): a quantitative systematic review of randomised controlled trials. Pain 1997;72:309-18.
5. 2-adrenergic agonists clonidine and guanfacine produce tonic and phasic block of conduction in rat sciatic nerve fibers. Anesth Analg 1993;76:295-301.
6. Gaumann DE, Brunet P, Jirounek P. Clonidine enhances the effects of lidocaine on C-fiber action potential. Anesth Analg 1992;74:719-25.
7. Bonnet F, Diallo A, Saada M, et al. Prevention of tourniquet pain by spinal isobaric bupivacaine with clonidine. Br J Anaesth 1989;63:93-6.
8. Liu S, Chiu AA, Neal JM, et al. Oral clonidine prolongs lidocaine spinal anesthesia in human volunteers. Anesthesiology 1995;82: 1353-9.
9. Murata K, Nakagawa I, Kumeta Y, et al. Intrathecal clonidine suppresses noxiously evoked activity of spinal wide dynamic range neurons in cats. Anesth Analg 1989;69:185-91.
10. Sato J, Perl ER. Adrenergic excitation of cutaneous pain receptors induced by peripheral nerve injury. Science 1991;251: 1608-10.
11. Reuben SS, Klatt ML, Klatt JL, et al. Intravenous regional anesthesia with lidocaine and clonidine [abstract]. Anesthesiology 1998;89:857.
12. Hoffmann V, Vercauteren M, Van Steenberge A, Adriansen H. Intravenous regional anaesthesia: evaluation of four different additives to prilocaine. Acta Anaesthesiol Belg 1997;48:71-6.
13. Kleinschmidt S, Stöckl W, Wilhelm W, Larsen R. The addition of clonidine to prilocaine for regional anaesthesia. Eur J Anaesthesiol 1997;14:40-6.