Murine B-cell and T-cell epitopes of the allergen Hev b 5 from natural rubber latex

Molecular Immunology

Volumn 36, Issue 2, 1999, Pages 135-143

  Slater, J E ^a   Paupore, E J ^a   O'Hehir, R E ^b  

^a CHILDREN S RESEARCH INSTITUTE   (United States)

^b Department of Allergy   (Australia)

Author keywords

B cell; Epitope; Hev b 5; Immunotherapy; Latex; Mouse; T cell

Indexed keywords

EPITOPE; LATEX; RUBBER;

ANIMAL CELL; ARTICLE; B LYMPHOCYTE; CONTROLLED STUDY; EPITOPE MAPPING; IMMUNOTHERAPY; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPLEEN CELL; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION;

ALLERGENS; AMINO ACID SEQUENCE; ANIMALS; ANTIGEN PRESENTATION; B-LYMPHOCYTES; EPITOPES; LATEX HYPERSENSITIVITY; LYMPHOCYTE COOPERATION; MICE; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PLANT PROTEINS; SEQUENCE ANALYSIS; T-LYMPHOCYTES;

ANIMALIA; MURINAE;

EID: 0033020721     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0161-5890(99)00021-8     Document Type: Article

References (18)

1. Akasawa A., Hsieh L.S., Martin B.M., Liu T., Lin Y. A novel acidic allergen, Hev b 5, in latex: purification, cloning and characterization. J. Biol. Chem. 271:1996;25389-25393.
2. Casares S., Inaba K., Brumeanu T.D., Steinman R.M., Bona C.A. Antigen presentation by dendritic cells after immunization with DNA encoding a major histocompatibility complex class II-restricted viral epitope. J. Exp. Med. 186:1997;1481-1486.
3. Ciernik I.F., Berzofsky J.A., Carbone D.P. Induction of cytotoxic T lymphocytes and antitumor immunity with DNA vaccines expressing single T-cell epitopes. J. Immunol. 156:1996;2369-2375.
4. Condon C., Watkins S.C., Celluzzi C.M., Thompson K., Falo L.D. Jr. DNA-based immunization by in vivo transfection of dendritic cells. Nature Medicine. 2:1996;1122-1128.
5. Hsieh L.S., Martin B.M., Doherty A.E., Lin Y. Determination of major IgE-binding epitopes of a latex acidic allergen, Hev b 5. J. Allergy Clin. Immunol. 99:1997;S342. (Abstract).
6. Hsu C.H., Chua K.Y., Tao M.H., Huang S.K., Hsieh K.H. Inhibition of specific IgE response in vivo by allergen-gene transfer. Int. Immunol. 8:1996;1405-1411.
7. Hsu C.H., Chua K.Y., Tao M.H., Lai Y.L., Wu H.D., Huang S.K., Hsieh K.H. Immunoprophylaxis of allergen-induced immunoglobulin E synthesis and airway hyperresponsiveness in vivo by genetic immunization. Nature Medicine. 2:1996;540-544.
8. Kneller D.G., Cohen F.E., Langridge R. Improvements in protein secondary structure prediction by an enhanced neural network. J. Mol. Biol. 214:1990;171-182.
9. Lamb J.R., Tsitoura D.C., Hoyne G.F. Peptide mediated modulation of allergen specific immune responses. Arb. Paul Ehrlich Inst. Bundesamt Sera Impfstoffe Frankf. A. M. 91:1997;14-20.
10. Norman P.S. Responses to T cell tolerogenic peptides. Arb. Paul Ehrlich Inst. Bundesamt Sera Impfstoffe Frankf. A. M. 91:1997;40-44.
11. Raz E., Tighe H., Sato Y., Corr M., Dudler J.A., Roman M., Swain S.L., Spiegelberg H.L., Carson D.A. Preferential induction of a Th1 immune response and inhibition of specific IgE antibody formation by plasmid DNA immunization. Proc. Natl. Acad. Sci. USA. 93:1996;5141-5145.
12. Slater J.E. Latex allergy. Kay A.B. Allergy and allergic diseases. 1997;981 Blackwell Science, Oxford.
13. Slater J.E., Colberg-Poley A.M. A DNA vaccine for allergen immunotherapy using the latex allergen Hev b 5. Arb. Paul Ehrlich Inst. Bundesamt Sera Impfstoffe Frankf. A. M. 91:1997;230-235.
14. Slater J.E., Paupore E., Zhang Y.T., Colberg-Poley A.M. The latex allergen Hev b 5 transcript is widely distributed after subcutaneous injection in BALB/c mice of its DNA vaccine. J. Allergy Clin. Immunol. 102:1998;469-475.
15. Slater J.E., Paupore E.J., Elwell M.R., Truscott W. Lipopolysaccharide augments IgG and IgE responses of mice to the latex allergen Hev b 5. J. Allergy Clin. Immunol. 102:1998;977-983.
16. Slater J.E., Vedvick T., Arthur-Smith A., Trybul D.E., Kekwick R.G.O. Identification, cloning and sequence of a major allergen (Hev b 5) from natural rubber latex (Hevea brasiliensis). J. Biol. Chem. 271:1996;25394-25399.
17. Toci G., Shah S., Al-Faqih A., Beezhold D., McGeady S.J. Oral latex desensitization of healthcare workers. J. Allergy Clin. Immunol. 101:1998;S161. (Abstract).
18. Torres C.A.T., Iwasaki A., Barber B.H., Robinson H.L. Differential dependence on target site tissue for gene gun and intramuscular DNA immunization. J. Immunol. 158:1997;4529-4532.