Combined administration of IgA and IgG anti-Thy-1 antibodies enhances renal inflammation in rats

Kidney International

Volumn 55, Issue 6, 1999, Pages 2299-2309

  Van Dixhoorn, Mieneke G A ^a,b   Sato, Toshinobu ^a   Muizert, Yvonne ^a   Van Gijlswijk Janssen, Danielle J ^a   De Heer, Emile ^a   Daha, Mohamed R ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b Building 1 ^*  (Netherlands)

Author keywords

Albuminuria; Glomerulonephritis; IgA nephropathy; Immunoglobulin A and G; Microhematuria

Indexed keywords

IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; THYMOCYTE ANTIBODY;

ANIMAL EXPERIMENT; ARTICLE; CLINICAL FEATURE; COMPLEMENT DEPOSITION; HEMATURIA; IMMUNOGLOBULIN A NEPHROPATHY; IMMUNOGLOBULIN DEPOSITION; IMMUNOPATHOGENESIS; KIDNEY INJURY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEINURIA; RAT;

EID: 0033028594     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.1999.00482.x     Document Type: Article

References (37)

1. 1. Berger J, Hinglais N: Les depôts intercapillaires d'IgA-IgG. J Urol Nephrol 74:694-695, 1968
2. 2. Baart De La Faille-Kuyper EH, Kater L, Kooiker CJ, Dorhout Mees EJ: IgA deposits in cutaneous blood vessel walls and mesangium in Henoch-Schönlein syndrome. Lancet 1:892-893, 1973
3. 3. Rodicio JL: Idiopathic IgA nephropathy. Kidney Int 25:717-729, 1984
4. 4. Emancipator SN, Lamm ME: IgA nephropathy: Pathogenesis of the most common form of glomerulonephritis. Lab Invest 60:168-183, 1989
5. 5. D'Amico G: The commonest glomerulonephritis in the world: IgA nephropathy. Q J Med 64:709-727, 1987
6. 6. Emancipator SN, Gallo GR, Lamm ME: Experimental IgA nephropathy induced by oral immunization. J Exp Med 157:572-582, 1983
7. 7. Rifai A, Small PA, Teague PO, Ayoub EM: Experimental IgA nephropathy. J Exp Med 150:1161-1173, 1979
8. 8. Emancipator SN, Gallo GR, Razaboni R, Lamm ME: Experimental cholestasis promotes the deposition of glomerular IgA. Am J Pathol 113:19-25, 1983
9. 9. Roccatello D, Picciotto G, Ropolo R, Coppo R, Quattrocchio G, Cacace G, Molino A, Amoroso A, Baccega M, Isidoro C, Cardosi R, Sena LM, Piccoli G: Kinetics and fate of IgA-IgG aggregates as a model of naturally occuring immune complexes in IgA Nephropathy. Lab Invest 66:86-95, 1992
10. 10. Van Dixhoorn MGA, Gorter A, Sato T, Van Der Wal Am, Van Eendenburg JDH, Rozing J, Daha MR, De Heer E: Induction of microhematuria by an IgA isotype switch variant of a monoclonal anti-Thy-1.1 antibody in the rat. Kidney Int 50:1612-1623, 1996
11. 11. Paul LC, Rennke HG, Milford EL, Carpenter CB: Thy1.1 in glomeruli of rat kidneys. Kidney Int 25:771-777, 1984
12. 12. Dijkstra CD, Döpp EA, Joling P, Kraal G: The heterogeneity of mononuclear phagocytes in lymphoid organs: Distinct macrophage sub populations in the rat recognized by monoclonal antibodies ED1, ED2 and ED3. Immunology 54:589-599, 1985
13. 13. Rits M, Kints JP, Bazin H, Vaerman JP: Rat C3 conversion by rat anti-2,4, dinitrophenyl (DNP) hapten IgA immune precipitates. Scand J Immunol 25:359-366, 1987
14. 14. Eisen HN, Simms ES, Potter M: Mouse myeloma protein with anti-hapten antibody reactivity: The protein produced by plasma cell tumor MOPC315. Biochemistry 7:4126-4130, 1968
15. 15. Williams AF, Galfre G, Milstein C: Analysis of cell surfaces by xenogenic myeloma hybrid antibodies: Differentiation antigens of rat lymphocytes. Cell 12:663-673, 1977
16. 16. Prelich G, Tan C, Kostura M, Mathews MB, So AG, Downey KM, Stillman B: Functional identity of proliferating cell nuclear antigen and a DNA polymerase-δ auxiliary protein. Nature 326: 517-520, 1987
17. 17. Bagchus WM, Hoedemaeker PJ, Rozing J, Bakker WW: Glomerulonephritis induced by monoclonal anti-Thy-1.l antibodies. Lab Invest 55:680-687, 1986
18. 18. Van Den Dobbelsteen MEA, Van Der Woude FJ, Schroeijers WEM, Van Den Wall Bake AWL, Van Es LA, Daha MR: Binding of dimeric-and polymeric IgA to rat renal mesangial cells enhances the release of interleukin 6. Kidney Int 46:512-519, 1994
19. 19. Johnson RJ, Garcia RL, Pritzl P, Alpers CE: Platelets mediate glomerular cell proliferation in immune complex nephritis induced by anti-mesangial cell antibodies in the rat. Am J Pathol 136:369-374, 1990
20. 20. Vleming L-J, Baelde JJ, Westendorp RGJ, Daha MR, Van ES LA, Bruijn JA: The glomerular deposition of PAS positive material correlates with renal function in human kidney disease. Clin Nephrol 47:158-167, 1997
21. 21. Timmerman JJ, Van Dixhoorn MGA, Schraa EO, Gulswijk-JansSen DJ, Muizert Y, Van Es LA, Daha MR: Extra-hepatic C6 is as effective as hepatic C6 in generation of C5b-9 in anti-Thy1.1 nephritis. Kidney Int 51:1788-1796, 1997
22. 22. Hyman LR, Wagnild JP, Beirne GJ, Burkholder PM: Immunoglobulin A distribution in glomerular disease: Analysis of immunofluorescence localization and pathogenic significance. Kidney Int 3:397-402, 1973
23. 23. Syre G: IgA mesangial glomerulonephritis: Significance and pathogenesis of segmental-focal glomerular lesions. Virchows Arch A 402:11-16, 1983
24. 24. Nieuwhof C, Kruytzer M, Frederiks P, Van Breda Vriesman PJC: Chronicity index and mesangial IgG deposition are risk factors for hypertension and renal failure in early IgA nephropathy. Am J Kidney Dis 31:962-970, 1998
25. 25. Emancipator SN, Ovary Z, Lamm ME: The role of mesangial complement in the hematuria of experimental IgA nephropathy. Lab Invest 57:269-276, 1987
26. 26. Genin C, Laurent B, Sabatier JC, Colon S, Berthoux FC: IgA mesangial deposits in C3H/HeJ mice after oral immunization with ferritin or bovine serum albumin. Clin Exp Immunol 63:385-392, 1986
27. 27. Yamamoto T, Wilson CB: Complement dependence of antibody-induced mesangial cell injury in the rat. J Immunol 138:3758-3765, 1987
28. 28. Couser WG, Johnson RJ, Young BA, Yeh CG, Toth CA, Rudolph AR: The effects of soluble recombinant CRI on complement-mediated experimental glomerulonephritis. J Am Soc Nephrol 5:1888-1894, 1995
29. 29. Medgyesi GA, Füst G, Gergely J, Bazin H: Classes and subclasses of rat immunoglobulins: Interaction of the complement system and with staphylococcal protein A. Immunochemistry 15:125-129, 1978
30. 30. Isaacs KL, Miller F: Antigen size and charge in immune complex glomerulonephritis. Am J Pathol 111:298-306, 1983
31. 31. Isaacs KL, Miller F: Role of antigen size and charge in immune complex glomerulonephritis. Lab Invest 47:198-205, 1982
32. 32. Gesualdo L, Lamm ME, Emancipator SN: Defective oral tolerance promotes nephritogenesis in experimental IgA nephropathy induced by oral immunization. J Immunol 145:3684-3691, 1990
33. 33. Wyatt RJ, Julian BA: Activation of complement in IgA nephropathy. Am J Kidney Dis 12:437-442, 1988
34. 34. Rauterberg EW, Lieberknecht HM, Wingen AM, Ritz E: Complement membrane attack (MAC) in idiopathic IgA-glomerulonephritis. Kidney Int 31:820-829, 1987
35. 35. Tomino Y, Funabiki K, Yaguchi Y, Shirato I, Koide H, Furuhata A, Murata Y, Shirai T: Computer imaging analysis of the correlation between intensities of glomerular immune-deposits and the histopathology in patients with IgA nephropathy. Am J Med Sci 302:278-283, 1991
36. 36. Shirai T, Tomino Y, Sato M, Yoshiki T, Itoh T: IgA nephropathy: Clinicopathology and immunopathology. Contrib Nephrol 9:88-100, 1978
37. 37. Tomino Y, Yagame M, Eguchi K, Nomoto Y, Sakai H: Immunofluorescent studies on S-protein in glomeruli from patients with IgA nephropathy. Am J Pathol 129:402-406, 1987