Dose-dependent shift of apoptotic and unaltered melanocytes into the dermis after irradiation with UVA 1

Dermatology

Volumn 198, Issue 1, 1999, Pages 5-10

  Bacharach Buhles, M ^a   Lubowietzki, M ^b   Altmeyer, P ^b  

^a ST JOSEF HOSPITAL   (Germany)

^b NONE

Author keywords

Apoptosis; Melanocytes; UV irradiation

Indexed keywords

PROTEIN BCL 2; PROTEIN P53;

ADULT; AGED; APOPTOSIS; ARTICLE; BASEMENT MEMBRANE; CELL ACTIVITY; CELL COUNT; CELL PROLIFERATION; CELL SIZE; CONTROLLED STUDY; DERMIS; ELECTRON MICROSCOPY; EPIDERMIS; HISTOCHEMISTRY; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; HUMAN TISSUE; MELANOCYTE; MELANOGENESIS; NORMAL HUMAN; PRIORITY JOURNAL; RADIATION DOSE; STAINING; ULTRAVIOLET A RADIATION;

ADULT; AGED; AGED, 80 AND OVER; APOPTOSIS; DERMIS; DOSE-RESPONSE RELATIONSHIP, RADIATION; FEMALE; HUMANS; HYPERPIGMENTATION; IMMUNOHISTOCHEMISTRY; MALE; MELANOCYTES; MICROSCOPY, ELECTRON; MIDDLE AGED; PROTO-ONCOGENE PROTEINS C-BCL-2; SILVER NITRATE; SKIN; TUMOR SUPPRESSOR PROTEIN P53; ULTRAVIOLET RAYS;

EID: 0033018554     PISSN: 10188665     EISSN: None     Source Type: Journal    
DOI: 10.1159/000018056     Document Type: Article

References (17)

1. Nakagawa H, Rhodes AR, Momtaz-T K, Fitzpatrick TB: Morphologic alterations of epidermal melanocytes and melanosomes in PUVA-lentigines: A comparative ultrastructural investigation of lentigines induced by PUVA and sunlight. J Invest Dermatol 1984; 82:101-107.
2. 2 but not MSH stimulate the proliferation of pigment cells in the pinnal epidermis of the DBA/2 mouse. J Invest Dermatol 1986;86:433-437.
3. Youn JI, Lee AY, Lee YS: The effect of ultraviolet irradiation on epidermal melanocytes and the influence of sunscreen: A histochemical and ultrastructural study. Seoul J Med 1990;31: 253-262.
4. Rosdahl IK, Szabo G: Thymidine labelling of epidermal melanocytes in UV-irradiated skin. Acta Derm Venereol (Stockh) 1976;56:159-162.
5. Lee KH, Bang D, Lee W: Photochemotherapy-induced lentigines on a vitiliginous patch. Electron microscopic observations. Yonsei Med J 1988;29:66-71.
6. Kerr JF, Wyllie AH, Currie AR: Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 1972;26:239-257.
7. Kumakiri M, Hashimoto K, Willis I: Biologic changes due to long-wave ultraviolet irradiation on human skin: Ultrastructural study. J Invest Dermatol 1977;69:392-400.
8. Young AR: The sunburn cell. Photodermatology 1987;4:127-134.
9. Mackie RM, Clelland DB, Skerrow CJ: Typ IV collagen and laminin staining patterns in benign and malignant cutaneous lesions. J Clin Pathol 1989;42:1173-1177.
10. Van Duinen CM, Fleuren GJ, Bruijn JA: The extracellular matrix in pigmented skin lesions: An immunohistological study. Histopathology 1994;24:33-40.
11. Montgomery AM, De Clerk Y, Langley KE, Reisfeld RA, Mueller BM: Melanoma-mediated dissolution of extracellular matrix: Contribution of urokinase-dependent and metallo-proteinase-dependent proteolytic pathways. Cancer Res 1993;53:693-700.
12. Soter NA: Acute effects of ultraviolet radiation on the skin. Semin Dermatol 1990;9:11-15.
13. Gilchrest BA, Soter NA, Hawk JLM, Barr RM, Black AK, Hensby CN, Mallet AI, Greaves MW, Parrish JA: Histologic changes associated with ultraviolet A-induced erythema in normal human skin. J Am Acad Dermatol 1983;9: 213-219.
14. Kanerva L: Electron microscopic observations of dyskeratosis, apoptosis, colloid bodies and fibrillar degeneration after skin irridiation with dithranol. J Cutan Pathol 1990;17:37-44.
15. Itschev K, Dogramadjiew I, Dourmischev AL: Elektronenmikroskopische Untersuchung der menschlichen Haut nach UV-Bestrahlung. Dermatol Monatsschr 1979;165:209-215.
16. Hollis DE, Scheibner A: Ultrastructural changes in epidermal Langerhans cells and melanocytes in response to ultraviolet irradiation in Australians of Aboriginal and Celtic descent. Br J Dermatol 1988;119:21-31.
17. Pawlowski A, Pawlowski DM, Lea PJ: Effects of UV radiation on ultrastructural of human common pigmented naevi and lentigines. Acta Derm Venereol (Stockh) 1971;71:113-117.