-
1
-
-
0027123107
-
Molecular and cellular biology and blood coagulation
-
1. Furie B, Furie BC. Molecular and cellular biology and blood coagulation. N Engl J Med 1992; 326: 800-6.
-
(1992)
N Engl J Med
, vol.326
, pp. 800-806
-
-
Furie, B.1
Furie, B.C.2
-
2
-
-
0029160806
-
Advances in antithrombotic drug therapy for coronary artery disease
-
2. Rihal CS, Flather J, Hirsh J, Yusuf S. Advances in antithrombotic drug therapy for coronary artery disease. Eur Heart J 1995; 16: (Suppl. D): 10-21.
-
(1995)
Eur Heart J
, vol.16
, Issue.SUPPL. D
, pp. 10-21
-
-
Rihal, C.S.1
Flather, J.2
Hirsh, J.3
Yusuf, S.4
-
3
-
-
0027409404
-
A player of many parts: The spotlight falls on thrombin's structure
-
3. Stubbs MT, Bode W. A player of many parts: the spotlight falls on thrombin's structure. Thromb Res 1993; 69: 1-58.
-
(1993)
Thromb Res
, vol.69
, pp. 1-58
-
-
Stubbs, M.T.1
Bode, W.2
-
4
-
-
0026780909
-
Antithrombotic effects of synthetic peptides targeting various functional domains of thrombin
-
4. Kelly AB, Maraganore JM, Bourbon P, Hanson SR, Harker LA. Antithrombotic effects of synthetic peptides targeting various functional domains of thrombin. Proc Natl Acad Sci USA 1992; 89: 6040-4.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 6040-6044
-
-
Kelly, A.B.1
Maraganore, J.M.2
Bourbon, P.3
Hanson, S.R.4
Harker, L.A.5
-
5
-
-
0026434005
-
Heparin
-
5. Hirsh J. Heparin. N Engl J Med 1991; 324: 1565-74.
-
(1991)
N Engl J Med
, vol.324
, pp. 1565-1574
-
-
Hirsh, J.1
-
6
-
-
0028593584
-
New anticoagulant strategies - Current status and future potential
-
6. Weitz J. New anticoagulant strategies - current status and future potential. Drugs 1994; 48: 485-97.
-
(1994)
Drugs
, vol.48
, pp. 485-497
-
-
Weitz, J.1
-
7
-
-
0028353572
-
Guide to anticoagulant activity: Part I
-
7. Hirsh J, Fuster V. Guide to anticoagulant activity: Part I. Circulation 1994; 89: 1449-68.
-
(1994)
Circulation
, vol.89
, pp. 1449-1468
-
-
Hirsh, J.1
Fuster, V.2
-
8
-
-
0026593425
-
Low molecular weight heparin
-
8. Hirsh J, Levine MN. Low molecular weight heparin. Blood 1992; 79: 1-17.
-
(1992)
Blood
, vol.79
, pp. 1-17
-
-
Hirsh, J.1
Levine, M.N.2
-
9
-
-
0023754429
-
Aspirin, heparin or both to treat acute unstable angina
-
9. Theroux P, Ouimet H, McCans J, Latour J, Joly P, Levy G. Aspirin, heparin or both to treat acute unstable angina. N Engl J Med 1988; 319: 1105-11.
-
(1988)
N Engl J Med
, vol.319
, pp. 1105-1111
-
-
Theroux, P.1
Ouimet, H.2
McCans, J.3
Latour, J.4
Joly, P.5
Levy, G.6
-
10
-
-
0025090942
-
Risk of myocardial infarction and death during treatment with low dose aspirin and intravenous heparin in men with unstable coronary artery disease
-
10. The RISC group. Risk of myocardial infarction and death during treatment with low dose aspirin and intravenous heparin in men with unstable coronary artery disease. Lancet 1990; 336: 827-30.
-
(1990)
Lancet
, vol.336
, pp. 827-830
-
-
-
11
-
-
0025092298
-
A comparison between heparin and low dose aspirin as adjunctive therapy with tissue plasminogen activator for acute myocardial infarction: Heparin-Aspirin Reperfusion Trial Investigators
-
11. Hsia J, Hamilton WP, Kleimann N, Roberts R, Chaitman BR, Ross AM. A comparison between heparin and low dose aspirin as adjunctive therapy with tissue plasminogen activator for acute myocardial infarction: Heparin-Aspirin Reperfusion Trial Investigators. N Engl J Med 1990; 323: 1433-7.
-
(1990)
N Engl J Med
, vol.323
, pp. 1433-1437
-
-
Hsia, J.1
Hamilton, W.P.2
Kleimann, N.3
Roberts, R.4
Chaitman, B.R.5
Ross, A.M.6
-
12
-
-
0025687989
-
Effect of heparin on coronary artery patency after thrombolysis with tissue plasminogen activator in acute myocardial infarction
-
12. Bleich SD, Nichols TC, Schumacher RR, Cooke DH, Tate DA, Teichman SL. Effect of heparin on coronary artery patency after thrombolysis with tissue plasminogen activator in acute myocardial infarction. Am J Cardiol 1990; 66: 1412-7.
-
(1990)
Am J Cardiol
, vol.66
, pp. 1412-1417
-
-
Bleich, S.D.1
Nichols, T.C.2
Schumacher, R.R.3
Cooke, D.H.4
Tate, D.A.5
Teichman, S.L.6
-
13
-
-
0026537021
-
Effect of early intravenous heparin on coronary patency, infarct size, and bleeding complications after alteplase thrombolysis: Results of a randomised, double-blind European cooperative study group trial
-
13. De Bono DP, Simoons ML, Tijssen J et al., and the European Cooperative Study Group. Effect of early intravenous heparin on coronary patency, infarct size, and bleeding complications after alteplase thrombolysis: results of a randomised, double-blind European cooperative study group trial. Br Heart J 1992; 67: 122-8.
-
(1992)
Br Heart J
, vol.67
, pp. 122-128
-
-
De Bono, D.P.1
Simoons, M.L.2
Tijssen, J.3
-
14
-
-
0029938993
-
Activated partial thromboplastin time and outcome after thrombolytic therapy for acute myocardial infarction
-
14. Granger CB, Hirsh J, Califf RM et al. Activated partial thromboplastin time and outcome after thrombolytic therapy for acute myocardial infarction. Circulation 1996; 93: 870-8.
-
(1996)
Circulation
, vol.93
, pp. 870-878
-
-
Granger, C.B.1
Hirsh, J.2
Califf, R.M.3
-
15
-
-
8544279582
-
A comparison of low-molecular-weight heparin with unfractionated heparin for unstable coronary artery disease
-
15. Cohen M, Demers C, Gurfinkel EP et al., for the Efficacy and Safety of Subcutaneous Enoxaparin in Non-Q Wave Coronary Events Study Group. A comparison of low-molecular-weight heparin with unfractionated heparin for unstable coronary artery disease. N Engl J Med 1997; 337: 447-52.
-
(1997)
N Engl J Med
, vol.337
, pp. 447-452
-
-
Cohen, M.1
Demers, C.2
Gurfinkel, E.P.3
-
16
-
-
0030789174
-
Comparison of low-molecular weight heparin with unfractionated heparin acutely and with placebo for 6 weeks in the management of unstable coronary disease
-
16. Klein W, Buchwald A, Hillis Se et al. Comparison of low-molecular weight heparin with unfractionated heparin acutely and with placebo for 6 weeks in the management of unstable coronary disease. Circulation 1997; 96: 61-8.
-
(1997)
Circulation
, vol.96
, pp. 61-68
-
-
Klein, W.1
Buchwald, A.2
Hillis, S.3
-
17
-
-
0024427768
-
Biochemistry and genetic engineering of hirudin
-
17. Johnson PH, Sze P, Winant R et al. Biochemistry and genetic engineering of hirudin. Semin Thromb Hemost 1989; 15: 302-15.
-
(1989)
Semin Thromb Hemost
, vol.15
, pp. 302-315
-
-
Johnson, P.H.1
Sze, P.2
Winant, R.3
-
18
-
-
0024344275
-
Studies on antithrombotic effects of recombinant hirudin
-
18. Markwardt F, Kaiser B, Nowak G. Studies on antithrombotic effects of recombinant hirudin. Thromb Res 1989; 89: 377-88.
-
(1989)
Thromb Res
, vol.89
, pp. 377-388
-
-
Markwardt, F.1
Kaiser, B.2
Nowak, G.3
-
19
-
-
0023874875
-
Pharmacokinetics and pharmacodynamics of hirudin in man after single subcutaneous and intravenous bolus administration
-
19. Bichler J, Fichtl B, Siebeck M, Fritz H. Pharmacokinetics and pharmacodynamics of hirudin in man after single subcutaneous and intravenous bolus administration. Drug Res 1988; 38: 704-10.
-
(1988)
Drug Res
, vol.38
, pp. 704-710
-
-
Bichler, J.1
Fichtl, B.2
Siebeck, M.3
Fritz, H.4
-
20
-
-
0025346345
-
Design and characterisation of hirulogs: A novel class of bivalent peptide inhibitors of thrombin
-
20. Maraganore JM, Bourdon P, Jablonski J, Ramachandran KL, Fenton JW. Design and characterisation of hirulogs: a novel class of bivalent peptide inhibitors of thrombin. Biochemistry 1990; 29: 7095-101.
-
(1990)
Biochemistry
, vol.29
, pp. 7095-7101
-
-
Maraganore, J.M.1
Bourdon, P.2
Jablonski, J.3
Ramachandran, K.L.4
Fenton, J.W.5
-
21
-
-
0027392867
-
Anticoagulant activity of Hirulog [tm], a direct thrombin inhibitor in humans
-
21. Fox I, Dawson A, Loynds P et al. Anticoagulant activity of Hirulog [tm], a direct thrombin inhibitor in humans. Thromb Hemost 1993; 69: 157-63.
-
(1993)
Thromb Hemost
, vol.69
, pp. 157-163
-
-
Fox, I.1
Dawson, A.2
Loynds, P.3
-
22
-
-
0027497137
-
Initial experience with a direct antithrombin, Hirulog in unstable angina - Anti-coagulant, antothrombotic and clinical effects
-
22. Lidon R, Theroux P, Juneau M, Adelman B, Maraganore J. Initial experience with a direct antithrombin, Hirulog in unstable angina - anti-coagulant, antothrombotic and clinical effects. Circulation 1993; 88: 1495-501.
-
(1993)
Circulation
, vol.88
, pp. 1495-1501
-
-
Lidon, R.1
Theroux, P.2
Juneau, M.3
Adelman, B.4
Maraganore, J.5
-
23
-
-
0028346249
-
Recombinant hirudin for unstable angina pectoris: A multicentre, randomized angiographic trial
-
23. Topol EJ, Fuster V, Harrington RA et al. Recombinant hirudin for unstable angina pectoris: a multicentre, randomized angiographic trial. Circulation 1994; 89: 1557-66.
-
(1994)
Circulation
, vol.89
, pp. 1557-1566
-
-
Topol, E.J.1
Fuster, V.2
Harrington, R.A.3
-
24
-
-
0030771823
-
Randomized, double-blind comparison Hirulog verses heparin in patients receiving streptokinase and aspirin for acute myocardial infarction (HERO)
-
24. White HD, Aylward PE, Frey MJ et al. Randomized, double-blind comparison Hirulog verses heparin in patients receiving streptokinase and aspirin for acute myocardial infarction (HERO). Circulation 1997; 96: 2155-61.
-
(1997)
Circulation
, vol.96
, pp. 2155-2161
-
-
White, H.D.1
Aylward, P.E.2
Frey, M.J.3
-
25
-
-
0028936602
-
Randomized double-blind comparison of hirulog with heparin as adjunctive therapy to streptokinase to promote early patency of the infarct related artery in acute myocardial infarction
-
25. Theroux P, Perez-Villa F, Waters D et al. Randomized double-blind comparison of hirulog with heparin as adjunctive therapy to streptokinase to promote early patency of the infarct related artery in acute myocardial infarction. Circulation 1995; 91: 2132-9.
-
(1995)
Circulation
, vol.91
, pp. 2132-2139
-
-
Theroux, P.1
Perez-Villa, F.2
Waters, D.3
-
26
-
-
0028326748
-
A pilot, early angiographic patency study using a direct thrombin inhibitor as adjunctive therapy to streptokinase in acute myocardial infarction
-
26. Lidon R, Theroux P, Lesperance J et al. A pilot, early angiographic patency study using a direct thrombin inhibitor as adjunctive therapy to streptokinase in acute myocardial infarction. Circulation 1994; 89: 1567-72.
-
(1994)
Circulation
, vol.89
, pp. 1567-1572
-
-
Lidon, R.1
Theroux, P.2
Lesperance, J.3
-
27
-
-
0028296374
-
A pilot trial of recombinant desulfatohirudin compared with heparin in conjunction with tissue-type plasminogen activator and aspirin for acute myocardial infarction: Results of the thrombolysis in myocardial infarction (TIMI) 5 trial
-
27. Cannon C, McCabe C, Henry T et al. A pilot trial of recombinant desulfatohirudin compared with heparin in conjunction with tissue-type plasminogen activator and aspirin for acute myocardial infarction: results of the thrombolysis in myocardial infarction (TIMI) 5 trial. J Am Coll Cardiol 1994; 23: 993-1003.
-
(1994)
J Am Coll Cardiol
, vol.23
, pp. 993-1003
-
-
Cannon, C.1
McCabe, C.2
Henry, T.3
-
28
-
-
0027209030
-
Use of a direct antithrombin, Hirulog, in place of heparin during coronary angioplasty
-
28. Toplo EJ, Bonan R, Jewitt D et al. Use of a direct antithrombin, Hirulog, in place of heparin during coronary angioplasty. Circulation 1993; 87: 1622-9.
-
(1993)
Circulation
, vol.87
, pp. 1622-1629
-
-
Toplo, E.J.1
Bonan, R.2
Jewitt, D.3
-
29
-
-
0029103184
-
Treatment with Bivalirudin (Hirulog) as compared with heparin during coronary angioplasty for unstable angina or post-infarction angina
-
29. Bittl JA, Strony J, Brinker JA et al. Treatment with Bivalirudin (Hirulog) as compared with heparin during coronary angioplasty for unstable angina or post-infarction angina. N Engl J Med 1995; 333: 764-9.
-
(1995)
N Engl J Med
, vol.333
, pp. 764-769
-
-
Bittl, J.A.1
Strony, J.2
Brinker, J.A.3
-
30
-
-
0028037517
-
Randomized trial of intravenous heparin versus recombinant hirudin for acute coronary syndromes
-
30. The Global Use of Strategies to Open Occluded Coronary Arteries (GUSTO) IIa Investigators. Randomized trial of intravenous heparin versus recombinant hirudin for acute coronary syndromes. Circulation 1994; 90: 1631-7.
-
(1994)
Circulation
, vol.90
, pp. 1631-1637
-
-
-
31
-
-
0028092111
-
Hirudin in acute myocardial infarction: Safety report from the Thrombolysis and Thrombin Inhibition in Myocardial Infarction (TIMI) 9A trial
-
31. Antman EM for the TIMI 9A Investigators. Hirudin in acute myocardial infarction: safety report from the Thrombolysis and Thrombin Inhibition in Myocardial Infarction (TIMI) 9A trial. Circulation 1994; 90: 1624-30.
-
(1994)
Circulation
, vol.90
, pp. 1624-1630
-
-
-
32
-
-
0028117846
-
Safety observations from the pilot phase of the randomized r-Hirudin for Improvement of Thrombolysis (HIT) III study
-
32. Neuhaus K-L, v. Essen R, Tebbe U et al. Safety observations from the pilot phase of the randomized r-Hirudin for Improvement of Thrombolysis (HIT) III study. Circulation 1994; 90: 1638-42.
-
(1994)
Circulation
, vol.90
, pp. 1638-1642
-
-
Neuhaus, K.-L.1
Essen, R.V.2
Tebbe, U.3
-
33
-
-
0029835392
-
A comparison of recombinant hirudin with heparin for the treatment of acute coronary syndromes
-
33. The Global Use of Strategies to Open Occluded Coronary Arteries (GUSTO) IIb Investigators. A comparison of recombinant hirudin with heparin for the treatment of acute coronary syndromes. N Engl J Med 1996; 335: 775-82.
-
(1996)
N Engl J Med
, vol.335
, pp. 775-782
-
-
-
34
-
-
0029788104
-
Hirudin in acute myocardial infarction: Thrombolysis and Thrombin Inhibition in Myocardial Infarction (TIMI) 9B trial
-
34. Antman EM for the TIMI 9A Investigators. Hirudin in acute myocardial infarction: thrombolysis and Thrombin Inhibition in Myocardial Infarction (TIMI) 9B trial. Circulation 1996; 94: 911-21.
-
(1996)
Circulation
, vol.94
, pp. 911-921
-
-
-
35
-
-
0028952989
-
Activated clotting time as an appropriate test to compare heparin and direct thrombin inhibitors such as hirudin or Ro 46-6240 in experimental arterial thrombosis
-
35. Carteaux JP, Gast A, Tschopp TB, Roux S. Activated clotting time as an appropriate test to compare heparin and direct thrombin inhibitors such as hirudin or Ro 46-6240 in experimental arterial thrombosis. Circulation 1995; 91: 1568-74.
-
(1995)
Circulation
, vol.91
, pp. 1568-1574
-
-
Carteaux, J.P.1
Gast, A.2
Tschopp, T.B.3
Roux, S.4
-
36
-
-
0030844045
-
Direct thrombin inhibition superior to heparin during and after thrombolysis: Dose, duration and drug
-
36. Chesebro JH. Direct thrombin inhibition superior to heparin during and after thrombolysis: dose, duration and drug. Circulation 1997; 96: 2118-20.
-
(1997)
Circulation
, vol.96
, pp. 2118-2120
-
-
Chesebro, J.H.1
|