메뉴 건너뛰기




Volumn 50, Issue 2, 1999, Pages 169-181

A new ulcer model, 'unhealed gastric ulcers', induced by chronic treatment with indomethacin in rats with acetic acid ulcers

Author keywords

'unhealed gastric ulcer'; Acetic acid ulcer; Acid pump inhibitor; Indomethacin; Sucralfate

Indexed keywords

ALUMINUM HYDROXIDE; CIMETIDINE; INDOMETACIN; OMEPRAZOLE; SUCRALFATE;

EID: 0033030087     PISSN: 08675910     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (7)

References (26)
  • 1
    • 0014575559 scopus 로고
    • A new method for the production of chronic gastric ulcer in rats and the effect of several drugs on its healing
    • Takagi K, Okabe S, Saziki R. A new method for the production of chronic gastric ulcer in rats and the effect of several drugs on its healing. Jpn J Pharmacol 1969; 19: 418-426.
    • (1969) Jpn J Pharmacol , vol.19 , pp. 418-426
    • Takagi, K.1    Okabe, S.2    Saziki, R.3
  • 2
    • 0015023481 scopus 로고
    • A method for experimental, penetrating gastric and duodenal ulcers in rats
    • Okabe S, Roth JLA, Pfeiffer CJ. A method for experimental, penetrating gastric and duodenal ulcers in rats. Am J Dig Dis 1971; 16: 277-284.
    • (1971) Am J Dig Dis , vol.16 , pp. 277-284
    • Okabe, S.1    Roth, J.L.A.2    Pfeiffer, C.J.3
  • 4
    • 0024523246 scopus 로고
    • Antisecretory and antiulcer activities of a novel proton pump inhibitor AG-1749 in dogs and rats
    • Satoh H, Inatomi N, Nagaya et al. Antisecretory and antiulcer activities of a novel proton pump inhibitor AG-1749 in dogs and rats. J Pharmacol Exp Ther 1989; 248: 806-815.
    • (1989) J Pharmacol Exp Ther , vol.248 , pp. 806-815
    • Satoh, H.1    Inatomi, N.2    Nagaya3
  • 5
    • 0027191940 scopus 로고
    • Effect of NC-1300-O-3 on healing of acetic acid-induced gastric ulcers in rats
    • Okabe S, Takagi K, Inoue K. Effect of NC-1300-O-3 on healing of acetic acid-induced gastric ulcers in rats. Jpn J Pharmacol 1993; 62: 25-33.
    • (1993) Jpn J Pharmacol , vol.62 , pp. 25-33
    • Okabe, S.1    Takagi, K.2    Inoue, K.3
  • 6
    • 15144350829 scopus 로고    scopus 로고
    • Role of endogenous basic fibroblast growth factor in the healing of gastric ulcers in rats
    • Satoh H, Sato F, Asano S, et al. Role of endogenous basic fibroblast growth factor in the healing of gastric ulcers in rats. Jpn J Pharmacol 1997; 73: 59-71.
    • (1997) Jpn J Pharmacol , vol.73 , pp. 59-71
    • Satoh, H.1    Sato, F.2    Asano, S.3
  • 7
    • 0020075971 scopus 로고
    • Influence of non-steroidal anti-inflammatory compounds on healing of chronic gastric ulcers in rats
    • Szelenyi I, Engler H, Herzog P, Postius S, Vergin H, Holtermuller KH. Influence of non-steroidal anti-inflammatory compounds on healing of chronic gastric ulcers in rats. Agents Actions 1980; 12: 180-182.
    • (1980) Agents Actions , vol.12 , pp. 180-182
    • Szelenyi, I.1    Engler, H.2    Herzog, P.3    Postius, S.4    Vergin, H.5    Holtermuller, K.H.6
  • 8
    • 0024489353 scopus 로고
    • Delayed healing of acetic acid-induced gastric ulcers in rats by indomethacin
    • Wang JY, Yamasaki S, Takeuchi K, Okabe S. Delayed healing of acetic acid-induced gastric ulcers in rats by indomethacin. Gastroenterology 1989; 96: 393-402.
    • (1989) Gastroenterology , vol.96 , pp. 393-402
    • Wang, J.Y.1    Yamasaki, S.2    Takeuchi, K.3    Okabe, S.4
  • 9
    • 0025831784 scopus 로고
    • Effect of indomethacin on gastric mucosal blood flow around acetic acid-induced gastric ulcers in rats
    • Hirose H, Takeuchi K, Okabe S. Effect of indomethacin on gastric mucosal blood flow around acetic acid-induced gastric ulcers in rats. Gastroenterology 1991; 100: 1259-1265.
    • (1991) Gastroenterology , vol.100 , pp. 1259-1265
    • Hirose, H.1    Takeuchi, K.2    Okabe, S.3
  • 10
    • 0024406133 scopus 로고
    • Effects of NC-1300, a gastric proton pump inhibitor, on healing of acetic acid-induced gastric ulcers in rats
    • Okabe S, Miyake H, Yamasaki S. Effects of NC-1300, a gastric proton pump inhibitor, on healing of acetic acid-induced gastric ulcers in rats. Dig Dis Sci 1989; 34: 1035-1042.
    • (1989) Dig Dis Sci , vol.34 , pp. 1035-1042
    • Okabe, S.1    Miyake, H.2    Yamasaki, S.3
  • 11
    • 0344309720 scopus 로고
    • Effect of indomethacin and prednisolone on connective tissue at the base of acetic acid-induced gastric ulcers in rats
    • A Garner, PE O'Brien (eds). Chichester, Wiley Publishers
    • Ogihara Y, Fuse Y, Okabe S. Effect of indomethacin and prednisolone on connective tissue at the base of acetic acid-induced gastric ulcers in rats. In: Mechanisms of Injury, Protection and Repair of the Upper Gastrointestinal Tract. A Garner, PE O'Brien (eds). Chichester, Wiley Publishers, 1991, pp. 455-465.
    • (1991) Mechanisms of Injury, Protection and Repair of the Upper Gastrointestinal Tract , pp. 455-465
    • Ogihara, Y.1    Fuse, Y.2    Okabe, S.3
  • 12
    • 0344309721 scopus 로고
    • Therapy of gastric ulcer disease
    • D. Hollander D, GNJ Tytgat (eds). New York, Plenum Medical
    • Lam SK. Therapy of gastric ulcer disease. In: Sucralfate. From the basic science to the bedside. D. Hollander D, GNJ Tytgat (eds). New York, Plenum Medical, 1993, pp. 239-247.
    • (1993) Sucralfate. From the Basic Science to the Bedside , pp. 239-247
    • Lam, S.K.1
  • 13
    • 0021028952 scopus 로고
    • Effects of an antiulcer drug, sucralfate (a basic aluminum salt of sulfated disaccharide), on experimental gastric lesion and gastric secretion in rats
    • Okabe S, Takeuchi K, Kunimi H, Kanno M, Kawashima M. Effects of an antiulcer drug, sucralfate (a basic aluminum salt of sulfated disaccharide), on experimental gastric lesion and gastric secretion in rats. Dig Dis Sci 1983; 28: 1034-1042.
    • (1983) Dig Dis Sci , vol.28 , pp. 1034-1042
    • Okabe, S.1    Takeuchi, K.2    Kunimi, H.3    Kanno, M.4    Kawashima, M.5
  • 14
    • 0008182148 scopus 로고
    • Binding of sucralfate to the mucosal surface
    • D. Hollander, GNJ Tytgat (eds). New York, Plenum Medical
    • Morris GP. Binding of sucralfate to the mucosal surface. In: Sucralfate. From the basic science to the bedside. D. Hollander, GNJ Tytgat (eds). New York, Plenum Medical, 1993, pp. 71-82.
    • (1993) Sucralfate. From the Basic Science to the Bedside , pp. 71-82
    • Morris, G.P.1
  • 15
    • 0027320287 scopus 로고
    • Effect and mechanism of sucralfate on healing of acetic acid-induced gastric ulcers in rats
    • Ogihara Y, Okabe S. Effect and mechanism of sucralfate on healing of acetic acid-induced gastric ulcers in rats. J Physiol Pharmacol 1993; 44: 109-118.
    • (1993) J Physiol Pharmacol , vol.44 , pp. 109-118
    • Ogihara, Y.1    Okabe, S.2
  • 17
    • 0002241192 scopus 로고    scopus 로고
    • Modulation of vascular facors by VEGF/VPF (vascular endothelial cell growth factor/vascular permeability factor) is sufficient for chronic ulcer healing and acute gastroprotection
    • Szabo S, Folkman J, Vincze A, Sandor Zs, Gombos Z. Modulation of vascular facors by VEGF/VPF (vascular endothelial cell growth factor/vascular permeability factor) is sufficient for chronic ulcer healing and acute gastroprotection. Gastroenterology 1997; 112: A303.
    • (1997) Gastroenterology , vol.112
    • Szabo, S.1    Folkman, J.2    Vincze, A.3    Sandor, Zs.4    Gombos, Z.5
  • 18
    • 0031715099 scopus 로고    scopus 로고
    • Vascular approach to gastroduodenal ulceration: New studies with endothelins and VEGF
    • Szabo S, Vincze A, Sandor Zs, Gombos Z. Vascular approach to gastroduodenal ulceration: new studies with endothelins and VEGF. Dig Dis Sci 1998; 43: 40S-45S.
    • (1998) Dig Dis Sci , vol.43
    • Szabo, S.1    Vincze, A.2    Sandor, Zs.3    Gombos, Z.4
  • 19
    • 0000384845 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) enhances angiogenesis in injured gastric mucosa and accelerates healing of ethanol-induced erosions
    • Tarnawski A, Sekhon S, Ichikawa Y, Sarfewh IJ. Vascular endothelial growth factor (VEGF) enhances angiogenesis in injured gastric mucosa and accelerates healing of ethanol-induced erosions. Gastroenterology 1998; 114: A307.
    • (1998) Gastroenterology , vol.114
    • Tarnawski, A.1    Sekhon, S.2    Ichikawa, Y.3    Sarfewh, I.J.4
  • 20
    • 0001638062 scopus 로고
    • Sucralfate affinity for fibroblast growth factor
    • Folkman J, Szabo S, Shing Y. Sucralfate affinity for fibroblast growth factor. J Cell Biol 1991; 111:223A.
    • (1991) J Cell Biol , vol.111
    • Folkman, J.1    Szabo, S.2    Shing, Y.3
  • 21
    • 0026070033 scopus 로고
    • Duodenal ulcer: Discovery of a new mechanism and development of angiogenic therapy that accelerates healing
    • Folkman J, Szabo S, Stovroff M. Duodenal ulcer: discovery of a new mechanism and development of angiogenic therapy that accelerates healing. Ann Surg 1991; 214: 414-426.
    • (1991) Ann Surg , vol.214 , pp. 414-426
    • Folkman, J.1    Szabo, S.2    Stovroff, M.3
  • 22
    • 0025171290 scopus 로고
    • Effect of epidermal growth factor in combination with sucralfate or omeprazole on the healing of chronic gastric ulcers in the rat
    • Ito M, Imai S, Joh T et al. Effect of epidermal growth factor in combination with sucralfate or omeprazole on the healing of chronic gastric ulcers in the rat. J Clin Gastroenterol 1990; 12 (suppl 1): S187-S191.
    • (1990) J Clin Gastroenterol , vol.12 , Issue.SUPPL. 1
    • Ito, M.1    Imai, S.2    Joh, T.3
  • 24
    • 0344309717 scopus 로고
    • Stimulation of mucosal prostaglandins by sucralfate
    • D. Hollander, GNJ Tytgat (eds). New York, Plenum Medical
    • Rachmilewitz D. Stimulation of mucosal prostaglandins by sucralfate. In Sucralfate. From the basic science to the bedside. D. Hollander, GNJ Tytgat (eds). New York, Plenum Medical, 1993, pp. 127-140.
    • (1993) Sucralfate. From the Basic Science to the Bedside , pp. 127-140
    • Rachmilewitz, D.1
  • 25
    • 13644281340 scopus 로고
    • Role of vascular factors, including angiogenesis, in the mechanism of action of sucralfate
    • Szabo S, Vattay P, Scarbrough E, Folkman J. Role of vascular factors, including angiogenesis, in the mechanism of action of sucralfate. Am J Med 1991; 91: 158S.
    • (1991) Am J Med , vol.91
    • Szabo, S.1    Vattay, P.2    Scarbrough, E.3    Folkman, J.4
  • 26
    • 0025044894 scopus 로고
    • Effect of omeprazole on the delayed healing of acetic acid-induced gastric ulcers in rats
    • Wang JY, Nagai H, Okabe S. Effect of omeprazole on the delayed healing of acetic acid-induced gastric ulcers in rats. Jpn J Pharmacol 1990; 54: 82-85.
    • (1990) Jpn J Pharmacol , vol.54 , pp. 82-85
    • Wang, J.Y.1    Nagai, H.2    Okabe, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.