Mechanisms underlying increased platelet reactivity in patients with peripheral arterial disease. Preliminary results

International Angiology

Volumn 18, Issue 2, 1999, Pages 163-170

  Reininger, C B ^a   Boeger, C A ^a   Steckmeier, B ^a   Spannagl, M ^a   Scweiberer, L ^a  

^a NONE

Author keywords

Blood platelets physiology; Peripheral vascular diseases; Platelet adhesiveness; Platelet aggregation

Indexed keywords

ACETYLSALICYLIC ACID; ADENOSINE DIPHOSPHATE; FIBRINOGEN; FIBRINOGEN RECEPTOR; FIBRINOGEN RECEPTOR ANTAGONIST; HEPARIN;

AFIBRINOGENEMIA; ARTERY DISEASE; ARTICLE; ATHEROSCLEROSIS; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG HYPERSENSITIVITY; DRUG RESISTANCE; GEL FILTRATION; HEMOSTASIS; HUMAN; HUMAN CELL; INTRAVENOUS DRUG ADMINISTRATION; PERIPHERAL VASCULAR DISEASE; THROMBOCYTE ADHESION; THROMBOCYTE AGGREGATION; THROMBOCYTE FUNCTION; THROMBOSIS;

ACETIC ACIDS; ADULT; BENZAMIDES; BLOOD PLATELETS; FEMALE; FIBRINOLYTIC AGENTS; HUMANS; MALE; PERIPHERAL VASCULAR DISEASES; PLATELET ADHESIVENESS; PLATELET AGGREGATION;

EID: 0033020508     PISSN: 03929590     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. European Working Group on Critical Leg Ischemia. Second European consensus document on chronic critical leg ischemia. Circulation 1991, 84(Suppl IV):28-34.
2. Criqui MH, Langer RD, Fronek A, Feigelson HS, Klauber MR, McCann TJ et al. Mortality over a period of 10 years in patients with peripheral arterial disease. N Engl J Med 1992;326:381-6.
3. Debuyzere M, Philippe J, Duprez D, Baele G, Clement DL. Coagulation system activation and increase of D-Dimer levels in peripheral arterial occlusive disease. Am J Hematol 1993;43:91-4.
4. Fowkes FGR, Lowe GDO, Housley E, Rattray A, Rümley A, Elton RA et al. Cross-linked fibrin degradation products, progression of peripheral arterial disease and risk of coronary heart disease. Lancet 1993;342:84-6.
5. Reininger CB, Graf J, Reininger AJ, Spannagl M, Steckmeier B, Schweiberer L. Increased platelet and coagulatory activity indicate ongoing thrombogenesis in peripheral arterial disease. Thromb Res 1996;82:523-32.
6. Reininger CB, Greinacher A, Graf J, Lasser R, Steckmeier B, Schweiberer L. Platelets of patients with peripheral arterial disease are hypersensitive to heparin. Thromb Res 1996;6:641-9.
7. Ruggeri ZM. New insights into the mechanisms of platelet adhesion and aggregation. Sem Hematol 1994;3:229-39.
8. Copley A. The endoendothelial fibrin lining, fibrinogen gel clotting and the endothelium-blood interface. Ann NY Acad Sci 1983;416:377-96.
9. Silberberg A. Macromolecular surface films at a solid/liguid interface. In: Copley A, editor. The endoendothelial fibrin lining. Oxford: Pergamon Press, 1993:55-9.
10. Peerschke EIB. Stabilization of platelet-fibrinogen interactions is an integral property of the GP IIb/IIIa complex. J Lab Clin Med 1994;124:439-46.
11. Savage B, Ruggeri ZN. Modulation of platelet function through adhesion receptors: A dual role for glycoprotein IIb-IIIa mediated by fibrinogen and glycoprotein Ib-von Willebrand factor. J Biol Chem 1992;267:11300-6.
12. Reininger CB, Reininger AJ, Graf J, Eibl-Eibesfeldt BI, Steckmeier B. Real-time analysis of platelet adhesion under stagnation point flow conditions: the effect of red blood cells and glycoprotein IIb/IIIa receptor blockade. J Vasc Invest 1996;2:1-11.
13. Reininger CB , Lasser R, Rumitz M, Böger C, Schweiberer L. Computational analysis of platelet adhesion and aggregation under stagnatiojn point flow conditions. Comp Med Biol, in press.
14. Silver WP, Keller MP, Teel RT, Silver DS. Effects of donor characteristics, in vitro time and temparature on platelet aggregometry. J Vasc Surg 1993;17:726-33.
15. Rose GA. The diagnosis of ischaemic heart pain and intermittant claudication in filed surveys. Bull World Health Organ 1962;27:645-58.
16. Lelah MD. Cooper SL. Basic concepts in blood-material interactions. In: Lelah MD, Cooper SL, editors. Polyurethanes in Medicine. New York: Boca Raton, CRC Press, 1986:125-35.
17. Zucker MB, Vroman L. Platelet adhesion induced by fibrinogen adsorbed onto glass. Proc Soc Exp Biol Med 1969;131:318-20.
18. Stanford ME, Munoz PC, Vroman I. Platelets adhere where flow has left fibrinogen on glass. Ann NY Acad Sci 1983;416:504-12.
19. Salzman EW, Merrill EW, Kent KC. Interaction of blood with artificial surfaces. In: Colman RW, Hirsch J, Marder VJ, Salzman JB, editors. Hemostasis and thrombosis: basic principles and clinical practice. 3rd edition. Philadelphia: Lippincott Company, 1994:1469-85.
20. Coller BS, Scudder LE, Beer J, Gold HK, Folts JB, Cavagnaro J et al. Monoclonal antibodies to platelet glycoprotein IIb/IIIa as antithrombotic agents. In: Part IV. Adhesive receptors in hemostasis and thrombosis. Ann NY Acad Sci 1991;614:193-213.
21. McPherson J, Zucker MB. Platelet retention in glass bead columns: Adhesion to glass and subsequent platelet-platelet interactions. Blood 1975;47:55-67.
22. Reininger CB, Böger CA, Steckmeier B, Lasser R, Schwieberer L. In vitro and in vivo effects of PGE1 on the platelet function of patients with critical limb ischemia: Preliminary results. Thromb Haemost 1997;78(Suppl):128.
23. Coller BS. Interaction of normal, thrombasthenic, and Bernard-Soulier platelets with immobilized fibrinogen: Defective fibrinogen interaction in thrombasthenia. Blood 1980;55:169-77.
24. Ruggeri Z. The role of von Willebrand Factor and fibrinogen in the initiation of platelet adhesion to thrombogenic surfaces. Thromb Haemost 74:460-3.
25. Coller BS, Anderson K, Weisman HF. New antiplatelet agents. Thromb Haemost 1995;74:302-8.
26. Reverter JC, Beguin S, Kessels H, Kumar R, Hemker HC, Coller BS. Inhibition of platelet-mediated, tissue factor-induced thrombin generation by the mouse/human chimeric 7E3 antibody. J Clin Invest 1995;98:863-74.
27. Fowkes FGR, Connor JM, Smith FB, Wood J, Donnan PT, Lowe GDO. Fibrinogen genotype and risk of peripheral atherosclerosis. Lancet 1992;339:693-6.
28. Reininger CB, Reininger AJ, Steckemeier B, Greinacher A, Lasser R, Schweiberer. Platelet response to vascular surgery: A preliminary study on the effect of aspirin and heparin. Thromb Res 1994;1:79-87.
29. Hach-Wunderle V, Kainer K, Salzmann G, Müller-Berghaus G, Potzsch B. Heparin-related thrombosis despite normal platelet counts in vascular surgery. Am J Surg 1997;173:117-9.
30. Salzman EW, Rosenberg RD, Smith MH. Effect of heparin and heparin fractions on platelet aggregation. J Clin Invest 1980;65:64-72.
31. McDanaugh J, Carrel N, Myoung H. Dysfibrinogenemia and other disorders of fibrinogen structure and function. In: Colman RW, Hirsch J, Marder VJ, Salzman JB, editors. Hemostasis and thrombosis: basic principles and clinical practice. 3rd edition. Philadelphia: Lippincott Company, 1994:314-34.