Occurrence of monosialosyl pentahexaosylceramide GalNAc-GM1 as specific tumor-associated ganglioside of human head and neck squamous cell carcinomas

Cancer Letters

Volumn 135, Issue 2, 1999, Pages 159-164

  Bolot, Guillaume ^a   David, Marie Jeanne ^b   Kasama, Takeshi ^c   Taki, Takao ^c   Handa, Shizuo ^c   Richard, Michel ^b   Pignat, Jean Christian ^a   Thomas, Luc ^d   Portoukalian, Jacques ^d  

^a CROIX ROUSSE HOSPITAL   (France)

^b EDOUARD HERRIOT HOSPITAL   (France)

^c TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^d UNIVERSITÉ LYON 1   (France)

Author keywords

Head and neck squamous cell carcinomas; Normal tissue; Structural analysis; Tumor associated ganglioside

Indexed keywords

CERAMIDE DERIVATIVE; GANGLIOSIDE;

ARTICLE; CARBOHYDRATE ANALYSIS; CONTROLLED STUDY; GAS LIQUID CHROMATOGRAPHY; HEAD AND NECK CARCINOMA; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LIPID ANALYSIS; MASS SPECTROMETRY; PRIORITY JOURNAL; SQUAMOUS CELL CARCINOMA; THIN LAYER CHROMATOGRAPHY;

CARCINOMA, SQUAMOUS CELL; CHROMATOGRAPHY, GAS; CHROMATOGRAPHY, THIN LAYER; G(M1) GANGLIOSIDE; HEAD AND NECK NEOPLASMS; HUMANS; MASS SPECTROMETRY; N-ACETYLGALACTOSAMINYLTRANSFERASES; NEOPLASM PROTEINS;

EID: 0033028935     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(98)00291-2     Document Type: Article

References (19)

1. Nagai Y., Iwamori M. Cellular biology of gangliosides. Rosenberg A. Biology of the Sialic Acids. 1995;197 Plenum Press, New York.
2. Hakomori S., Kannagi R. Glycosphingolipids as tumor-associated and differentiation markers. J. Natl. Cancer Inst. 71:1993;231-251.
3. Portoukalian J., Zwingelstein G., Abdul-Malak N., Doré J.F. Alterations of gangliosides in plasma and red cells of humans bearing melanoma tumors. Biochem. Biophys. Res. Commun. 85:1978;916-920.
4. Portoukalian J., David M.J., Gain P., Richard M. Shedding of GD2 ganglioside in patients with retinoblastoma. Int. J. Cancer. 53:1993;948-951.
5. Hank J.A., Surtus J., Gan J., Cheu T.-L., Hong R., Tans K., Reisfeld R.A., Seeges R.C., Reynolds G.P., Bauer M., Wiersma S., Hammond D., Scudel P.M. Treatment of neuroblastoma patients with antiganglioside GD2 antibody plus interleukin-2 induces antibody-dependent cellular cytotoxicity against neuroblastoma detected in vitro. J. Immunother. 15:1994;29-37.
6. Portoukalian J., Carrel S., Doré J.F., Rümke P. Humoral immune response in disease-free advanced melanoma patients after vaccination with melanoma-associated gangliosides. Int. J. Cancer. 49:1991;893-899.
7. Bolot G., David M.J., Taki T., Handa S., Kasama T., Richard M., Pignat J.C., Thomas L., Portoukalian J. Analysis of glycosphingolipids of human head and neck carcinomas with comparison to normal tissue. Biochem. Mol. Biol. Int. 1998;. in press.
8. Bouchon B., Portoukalian J., Bornet H. Sex-specific difference in the galabiosylceramide level in the glycosphingolipids of human thyroid. Biochim. Biophys. Acta. 11:1985;415-424.
9. Williams M.A., McCluer R.H. The use of Sep-Pak C18 cartridges during the isolation of gangliosides. J. Neurochem. 35:1980;266-269.
10. Jourdian G.W., Dean L., Roseman S. The sialic acids XI. A periodate-resorcinol method for the quantitative estimation of free sialic acids and their glycosides. J. Biol. Chem. 246:1971;430-435.
11. Carter H.E., Gaver R.C. Improved reagent for trimethylsilylation of sphingolipid bases. J. Lipid Res. 8:1967;391-395.
12. Bouhours J.F., Glickman R.M. Rat intestinal glycolipids. Distribution and biosynthesis of glycolipids and ceramide in villus and crypt cells. Biochim. Biophys. Acta. 441:1976;123-133.
13. Sweeley C.C., Moscatelli E.A. Qualitative microanalysis and estimation of sphingolipid bases. J. Lipid Res. 1:1959;40-47.
14. Taki T., Ishikawa D., Handa S., Kasama T. Direct mass spectrometric analysis of glycosphingolipid transferred to a polyvinylidene difluoride membrane by thin-layer chromatography. Anal. Biochem. 225:1995;24-27.
15. Iwamori M., Nagai Y. Isolation and characterization of a novel ganglioside, monosialosyl pentahexaosyl ceramide from human brain. J. Biochem. 84:1978;1601-1608.
16. Portoukalian J., Bouchon B. Vibrio cholerae neuraminidase hydrolyses all gangliosides, including GM1 and GM2, on thin-layer plates. J Chromatogr. Biomed. Applic. 128:1986;386-392.
17. Kotani M., Ozawa H., Kawashima I., Ando S., Tai T. Generation of one set of monoclonal antibodies specific for a-pathway ganglio-series gangliosides. Biochim. Biophys. Acta. 1117:1992;97-113.
18. Lutz M.S., Jaskiewicz E., Darling D.S., Furukawa K., Young W.W. Jr. Cloned β1-4 N-acetylgalactosaminyl transferase synthesizes GA2 as well as gangliosides GM2 and GD2. J. Biol. Chem. 269:1994;29227-29231.
19. Svennerholm L. The gangliosides. J. Lipid Res. 5:1964;145-155.