메뉴 건너뛰기




Volumn 29, Issue 3, 1999, Pages 452-461

Platelet adhesion receptors: Novel targets for anti-thrombotic therapy

Author keywords

Adhesion receptors; Antithrombotic agents; GP IIb IIIa inhibitors; Platelets; Thrombosis

Indexed keywords

3 [[3 [4 (AMINOIMINOMETHYL)PHENYL] 4,5 DIHYDRO 5 ISOXAZOLYL]ACETAMIDO] N [(3,5 DIMETHYL 4 ISOXAZOLYL)SULFONYL]ALANINE; 3 [[4 [4 [AMINO(ETHOXYCARBONYLIMINO)METHYL]PHENYL] 2 THIAZOLYL](1 ETHOXYCARBONYLMETHYL 4 PIPERIDINYL)AMINO]PROPIONIC ACID ETHYL ESTER; 3 [[4 [[4 (AMINOIMINOMETHYL)PHENYL]AMINO] 1,4 DIOXOBUTYL]AMINO] 4 PENTYNOIC ACID; 4 (4 AMIDINOBENZOYLGLYCYL) 3 METHOXYCARBONYLMETHYL 2 OXO 1 PIPERAZINEACETIC ACID; 4 [4 [4 (AMINOIMINOMETHYL)PHENYL] 1 PIPERAZINYL] 1 PIPERIDINEACETIC ACID; ABCIXIMAB; ACETYLCYSTEINYLASPARAGINYL 5,5 DIMETHYLTHIOPROLYL 4 AMINOMETHYLPHENYLALANYLGLYCYLASPARTYLCYSTEINE; ACETYLSALICYLIC ACID; ANTITHROMBOCYTIC AGENT; CLOPIDOGREL; EPTIFIBATIDE; FIBRINOGEN RECEPTOR ANTAGONIST; FRADAFIBAN; LAMIFIBAN; LEFRADAFIBAN; N ACETYLCYSTEINYLASPARAGINYLPROLYLARGINYLGLYCYLASPARTYL(O METHYLTYROSYL)ARGINYLCYSTEINAMIDE CYCLIC 1,9 DISULFIDE; N ETHYL N [4 (4 PIPERIDINYL)BUTYRYL]GLYCYLASPARTYL 3 CYCLOHEXYLALANINAMIDE; ORBOFIBAN; SIBRAFIBAN; SKB 214857; TICLOPIDINE; TIROFIBAN; UNCLASSIFIED DRUG; XEMILOFIBAN; YM 35337;

EID: 0033025976     PISSN: 00048291     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1445-5994.1999.tb00742.x     Document Type: Conference Paper
Times cited : (3)

References (61)
  • 1
    • 0000843194 scopus 로고
    • Morphogenesis of occluding coronary artery thrombosis
    • 1. Chapman I. Morphogenesis of occluding coronary artery thrombosis. Arch Pathol 1965; 80: 256-61.
    • (1965) Arch Pathol , vol.80 , pp. 256-261
    • Chapman, I.1
  • 2
  • 3
    • 0026541706 scopus 로고
    • The pathogenesis of coronary artery disease and the acute coronary syndromes
    • 3. Fuster V, Badimon L, Badimon JJ, Chesebro J. The pathogenesis of coronary artery disease and the acute coronary syndromes. N Engl J Med 1992; 326: 310-18.
    • (1992) N Engl J Med , vol.326 , pp. 310-318
    • Fuster, V.1    Badimon, L.2    Badimon, J.J.3    Chesebro, J.4
  • 4
    • 0027513738 scopus 로고
    • Nonatheromatous arterial thrombosis
    • 4. Schafer AI, Kroll MH. Nonatheromatous arterial thrombosis. Ann Rev Med 1993; 44: 155-70.
    • (1993) Ann Rev Med , vol.44 , pp. 155-170
    • Schafer, A.I.1    Kroll, M.H.2
  • 5
    • 0018770590 scopus 로고
    • Human blood platelet adhesion to artery subendothelium is mediated by factor VIII/von Willebrand factor bound to the subendothelium
    • 5. Sakariassan KS, Bolhuis PA, Sixma JJ. Human blood platelet adhesion to artery subendothelium is mediated by factor VIII/von Willebrand factor bound to the subendothelium. Nature 1979; 279: 636-8.
    • (1979) Nature , vol.279 , pp. 636-638
    • Sakariassan, K.S.1    Bolhuis, P.A.2    Sixma, J.J.3
  • 6
    • 13344295095 scopus 로고    scopus 로고
    • Initiation of platelet adhesion by arrest onto fibrinogen or translocation on von Willebrand factor
    • 6. Savage B, Saldivav E, Ruggeri ZM. Initiation of platelet adhesion by arrest onto fibrinogen or translocation on von Willebrand factor. Cell 1996; 84: 289-97.
    • (1996) Cell , vol.84 , pp. 289-297
    • Savage, B.1    Saldivav, E.2    Ruggeri, Z.M.3
  • 7
    • 0031940687 scopus 로고    scopus 로고
    • Selectins and mechanisms of signal transduction
    • 7. Crockett-Torabi E. Selectins and mechanisms of signal transduction. J Leukoc Biol 1998; 63: 1-14.
    • (1998) J Leukoc Biol , vol.63 , pp. 1-14
    • Crockett-Torabi, E.1
  • 8
    • 0031406966 scopus 로고    scopus 로고
    • Selectins, T-cell rolling and inflammation
    • 8. Rossiter H, Alon R, Kupper TS. Selectins, T-cell rolling and inflammation. Mol Med Today 1997; 3: 214-22.
    • (1997) Mol Med Today , vol.3 , pp. 214-222
    • Rossiter, H.1    Alon, R.2    Kupper, T.S.3
  • 9
    • 0025724038 scopus 로고
    • Von Willebrand factor binding to platelet GP Ib initiates signals for platelet activation
    • 9. Kroll MH, Harris TS, Moake JL, Handin RI, Schafer AI. von Willebrand factor binding to platelet GP Ib initiates signals for platelet activation. J Clin Invest 1991; 88: 1568-73.
    • (1991) J Clin Invest , vol.88 , pp. 1568-1573
    • Kroll, M.H.1    Harris, T.S.2    Moake, J.L.3    Handin, R.I.4    Schafer, A.I.5
  • 10
    • 0026766487 scopus 로고
    • Shear stress induced von Willebrand factor binding to platelet glycoprotein Ib initiates calcium influx associated with aggregation
    • 10. Chow TW, Hellums JD, Moake JL, Kroll MH. Shear stress induced von Willebrand factor binding to platelet glycoprotein Ib initiates calcium influx associated with aggregation. Blood 1992; 80: 113-20.
    • (1992) Blood , vol.80 , pp. 113-120
    • Chow, T.W.1    Hellums, J.D.2    Moake, J.L.3    Kroll, M.H.4
  • 11
    • 0027222718 scopus 로고
    • Transmembrane calcium influx associated with von Willebrand factor binding to GP Ib in the initiation of shear-induced platelet aggregation
    • 11. Ikeda Y, Handa M, Kanata T et al. Transmembrane calcium influx associated with von Willebrand factor binding to GP Ib in the initiation of shear-induced platelet aggregation. Thromb Haemost 1993; 69: 496-502.
    • (1993) Thromb Haemost , vol.69 , pp. 496-502
    • Ikeda, Y.1    Handa, M.2    Kanata, T.3
  • 12
    • 0029077090 scopus 로고
    • VCL, an antagonist of the platelet GPIb receptor, markedly inhibits platelet adhesion and intimai thickening after balloon injury in the rat
    • 12. Zahger D, Fishbein MC, Garfinkel LI et al. VCL, an antagonist of the platelet GPIb receptor, markedly inhibits platelet adhesion and intimai thickening after balloon injury in the rat. Circulation 1995; 92: 1269-73.
    • (1995) Circulation , vol.92 , pp. 1269-1273
    • Zahger, D.1    Fishbein, M.C.2    Garfinkel, L.I.3
  • 13
    • 0028240844 scopus 로고
    • Blockade of platelet membrane glycoprotein Ib receptors delays intracoronary thrombogenesis, enhances thrombolysis, and delays coronary artery reocclusion in dogs
    • 13. Yao S-K, Ober JC, Garfinkel LI et al. Blockade of platelet membrane glycoprotein Ib receptors delays intracoronary thrombogenesis, enhances thrombolysis, and delays coronary artery reocclusion in dogs. Circulation 1994; 89: 2822-8.
    • (1994) Circulation , vol.89 , pp. 2822-2828
    • Yao, S.-K.1    Ober, J.C.2    Garfinkel, L.I.3
  • 14
    • 0029798675 scopus 로고    scopus 로고
    • Glycoprotein IIb/IIIa receptor inhibitors: Putting the EPIC, IMPACT II, RESTORE and EPILOG trials into perspective
    • 14. Tcheng JE. Glycoprotein IIb/IIIa receptor inhibitors: putting the EPIC, IMPACT II, RESTORE and EPILOG trials into perspective. Am J Cardiol 1996; (Suppl. 3A) 78: 34-40.
    • (1996) Am J Cardiol , vol.78 , Issue.SUPPL. 3A , pp. 34-40
    • Tcheng, J.E.1
  • 16
    • 0024121629 scopus 로고
    • The α and ß chains of human platelet glycoprotein Ib are both trans-membrane proteins containing a leucine-rich amino acid sequence
    • 16. Lopez JA, Chung DW, Fujikawa K et al. The α and ß chains of human platelet glycoprotein Ib are both trans-membrane proteins containing a leucine-rich amino acid sequence. Proc Natl Acad Sci USA 1988; 85: 2135-9.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 2135-2139
    • Lopez, J.A.1    Chung, D.W.2    Fujikawa, K.3
  • 17
    • 0024728581 scopus 로고
    • Human platelet glycoprotein IX: An adhesive prototype of leucine-rich glycoproteins with flank-center-flank structures
    • 17. Hickey MJ, Williams SA, Roth GJ. Human platelet glycoprotein IX: an adhesive prototype of leucine-rich glycoproteins with flank-center-flank structures. Proc Natl Acad Sci USA 1989; 86: 6773-7.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 6773-6777
    • Hickey, M.J.1    Williams, S.A.2    Roth, G.J.3
  • 18
    • 0025331932 scopus 로고
    • Rapid purification and characterisation of human platelet glycoprotein V: The amino acid sequence contains leucine-rich repetitive modules as in glycoprotein Ib
    • 18. Shimomura T, Fujimara K, Maehama S et al. Rapid purification and characterisation of human platelet glycoprotein V: the amino acid sequence contains leucine-rich repetitive modules as in glycoprotein Ib. Blood 1990; 75: 2349-56.
    • (1990) Blood , vol.75 , pp. 2349-2356
    • Shimomura, T.1    Fujimara, K.2    Maehama, S.3
  • 19
    • 0031886074 scopus 로고    scopus 로고
    • Molecular analysis of the platelet glycoprotein Ib/V/IX receptor
    • 19. Ware J. Molecular analysis of the platelet glycoprotein Ib/V/IX receptor. Thromb Haemost 1998; 79: 466-78.
    • (1998) Thromb Haemost , vol.79 , pp. 466-478
    • Ware, J.1
  • 20
    • 0025253068 scopus 로고
    • Glanzmann's thrombasthenia: The spectrum of clinical disease
    • 20. Caen JP, Nurden AT, George JN. Glanzmann's thrombasthenia: The spectrum of clinical disease. Blood 1990; 75: 1383-95.
    • (1990) Blood , vol.75 , pp. 1383-1395
    • Caen, J.P.1    Nurden, A.T.2    George, J.N.3
  • 22
    • 0021319857 scopus 로고
    • Platelet receptor recognition site on human fibrinogen. Synthesis and structure-function relationship of peptides corresponding to the carboxy-terminal segment of the γ chain
    • 22. Kloczewiak M, Timmons S, Lukas TJ, Hawiger J. Platelet receptor recognition site on human fibrinogen. Synthesis and structure-function relationship of peptides corresponding to the carboxy-terminal segment of the γ chain. Biochemistry 1984; 23: 1767-74.
    • (1984) Biochemistry , vol.23 , pp. 1767-1774
    • Kloczewiak, M.1    Timmons, S.2    Lukas, T.J.3    Hawiger, J.4
  • 23
    • 0026035464 scopus 로고
    • A discrete sequence in platelet integrin is involved in ligand recognition
    • 23. D'Souza SE, Ginsberg MH, Matsueda GR, Plow EF. A discrete sequence in platelet integrin is involved in ligand recognition. Nature 1991; 350: 66-8.
    • (1991) Nature , vol.350 , pp. 66-68
    • D'Souza, S.E.1    Ginsberg, M.H.2    Matsueda, G.R.3    Plow, E.F.4
  • 25
    • 0032523064 scopus 로고    scopus 로고
    • Integrin signalling: The platelet paradigm
    • 25. Shattil SJ, Kashiwagi H, Pampori N. Integrin signalling: the platelet paradigm. Blood 1998; 91: 2645-57.
    • (1998) Blood , vol.91 , pp. 2645-2657
    • Shattil, S.J.1    Kashiwagi, H.2    Pampori, N.3
  • 26
    • 0024462290 scopus 로고
    • Biochemical mechanisms of platelet activation
    • 26. Kroll MH, Schafer AI. Biochemical mechanisms of platelet activation. Blood 1989; 74: 1181-95.
    • (1989) Blood , vol.74 , pp. 1181-1195
    • Kroll, M.H.1    Schafer, A.I.2
  • 27
    • 0023867360 scopus 로고    scopus 로고
    • Secondary prevention of vascular disease by prolonged antiplatelet treatment
    • 27. Antiplatelet Trialists' Collaboration. Secondary prevention of vascular disease by prolonged antiplatelet treatment. Br Med J 1998; 296: 320-31.
    • (1998) Br Med J , vol.296 , pp. 320-331
  • 28
    • 0028120906 scopus 로고
    • Collaborative overview of randomised trials of antiplatelet therapy. I: Prevention of death, myocardial infarction and stroke by prolonged antiplatelet therapy in various categories of patients
    • 28. Antiplatelet Trialists' Collaboration. Collaborative overview of randomised trials of antiplatelet therapy. I: prevention of death, myocardial infarction and stroke by prolonged antiplatelet therapy in various categories of patients. Br Med J 1994; 308: 81-106.
    • (1994) Br Med J , vol.308 , pp. 81-106
  • 29
    • 0032168873 scopus 로고    scopus 로고
    • The antiplatelet effects of ticlopidine and clopidogrel
    • 29. Sharis PJ, Cannon CP, Loscalzo J. The antiplatelet effects of ticlopidine and clopidogrel. Ann Intern Med 1998; 129: 394-405.
    • (1998) Ann Intern Med , vol.129 , pp. 394-405
    • Sharis, P.J.1    Cannon, C.P.2    Loscalzo, J.3
  • 30
    • 0030590746 scopus 로고    scopus 로고
    • A randomised, blinded trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE)
    • 30. CAPRIE steering committee. A randomised, blinded trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE). Lancet 1996; 348: 1329-39.
    • (1996) Lancet , vol.348 , pp. 1329-1339
  • 31
  • 32
    • 0029009904 scopus 로고
    • Antiplatelet drugs. A comparative review
    • 32. Schror K. Antiplatelet drugs. A comparative review. Drugs 1995; 50: 7-28.
    • (1995) Drugs , vol.50 , pp. 7-28
    • Schror, K.1
  • 33
    • 0028354308 scopus 로고
    • Aspirin as an antiplatelet drug
    • 33. Patrono C. Aspirin as an antiplatelet drug. N Engl J Med 1994; 330: 1287-94.
    • (1994) N Engl J Med , vol.330 , pp. 1287-1294
    • Patrono, C.1
  • 34
    • 0027121751 scopus 로고
    • The use of aspirin in ischaemic heart disease
    • 34. Willard JE, Lange RA, Hillis LD. The use of aspirin in ischaemic heart disease. N Engl J Med 1992; 327: 175-81.
    • (1992) N Engl J Med , vol.327 , pp. 175-181
    • Willard, J.E.1    Lange, R.A.2    Hillis, L.D.3
  • 35
    • 0020619733 scopus 로고
    • A murine monoclonal antibody that completely blocks the binding of fibrinogen to platelets produces a thrombasthenic-like state in normal platelets and binds to glycoproteins IIb and/or IIIa
    • 35. Coller BS, Peerschke EI, Scudder LE, Sullivan CA. A murine monoclonal antibody that completely blocks the binding of fibrinogen to platelets produces a thrombasthenic-like state in normal platelets and binds to glycoproteins IIb and/or IIIa. J Clin Invest 1983; 72: 325-38.
    • (1983) J Clin Invest , vol.72 , pp. 325-338
    • Coller, B.S.1    Peerschke, E.I.2    Scudder, L.E.3    Sullivan, C.A.4
  • 36
    • 0028117857 scopus 로고
    • Pharmaco-dynamics of chimeric glycoprotein IIb/IIIa integrin antiplatelet antibody Fab 7E3 in high-risk coronary angioplasty
    • 36. Tcheng JE, Ellis SG, George BS et al. Pharmaco-dynamics of chimeric glycoprotein IIb/IIIa integrin antiplatelet antibody Fab 7E3 in high-risk coronary angioplasty. Circulation 1994; 90: 1757-64.
    • (1994) Circulation , vol.90 , pp. 1757-1764
    • Tcheng, J.E.1    Ellis, S.G.2    George, B.S.3
  • 37
    • 0027320404 scopus 로고
    • Clinical trials of platelet receptor inhibitors
    • 37. Topol EJ, Plow EF. Clinical trials of platelet receptor inhibitors. Thromb Haemost 1993; 70: 94-8.
    • (1993) Thromb Haemost , vol.70 , pp. 94-98
    • Topol, E.J.1    Plow, E.F.2
  • 38
    • 2242477091 scopus 로고
    • Use of a monoclonal antibody directed against the platelet glycoprotein IIb/IIIa receptor in high risk coronary angioplasty
    • 38. The EPIC Investigators. Use of a monoclonal antibody directed against the platelet glycoprotein IIb/IIIa receptor in high risk coronary angioplasty. N Engl J Med 1994; 330: 956-61.
    • (1994) N Engl J Med , vol.330 , pp. 956-961
  • 39
    • 0028910756 scopus 로고
    • Shear-induced platelet aggregation is inhibited by in vivo infusion of an anti-glycoprotein IIb/IIIa antibody fragment, c7E3 Fab, in patients undergoing coronary angioplasty
    • 39. Konstantopoulos K, Kamat SG, Schafer AI et al. Shear-induced platelet aggregation is inhibited by in vivo infusion of an anti-glycoprotein IIb/IIIa antibody fragment, c7E3 Fab, in patients undergoing coronary angioplasty. Circulation 1995; 91: 1427-31.
    • (1995) Circulation , vol.91 , pp. 1427-1431
    • Konstantopoulos, K.1    Kamat, S.G.2    Schafer, A.I.3
  • 40
    • 0028345255 scopus 로고
    • Randomised trial of coronary intervention with antibody against platelet IIb/IIIa integrin for reduction of clinical restenosis: Results at six months
    • 40. Topol EJ, Califf RM, Weismann HF et al., on behalf of the EPIC investigators. Randomised trial of coronary intervention with antibody against platelet IIb/IIIa integrin for reduction of clinical restenosis: results at six months. Lancet 1994; 343: 881-6.
    • (1994) Lancet , vol.343 , pp. 881-886
    • Topol, E.J.1    Califf, R.M.2    Weismann, H.F.3
  • 41
    • 1842369101 scopus 로고    scopus 로고
    • Platelet glycoprotein IIb/IIIa receptor blockade and low-dose heparin during percutaneous coronary revascularization
    • 41. The EPILOG investigators. Platelet glycoprotein IIb/IIIa receptor blockade and low-dose heparin during percutaneous coronary revascularization. N Engl J Med 1997; 336: 1689-96.
    • (1997) N Engl J Med , vol.336 , pp. 1689-1696
  • 42
    • 0023508475 scopus 로고
    • Fibrinogen, fibrinogen receptors and the peptides that inhibit these interactions
    • 42. Plow EF, Marguerie G, Ginsberg M. Fibrinogen, fibrinogen receptors and the peptides that inhibit these interactions. Biochem Pharmacol 1987; 36: 4035-40.
    • (1987) Biochem Pharmacol , vol.36 , pp. 4035-4040
    • Plow, E.F.1    Marguerie, G.2    Ginsberg, M.3
  • 43
    • 0026623091 scopus 로고
    • Cyclic RGD peptide analogues as antiplatelet antithrombotics
    • 43. Barker PL, Bullens S, Bunting S et al. Cyclic RGD peptide analogues as antiplatelet antithrombotics. J Med Chem 1992; 35: 2040-8.
    • (1992) J Med Chem , vol.35 , pp. 2040-2048
    • Barker, P.L.1    Bullens, S.2    Bunting, S.3
  • 44
    • 0021271957 scopus 로고
    • Cell attachment activity of fibronectin can be duplicated by small synthetic fragments of the molecule
    • 44. Pierschbacher MD, Ruoslahti E. Cell attachment activity of fibronectin can be duplicated by small synthetic fragments of the molecule. Nature 1984; 309: 30-3.
    • (1984) Nature , vol.309 , pp. 30-33
    • Pierschbacher, M.D.1    Ruoslahti, E.2
  • 45
    • 0025814801 scopus 로고
    • Arginyl-glycylaspartic acid (RGD): A cell adhesion motif
    • 45. D'Souza SE, Ginsberg MH, Plow EF. Arginyl-glycylaspartic acid (RGD): a cell adhesion motif. Trends Biochem Sci 1991; 16: 246-50.
    • (1991) Trends Biochem Sci , vol.16 , pp. 246-250
    • D'Souza, S.E.1    Ginsberg, M.H.2    Plow, E.F.3
  • 46
    • 0029062761 scopus 로고
    • Mechanisms of Disease: Platelet Glycoprotein IIb/IIIa receptors in cardiovascular medicine
    • 46. Lefkovits J, Plow EF, Topol EJ. Mechanisms of Disease: Platelet Glycoprotein IIb/IIIa receptors in cardiovascular medicine. N Engl J Med 1995; 332: 1553-9.
    • (1995) N Engl J Med , vol.332 , pp. 1553-1559
    • Lefkovits, J.1    Plow, E.F.2    Topol, E.J.3
  • 47
    • 0030919511 scopus 로고    scopus 로고
    • Randomised placebo-controlled trial of effect of eptifibatide on complications of percutaneous coronary intervention: IMPACT-II
    • 47. The IMPACT-II investigators. Randomised placebo-controlled trial of effect of eptifibatide on complications of percutaneous coronary intervention: IMPACT-II. Lancet 1997; 349: 1422-8.
    • (1997) Lancet , vol.349 , pp. 1422-1428
  • 48
    • 0343376106 scopus 로고    scopus 로고
    • Effects of platelet glycoprotein IIb/IIIa blockade with tirofiban on adverse cardiac events in patients with unstable angina or acute myocardial infarction undergoing coronary angioplasty
    • 48. The RESTORE investigators. Effects of platelet glycoprotein IIb/IIIa blockade with tirofiban on adverse cardiac events in patients with unstable angina or acute myocardial infarction undergoing coronary angioplasty. Circulation 1997; 96: 1445-53.
    • (1997) Circulation , vol.96 , pp. 1445-1453
  • 49
    • 2642654221 scopus 로고    scopus 로고
    • A comparison of aspirin plus tirofiban with aspirin plus heparin for unstable angina
    • 49. The platelet receptor inhibition in ischaemic syndrome management (PRISM) study investigators. A comparison of aspirin plus tirofiban with aspirin plus heparin for unstable angina. N Engl J Med 1998; 338: 1498-505.
    • (1998) N Engl J Med , vol.338 , pp. 1498-1505
  • 50
    • 2642599026 scopus 로고    scopus 로고
    • Inhibition of the platelet glycoprotein IIb/IIIa receptor with tirofiban in unstable angina and non Q-wave myocardial infarction
    • 50. The platelet receptor inhibition in ischaemic syndrome management in patients limited by unstable signs and symptoms (PRISM-PLUS) study investigators. Inhibition of the platelet glycoprotein IIb/IIIa receptor with tirofiban in unstable angina and non Q-wave myocardial infarction. N Engl J Med 1998; 338: 1488-97.
    • (1998) N Engl J Med , vol.338 , pp. 1488-1497
  • 51
    • 0030611288 scopus 로고    scopus 로고
    • Glycoprotein IIb/IIIa antagonists: Pathophysiologic and therapeutic insights from studies of c7E3 Fab
    • 51. Coller BS. Glycoprotein IIb/IIIa antagonists: Pathophysiologic and therapeutic insights from studies of c7E3 Fab. Thromb Haemost 1997; 78: 730-5.
    • (1997) Thromb Haemost , vol.78 , pp. 730-735
    • Coller, B.S.1
  • 52
    • 0031974040 scopus 로고    scopus 로고
    • Coronary angioscopic findings in the infarct-related vessel within 1 month of acute myocardial infarction: Natural history and the effect of thrombolysis
    • 52. Van Belle E, Lablanche JM, Beuters C. Renaud N, McFadden EP, Bertrand ME. Coronary angioscopic findings in the infarct-related vessel within 1 month of acute myocardial infarction: natural history and the effect of thrombolysis. Circulation 1998; 97: 26-33.
    • (1998) Circulation , vol.97 , pp. 26-33
    • Van Belle, E.1    Lablanche, J.M.2    Beuters, C.3    Renaud, N.4    McFadden, E.P.5    Bertrand, M.E.6
  • 53
    • 0032562154 scopus 로고    scopus 로고
    • Dissolution of mural thrombosis by specific thrombin inhibition with r-hirudin: Comparison with heparin and aspirin
    • 53. Meyer BJ, Badimon JJ, Chesebro JH, Fallen JT, Fuster V, Badimon L. Dissolution of mural thrombosis by specific thrombin inhibition with r-hirudin: Comparison with heparin and aspirin. Circulation 1998; 97: 681-5.
    • (1998) Circulation , vol.97 , pp. 681-685
    • Meyer, B.J.1    Badimon, J.J.2    Chesebro, J.H.3    Fallen, J.T.4    Fuster, V.5    Badimon, L.6
  • 54
    • 0013609315 scopus 로고    scopus 로고
    • Antithrombotic effect of PEG-hirudin compared to heparin and heparin plus c7E3
    • Abstr.
    • 54. Kyrle PA, Chesebro JH, Hayes RM, Rubsamen K, Fuster V, Badimon JJ. Antithrombotic effect of PEG-hirudin compared to heparin and heparin plus c7E3. Circulation 1997; (Suppl. I) 96: 1-41. (Abstr.).
    • (1997) Circulation , vol.96 , Issue.SUPPL. I , pp. 1-41
    • Kyrle, P.A.1    Chesebro, J.H.2    Hayes, R.M.3    Rubsamen, K.4    Fuster, V.5    Badimon, J.J.6
  • 55
    • 0032578441 scopus 로고    scopus 로고
    • Pharmacodynamic efficacy, clinical safety and outcomes after prolonged platelet glycoprotein IIb/IIIa receptor blockade with oral Xemilofiban. Results of a multicenter, placebo-controlled, randomized trial
    • 55. Kereiakes DJ, Kleinman NS, Ferguson JJ et al. Pharmacodynamic efficacy, clinical safety and outcomes after prolonged platelet glycoprotein IIb/IIIa receptor blockade with oral Xemilofiban. Results of a multicenter, placebo-controlled, randomized trial. Circulation 1998; 98: 1268-78.
    • (1998) Circulation , vol.98 , pp. 1268-1278
    • Kereiakes, D.J.1    Kleinman, N.S.2    Ferguson, J.J.3
  • 56
    • 0032477682 scopus 로고    scopus 로고
    • Oral platelet glycoprotein IIb/IIIa receptor antagonists: The present challenge is safety
    • 56. Vorchheimer DA, Fuster V. Oral platelet glycoprotein IIb/IIIa receptor antagonists: the present challenge is safety. Circulation 1998; 97: 312-14.
    • (1998) Circulation , vol.97 , pp. 312-314
    • Vorchheimer, D.A.1    Fuster, V.2
  • 57
    • 85069245530 scopus 로고    scopus 로고
    • No. 2420, 24-5
    • 57. SCRIP 1999; No. 2420, 24-5.
    • (1999)
  • 58
    • 0031902980 scopus 로고    scopus 로고
    • Comparative studies on the antiplatelet effects of a humanized antiplatelet glycoprotein IIb/IIIa antibody (YM337) and ReoPro under flow conditions
    • 58. Kuwahara M, Sugimoto M, Tsuji S et al. Comparative studies on the antiplatelet effects of a humanized antiplatelet glycoprotein IIb/IIIa antibody (YM337) and ReoPro under flow conditions. Thromb Haemost 1998; 80: 28-31.
    • (1998) Thromb Haemost , vol.80 , pp. 28-31
    • Kuwahara, M.1    Sugimoto, M.2    Tsuji, S.3
  • 59
    • 0022483593 scopus 로고
    • Von Willebrand's disease prevents occlusive thrombosis in stenosed and injured porcine coronary arteries
    • 59. Nichols TC, Bellinger DA, Johnson TA, Lamb MA, Griggs TR. Von Willebrand's disease prevents occlusive thrombosis in stenosed and injured porcine coronary arteries. Circ Res 1986; 59: 15-26.
    • (1986) Circ Res , vol.59 , pp. 15-26
    • Nichols, T.C.1    Bellinger, D.A.2    Johnson, T.A.3    Lamb, M.A.4    Griggs, T.R.5
  • 60
    • 0025328434 scopus 로고
    • Von Willebrand factor and occlusive arterial thrombosis. A study in normal and von Willebrand's disease pigs with diet-induced hypercholesterolemia and artherosclerosis
    • 60. Nichols TC, Bellinger DA, Tate DA, Reddick RL, Read MS, Kock GG, Brinkhous KM, Griggs TR. Von Willebrand factor and occlusive arterial thrombosis. A study in normal and von Willebrand's disease pigs with diet-induced hypercholesterolemia and artherosclerosis. Arteriosclerosis 1990; 10: 449-61.
    • (1990) Arteriosclerosis , vol.10 , pp. 449-461
    • Nichols, T.C.1    Bellinger, D.A.2    Tate, D.A.3    Reddick, R.L.4    Read, M.S.5    Kock, G.G.6    Brinkhous, K.M.7    Griggs, T.R.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.