Synthesis and antileishmanial activity of α-cyano ethyl propenoates - A new class of antileishmanials

Arzneimittel-Forschung/Drug Research

Volumn 49, Issue 2, 1999, Pages 144-148

  Tiwari, Suman ^a   Gupta, Suman ^a   Tripathi, Rama P ^a   Khan, Abdul R ^a   Katiyar, Jagdish Chandra ^a   Bhaduri, Amiya P ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

Antileishmanial activity; Antiparasitic agents; Leishmania donovani; Synthesis; Cyano ethyl propenoates

Indexed keywords

ACETIC ACID DERIVATIVE; ACRYLIC ACID DERIVATIVE; ALPHA CYANOETHYL PROPENOIC ACID DERIVATIVE; ANTILEISHMANIAL AGENT; UNCLASSIFIED DRUG;

ANTIPROTOZOAL ACTIVITY; ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS; HAMSTER; INTRAMUSCULAR DRUG ADMINISTRATION; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; POLYMERIZATION; PROTON NUCLEAR MAGNETIC RESONANCE;

EID: 0033030167     PISSN: 00044172     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0031-1300375     Document Type: Article

References (16)

1. Anon., WHO Techn. Rep. Ser. 101, 1 (1984)
2. Berman, J. D., Lee, L. S., Robins, R. K. et al., Anti-microb. Agents Chemother. 24, 233 (1988)
3. Croft, S. L., TIPS 91, 376 (1988)
4. Wright, E. P., El-Amin, E. R. M., Biochem. Cell Biol. 67, 525 (1989)
5. Elion, G. H., Kovinsky, A., Hitchings, G. H., Biochem. Pharmacol. 15, 863 (1966)
6. Thakur, C. P., Trans. Roy. Soc. Trop. Med. Hyg. 80, 872 (1986)
7. Jacobson, M. D., TIBS 21, 83 (1996)
8. Fazilamb, A. H., Blackburn, P., Ulrich, P. et al, Science 227, 1485 (1985)
9. Walsh, C., Bradley, M., Nadeau, K., TIBS 16, 305 (1991)
10. Elizabeth, A. K., Philip, T., Stambleton, D. et al., J. Med. Chem. 39, 4608 (1996)
11. Erich, B., Sjogren, M. A., Rider, P. et al., J. Med. Chem. 34, 3295 (1991)
12. Srivastava, A. K., Tripathi, R. P., Khan, A. R. et al., Ind. J. Parasit, 18, 127 (1994)
13. Steck, E. A., in: Progress in Drug Res, E. Jucker (ed.), p. 289, Birkhäuser Verlag, Basel (1974)
14. Gupta, S., Zehra, K., Nigam, V. et al., Ind. J. Parasit. 16, 1 (1992)
15. Schvartzapel, A. J., Zhong, L., Docampo, R. et al., J. Med. Chem. 46, 2314 (1997)
16. Schvartzapel, A. J., Fichera, L., Esteva, M. et al., Helv. Chem. Acta 78, 1207 (1995)