Clinical trials of single-drug therapy for the cardiac effects of hypertension

American Journal of Hypertension

Volumn 12, Issue 1 SUPPL. 11, 1999, Pages

  Gottdiener, John S ^a,b  

^a GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

^b GEORGETOWN UNIVERSITY HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACEBUTOLOL; AMLODIPINE; ANTIHYPERTENSIVE AGENT; ATENOLOL; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CAPTOPRIL; CHLORTALIDONE; CLONIDINE; DILTIAZEM; DOXAZOSIN; ENALAPRIL; HYDROCHLOROTHIAZIDE; INDAPAMIDE; ISRADIPINE; PRAZOSIN; THIAZIDE DIURETIC AGENT;

AGING; ANTIHYPERTENSIVE THERAPY; DRUG EFFICACY; HEART LEFT VENTRICLE HYPERTROPHY; HEART LEFT VENTRICLE MASS; HUMAN; HYPERTENSION; PRIORITY JOURNAL; REVIEW; RISK FACTOR;

ANTIHYPERTENSIVE AGENTS; BLOOD PRESSURE; CLINICAL TRIALS; ECHOCARDIOGRAPHY; FOLLOW-UP STUDIES; HEART VENTRICLES; HUMANS; HYPERTENSION; HYPERTROPHY, LEFT VENTRICULAR;

EID: 0033020893     PISSN: 08957061     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0895-7061(98)00209-x     Document Type: Article

References (68)

1. Laennec R: Of hypertrophia, or simple enlargement of the heart, in Laennec R: A Treatise on the Diseases of the Chest. James Webster, Philadelphia; 1823.
2. Burt VL, Whelton P, Roccella EJ, et al: Prevalence of hypertension in the US adult population. Results from the Third National Health and Nutrition Examination Survey, 1988-1991. Hypertension 1995;25:305-313.
3. Messerli FH, Ventura HO, Elizardi DJ: Hypertension and sudden death: increased ventricular ectopic activity in left ventricular hypertrophy. Am J Med 1984;77:18-22.
4. Casale PN, Devereux RB, Milner M: Value of echocardiographic measurement of left ventricular mass in predicting cardiovascular morbid events in hypertensive men. Ann Intern Med 1986;105:173-178.
5. Koren MJ, Devereux RB, Casale PN: Relation of left ventricular mass and geometry to morbidity and mor-tality in uncomplicated essential hypertension. Ann Intern Med 1991;114:345-352.
6. Ghali JK, Liao Y, Simmons B, et al: The prognostic role of left ventricular hypertrophy in patients with or without coronary artery disease. Ann Intern Med 1992;117: 831-836.
7. Levy D, Garrison RJ, Savage DD, et al: Prognostic implications of echocardiographically determined left ventricular mass in the Framingham Heart Study. N Engl J Med 1990;322:1561-1566.
8. Devereux RB, Pickering TG, Alderman MG: Left ventricular hypertrophy in hypertension: prevalence and relationship to pathophysiologic variables. Hypertension 1987;9(suppl 2):II-53-II-59.
9. Levy D, Anderson KM, Savage DD, et al: Echocardiographically detected left ventricular hypertrophy: prevalence and risk factors. The Framingham Heart Study. Ann Intern Med 1988;108:7-13.
10. Gottdiener JS, Reda DJ, Materson BJ, et al: Importance of obesity, race and age to the cardiac structural and functional effects of hypertension. J Am Coll Cardiol 1994;24:1492-1498.
11. Roman MJ, Pickering TG, Fini R, et al: Prevalence and determinants of cardiac and vascular hypertrophy in hypertension. Hypertension 1995;26:369-373.
12. Levy D, Salomon M, D'Agostino RB, et al: Prognostic implications of baseline electrocardiographic features and their serial changes in subjects with left ventricular hypertrophy. Circulation 1994;90:1786-1793.
13. Verdecchia P, Schillaci G, Borgioni C, et al: Prognostic significance of serial changes in left ventricular mass in essential hypertension. Circulation 1998;97:48-54.
14. Liebson PR: Clinical studies of drug reversal of hypertensive left ventricular hypertrophy. Am J Hypertens 1990;3:512-517.
15. Trimarco B, Wikstrand J: Regression of cardiovascular structural changes by antihypertensive treatment. Functional consequences and time course of reversal as judged from clinical studies. Hypertension 1984;6(suppl 3):III-150.
16. Schulman S, Weiss J, Becker L, et al: The effects of antihypertensive therapy on left ventricular mass in elderly patients. N Eng J Med 1990;322:1350-1356.
17. Sen S. Regression of cardiac hypertrophy. Experimental animal model. Am J Med 1983;75(suppl 3A):87.
18. Fouad-Tarazi F, Liebson PR: Echocardiographic studies of regression of left ventricular hypertrophy in hypertension. Hypertension 1987;4(suppl 2):65-68.
19. Tarazi RC, Sen S, Fouad FM, Wicker P: Regression of myocardial hypertrophy: conditions and sequelae of reversal in hypertensive heart disease, in Alpert NR (ed): Perspectives in Cardiovascular Research. 7th Ed. Raven Press, New York, 1983, pp 637.
20. Massie BM: Effect of diuretic therapy on hypertensive left ventricular hypertrophy. Eur Heart J 1992;13(suppl G):53-60.
21. Pfeffer MA, Pfeffer JM: Reversing cardiac hypertrophy in hypertension. N Engl M Med 1987;322:1388-1390.
22. Devereux RB, Savage DD, Sachs I, Laragh JH: Effect of blood pressure control on left ventricular hypertrophy and function in hypertension. Circulation 1980; 62(suppl 3):36.
23. Wollam GL, Hall WD, Porter VD, et al: Time course of regression of left ventricular hypertrophy in treated hypertensive patients. Am J Med 1983;26:100-110.
24. Drayer JIM, Gardin JM, Weber MA, Aronow WS: Changes in ventricular septal thickness during diuretic therapy. Clin Pharmacol Therap 1982;32:283-288.
25. Giles TD, Sander GE, Roffidal LC, et al: Comparison of nitrendipine and hydrochlorothiazide for systemic hypertension. Am J Cardiol 1987;60:103-106.
26. Liebson P: Echocardiographic assessment of the left ventricle in hypertension: perspectives on epidemiologic studies and clinical trials. J Vase Biol Med 1993;4: 285-310.
27. Dahlof B, Pennert K, Hansson L: Reversal of left ventricular hypertrophy in hypertensive patients: a metaanalysis of 109 treatment studies. Am J Hypertens 1992; 5:95-110.
28. Schmieder RE, Martus P, Klingbeil A: Reversal of left ventricular hypertrophy in essential hypertension: a meta-analysis of randomized double-blind studies. JAMA 1996;275:1507-1513.
29. Grandits G, Liebson P, Dianzumba S, Prineas R: Echocardiography in multicenter clinical trials: experience from the Treatment of Mild Hypertension Study. Controlled Clin Trials 1994;15:395-410.
30. Liebson PR, Grandits GA, Dianzumba S, et al: Comparison of five antihypertensive monotherapies and placebo for change in left ventricular mass in patients receiving nutritional-hygienic therapy in the Treatment of Mild Hypertension Study (TOMHS). Circulation 1995;91:698-706.
31. Neaton JD, Grimm RJ, Jr, Prineas RJ, et al: Treatment of Mild Hypertension Study. Final results. Treatment of Mild Hypertension Study Research Group. JAMA 1993; 270:713-724.
32. Materson BJ, Reda DJ, Cushman WC, et al: Single-drug therapy for hypertension in men. A comparison of six antihypertensive agents with placebo. The Department of Veterans Affairs Cooperative Study Group on Antihypertensive Agents. N Engl J Med 1993;328:914-921.
33. Gottdiener J, Reda D, Massie BM, et al: Effect of single-drug therapy on reduction of left ventricular mass in mild to moderate hypertension: comparison of six antihypertensive agents. The Department of Veterans Affairs cooperative study group on antihypertensive agents. Circulation 1997;95:2007-2014.
34. Papademetriou P, Gottdiener JS, Narayan P, et al: Isradipine vs hydrochlorothiazide for reduction of LV mass in hypertension: results of a multicenter trial. J Am Coll Cardiol 1997;30:1802-1808.
35. SHEP Cooperative Research Group: Prevention of stroke by antihypertensive drug treatment in older persons with hypertension. Systolic Hypertension in the Elderly Program (SHEP). JAMA 1991;265:3255-3263.
36. Ofili EO, Cohen JD, St. Vrain JA, et al: Effect of treatment of isolated systolic hypertension on left ventricular mass. JAMA 1998;279:778-780.
37. Curry CL, Robinson H, Brown R, et al: Regression of left ventricular hypertrophy in patients with essential hypertension: results of 6 month treatment with indapamide. Am J Hypertens 1996;9:828-832.
38. Carey PA, Sheridan DJ, de Cordoue A, Guez D: Effect of indapamide on left ventricular hypertrophy in hypertension: a meta-analysis. Am J Cardiol 1996;77:17b-19b.
39. Tan SA, Berk LS, Tan LG: Indapamide regresses, but transdermal clonidine does not regress, left ventricular hypertrophy in hypertensive diabetic patients. Am J Cardiol 1996;77:20B-22B.
40. McMahon S, Wilcken D, Macdonald G: The effect of weight reduction on left ventricular mass. N Eng J Med 1986;314:334-339.
41. Kelemen MH, Effron MB, Valenti SA, Stewart KJ: Exercise training combined with antihypertensive drug therapy: effects on lipids, blood pressure, and left ventricular mass. JAMA 1990;263:2766-2771.
42. Kokkinos PF, Narayan P, Colleran JA, et al: Effects of regular exercise on blood pressure and left ventricular hypertrophy in African-American men with severe hypertension. N Engl J Med 1995;333:1462-1467.
43. Ferrara L, De Simone G, Pasanisi F, Mancini M: Left ventricular mass reduction during salt depletion in arterial hypertension. Hypertension 1984;6:755-759.
44. Jula A, Karanko H: Effects on left ventricular hypertrophy of long-term nonpharmacological treatment with sodium restriction in mild-to-moderate essential hypertension. Circulation 1994;89:1023-1031.
45. Khatri IM, Gottdiener JS, Notargiacomo AV, Preis E: The effect of therapy on left ventricular function in hypertension. Clin Sci 1980;59:435s-439s.
46. Phillips RA, Ardeljan M, Shimabukuro S: Normalization of left ventricular mass and associated changes in neurohormones and atrial natriuretic peptide after 1 year of sustained nifedipine therapy for severe hypertension. J Am Coll Cardiol 1991;17:1595-1602.
47. Oren S, Messerli FH, Grossman E, et al: Immediate and short-term cardiovascular effects of fosinopril, a new angiotensin-converting enzyme inhibitor, in patients with essential hypertension. J Am Coll Cardiol 1991;17: 1183-1187.
48. Aurigemma G, Gottdiener J, Gaasch W, et al: Ventricular and myocardial function following regression of hypertensive left ventricular hypertrophy (abst). J Am Coll Cardiol 1995;27:215A.
49. Trimarco B, DeLuca N, Rosiello G: Improvement of diastolic function after reversal of left ventricular hypertrophy induced by long-term antihypertensive treatment with tertatolol. Am J Cardiol 1989;64:745-751.
50. Muiesan ML, Agabiti-Rosei E, Romanelli G: Improved left ventricular systolic and diastolic function after regression of cardiac hypertrophy, treatment withdrawal, and redevelopment of hypertension. J Cardiovasc Pharmacol 1991;17(suppl 2):S179-S181.
51. Gottdiener JS: Measureing diastolic function. J Am Coll Cardiol 1991;18:83-84.
52. Clement D, DeBuyzere M, Dupres D: Left ventricular function and regression of left ventricular hypertrophy in essential hypertension. Am J Hypertens 1993;6:14S-19S.
53. Muiesan ML, Salvetti M, Rizzoni D, et al: Association of change in left ventricular mass with prognosis during long-term antihypertensive treatment. J Hypertens 1995;13:1091-1095.
54. Miller JT, O'Rourke RA, Crawford MH: Left atrial enlargement: an early sign of hypertensive disease. Am Heart J 1988;116:1048-1051.
55. Pearson AC, Gudipati C, Nagelhout D, et al: Echocardiographic evaluation of cardiac structure and function in elderly subjects with isolated systolic hypertension. J Am Coll Cardiol 1991;17:422-430.
56. Vaziri S, Lauer M, Larson M, et al: Influence of blood pressure on left atrial size. Hypertension 1995;25:1155-1160.
57. Gottdiener JS, Reda DJ, Williams DW, Materson BJ: Left atrial size in hypertensive men: influence of obesity, race, and age. J Am Coll Cardiol 1997;29:651-658.
58. Henry W, Morganroth J, Pearlman A, et al: Relation between echocardiographically determined left atrial size and atrial fibrillation. Circulation 1976;53:273-279.
59. Keren G, Etzion T, Sherez J, et al: Atrial fibrillation and atrial enlargement in patients with mitral stenosis. Am Heart J 1987;114:1146-1155.
60. The Stroke Prevention in Atrial Fibrillation Investigators: Predictors of thromboembolism in atrial fibrillation: II. Echocardiographic features of patients at risk. Ann Intern Med 1992;116:6-12.
61. Qian XX, Chen AH, Deng JY, et al: The effect of Isoptin SR on blood pressure, heart function and hypertrophy of left ventricle of hypertensive patients. Chin Med J 1994;107:260-264.
62. 2+ blocker verapamil (Calan-SR) in hypertensive patients. J Cardiovasc Pharmacol 1993;22:637-643.
63. Kaul U, Mohan JC, Bhatia ML: Effects of labetalol on left ventricular mass and function in hypertension-an assessment by serial echocardiography, Int J Cardiol 1984;5:461-473.
64. Gottdiener J, Reda D, Williams D, et al: Effect of single-drug therapy on reduction of left atrial size in mild to moderate hypertension: comparison of six antihypertensive agents. The Department of Veterans Affairs Cooperative Study Group on Antihypertensive Agents. Circulation 1998;98:140-148.
65. Kostis JB, Davis BR, Cutler J, et al: Prevention of heart failure by antihypertensive drug treatment in older persons with isolated systolic hypertension. SHEP Cooperative Research Group. JAMA 1997;278:212-216.
66. Furberg CD, Cutler JA: Diuretic agents versus beta-blockers: comparison of effects on mortality, stroke, and coronary events. Hypertension 1989;13:I57-I61.
67. Curb JD, Pressel SL, Cutler JA, et al: Effect of diuretic-based antihypertensive treatment on cardiovascular disease risk in older diabetic patients with isolated systolic hypertension. Systolic Hypertension in the Elderly Program cooperative research group. JAMA 1996;276:1886-1892.
68. Pahor M, Guralnik JM, Corti MC, et al: Long-term survival and use of antihypertensive medications in older persons. J Am Geriatr Soc 1995;43:1191-1197.