Synovial sarcoma of the extremities: A clinicopathologic study of 34 cases, including semi-quantitative analysis of spindled, epithelial, and poorly differentiated areas

American Journal of Surgical Pathology

Volumn 23, Issue 3, 1999, Pages 268-275

  Machen, S Karen ^a   Easley, Kirk A ^a   Goldblum, John R ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

Extremities; Poorly differentiated synovial sarcoma; Synovial sarcoma

Indexed keywords

ADOLESCENT; ADULT; AGED; ARTICLE; CANCER LOCALIZATION; CANCER RECURRENCE; CELL TYPE; CHILD; CLINICAL ARTICLE; FEMALE; HUMAN; HUMAN TISSUE; LIMB AMPUTATION; MALE; PROGNOSIS; SARCOMA; SYNOVIAL SARCOMA; TREATMENT OUTCOME;

ADOLESCENT; ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; CALCINOSIS; CELL NUCLEUS; CHILD; EPITHELIAL CELLS; EXTREMITIES; FEMALE; HUMANS; MALE; MIDDLE AGED; MITOTIC INDEX; NECROSIS; PROGNOSIS; SARCOMA, SYNOVIAL; SOFT TISSUE NEOPLASMS;

EID: 0033019249     PISSN: 01475185     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000478-199903000-00004     Document Type: Article

References (33)

1. Argani P, Zakowski MF, Klimstra DS, Rosai J, Ladanyi M. Detection of SYT-SSX chimeric RNA of synovial sarcoma in paraffin-embedded tissue and its application in problematic cases. Mod Pathol 1998;11:65-71.
2. Balazs L, Parham D, Shurtleff S, Poppo A, Downing J. Identification of the t(x;18) as a diagnostic tool in the differential diagnosis of synovial sarcomas versus peripheral nerve sheath tumors. Mod Pathol 1997;10:23A.
3. Cagle LA, Mirra JM, Storm FK, Roe DJ, Eilber FR. Histologic features relating to prognosis in synovial sarcoma. Cancer 1987; 59:1810-4.
4. Clark J, Rocques PJ, Crew AJ, et al. Identification of novel genes, SYT and SSX, involved in the t(x;18)(p11.2;q11.2) translocation found in human synovial sarcoma. Nat Genet 1994;7:502-8.
5. Costa J, Wesley RA, Glatstein E, Rosenberg SA. The grading of soft tissue sarcomas. Results of a clinicohistopathologic correlation in a series of 163 cases. Cancer 1984;53:530-41.
6. El-Naggar AK, Ayala AG, Abdul-Karim FW, et al. Synovial sarcoma. A DNA flow cytometric study. Cancer 1990;65:2295-300.
7. Enzinger FM, Weiss SW (editors). Synovial sarcoma. In: Soft tissue tumors. Philadelphia: Mosby; 1995:757-86.
8. Evans HL. Synovial sarcoma. A study of 23 biphasic and 17 probable monophasic examples. Pathol Annu 1980;15:309-31.
9. Fetsch JF, Meis JM. Synovial sarcoma of the abdominal wall. Cancer 1993;72:469-77.
10. Golouh R, Vuzevski V, Bracko M, Heul RO, Cervek J. Synovial sarcoma. A clinicopathological study of 36 cases. J Surg Oncol 1990;45:20-8.
11. Griffin CG, Emanuel BS. Translocation (x;18) in a synovial sarcoma. Cancer Gener Cytogenel 1987;26:181-3.
12. Hajdu SI, Shiu MH, Former JG. Tendosynovial sarcoma. A clinicopathological study of 136 cases. Cancer 1977;39:1201-17.
13. Kampe CE, Rosen G, Eilber F, et al. Synovial sarcoma: a study of intensive chemotherapy in 14 patients with localized disease. Cancer 1993;72:2161-9.
14. Kawai A, Woodruff J, Healey JH, Brennan MF, Antonescu CR, Ladanyi M. SYT-SSX gene fusion as a determinant of morphology and prognosis in synovial sarcoma. N Engl J Med 1998;338:153-60.
15. Kindblom LG, Meis-Kindblom JM, Bertoni F, et al. Synovial sarcoma: identification of low and high risk groups. Mod Pathol 1996;9:28A.
16. Kodet R, Newton WA Jr, Sachs N, Hamoudi AB, Raney RB, Asmar L, Gehan EA. Rhabdoid tumors of soft tissues: a clinicopathologic study of 26 cases enrolled on the Intergroup Rhabdomyosarcoma Study. Hum Pathol 1991;22:674-84.
17. Krall RA, Kostianovsky M, Patchefsky AS. Synovial sarcoma. A clinical, pathological, and ultrastructural study of 26 cases supporting the recognition of a monophasic variant. Am J Surg Pathol 1981;5:137-51.
18. Lee MS, Hajdu SI, Exelby PR. Synovial sarcoma in children. Surg Gynecol Obstet 1974;138:701-4.
19. Milchgrub S, Ghandur-Mnaymneh L, Dorfman HD, Albores-Saavedra J. Synovial sarcoma with extensive osteoid and bone formation. Am J Surg Pathol 1993;17:357-63.
20. Mirra JM, Wang S, Bhuta S. Synovial sarcoma with squamous differentiation of its mesenchymal glandular elements. A case report with light-microscopic, ultramicroscopic, and immunologic correlation. Am J Surg Pathol 1984;8:791-6.
21. Nagao K, Ito H, Yoshida H. Chromosomal translocation t(x;18) in human synovial sarcomas analyzed by fluorescence in-situ hybridization using paraffin-embedded tissue. Am J Pathol 1996;148: 601-9.
22. Oda Y, Hashimoto H, Tsuneyoshi M, Takeshita S. Survival in synovial sarcoma: a multivariate study of prognostic factors with special emphasis on the comparison between early death and long-term survival. Am J Surg Pathol 1993;17:35-44.
23. Parham DM, Weeks DA, Beckwith JB. The clinicopathologic spectrum of putative extrarenal rhabdoid tumors: an analysis of 42 cases studied with immunohistochemistry or electron microscopy. Am J Surg Pathol 1994;18:1010-29.
24. Rajpal S, Moore RH, Karakousis CP. Synovial sarcoma. A review of treatment and survival in 52 patients. N Y State J Med 1984; 84:17-9.
25. Rööser B, Willen H, Hugoson A, Rydholm A. Prognostic factors in synovial sarcoma. Cancer 1989;63:2182-5.
26. Rosen G, Forscher C, Lowenbraun S, Eilber F, Eckardt J, Holmes C, Fu YS. Synovial sarcoma: uniform response of metastases to high dose Ifosfamide. Cancer 1994;73:2506-11.
27. Schmidt D, Thum P, Med C, Harms D, Treuner J. Synovial sarcoma in children and adolescents. A report from the Kiel Pediatric Tumor Registry. Cancer 1991;67:1667-72.
28. Smith S, Reeves BR, Wong L, Fisher C. A consistent chromosome translocation in synovial sarcoma. Cancer Genet Cytogenet 1987; 26:179-80.
29. Smith TA, Easley KA, Goldblum JR. Myxoid/round cell liposarcoma of the extremities: a clinicopathologic study of 29 cases with particular attention to extent of round cell liposarcoma. Am J Surg Pathol 1996;20:171-80.
30. Tsuneyoshi M, Yokoyama K, Enjoji M. Synovial sarcoma. A clinicopathologic and ultrastructural study of 42 cases. Acta Pathol Jpn 1983;33:23-36.
31. van de Rijn M, Barr FG, Xiong QB, Hedges M, Fisher C. Specificity of RT-PCR for t(x;18) for synovial sarcoma. Mod Pathol 1998;11:71A.
32. Varela-Duran J, Enzinger FM. Calcifying synovial sarcoma. Cancer 1982;50:345-52.
33. Weeks DA, Beckwith JB, Mierau GW, Zuppan CW. Renal neoplasms mimicking rhabdoid tumor of kidney: a report from the National Wilms' Tumor Study Pathology Center. Am J Surg Pathol 1991;15:1042-54.