Associations of MHC class II alleles with insulin-dependent diabetes mellitus (IDDM) in patients from North India

Human Immunology

Volumn 60, Issue 6, 1999, Pages 524-531

  Rani, Rajni ^a,b   Sood, Ajay ^c   Lazaro, Ana M ^a   Stastny, Peter ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b NATIONAL INSTITUTE OF IMMUNOLOGY   (India)

^c ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

IDDM; Polymerase chain reaction (PCR); Sequence specific oligonucleotide probes (SSOP)

Indexed keywords

MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; HETEROZYGOSITY; HLA SYSTEM; HOMOZYGOSITY; HUMAN; IMMUNOGENETICS; INDIA; INSULIN DEPENDENT DIABETES MELLITUS; MAJOR HISTOCOMPATIBILITY COMPLEX; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

ADULT; ALLELES; DIABETES MELLITUS, TYPE 1; GENE FREQUENCY; GENES, MHC CLASS II; HETEROZYGOTE; HLA-DP ANTIGENS; HLA-DQ ANTIGENS; HLA-DR ANTIGENS; HLA-DR3 ANTIGEN; HLA-DR4 ANTIGEN; HOMOZYGOTE; HUMANS; INDIA;

EID: 0033024150     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0198-8859(99)00032-4     Document Type: Article

References (58)

1. Svejgaard A., Platz P., Ryder L.P. Joint Report insulin dependent diabetes mellitus . Terasaki P. Histocompatibility testing 1980. 1980;638 UCLA Tissue Typing Laboratory, Los Angeles.
2. Fernandez-Vina M.A., Ramirez L.C., Raskin P., Stastny P. Genes for insulin-dependent diabetes mellitus (IDDM) in the major histocompatibility complex (MHC) of African Americans. Tissue Antigens. 41:1993;57.
3. Krokowski M., Bodalski J., Bratek A., Boitard C., Caillat-Zucman S. HLA class II associated predisposition to insulin-dependent diabetes mellitus in a Polish population. Hum Immunol. 59:1998;451.
4. Ottenhoff T.H., Mengistu M., Tadesse G., DeVries R.R. HLA-DR and DQ antigens in insulin dependent diabetes in Ethiopia. Tissue Antigens. 30:1987;193.
5. Omar M.A., Hammond M.G., Asmal A.C. HLA-A, B, C and DR antigens in young South African blacks with type I (insulin-dependent) diabetes mellitus. Diabetologia. 26:1984;20.
6. Vadheim C.M., Zeidler A., Rotter J.I., Langbaum M., Shulman L.A., Spencer M.R., Costin G., Riley W.J., Maclaren N.K. Different HLA haplotypes in Mexican Americans with IDDM. Diabetes Care. 12:1989;497.
7. Ayed K., Bardi R., Gorgi Y., Janhani F. HLA A, B and DR antigens and complotype in Tunisian patients with diabetes mellitus. Dis Markers. 7:1989;43.
8. Ozsahin H., Haktan M., Ozbakir F., Aydin A., Yazici H. The type 1 diabetes and HLA-DR in Turkey. Diabete Metab. 17:1991;421.
9. Cambon-de Mouzon A., Ohayon E., Hauptmann G., Sevin A., Abbal M., Sommer E., Vergnes H., Ducos J. HLA-A, B, C, DR antigens, Bf, C4 and Glyoxalase (GLO) polymorphisms in French Basques with Insulin dependent diabetes mellitus (IDDM). Tissue Antigens. 19:(5):1982;366.
10. Svejgaard A., Jakobsen B.K., Platz P., Ryder L.P., Nerup J., Christy M., Borch-Johnsen K., Parving H.H., Deckert T. HLA associations in insulin-dependent diabetes search for heterogeneity in different groups of patients from a homogeneous population . Tissue Antigens. 28:1986;237.
11. Boehm B.O., Schifferdecker E., Rosak C., Kuehnl P., Driesel A.J., Schoffling K. HLA-DR4 associated DQw8 allele is confined to HLA-DR3/4 heterozygous type I (insulin-dependent) diabetics. Tissue Antigens. 36:(2):1990;81.
12. Thomson G., Robinson W.P., Kuhner M.K., Joe S., Klitz W. HLA and insulin gene associations with IDDM. Genet Epidemiol. 6:(1):1989;155.
13. Wolf E., Spencer K.M., Cudworth A.G. The genetic susceptibility to type I (insulin-dependent) diabetes analysis of the HLA-DR association . Diabetologia. 24:1983;224.
14. Chan S.H., Yeo P.P., Lee B.W., Tan S.H., Cheah J.S., Wong H.B. HLA and insulin dependent diabetes mellitus in Sigaporean Chinese. Ann Acad Med Singapore. 14:(2):1985;215.
15. Hawkins B.R., Lam K.S., Ma J.T., Low L.C., Cheung P.T., Serjeantson S.W., Yeung R.T. Strong association of HLA-DR3/DRw9 heterozygosity with early onset insulin-dependent diabetes mellitus in Chinese. Diabetes. 36:(11):1987;1297.
16. Huang H.S., Peng J.T., She J.Y., Zhang L.P., Caho C.C., Lui K.H., She J.X. HLA-encoded susceptibility to insulin-dependent diabetes mellitus is determined by DR and DQ genes as well as their linkage disequilibrium in a Chinese population. Hum Immunol. 44:(4):1995;210.
17. Chuang L.M., Wu H.P., Tsai W.Y., Lin B.J., Tai T.Y. Transcomplementation of HLA DQA1-DQB1 in DR3/DR4 and DR3/9 heterozygotes and IDDM in Taiwanese families. Diabetes Care. 18:(11):1995;1483.
18. Penny M.A., Jenkins D., Mijovic C.H., Jacobs K.H., Cavan D.A., Yeung V.T., Cockram C.S., Hawkins B.R., Fletcher J.A., Barnett A.H. Susceptibility to IDDM in a Chinese populaiton. Role of HLA class II alleles. Diabetes. 41:(8):1992;914.
19. Hu C.Y., Allen M., Chuang L.M., Lin B.J., Gyllensten U. Association of insulin-dependent diabetes mellitus in Taiwan with HLA class II DQB1 and DRB1 alleles. Hum Immunol. 38:1993;105.
20. Kockum I., Wassmuth R., Holmberg E., Michelsen B., Lernmark A. HLA-DQ primarily confers protection and HLA-DR susceptibility in type 1 (insulin-dependent) diabetes studied in population based affected families and controls. Am J Hum Genet. 53:1993;150.
21. Tait B.D., Mraz C., Harrison L.C. Association of HLA-DQw3 (TA10-) with type I diabetes occurs with DR3/4 but not DR1/4 patients. Diabetes. 37:1988;926.
22. Nepom G.T., Erlich H.A. MHC class II molecules and autoimmunity. Annu Rev Immunol. 9:1991;493.
23. Ronningen K.S., Spurkland A., Iwe T., Vartdal F., Thorsby E. Distribution of HLA-DRB1, DQA1 and DQB1 alleles and DQA1-DQB1 genotypes among Norweigian patients with insulin-dependent diabetes mellitus. Tissue Antigens. 37:1991;105.
24. Thorsby E., Roningen K.S. Particular HLA-DQ molecules play a dominant role in determining susceptibility or resistance to type I (insulin dependent) diabetes mellitus. Diabetologia. 36:1993;371.
25. Nepom B.S., Schwarz D., Palmer J.P. Transcomplementation of HLA genes in IDDM, HLA-DQ alpha and beta chains produce hybrid molecules in DR3/4 heterozygotes. Diabetes. 36:1987;114.
26. Sanjeevi C.B., Landin-Olsson M., Kockum I., Dahlquist G., Lernmark A. Effects of the second HLA-DQ haplotypes on association with childhood insulin-dependent diabetes mellitus. Tissue Antigens. 45:1995;148.
27. Van der Auwera B., Van Waeyenberge C., Schuit F., Heimberg H., Vandewalle L., Gorus F., Flament J. DRB1*0403 protects against IDDM in Caucasians with high risk heterozygous DQA1*0301-DQB1*0302/DQA1*0501-DQB1*0201 genotype. Belgian Diabetes Registry. Diabetes. 44:1995;527.
28. Cucca F., Lampis R., Macis D., Angius E., Masile P., Chessa M. The distribution of DR4 haplotypes in Sardinia suggests a primary association of type I diabetes with DRB1 and DQB1 loci. Hum Immunol. 43:1995;301.
29. Tait B.D., Drummond B.P., Varney M.D., Harrison L.C. HLA-DRB1*0401 is associated with susceptibility to insulin-dependent diabetes mellitus independently of the DQB1 locus. Eur J Immunogenet. 22:1995;289.
30. Erlich H.A., Rotter J.I., Chang J.D., Shaw S.J., Raffel L.J., Klitz W., Bugawan T.L., Zeidler A. Association of HLA-DPB1*0301 with IDDM in Mexican Americans. Diabetes. 45:1996;610.
31. Balducci-Silano P.L., Layrisse Z.E. HLA-DP and susceptibility to insulin-dependent diabetes mellitus in an ethnically mixed population. Associations with other HLA alleles. J Autoimmun. 8:1995;425.
32. Todd J.A., Bell J.I., McDevitt H.O. HLA DQ beta gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus. Nature. 329:1987;599.
33. Badenhoop K., Walfish P.G., Rau H., Fischer S., Nicolay A., Bogner U., Schleusener H., Usadel K.H. Susceptibility and resistance alleles of human leukocyte antigen (HLA) DQA1 and DQB1 are shared in endocrine autoimmune disease. J Clin Endocrinol Metabol. 80:(7):1995;212.
34. Chauffert M., Cisse A., Cheveene D., Parfait B., Michel S., Trivin F. HLA-DQ beta 1 typing and non Asp57 alleles in the aborigine population of Senegal. Diabetes Care. 18:1995;677.
35. Erlich H.A., Zeidler A., Chang J., Shaw S., Raffel L.J., Klitz W., Beshkov Y., Costin G., Pressman S., Bugawan T., Rolter J.I. HLA class II alleles and susceptibility to insulin dependent diabetes mellitus in Mexican American families. Nat Genet. 3:1993;358.
36. Pugliese A., Gianani R., Moromisato R., Awdeh Z.L., Alper C.A., Erlich H.A. HLA-DQB1*0602 is associated with dominant protection from diabetes even among islet cell antibody-positive first degree relatives of patients with IDDM. Diabetes. 44:1995;608.
37. Baisch J.M., Weeks T., Giles R., Hoover M., Stastny P. Analysis of DQ genotypes and susceptibility in insulin dependent-diabetes mellitus. N Eng J Med. 322:1984;1836.
38. Omar M.H., Hammond M.G., Rajput M.C., Asmal A.C. HLA A, B, C and DR antigens in young south African Indians with insulin-dependent diabetes mellitus. S Afr Med J. 66:1984;765.
39. Fletcher J., Odugbesan O., Mijovic C., Mackay E., Bradwell A.R., Barnett A.H. Class II HLA-DNA polymorphisms in type I (insulin-dependent) diabetic patients of North Indian origin. Diabetologia. 31:(6):1988;343.
40. Jenkins D., Fletcher J., Penny M.A., Mijovic C.H., Jacobs K.H., Bradwell A.R., Barnett A.H. DRB genotyping supports recessive inheritance of DR3-associated susceptibility to insulin-dependent diabetes mellitus. Am J Hum Genet. 49:1991;49.
41. Bhatia E., Mehra N.K., Taneja V., Vaidya M.C., Ahuja M.M. HLA-DR antigen frequencies in a North Indian type I diabetic population. Diabetes. 34:1985;565.
42. Fernandez-Vina M.A., Gao X., Morases M.E., Moraes J.R., Salatiel I., Miller S., Tsai S., Sun Y., An J., Layrisse Z., Gazit E., Brautbar C., Stastny P. Alleles at four class II loci determined by oligonucleotide hybridization and their associations in five ethnic groups. Immunogenetics. 34:1991;299.
43. Fernandez-Vina M.A., Moraes M.E., Stastny P. DNA typing for class II HLA antigens with allele-specific or group-specific amplification III. Typing for 24 alleles of HLA-DP. Hum Immunol. 38:1991;24.
44. Rani R., Fernandez-Vina M.A., Zhang S., Stastny P. HLA-DPB1 alleles in a population from North India and description of a new variant (DPB1*5601). Tissue Antigen. 45:1995;264.
45. Rani R., Fernandez-Vina M.A., Stastny P. Associations between HLA class II alleles in a North Indian population. Tissue Antigens. 52:1998;37.
46. Rani R., Mukherjee R., Stastny P. Diversity of HLA-DR2 in North Indians the changed scenario after the discovery of DRB1*1506 . Tissue Antigens. 52:1998;147.
47. Tiwari J.L., Terasaki P.I. HLA and disease associations. 1985;Springer Verlag, New York.
48. Gupta M.M., Raghunath D., Kher S.K., Radhakrishnan A.P. Human leokocyte antigen and insulin dependent diabetes mellitus. J Assoc Physicians India. 39:1991;540.
49. Caillat-Zucman, Djilali-Saiah I, Timsit J, Bonifacio E, Sepe V, Collins P, Bottazzo GF, Maclaren N, Delamaire M, Martin S, Yamamoto AM, McWeeney S, Valdes AM, Babron MC, Thorsby E, Clerget-Darpoux F, Thomson G, Bach JF: Insulin dependent diabetes mellitus (IDDM): 12th International Histocompatibility Workshop study. In Charron D, (ed.): HLA Genetic diversity of HLA functional and Medical Implication, (Vol. 1). Paris, EDK Medical and Scientific International Publisher, 1997.
50. Lee B.W., Tan S.H., Wong H.B., Chan S.H., Wee G.B., Tan C.L., Tan K.W. HLA-DR antigens in Chinese children with insulin dependent diabetes mellitus. Ann Acad Med Singapore. 14:(2):1985;219.
51. Esteal S., Viswanathan M., Serjeantson S.W. HLA-DP, -DQ and in RFLP types in South Indian insulin-dependent diabetes mellitus patients. Tissue Antigens. 35:1990;71.
52. Hitman G.A., Mohan V. The genetic susceptibility to IDDM in British and South Indian subjects. Biomed Biochim Acta. 47:(4-5):1988;329.
53. Subramanian V.S., Krshnaswami C.V., Damodaran C. HLA, ESD, GLO1, C3 and HP polymorphism and juvenile insulin dependent diabetes mellitus in Tamil Nadu (South India). Diabetes Res Clin Pract. 25:1994;51.
54. Morel P.A., Dorman J.S., Todd J.A., McDevitt H.O., Trucco M. Aspartic acid at position 57 of the HLA-DQ beta chain protects against type I diabetes a family study . Proc Natl Acad Sci USA. 85:1988;8111.
55. Mogzoub M.M., Stephens H.A., Sachs J.A., Biro P.A., Cutbush S., Wu Z., Bottazzo G.F. HLA-DP polymorphism in Sudanese controls and patients with insulin dependent diabetes mellitus. Tissue Antigens. 40:(2):1992;64.
56. Lie B.A., Akselsen H.E., Jones G., Dahl-Jorgensen K., Ronningen K.S., Thorsby E., Undlien D.E. HLA associations in insulin-dependent diabetes mellitus no independent association to particular DP genes . Hum Immunol. 55:(2):1997;170.
57. Horwitz M.C., Bradley L.M., Harbertson J. Diabetes induced by Coxsackie virus initiation by bystander damage and not molecular mimicry . Nature Med. 4:1998;781.
58. Singh B., Prange S., Jevnikar A.M. Protective and destructive effects of microbial infection in insulin-dependent diabetes mellitus. Sem Immunol. 10:(1):1998;79.