Retrospective analysis of effect of low-dose aprotinin priming on allogeneic blood transfusion in repeated cardiac operations

Perfusion

Volumn 14, Issue 3, 1999, Pages 189-194

  Miyashita, Tetsuya ^a   Hayashi, Yukio ^a   Ohnishi, Yoshihiko ^a   Kuro, Masakazu ^a  

^a NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

APROTININ;

ADULT; AGED; ARTICLE; BLEEDING; BLOOD TRANSFUSION; CONTROLLED STUDY; DRUG EFFICACY; ELECTIVE SURGERY; FEMALE; HEART SURGERY; HUMAN; INTENSIVE CARE; INTRAVENOUS DRUG ADMINISTRATION; MAJOR CLINICAL STUDY; MALE; MEDIASTINUM; PRIORITY JOURNAL; REOPERATION; RETROSPECTIVE STUDY; RISK FACTOR;

EID: 0033021694     PISSN: 02676591     EISSN: None     Source Type: Journal    
DOI: 10.1177/026765919901400306     Document Type: Article

References (21)

1. Ray MJ, Marsh NA, Hawson GAT. Relationship of fibrinolysis and platelet function to bleeding after cardiopulmonary bypass. Blood Coagul Fibrinolysis 1994; 5: 679-85.
2. Lu H, Buit CD, Soria J et al. Postoperative hemostasis and fibrinolysis in patients undergoing cardiopulmonary bypass with or without aprotinin therapy. Thoromb Haemost 1994; 72: 438-43.
3. Khuri SF, Valeri CR, Loscalzo J et al. Heparin causes platelet dysfunction and induces fibrinolysis before cardiopulmonary bypass. Ann Thorac Surg 1995; 60: 1008-14.
4. Horrow JC. Management of coagulopathy associated with cardiopulmonary bypass. In: Gravlee GP, Davis RF, Utley JR eds. Cardiopulmonary bypass; principles and practice. Baltimore, MD: Williams & Wilkins, 1993: 436-66.
5. Blauhut B, Gross C, Necek S et al. Effects of high-dose aprotinin on blood loss, platelet function, fibrinolysis, complement and renal function after cardiopulmonary bypass. J Thorac Cardiovasc Surg 1991; 101: 958-67.
6. van Oeveren W, Hander MP, Roozendaal KJ et al. Aprotinin protects platelets against the initial effect of cardiopulmonary bypass. J Thorac Cardiovasc Surg 1990; 99: 788-97.
7. Lu H, Soria C, Commin P et al. Hemostasis in patients undergoing extracorporeal circulation: the effect of aprotinin (Trasylol). Thromb Haemost 1991; 66: 633-37.
8. Royston D, Bidstrup BP, Taylor KM, Sapsford RN. Effect of aprotinin on need for blood transfusion after repeat open-heart surgery. Lancet 1987; 2: 1289-91.
9. Davis R, Whittington R. Aprotinin. Drugs 1995; 49: 954-83.
10. Menichetti A, Tritapepe L, Ruvolo G et al. Changes in coaglation patterns, blood loss and blood use after cardiopulmonary bypass: aprotinin vs tranexamic acid vs epsilon aminocaproic acid. J Cardiovasc Surg 1996; 37: 401-407.
11. Ashraf S, Tian Y, Cowan D et al. 'Low-dose' aprotinin modifies haemostasis but not proinflammatory cytokine release. Ann Thorac Surg 1997; 63: 68-73.
12. D'Errico CC, Shayevitz JR, Martindale SJ et al. The efficacy and cost of aprotinin in children undergoing reoperative open-heart surgery. Anesth Analg 1996; 83: 1193-99.
13. Vandenvelde C, Fondu P, Dubois-Primo J. Low-dose aprotinin for reduction of blood loss after cardiopulmonary bypass. Lancet 1991; 337: 1157-58.
14. Ray MJ, Marsh NA, Just SJE et al. Pre-operative platelet dysfunction increases the benefit of aprotinin in cardiopulmonary bypass. Ann Thorac Surg 1997; 63: 57-63.
15. Campbell FW, Edmunds LH. Platelet function and cardiopulmonary bypass. In: Gravlee GP, Davis RF, Utley JR eds. Cardiopulmonary bypass; principles and practice. Baltimore, MD: Williams & Wilkins, 1993: 407-35.
16. Scheule AM, Jurmann MJ, Wendel HP et al. Anaphylactic shock after aprotinin re-exposure: time course of aprotinin-specific antibodies. Ann Thorac Surg 1997; 63: 242-44.
17. Dietrich W, Späth P, Ebell A, Richter JA. Prevalence of anaphylactic reactions to aprotinin: analysis of 248 re-exposures to aprotinin in heart operations. J Thorac Cardiovasc Surg 1997; 113: 194-201.
18. Cosgrove DM III, Heric B, Lytle BW et al. Aprotinin therapy for reoperative myocardial revascularization: a placebo-controlled study. Ann Thorac Surg 1992; 54: 1031-38.
19. Green D, Sanders J, Eiken M et al. Recombinant aprotinin in coronary artery bypass graft operations. J Thorac Cardiovasc Surg 1995; 110: 963-70.
20. Bailey CR, Wielogorski AK. Randomized placebo-controlled double-blind study of two low-dose aprotinin regimens in cardiac surgery. Br Heart J 1994; 71: 349-53.
21. Matzdorff AC, Green D, Cohen I, Bauer KD. Effect of recombinant aprotinin on platelet activation in patients undergoing open-heart surgery. Hemostasis 1993; 23: 293-300.