Consistent detection of CALM-AF10 chimaeric transcripts in haematological malignancies with t(10;11)(p13;q14) and identification of novel transcripts

British Journal of Haematology

Volumn 105, Issue 4, 1999, Pages 928-937

  Narita, Masami ^a,b   Shimizu, Kimiko ^a   Hayashi, Yasuhide ^b   Taki, Tomohiko ^b   Taniwaki, Masafumi ^c   Hosoda, Fumie ^a   Kobayashi, Hirofumi ^d   Nakamura, Hideo ^e   Sadamori, Naoki ^e   Ohnishi, Hiroaki ^b   Bessho, Fumio ^b   Yanagisawa, Masayoshi ^b   Ohki, Misao ^a  

^a NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^d Saitama Cancer Centre Hospital   (Japan)

^e NAGASAKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

AF10; CALM; CALM AF10; Haematological malignancy; Translocation

Indexed keywords

ACUTE GRANULOCYTIC LEUKEMIA; ACUTE LYMPHOBLASTIC LEUKEMIA; ADULT; ARTICLE; CELL LINEAGE; CHILD; CHIMERA; CHROMOSOME 10P; CHROMOSOME 11Q; CHROMOSOME TRANSLOCATION 10; CHROMOSOME TRANSLOCATION 11; CLINICAL ARTICLE; FEMALE; HUMAN; IMMUNOPHENOTYPING; MALE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCHOOL CHILD;

ADULT; AMINO ACID SEQUENCE; CHILD; CHROMOSOME BREAKAGE; CHROMOSOMES, HUMAN, PAIR 10; CHROMOSOMES, HUMAN, PAIR 11; FEMALE; HUMANS; IMMUNOPHENOTYPING; IN SITU HYBRIDIZATION, FLUORESCENCE; LEUKEMIA, LYMPHOCYTIC; LEUKEMIA, MYELOID; MALE; MOLECULAR SEQUENCE DATA; ONCOGENE PROTEINS, FUSION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSCRIPTION FACTORS; TRANSLOCATION, GENETIC; TUMOR CELLS, CULTURED;

EID: 0033027052     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.1999.01433.x     Document Type: Article

References (42)

1. Bennett, J.M., Catovsky, D., Daniel, M.T., Flandrin, G., Galton, D.A., Gralnick, H.R. & Sultan, C. (1976) Proposals for the classification of the acute leukaemias. French-American-British (FAB) Cooperative Group. British Journal of Haematology, 33, 451-458.
2. Bennett, J.M., Catovsky, D., Daniel, M.T., Flandrin, G. Galton, D.A., Gralnick, H.R. & Sultan, C. (1985) Proposed revised criteria for the classification of the acute myeloid leukaemia: a report for the French-American-British Cooperative Group. Annals of Internal Medicine, 103, 620-625.
3. Berger, R., Le Coniat, M., Derre, J., Vecchione, D. & Chen, S.J. (1989) Chromosomal rearrangement on chromosome 11q14-q21 in T cell acute lymphoblastic leukemia. Leukemia, 3, 560-562.
4. Berger, R., Le Coniat, M., Flexor, M.A. & Leblanc, T. (1996) Translocation t(10;11) involving the MLL gene in acute myeloid leukemia: importance of fluorescence in situ hybridization (FISH) analysis. Annales de Genetique, 39, 147-151.
5. Beverloo, H.B., Le Coniat, M., Wijsman, J., Lillington, D.M., Bernard, O., de Klein, A., van Wering, E., Welborn, J., Young, B.D., Hagemeijer, A. & Berger, R. (1995) Breakpoint heterogeneity in t(10;11) translocation in AML-M4/M5 resulting in fusion of AF10 and MLL is resolved by fluorescent in situ hybridization analysis. Cancer Research, 55, 4220-4224.
6. Borkhardt, A., Haas, O.A., Strobl, W., Repp, R., Mann, G., Gadner, H. & Lampert, F. (1995) A novel type of MLL/AF10 fusion transcript in a child with acute megakaryocytic leukemia (AML-M7). Leukemia, 9, 1796-1797.
7. Carter, M., Kalwinsky, D.K., Mirro, J.J., Behm, F.G., Head, D., Huddleston, T.F. & Raimondi, S.C. (1991) The t(10;11)(p14;q21) translocation in three children with acute myeloblastic leukemia. Leukemia, 5, 561-565.
8. Chaplin, T., Ayton, P., Bernard, O.A., Saha, V., Della, V.V., Hillion, J., Gregorini, A., Lillington, D., Berger, R. & Young, B.D. (1995a) A novel class of zinc finger/leucine zipper genes identified from the molecular cloning of the t(10;11) translocation in acute leukemia. Blood, 85, 1435-1441.
9. Chaplin, T., Bernard, O., Beverloo, H.B., Saha, V., Hagemeijer, A., Berger, R. & Young, B.D. (1995b) The t(10;11) translocation in acute myeloid leukemia (M5) consistently fuses the leucine zipper motif of AF10 onto the HRX gene. Blood, 86, 2073-2076.
10. Chomczynski, P. & Sacchi, N. (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol chloroform extraction. Analytical Biochemistry, 162, 156-159.
11. Djabali, M., Selleri, L., Parry, P., Bower, M., Young, B.D. & Evans, G.A. (1992) A trithorax-like gene is interrupted by chromosome 11q23 translocations in acute leukaemias. Nature Genetics, 2, 113-118.
12. Dreyling, M.H., Martinez, C.J., Zheng, M., Mao, J., Rowley, J.D. & Bohlander, S.K. (1996) The t(10;11)(p13;q14) in the U937 cell line results in the fusion of the AF10 gene and CALM, encoding a new member of the AP-3 clathrin assembly protein family. Proceedings of the National Academy of Sciences of the United States of America, 95, 4804-4809.
13. Dreyling, M.H., Schrader, K., Fonatsch, C., Schlegelberger, B., Haase, D., Schoch, C., Ludwig, W., Loffler, H., Buchner, T., Wormann, B., Hiddemann, W. & Bohlander, S.K. (1998) MLL and CALM are fused to AF10 in morphologically distinct subsets of acute leukemia with translocation t(10;11): both rearrangements are associated with a poor prognosis. Blood, 91, 4662-4667.
14. Fischkoff, S.A., Testa, J.R. & Schiffer, C.A. (1988) Acute cosinophilic leukemia with a (10;11) chromosomal translocation. Leukemia, 2, 394-397.
15. Groupe Francais de Cytogenetique Hematologique (1991) t(10;11)(p13-14;q14-21): a new recurrent translocation in T-cell acute lymphoblastic leukemias. Genes, Chromosomes and Cancer, 3, 411-415.
16. Gu, Y., Nakamura, T., Alder, H., Prasad, R., Canaani, O., Cimino, G., Croce, C.M. & Canaani, E. (1992) The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene. Cell, 71, 701-708.
17. Hirose, M., Minato, K., Tobinai, K., Shimoyama, M., Watanabe, S. & Abe, T. (1982) A novel monocytoid cultured cell line, P31/Fujioka, derived from acute monoblastic leukemia. Gann, 73, 735-741.
18. Hjorth, S.B., Pallisgaard, N., Gronholm, M., Hokland, P., Clausen, N. & Jorgensen, P. (1997) A novel MLL-AF10 fusion mRNA variant in a patient with acute myeloid leukemia detected by a new asymmetric reverse transcription PCR method. Leukemia, 11, 1588-1593.
19. Hosoda, F., Arai, Y., Kitamura, E., Inazawa, J., Fukushima, M., Tokino, T., Nakamura, Y., Jones, C., Kakazu, N., Abe, T. & Ohki, M. (1997) A complete NotI restriction map covering the entire long arm of human chromosome 11. Genes to Cells, 345-347.
20. Ikushima, S., Yoshihara, T., Fujiwara, F., Todo, S., Misawa, S., Nakagawa, H., Yumura, K., Ha-Kawa, K., Morioka, Y. & Imashuku, S. (1990) Establishment of a monocytoid cell line (KP-MO-TS) from a patient with acute monocytic leukemia and a mediastinal mass. Acta Haematologica Japonica, 53, 678-687.
21. Kaneko, Y., Maseki, N., Takasaki, N., Sakurai, M., Hayashi, Y., Nakazawa, S., Mori, T., Sakurai, M., Takeda, T., Shikano, T. & Hiyoshi, Y. (1986) Clinical and hematologic characteristics in acute leukemia with 11q23 translocations. Blood, 67, 484-491.
22. Kobayashi, H., Thirman, M.J. & Rowley, J.D. (1995) U937 cell line has a t(10;11)(p13-14;q14-21) rather than a deletion of 11q. Genes, Chromosomes and Cancer, 13, 217-218.
23. Kobayashi, H., Hosoda, F., Maseki, N., Sakurai, M., Imashuku, S., Ohki, M. & Kaneko, Y. (1997) Hematologic malignancies with the t(10;11)(p13;q21) have the name molecular event and a variety of morphologic or immunologic phenotypes. Genes, Chromosomes and Cancer, 20, 253-259.
24. Look, A.T. (1997) Oncogenic transcription factors in the human acute leukemias. Science, 278, 1059-1064.
25. Morris, S.A., Schroder, S., Plessmann, U., Weber, K. & Ungewickell, E. (1993) Clathrin assembly protein AP180: primary structure, domain organization and identification of a clathrin binding site. EMBO Journal, 12, 667-675.
26. Rabbitts, T.H. (1994) Chromosomal translocations in human cancer. Nature, 372, 143-149.
27. Raimondi, S.C., Behm, F.G., Roberson, P.K., Pui, C.H., Rivera, G.K., Murphy, S.B. & Williams, D.L. (1988) Cytogenetics of childhood T-cell leukemia. Blood, 72, 1560-1566.
28. Sait, S.N., Dal, C.P. & Sandberg, A.A. (1987) Recurrent involvement of 11q13 in acute nonlymphocytic leukemia. Cancer Genetics and Cytogenetics, 26, 351-354.
29. Secco, C., Wiernik, P.H., Bennett, J.M. & Paietta, E. (1996) Acute leukemia with t(10;11)(p11-p15;q13-q23). Cancer Genetics and Cytogenetics, 86, 31-34.
30. Shimizu, K., Miyoshi, H., Kozu, T., Nagata, J., Enomoto, K., Maseki, N., Kaneko, Y. & Ohki, M. (1992) Consistent disruption of the AML1 gene occurs within a single intron in the t(8;21) chromosomal translocation. Cancer Research, 52, 6945-6948.
31. Shipley, J., Williams, S., O'Byrne, A., Kearney, L., Jones, T., Young, B., Dyer, M., Catovsky, D., Sheer, D. & Gusterson, B. (1995) Characterization of a t(10;11)(p13-14;q14-21) in the monoblastic cell line U937. Genes, Chromosomes and Cancer, 13, 138-142.
32. Silliman, C.C., McGravran, L., Wei, Q., Miller, L.A., Li, S., & Hunger, S.P. (1998) Alternative splicing in wild-type AF10 and CALM cDNAs and in AF10-CALM and CALM-AF10 fusion cDNAs produced by the t(10;11)(p13-14;q14-q21) suggests a potential role for truncated AF10 polypeptides. Leukemia, 12, 1404-1410.
33. Sousa, R., Tannery, N.H., Zhou, S. & Lafer, E.M. (1992) Characterization of a novel synapse-specific protein. I. Developmental expression and cellular localization of the F1-20 protein and mRNA. Journal of Neuroscience, 12, 2130-2143.
34. Sundstrom, C. & Nilsson, K. (1976) Establishment and characterization of a human histiocytic lymphoma cell line (U-937). International Journal of Cancer, 17, 565-577.
35. Taki, T., Shibuya, N., Taniwaki, M., Hanada, R., Morishita, K., Bessho, F., Yanagisawa, M. & Hayashi, Y. (1998) ABI-1, a human homolog to mouse Abl-Interactor 1, fuses the MLL gene in acute myeloid leukemia with t(10;11)(p11.2;q23). Blood, 92, 1125-1130.
36. Tanabe, S., Bohlander, S.K., Vignon, C.V., Espinosa, R.r., Zhao, N., Strissel, P.L., Zeleznik, L.N. & Rowley, J.D. (1996) AF10 is split by MLL and HEAB, a human homolog to a putative Caenorhabditis elegans ATP/GTP-binding protein in an invins(10;11) (p12;q23q12). Blood, 88, 3535-3545.
37. Taniwaki, M., Silverman, G.A., Nishida, K., Horiike, S., Misawa, S., Shimazaki, C., Miura, I., Nagai, M., Abe, M., Fukuhara, S. & Kashima, K. (1995) Translocations and amplification of the BCL2 gene are detected in interphase nuclei of non-Hodgkin's lymphoma by in situ hybridization with yeast artificial chromosome clones. Blood, 86, 1481-1486.
38. Thirman, M.J., Gill, H.J., Burnett, R.C., Mbangkollo, D., McCabe, N.R., Kobayashi, H., Ziemin-van der Poel, S., Kaneko, Y., Morgan, R., Sandberg, A.A., Chaganti, R.S.K., Larson, R.A., Le Beau, M.M., Diaz, M.O. & Rowley, J.D. (1993) Rearrangement of the MLL gene in acute lymphoblastic and acute myeloid leukemias with 11q23 chromosomal translocations. New England Journal of Medicine, 329, 909-914.
39. Tkachuk, D.C., Kohler, S. & Cleary, M.L. (1992) Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias. Cell, 71, 691-700.
40. Ye, W. & Lafer, E.M. (1995) Clathrin binding and assembly activities of expressed domains of the synapse-specific clathrin assembly protein AP-3. Journal of Biological Chemistry, 270, 10933-10939.
41. Zhou, S., Sousa, R., Tannery, N.H. & Lafer, E.M. (1992) Characterization of a novel synapse-specific protein. II. cDNA cloning and sequence analysis of the F1-20 protein. Journal of Neuroscience, 12, 2144-2155.
42. Ziemin-van der Poel, S., McCabe, N.R., Gill, H.J., Espinosa, R.I., Patel, Y., Harden, A., Rubinelli, P., Smith, S.D., LeBeau, M.M., Rowley, J.D. & Diaz, M.O. (1991) Identification of a gene, MLL that spans the breakpoint in 11q23 translocations associated with human leukemias. Proceedings of the National Academy of Sciences of the United States of America, 88, 10735-10739.