Etiology of the inflammatory bowel diseases

International Journal of Colorectal Disease

Volumn 14, Issue 1, 1999, Pages 2-9

  Hugot, J P ^b   Zouali, H ^a   Lesage, S ^a   Thomas, G ^a,c  

^a INSERM   (France)

^b HÔPITAL ROBERT DEBRÉ   (France)

^c HÔPITAL SAINT ANTOINE   (France)

Author keywords

Crohn's disease; Epidemiology; Genetics; Inflammatory bowel disease; Ulcerative colitis

Indexed keywords

ARTICLE; CHROMOSOME 12; CIGARETTE SMOKING; CROHN DISEASE; ENTERITIS; ENVIRONMENTAL FACTOR; FAMILY HISTORY; GENE LOCUS; GENETIC PREDISPOSITION; HUMAN; PRIORITY JOURNAL; RISK FACTOR; TOBACCO; ULCERATIVE COLITIS;

CHROMOSOMES, HUMAN, PAIR 12; CHROMOSOMES, HUMAN, PAIR 16; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INCIDENCE; INFLAMMATORY BOWEL DISEASES; LIFE STYLE; RISK FACTORS; SMOKING;

EID: 0033021409     PISSN: 01791958     EISSN: None     Source Type: Journal    
DOI: 10.1007/s003840050175     Document Type: Article

References (52)

1. Tysk C, Lindberg E, Järnerot G, Flodérus-Myrhed B (1988) Ulcerative colitis and Crohn's disease in an unselected population of monozygotic and dizygotic twins. A study of heritability and the influence of smoking. Gut 29:990-996
2. Thompson NP, Driscoll R, Pounder RE, Wakefield AJ (1996) Genetics vs environment in inflammatory bowel disease: results of a British twin study. BMJ 312:95-96
3. Orholm M, Binder V, Sorensen TIA, Kyvik KO (1996) Inflammatory bowel disease in a Danish twin register. Gut 39 [Suppl 3]:A187
4. Shivananda S, Lennard-Jones J, Logan R, et al (1996) Incidence of inflammatory bowel disease across Europe: is there a difference between north and south? Results of the European collaborative study on inflammatory bowel disease (EC-IBD). Gut 39:690-697
5. Tobin MV, Logan RFA, Langman MJS, McConnell RB, Gilmore IT (1987) Cigarette smoking and inflammatory bowel disease. Gastroenterology 93:316-321
6. Cosnes J, Carbonnel F, Beaugerie L, Le Quintrec Y, Gendre JP (1996) Effects of cigarette smoking on the long-term course of Crohn disease Gastroenterology 110:424-431
7. Merrett MN, Mortensen N, Kettlewell M, Jewell DO (1996) Smoking may prevent pouchitis in patients with restorative proctocolectomy for ulcerative colitis. Gut 38:362-364
8. Pullan RD, Rhodes J, Ganesh S, et al (1994) Transdermal nicotine for active ulcerative colitis. N Engl J Med 330:811-815
9. Sanderson JD, Moss MT, Tizard MLV, Hermon-Taylor J (1992) Mycobacterium paratuberculosis DNA in Crohn's disease tissue. Gut 33:890-896
10. Thompson NP, Montgomery SM, Pounder RE, Wakefield AJ (1995) Is measles vaccination a risk factor for inflammatory bowel disease? Lancet 345:1071-1074
11. Ekbom A, Daszak P, Kraaz W, Wakefield AJ (1996) Crohn's disease after in-utero measles virus exposure. Lancet 348:515-517
12. Levin J, Dhillon AP, Sim R, Mazure G, Pounder RE, Wakefield AJ (1995) Persistent measles virus infection of the intestine: confirmation by immunogold electron mivroscopy. Gut 36:564-569
13. Haga Y, Funakoshi O, Kuroe K, et al (1996) Absence of measles viral genomic sequence in intestinal tissues from Crohn's disease by nested polymerase chain reaction. Gut 38:211-215
14. Satsangi J, Welsh KI, Bunce M, Julier C, Farrant JM, Bell JI, Jewell DP (1996) Contribution of the genes of the major histocompatibility complex to susceptibility and disease phenotype in inflammatory bowel disease. Lancet 347: 1212-1217
15. Naom I, Lee J, Ford D, Bowman SJ, Lanchbury JS, Haris I, Hodgson SV, Easton D, Lennard-Jones J, Mathew C (1996) Analysis of the contribution of HLA genes to genetic predisposition in inflammatory bowel disease. Am J Hum Genet 59:226-233
16. Hugot JP, Laurent-Puig P, Gower-Rousseau C, Caillat-Zueman C, Beaugerie L, Dupas JL, Van Gossum A, Bonaiti-Pellie C, Cortot A, Thomas G, the GETAID (1994) Linkage analyses of chromosome 6 loci, including HLA, in familial aggregations of Crohn's disease. Am J Med Genet 52:207-213
17. Futami S, Aoyama N, Honsako Y, et al (1995) HLA-DRB 1*1502 allele, subtype of DR15, is associated with susceptibility to ulcerative colitis and its progression. Dig Dis Sci 40:814-818
18. Toyoda H, Wang SJ, Yang HY, et al (1993) Distinct associations of HLA class II genes with inflammatory bowel disease. Gastroenterology 104:741-748
19. Danzé PM, Colombel JF, Jacquot S, et al (1996) Association of HLA class II genes with susceptibility to Crohn's disease. Gut 38:69-72
20. Reinshagen M, Loeliger C, Kuehnl P, et al (1996) HLA class II gene frequencies in Crohn's disease: a population based analysis in Germany. Gut 38:538-542
21. Bouma G, Poen AC, Garcia-Gonzalez MA, et al (1998) HLA-DRB 1*03, but not the TNFα-308 promoter gene polymorphism confers protection against fistulising Crohn's disease. Immunogenetics 47:451-455
22. Heresbach D, Colombel JF, Danzé PM, Semana G (1996) The HLADRB 1*03016DQB 1*0201 haplotype confers protection against inflammatory bowel disease. Am J Gastroenterol 5:1060
23. Plevy SE, Targan SR, Yang H, Fernandez D, Rotter JI, Toyoda H (1996) Tumor necrosis factor microsatellites define a Crohn's disease - associated haplotype on chromosome 6. Gastroenterology 110:1053-1060
24. Bouma G, Xia B, Crusius JBA, et al (1996) Distribution of four polymorphims in the tumour necrosis factor (TNF) genes in patients with inflammatory bowel disease (IBD). Clin Exp Immunol 103:391-396
25. Louis E, Satsangi J, Rousosmoustakaki M, et al (1996) Cytokine gene polymorphisms in inflammatory bowel disease. Gut 39:705-710
26. Heresbach D, Ababou A, Bourienne A, et al (1997) Etude du polymorphisme des microsatellites et des gènes du tumor necrosis factor (TNF) au cours des maladies inflammatoires chroniques de l'intestin. Gastroenterol Clin Biol 21:555-61
27. Mansfield JC, Holden H, Tarlow JK, et al (1994) Novel genetic association between ulcerative colitis and the anti-inflammatory cytokine interleukin-1 receptor antagonist. Gastroenterology 106:637-642
28. Andus T, Daig R, Vogl D, et al (1997) Imbalance of the interleukin 1 system in colonic mucosa-association with intestinal inflammation and interleukin 1 receptor agonist genotype 2. Gut 41:651-657
29. Duerr RH, Tran T (1995) Association between ulcerative colitis and a polymorphism intron 2 of the interleukin-1 receptor antagonist. Gastroenterology 108:A812
30. Tountas NA, Yang H, Coulter DI, Rotter JI (1996) Increased carriage of allele 2 of IL-1 receptor antagonist (IL-1ra) in Jewish populations: the strongest known genetic association in ulcerative colitis. Gastroenterology 110: A1029
31. Bioque G, Crusius JBA, Koutroubakis I, et al (1995) Allelic polymorphism in IL-1β and IL-1receptor antagonist (IL-1Ra) genes in inflammatory bowel disease. Clin Exp Immunol 102:379-383
32. Heresbach D, Alizadeh M, Dabadie A, et al (1997) Significance of interleukin-1β and interleukin-1 receptor antagonist genetic polymorphism in inflammatory bowel diseases. Am J Gastroenterol 92:1164-1169
33. Spielman RS, Ewens WJ (1996) The TDT and other family based tests for linkage disequilibrium and association. Am J Hum Genet 59:983-989
34. Jorde LB (1995) Linkage disequilibrium as a gene mapping tool. Am J Hum Genet 56:11-14
35. Hugot JP, Laurent-Puig P, Gower-Rousseau C, Olson JM, Lee JC, Beaugerie L, Naom I, Dupas JL, Van Gossum JL, GETAID, Orholm M, Bonaiti-Pellie M, Weissenbach J, Mathew C, Lennard-Jones JE, Cortot A, Colombel JF, Thomas G (1996) Mapping of a susceptibility locus for Crohn's disease on chromosome 16. Nature 379:821-823
36. Satsangi J, Parkes M, Louis E, Hashimoto L, Kato N, Welsh K, Terwilliger JD, Lathrop GM, Bell JI, Jewell DP (1996) Two stage genome wide search in inflammatory bowel disease provides evidence for susceptibility loci on chromosome 3:7 and 12. Nat Genet 14:199-202
37. Cho JH, Nicolae DL, Gold LH, Fields CT, LaBuda MC, Rohal PM, Pickles MR, Qin L, Fu Y, Mann JS, Kirschner BS, Jabs EW, Weber J, Hanauer SB, Bayless TM, Brant SR (1998) Identification of novel susceptibility loci for inflammatory bowel disease on chromosomes 1p, 3q, and 4q: evidence for epistasis between 1p and IBD1. Proc Natl Acad Sci USA 95:7502-7507
38. Ohmen JD, Yang HY, Yamamoto KK, Zhao HY, Ma Y, Bentley LG, Huang Z, Gerwehr S, Pressman S, McElree C, Targan S, Rotter JI, Fischel-Ghodsian N (1996) Susceptibility locus for inflammatory bowel disease on chromosome 16 has a role in Crohn's disease, but not in ulcerative colitis. Hum Mol Genet 5:1679-1683
39. Parkes M, Satsangi J, Lathrop GM, Bell JI, Jewell DP (1996) Susceptibility loci in inflammatory bowel disease. Lancet 348:1588
40. Cho JH, Fu Y, Kirshner BS, Hanauer SB (1997) Confirmation of a susceptibility locus for Crohn's disease on chromosome 16. Inflamm Bowel Dis 3:186-190
41. Cavanaugh J, Wilson S, Srami M, Stanford P, Gorska M, Foote S, Callen D, Pavli P (1997) Affected sib-pair analysis of pericentromeric chromosome 16 markers in inflammatory bowel disease families. Gastroenterology 112:A946
42. Mirza MM, Lee J, Teare D, Hugot JP, Laurent-Puig P, Colombel JF, Hodgson SV, Thomas G, Easton DF, Lennard-Jones JE, Mathew CG (1998) Evidence of linkage of the inflammatory bowel disease susceptibilkity locus on chromosome 16 (IBD1) to ulcerative colitis. J Med Genet 35:218-221
43. Hampe J, Stokkers P, Nürnberg P, Herrmann T, Theuer D, Scheurlen M, Simon T, Lochs H, Raedler A, van Deventer S, Schreiber S (1997) Linkage to a susceptibility region on chromosome 12 but not 16 in the north central European family sample by multipoint non-parametric linkage analysis. Gastroenterology 112:A990
44. Duerr RH, Barmada MM, Zhang L, Davis S, Preston RA, Chensny LJ, Brown JL, Ehrlich GD, Weeks DE, Aston CE (1998) Linkage and association between inflammatory bowel disease and a locus on chromosome 12. Am J Hum Genet 63:95-100
45. Parkes M, Satsangi J, Jewell DP (1997) Transmission disequilibrium of a marker haplotype fine maps chromosome 12 linkage in IBD. Gut [Suppl] 42:A49
46. Probert CSJ, Jayanthi V, Pinder D, Wicks AC, Mayberry JF (1992) Epidemiological study of ulcerative proctocolitis in Indian migrants and the indigenous population of Leicestershire. Gut 33:687-693
47. Sonnenberg A et Wasserman IH (1991) Epidemiology of inflammatory bowel disease among U. S. military veterans. Gastroenterology 101: 122-130
48. Crohn BB (1934) The broadering conception of regional enteritis. Am J Dig Dis 1:97-99
49. Gilat T, Hacohen D, Lilos P, Langman JS, the international IBD study group (1987) Childhood factors in ulcerative colitis and Crohn's disease. Scand J Gastroenterol 22: 1009-1024
50. Polito JM, Rees RC, Childs B, Mendeloff AI, Harris ML, Bayless TM (1996) Preliminary evidence for genetic anticipation in Crohn's disease. Lancet 347:798-800
51. Colombel JF, Grandbastien B, Gower-Rousseau C, Plegat S, Evrard JP, Dupas JL, Gendre JP, Modigliani R, Belaiche J, Hostein J, Hugot JP, Van Kruiningen H, Cortot A (1996) Clinical characteristics of Crohn's disease in 72 families. Gastroenterology 111:604-607
52. Bennett RA, Rubin PH, Present DH (1991) Frequency of inflammatory bowel disease in offspring of couples both presenting with inflammatory bowel disease. Gastroenterology 100: 1638-1643