Modelling of adrenoceptor ligand targets based on novel medium-or macro- sized fused nitrogen heterocyclic systems

Journal of Computer-Aided Molecular Design

Volumn 13, Issue 1, 1999, Pages 69-78

  Griffith, Renate ^a   Bremner, John B ^a  

^a UNIVERSITY OF WOLLONGONG   (Australia)

Author keywords

Adrenergic receptors; Molecular modelling; Selectivity

Indexed keywords

HYDROGEN BONDS; LIGANDS; NITROGEN; ORGANIC COMPOUNDS;

ADRENERGIC RECEPTORS; BOND CLEAVAGES; CONFORMATIONAL FLEXIBILITY; FUSED RING; GEOMETRIC SHAPE; HETEROCYCLIC COMPOUND; HETEROCYCLIC SYSTEMS; POTENTIAL TARGETS; SELECTIVE LIGANDS; SELECTIVITY;

LEAD COMPOUNDS;

ADRENERGIC RECEPTOR; ALPHA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; ALPHA 1A ADRENERGIC RECEPTOR; ALPHA 2 ADRENERGIC RECEPTOR BLOCKING AGENT; BENZOTHIOPHENE DERIVATIVE; HETEROCYCLIC COMPOUND; ISOQUINOLINE DERIVATIVE; NITROGEN DERIVATIVE;

ARTICLE; COMPUTER AIDED DESIGN; DRUG CONFORMATION; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; DRUG TARGETING; HYDROGEN BOND; LIGAND BINDING; MOLECULAR MIMICRY; MOLECULAR MODEL; PRIORITY JOURNAL;

EID: 0033021193     PISSN: 0920654X     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1008087131806     Document Type: Article

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