Immunotherapy in children with allergic asthma: Effect on bronchial hyperreactivity and pharmacotherapy

Journal of Allergy and Clinical Immunology

Volumn 103, Issue 4, 1999, Pages 609-614

  Hedlin, Gunilla ^a   Wille, Sören ^c   Browaldh, Lars ^c   Hildebrand, Hans ^c   Holmgren, Daniel ^c   Lindfors, Anders ^c   Nordvall, S Lennart ^c   Lowenstein, Henning ^b  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b ALK ABELLÓ   (Denmark)

^c Karolinska Institutet ^*

Author keywords

Asthma; Bronchial hyperreactivity; Budesonide; Cat, dust mite, and pollen allergy; Children; Immunotherapy

Indexed keywords

ALLERGEN; BUDESONIDE; CORTICOSTEROID; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G4; PLACEBO;

ADOLESCENT; ALLERGIC ASTHMA; ANTIBODY BLOOD LEVEL; ARTICLE; BRONCHUS HYPERREACTIVITY; CAT; CLINICAL ARTICLE; CLINICAL TRIAL; DRUG TOLERANCE; DUST; HUMAN; IMMUNOTHERAPY; MITE; PEAK EXPIRATORY FLOW; POLLEN ALLERGY; PRIORITY JOURNAL; RECURRENT DISEASE; SCHOOL CHILD; SKIN TEST; STATISTICAL ANALYSIS; SYMPTOMATOLOGY; TREATMENT PLANNING;

EID: 0033022568     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-6749(99)70232-0     Document Type: Article

References (13)

1. 1. Croner S. Kjellman N-IM. Natural history of bronchial asthma in childhood: a prospective study from birth up to 12-14 years of age. Allergy 1992;47:150-7.
2. 2. Wood RA, Mudd K, Eggleston PA. The distribution of cat and dust mile allergens on wall surfaces. J Allergy Clin Immunol 1992;89:126-30.
3. 3. Hedlin G, Graff-Lonnevig V, Heilborn H, et al. Immunotherapy with cat and dog dander extracts V: effects of 3 years of treatment. J Allergy Clin Immunol 1991;87:955-64.
4. 4. Doull IJ, Freezer NJ, Holgate ST. Growth of prepubertal children with mild asthma treated with inhaled beclomethasone dipropionate. Am J Respir Crit Care Med 1995;151:1715-9.
5. 5. Cockcroft DW, Killian DN, Mellon JJA, Hargreave FE. Bronchial reactivity to inhaled histamine: a method and clinical survey. Clin Allergy 1977;7:235-43.
6. 6. Lynch MJ. Extended standard curve stability on the CCD Magic Lite immunoassay system using a two-point adjustment. J Biolumin Chemilumin 1989;4:615-9.
7. 7. Jacobsen L, Johansen N, Rohde H, Lynch M, Comerci C, Tugendhaft N. Evaluation of the Magic Lite SQ specific IgE assay system [abstract]. Clin Chemistry 1990;36:1189.
8. 8. Rak S, Lowhagen O, Venge P. The effect of immunotherapy on bronchial hyperresponsiveness and eosinophil cationic protein in pollen allergic patients. J Allergy Clin Immunol 1988;82:470-80.
9. 9. Van Essen-Zandvliet EE, Hughes MD, Waalkens HJ, Duiverman EJ, Pocock SJ, Kerrebijn KF. Effects of 22 months of treatment with inhaled corticosteroids and/or beta-2 agonists on lung function, airway responsiveness and symptoms in children with asthma. Am Rev Respir Dis 1992;146:547-54.
10. 10. de Baets FM, Goetyn M, Kerrebijn KF. The effect of two months of treatment with inhaled budesonide on bronchial responsiveness to histamine and house-dust mite antigen in asthmatic children. Am Rev Respir Dis 1990;142:581-6.
11. 11. Munir AKM, Einarsson R, Schou C, Dreborg SKG. Allergens in school dust: I. The amount of major cat (Fel d I) and dog (Can f I) allergen in dust from Swedish schools is high enough to probably cause perennial symptoms in most children with asthma who are sensitised to cat and dog. J Allergy Clin Immunol 1993;91:1067-74.
12. 12. Ihre E, Zetterström O. Increase in non-specific bronchial hyperresponsiveness after repeated inhalation of low doses of allergen. Clin Exp Allergy 1993;23:298-305.
13. 13. Adkinson F, Eggleston P, Eney D, et al. A controlled trial of immunotherapy for asthma in allergic children. N Engl J Med 1997;336:324-31.